Faculty

Institution

Unit

Venue

John T. Lis

Professor

Cornell University

Affiliations

College of Agriculture and Life Sciences

Department of Molecular Biology and Genetics

John T. Lis is currently serving as a College Of Agriculture And Life Sciences Professor at Cornell University.

Honors

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Experiences

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Education

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John T. Lis

Cornell University

Professor

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molecular cell biology gene expression transcription (biology) genetics transcription regulation gene regulation molecular biology nucleic acids transcription factors genome biology cell biology systems biology chromatin insect molecular biology molecular genetics molecular and cellular biology rna processing chromatin remodeling gene function gene structure transcriptome rna biology molecular regulation structural molecular biology epigenetics pol ii developmental genetics transcriptomics technology genomic mechanisms gene regulatory networks biological chemistry developmental system developmental cell nuclear organization rna polymerase ii oncogenes protein science molecular diagnostics biomolecular structure hsp70 gene molecular informatics biomolecules chromosome biology heat shock cancer cells rna polymerase nucleic acid chemistry drosophila melanogaster nucleic acid biomarkers epigenomics cell regulation high-throughput screening rna aptamers proteome research splicing variant dna analysis single molecule biophysics heat shock genes protein genetics epigenetic changes yeast signaling pathways molecular microbiology protein expression rna structure prediction cancer genetics molecular research transcriptional regulation hormonal receptor nascent rna pol ii pausing drosophila cells promoter melting drosophila genes drosophila development gaga factor bioinformatics biology theoretical biology computational biology biological computation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Comprehensive Evaluation of Diverse Massively Parallel Reporter Assays to Functionally Characterize Human Enhancers Genome-Wide. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Junke ZhangAlden King-Yung LeungYutong ZhuLi YaoAvery WillisXiuqi PanAbdullah OzerZhou ZhouKeith SilklenkaAlejandro BerreraJin LiangNathaniel D TippensTimothy E. ReddyJohn T. LisHaiyuan Yu

gene expression profilingchromatin accessibilitycell biologyfunctional genomicsgenomicsepigeneticsgenome biologyhuman genomemolecular cell biologyepigenomicsparallel reporter assaystranscriptomics technologygene expressiongenetics

High-Resolution Reconstruction of Cell-Type Specific Transcriptional Regulatory Processes From Bulk Sequencing Samples. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Li YaoSagar R ShahAbdullah OzerJunke ZhangXiuqi PanTianyu XiaVrushali FangalAlden King-Yung LeungMeihan WeiJohn LisHaiyuan Yu

single-cell analysisfunctional genomicstissue profilesgene expression profilingcell researchbioinformaticsgeneticscell biologygenomicsomicsgene expressionhigh-resolution reconstructioncomputational biologycross-modality deconvolutionsystems biologytranscriptomics technologysingle cell sequencinggenome biologytranscriptome

Robust Regulatory Interplay of Enhancers, Facilitators, and Promoters in a Native Chromatin Context. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Zhou ZhouAlbert LiJunke ZhangHaiyuan YuAbdullah OzerJohn T. Lis

native chromatin contextrobust regulatory interplaychromatin remodelingtranscription factorsfunctional genomicsepigeneticsgenome biologygene regulationtarget genemolecular cell biologyepigenomicstranscription (biology)transcription regulationchromatinsystems biologygene expressiongene regulatory networksgenetics

Simultaneous Measurement of Intrinsic Promoter and Enhancer Potential Reveals Principles of Functional Duality and Regulatory Reciprocity. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Mauricio I. ParamoAlden King-Yung LeungSagar R. ShahJunke ZhangNathaniel D. TippensJin LiangLi YaoYiyang JinXiuqi PanAbdullah OzerJohn T. LisHaiyuan Yu

intrinsic promotertranscription factorsfunctional genomicsgenome biologyfunctional dualitygene regulationmolecular cell biologygene functiontranscription (biology)transcription regulationsystems biologygene expressiongene regulatory networksgenetics

Simultaneous Measurement of Intrinsic Promoter and Enhancer Potential Reveals Principles of Functional Duality and Regulatory Reciprocity. (2025)

Haiyuan YuMauricio ParamoAlden King-Yung LeungSagar ShahJunke ZhangNathaniel TippensJin LiangLi YaoYiyang JinXiuqi PanAbdullah OzerJohn Lis

Transcriptional Stress Induces the Overexpression of Novel Lncrnas That Regulate the Brca1 Locus. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Samantha Cruz-RuizRaphael VidalMayra Furlan-MagarilJohn T. LisMario Zurita

oncogenesnon-coding rnalong non-coding rnabrca1 locuscell biologyfunctional genomicsgenome biologytranscriptional stressgene regulationmolecular cell biologytranscriptional regulationtranscription (biology)transcription regulationgene expressionrna biologygenetics

A Lineage-Specific Nascent Rna Assay Unveils Principles of Gene Regulation in Tissue Biology. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Gopal ChovatiyaAlex B WangPhilip VersluisChris K BaiSean Y HuangMichael DeBerardineJudhajeet RayAbdullah OzerJohn T LisTudorita Tumbar

lineage plasticitynascent rna assayadult skin homeostasisnucleic acidstranscription factorscell biologyfunctional genomicsdevelopmental biologygene regulationmolecular cell biologytranscription (biology)transcription regulationpol iicell lineagegene expressiontranscriptome

Cis-Regulatory Control of Transcriptional Timing and Noise in Response to Estrogen. Cell Genomics (2024)

Matthew Ginley-HidingerHosiana AbeweKyle OsborneAlexandra RicheyNoel KitchenKatelyn L. MortensonErin M. WissinkJohn LisXiaoyang ZhangJason Gertz

low noisecell biologyfunctional genomicsgene regulationtemporal responsemolecular cell biologycis-regulatory controltranscription (biology)transcription regulationchromatinsystems biologygene expressiongene regulatory networks

Directionality of Transcriptional Regulatory Elements. bioRxiv (Cold Spring Harbor Laboratory) (2024)

You ChenSagar R ShahAlden LeungMauricio I. ParamoKelly CochranAnshul KundajeAndrew G. ClarkJohn T. LisHaiyuan Yu

divergent transcriptiontranscriptional regulatory elementsgenomic mechanismstranscription factorsfunctional genomicsgenome biologydistal elementsdevelopmental biologygene regulationmolecular cell biologytranscription (biology)transcription regulationgene expressiongene regulatory networksgeneticsgene structure

Live-Cell Imaging of Rna Pol II and Elongation Factors Distinguishes Competing Mechanisms of Transcription Regulation. Molecular Cell (2024)

Philip VersluisThomas G.W. GrahamVincent EngJonathan EbenezerXavier DarzacqWarren R. ZipfelJohn T. Lis

nucleic acidscell biologydevelopmental biologymolecular cell biologytranscription (biology)transcription regulationrna pol iigene expressionrna biologylive-cell imaging

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John T. Lis

Professor

Cornell University

Affiliations

College of Agriculture and Life Sciences

Department of Molecular Biology and Genetics

John T. Lis is currently serving as a College Of Agriculture And Life Sciences Professor at Cornell University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John T. Lis

Cornell University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Comprehensive Evaluation of Diverse Massively Parallel Reporter Assays to Functionally Characterize Human Enhancers Genome-Wide. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Junke ZhangAlden King-Yung LeungYutong ZhuLi YaoAvery WillisXiuqi PanAbdullah OzerZhou ZhouKeith SilklenkaAlejandro BerreraJin LiangNathaniel D TippensTimothy E. ReddyJohn T. LisHaiyuan Yu

High-Resolution Reconstruction of Cell-Type Specific Transcriptional Regulatory Processes From Bulk Sequencing Samples. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Li YaoSagar R ShahAbdullah OzerJunke ZhangXiuqi PanTianyu XiaVrushali FangalAlden King-Yung LeungMeihan WeiJohn LisHaiyuan Yu

Robust Regulatory Interplay of Enhancers, Facilitators, and Promoters in a Native Chromatin Context. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Zhou ZhouAlbert LiJunke ZhangHaiyuan YuAbdullah OzerJohn T. Lis

Simultaneous Measurement of Intrinsic Promoter and Enhancer Potential Reveals Principles of Functional Duality and Regulatory Reciprocity. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Mauricio I. ParamoAlden King-Yung LeungSagar R. ShahJunke ZhangNathaniel D. TippensJin LiangLi YaoYiyang JinXiuqi PanAbdullah OzerJohn T. LisHaiyuan Yu

Simultaneous Measurement of Intrinsic Promoter and Enhancer Potential Reveals Principles of Functional Duality and Regulatory Reciprocity. (2025)

Haiyuan YuMauricio ParamoAlden King-Yung LeungSagar ShahJunke ZhangNathaniel TippensJin LiangLi YaoYiyang JinXiuqi PanAbdullah OzerJohn Lis

Transcriptional Stress Induces the Overexpression of Novel Lncrnas That Regulate the Brca1 Locus. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Samantha Cruz-RuizRaphael VidalMayra Furlan-MagarilJohn T. LisMario Zurita

A Lineage-Specific Nascent Rna Assay Unveils Principles of Gene Regulation in Tissue Biology. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Gopal ChovatiyaAlex B WangPhilip VersluisChris K BaiSean Y HuangMichael DeBerardineJudhajeet RayAbdullah OzerJohn T LisTudorita Tumbar

Cis-Regulatory Control of Transcriptional Timing and Noise in Response to Estrogen. Cell Genomics (2024)

Matthew Ginley-HidingerHosiana AbeweKyle OsborneAlexandra RicheyNoel KitchenKatelyn L. MortensonErin M. WissinkJohn LisXiaoyang ZhangJason Gertz

Directionality of Transcriptional Regulatory Elements. bioRxiv (Cold Spring Harbor Laboratory) (2024)

You ChenSagar R ShahAlden LeungMauricio I. ParamoKelly CochranAnshul KundajeAndrew G. ClarkJohn T. LisHaiyuan Yu

Live-Cell Imaging of Rna Pol II and Elongation Factors Distinguishes Competing Mechanisms of Transcription Regulation. Molecular Cell (2024)

Philip VersluisThomas G.W. GrahamVincent EngJonathan EbenezerXavier DarzacqWarren R. ZipfelJohn T. Lis

nucleic acidscell biologydevelopmental biologymolecular cell biologytranscription (biology)transcription regulationrna pol iigene expressionrna biologylive-cell imaging

1
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10 / page

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