Faculty

Institution

Unit

Venue

W. Matthew Michael

Professor of Biological Sciences

University of Southern California

Affiliations

Natural Sciences

Biological Sciences

College of Letters, Arts and Sciences

Natural Sciences

W. Matthew Michael is currently serving as a Biological Sciences Professor of Biological Sciences at University of Southern California.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

W. Matthew Michael

University of Southern California

Professor of Biological Sciences

You can click a keyword to filter the displayed items

molecular biology genetics cell biology developmental biology molecular cell biology dna repair gene expression molecular and cellular biology dna replication cell signaling genome biology signal transduction protein science replication protein structure nucleic acids nuclear organization rna biology cellular biology molecular regulation protein transport genome instability signaling pathways cell cycle developmental genetics caenorhabditis elegans dna damage xenopus egg extracts mammalian biology structural molecular biology biological chemistry avian biology protein function transcription regulation receptor (biochemistry) small rna rna processing intracellular trafficking cell fate determination nuclear export nuclear import replication forks nuclear transport receptor dna replication forks dna-damage response nuclear science cell death vascular biology cancer cells autophagy molecular structure biomolecular structure liver physiology receptor tyrosine kinases molecular pathways protein evolution long non-coding rna mitochondrial dynamics cellular senescence cell autophagy mitophagy protein chemistry protein phosphorylation cell regulation gene function biological function chromosome biology gene regulation oocytes nuclear export signal novel signal polyprimidine tract-binding protein dna replication checkpoint rna synthesis rna transport continued primer synthesis genomics genome stability plo biology genetic technologies

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Role for the Nuclear Rnai Pathway in Global Transcriptional Silencing in C. Elegans Primordial Germ Cells. bioRxiv (Cold Spring Harbor Laboratory) (2025)

genome biologydevelopmental systemgene expressionrna processingtranscription (biology)developmental cellgeneticsnuclear rnai pathwaymolecular cell biologyprimordial germ cellsdevelopmental biologyrna biologyglobal transcriptional silencing

The Top-2/Condensin II Axis Silences Transcription During Germline Specification in C. Elegans. G3 Genes Genomes Genetics (2024)

Mezmur D BelewEmilie ChienMatthew WongW Matthew Michael

genomicsgenome biologygene expressiontranscription regulationtranscription (biology)geneticsgermline specificationmolecular biologymolecular geneticsdevelopmental biology

Transcriptome Analysis in C. Elegans Early Embryos Upon Depletion of the Topoisomerase 2/Condensin II Axis.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Mezmur D. BelewW. Matthew Michael

genomicstranscriptomegene expressiontranscription (biology)geneticsmolecular and cellular biologymolecular biologytranscriptome analysisdevelopmental biology

Characterization of Factors That Underlie Transcriptional Silencing in C. Elegans Oocytes. PLoS Genetics (2023)

Mezmur D. BelewEmilie ChienW. Matthew Michael

oocytesdevelopmental biologygeneticstranscriptional silencinggene characterizationepigeneticscell biology

Transcriptional Repression During Spermatogenesis in C. Elegans Requires Top-2, Condensin II, and the Met-2 H3K9 Methyltransferase.. PubMed (2023)

Emilie ChienW Matthew Michael

transcription regulationgene expressiontranscriptional repressiongeneticsmolecular biologydevelopmental biology

Delineation of a Minimal Topoisomerase II Binding Protein 1 for Regulated Activation of Atr at Dna Double-Strand Breaks. Journal of Biological Chemistry (2022)

Kenna RuisOanh HuynhKatrina MontalesNina A. BarrW. Matthew Michael

biophysicsmolecular regulationdna double-strand breaksminimal topoisomerase iienzymesbiological inorganic chemistrymolecular biologybiological chemistryregulated activationdna repairstructural biologyprotein scienceepigeneticsbiochemistry

Mrn-Dependent and Independent Pathways for Recruitment of Topbp1 to Dna Double-Strand Breaks. PLoS ONE (2022)

Katrina MontalesKenna RuisHoward LindsayW. Matthew Michael

genomicsgenome biologyepigenomicsdouble-strand breaksindependent pathwaysplo biologygeneticsmolecular biologyepigenetics

Multi-Site Phosphorylation of the Topbp1 Atr Activation Domain Propels Atr Signaling During the Response to Dna Breaks. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Holly SenebandithKenna RuisKatrina MontalesOanh HuynhYasaman Jami-AlahmadiJames A. WohlschlegelW. Matthew Michael

biophysicsmulti-site phosphorylationgeneticsmolecular biologydna repairsignal transduction

Nbs1 Binds Directly to Topbp1 via Disparate Interactions Between the Nbs1 Brct1 Domain and the Topbp1 Brct1 and Brct2 Domains. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Oanh HuynhKenna RuisKatrina MontalesW. Matthew Michael

biomolecular interactionskey siteprotein structuregeneticsbiologymolecular biologystructural biologydisparate interactions

The Condensin II/Top-2 Axis Silences Transcription During Germline Specification in C. Elegans. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Mezmur D. BelewEmilie ChienMatthew WongW. Matthew Michael

transcription (biology)geneticsgermline specificationmolecular biologydevelopmental biologyinsect molecular biology

1
2
3
4
5
6
10 / page

W. Matthew Michael

Professor of Biological Sciences

University of Southern California

Affiliations

Natural Sciences

Biological Sciences

College of Letters, Arts and Sciences

Natural Sciences

W. Matthew Michael is currently serving as a Biological Sciences Professor of Biological Sciences at University of Southern California.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

W. Matthew Michael

University of Southern California

Professor of Biological Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Role for the Nuclear Rnai Pathway in Global Transcriptional Silencing in C. Elegans Primordial Germ Cells. bioRxiv (Cold Spring Harbor Laboratory) (2025)

The Top-2/Condensin II Axis Silences Transcription During Germline Specification in C. Elegans. G3 Genes Genomes Genetics (2024)

Mezmur D BelewEmilie ChienMatthew WongW Matthew Michael

genomicsgenome biologygene expressiontranscription regulationtranscription (biology)geneticsgermline specificationmolecular biologymolecular geneticsdevelopmental biology

Transcriptome Analysis in C. Elegans Early Embryos Upon Depletion of the Topoisomerase 2/Condensin II Axis.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Mezmur D. BelewW. Matthew Michael

genomicstranscriptomegene expressiontranscription (biology)geneticsmolecular and cellular biologymolecular biologytranscriptome analysisdevelopmental biology

Characterization of Factors That Underlie Transcriptional Silencing in C. Elegans Oocytes. PLoS Genetics (2023)

Mezmur D. BelewEmilie ChienW. Matthew Michael

oocytesdevelopmental biologygeneticstranscriptional silencinggene characterizationepigeneticscell biology

Transcriptional Repression During Spermatogenesis in C. Elegans Requires Top-2, Condensin II, and the Met-2 H3K9 Methyltransferase.. PubMed (2023)

Emilie ChienW Matthew Michael

transcription regulationgene expressiontranscriptional repressiongeneticsmolecular biologydevelopmental biology

Delineation of a Minimal Topoisomerase II Binding Protein 1 for Regulated Activation of Atr at Dna Double-Strand Breaks. Journal of Biological Chemistry (2022)

Kenna RuisOanh HuynhKatrina MontalesNina A. BarrW. Matthew Michael

Mrn-Dependent and Independent Pathways for Recruitment of Topbp1 to Dna Double-Strand Breaks. PLoS ONE (2022)

Katrina MontalesKenna RuisHoward LindsayW. Matthew Michael

genomicsgenome biologyepigenomicsdouble-strand breaksindependent pathwaysplo biologygeneticsmolecular biologyepigenetics

Multi-Site Phosphorylation of the Topbp1 Atr Activation Domain Propels Atr Signaling During the Response to Dna Breaks. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Holly SenebandithKenna RuisKatrina MontalesOanh HuynhYasaman Jami-AlahmadiJames A. WohlschlegelW. Matthew Michael

biophysicsmulti-site phosphorylationgeneticsmolecular biologydna repairsignal transduction

Nbs1 Binds Directly to Topbp1 via Disparate Interactions Between the Nbs1 Brct1 Domain and the Topbp1 Brct1 and Brct2 Domains. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Oanh HuynhKenna RuisKatrina MontalesW. Matthew Michael

biomolecular interactionskey siteprotein structuregeneticsbiologymolecular biologystructural biologydisparate interactions

The Condensin II/Top-2 Axis Silences Transcription During Germline Specification in C. Elegans. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Mezmur D. BelewEmilie ChienMatthew WongW. Matthew Michael

transcription (biology)geneticsgermline specificationmolecular biologydevelopmental biologyinsect molecular biology

1
2
3
4
5
6
10 / page

Similar Faculty Members

Susan L Forsburg

Institution

University of Southern California

dna replication

systems biology

Michael Botchan

Institution

University of California, Berkeley

genetic technologies

dna replication

James Wohlschlegel

Institution

University of California, Los Angeles

molecular informatics

bioinformatics

Johannes Walter

Institution

Harvard University

dna helicase

molecular biology

Andrew Emili

Institution

Boston University

interactomics

biomedical informatics

Robert J. Schwartz

Institution

University of Houston

cellular differentiation

stem cell

James Haber

Institution

Brandeis University

genome instability

recombination dynamic

John T. Lis

Institution

Cornell University

theoretical biology

biological computation

Leslie Leinwand

Institution

University of Colorado Boulder

molecular biology

cardiology

Andrew P. McMahon

Institution

University of Southern California

stem cell

regenerative medicine

Similar Faculty Members

Susan L Forsburg

Institution

University of Southern California

dna replication

systems biology

Michael Botchan

Institution

University of California, Berkeley

genetic technologies

dna replication

James Wohlschlegel

Institution

University of California, Los Angeles

molecular informatics

bioinformatics

Johannes Walter

Institution

Harvard University

dna helicase

molecular biology

Andrew Emili

Institution

Boston University

interactomics

biomedical informatics

Robert J. Schwartz

Institution

University of Houston

cellular differentiation

stem cell

James Haber

Institution

Brandeis University

genome instability

recombination dynamic

John T. Lis

Institution

Cornell University

theoretical biology

biological computation

Leslie Leinwand

Institution

University of Colorado Boulder

molecular biology

cardiology

Andrew P. McMahon

Institution

University of Southern California

stem cell

regenerative medicine