Faculty

Institution

Unit

Venue

Jurgen Rohr

Vice-Chair and Professor

University of Kentucky

Affiliations

College of Pharmacy

Jurgen Rohr is currently serving as a College Of Pharmacy Vice-Chair and Professor at University of Kentucky.

Honors

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Experiences

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Education

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Jurgen Rohr

University of Kentucky

Vice-Chair and Professor

You can click a keyword to filter the displayed items

pharmacology biochemistry molecular biology biosynthesis medicinal chemistry enzymes biotechnology biological chemistry gene expression natural product biosynthesis genetics enzyme inhibition protein biosynthesis redox biology drug discovery synthetic biology protein science medicinal research chemical biology cancer treatment anti-cancer agents cancer biology biochemical sciences natural product research tumor targeting biocatalysis pharmacotherapy molecular science molecular metabolism enzyme catalysis glycosylation phytochemistry structural molecular biology free radical biology mithramycin analogues applied microbiology combinatorial biosynthesis gene function chemical biotechnology pharmaceutical chemistry clinical microbiology biomolecules microbial genetics molecular biotechnology biochemical genetics cancer genetics molecular regulation genome biology molecular microbiology bacteriology biotransformation transcription regulation natural product synthesis biological inorganic chemistry pathway engineering redox chemistry protein chemistry pharmaceutical sciences gene regulation metabolic products structure-function enzyme kinetics pathway analysis pharmaceutical biotechnology biosynthetic pathway jadomycin biosynthesis glycosyltransferase genes baeyer-villiger monooxygenase mtmoiv enzymatic total synthesis landomycin biosynthesis mithramycin biosynthetic pathway antitumor drug mithramycin biosynthetic gene cluster biosynthetic studies biological properties late steps key enzyme

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 3504: Mithramycin Analogues Trap the Ews-Fli1 Transcriptional Complex, Evict Etv6, and Disable Oncogenic Condensate Function in Ewing Sarcoma. Cancer Research (2026)

tumor biologyoncogenic agentoncogenescell biology

Nonlinear Mixed-Effects Modeling to Characterize the Pharmacokinetics of a Novel Mithramycin Analogue for Ewing Sarcoma in Mice. Research Square (2026)

biomedical modelingpharmacologymetronomic chemotherapypharmacokineticspharmacotherapysarcomaphysiologically-based pharmacokinetic modeling

Abstract 4360: Development of a Novel Mithramycin Analogue With Improved Pharmacokinetics and Therapeutic Window for Targeted Inhibition of Ews-Fli1 in Ewing Sarcoma. Cancer Research (2025)

pharmacologycancer researchmolecular cancertherapeutic targetscancer treatment

Preclinical Pharmacokinetic Evaluation of Mithramycin and Mithramycin Sa Tryptophan-Conjugated Analog. Pharmaceutics (2025)

medicinepharmacologyantibiotic adjuvantantibioticspharmaceutics

The Position of Indole Methylation Controls the Structure, Dna Binding, and Cellular Functions of Mithramycin Sa‐Trp Analogues. ChemBioChem (2025)

medicinal chemistrybioconjugationbiochemical interactionchemical biologysmall molecule librarymolecular biologybiological chemistrybiochemistry

Contents List. Dalton Transactions (2024)

Xiang LiShengchao ChaiHaolong LiCharles BeasleyOlivia DuletskiKsenia StankevichNavamoney ArulsamyMichael MockNing-Ning ZhangYa-Nan ZhangLi LiZhen-Yu LiYa-Tong LiuYunyun DongYong YanLinlin ZhangYiguang ChenLianghao YuXin TaoLan TangLiangzheng YeYu LiuLu HanHengzheng LiYihan LingGuang ZhuHuile JinWenjian YangJingshen ZhangHui XiongJing LanSongyang YuanMengdi ZhanZiyu TanWenzhe LiJiandong FanAlexander ShindrovYelizaveta MorkhovaJiaxiang LiuYuzhen ZhaoZhe ZhangManni LiWenqi SongWentao LiZongcheng MiaoFarzad FarahmandzadehHoda HekmataraMehdi MolaeiChanreingam LongManabendra RayKyle PearceLouis MorrisThomas RobinsonAndrew JohnsonMary MahonMichael Hill

nuclear chemistrystructural chemistrychemical sciencesorganometallic chemistrybiochemistrycoordination chemistryinorganic chemistry frontierchemistry educationchemical structurechemical measurementgeneral chemistrychemical analysistheoretical chemistrycontents listchemistrymathematical chemistrytransition metal chemistryorganic chemistryinorganic chemistryphilosophy of chemistryroyal societymain group chemistrycheminformaticsleading chemistry community

Highly Diverse Endophytic Fungi From Serra Do Amolar-Pantanal (Brazil) Producing Bioactive Secondary Metabolites Against Phytopathogens. Frontiers in Microbiology (2024)

Bárbara Fanaya MayrhoferJucélia IantasSandriele Aparecida NorilerLarissa V. PonomarevaJon S. ThorsonJürgen RohrKhaled A. ShaabanChirlei Glienke

microbial pathogenesisdiverse endophytic fungienvironmental microbiologyfungusfungal diversityendophyte researchmicrobiologysecondary metabolitesbioactive secondary metabolites

Abstract B150: Targeting Ews-Fli1 With Mithramycin Analogues for Ewing Sarcoma Treatment. Molecular Cancer Therapeutics (2023)

Markos LeggasKumar K NiloyRajesh YetijaramJamie HornYasuda KazutoThomas PrisinzanoJon S ThorsonOleg TsoikovJurgen Rohr

mithramycin analoguestumor targetingmedicinemolecular cancercancer genomicsanti-cancer agentssarcoma treatmentcancer researchsurgical oncologytherapeutic targetssarcomadrug targetingcancer treatmenttumor biologypharmacologyradiation oncologypharmacotherapyoncologymedicinal researchcellular therapy

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicsstructure elucidationcrystal researchcrystal diffraction studystructure determinationstructural chemistryccdc 2157502chemistrydeposited datasetcrystal engineeringchemical structurecrystal structurescrystallography

Paecilins Q and R: Antifungal Chromanones Produced by the Endophytic Fungus Pseudofusicoccum Stromaticum Cmrp4328. Planta Medica (2023)

Jucélia IantasKhaled A. ShaabanDaiani Cristina SaviLarissa V. PonomarevaJon S. ThorsonJürgen RohrChirlei Glienke

plant scienceantifungal chromanonesbotanypharmacology

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Jurgen Rohr

Vice-Chair and Professor

University of Kentucky

Affiliations

College of Pharmacy

Jurgen Rohr is currently serving as a College Of Pharmacy Vice-Chair and Professor at University of Kentucky.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jurgen Rohr

University of Kentucky

Vice-Chair and Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 3504: Mithramycin Analogues Trap the Ews-Fli1 Transcriptional Complex, Evict Etv6, and Disable Oncogenic Condensate Function in Ewing Sarcoma. Cancer Research (2026)

tumor biologyoncogenic agentoncogenescell biology

Nonlinear Mixed-Effects Modeling to Characterize the Pharmacokinetics of a Novel Mithramycin Analogue for Ewing Sarcoma in Mice. Research Square (2026)

biomedical modelingpharmacologymetronomic chemotherapypharmacokineticspharmacotherapysarcomaphysiologically-based pharmacokinetic modeling

Abstract 4360: Development of a Novel Mithramycin Analogue With Improved Pharmacokinetics and Therapeutic Window for Targeted Inhibition of Ews-Fli1 in Ewing Sarcoma. Cancer Research (2025)

pharmacologycancer researchmolecular cancertherapeutic targetscancer treatment

Preclinical Pharmacokinetic Evaluation of Mithramycin and Mithramycin Sa Tryptophan-Conjugated Analog. Pharmaceutics (2025)

medicinepharmacologyantibiotic adjuvantantibioticspharmaceutics

The Position of Indole Methylation Controls the Structure, Dna Binding, and Cellular Functions of Mithramycin Sa‐Trp Analogues. ChemBioChem (2025)

medicinal chemistrybioconjugationbiochemical interactionchemical biologysmall molecule librarymolecular biologybiological chemistrybiochemistry

Contents List. Dalton Transactions (2024)

Highly Diverse Endophytic Fungi From Serra Do Amolar-Pantanal (Brazil) Producing Bioactive Secondary Metabolites Against Phytopathogens. Frontiers in Microbiology (2024)

Bárbara Fanaya MayrhoferJucélia IantasSandriele Aparecida NorilerLarissa V. PonomarevaJon S. ThorsonJürgen RohrKhaled A. ShaabanChirlei Glienke

microbial pathogenesisdiverse endophytic fungienvironmental microbiologyfungusfungal diversityendophyte researchmicrobiologysecondary metabolitesbioactive secondary metabolites

Abstract B150: Targeting Ews-Fli1 With Mithramycin Analogues for Ewing Sarcoma Treatment. Molecular Cancer Therapeutics (2023)

Markos LeggasKumar K NiloyRajesh YetijaramJamie HornYasuda KazutoThomas PrisinzanoJon S ThorsonOleg TsoikovJurgen Rohr

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

Paecilins Q and R: Antifungal Chromanones Produced by the Endophytic Fungus Pseudofusicoccum Stromaticum Cmrp4328. Planta Medica (2023)

Jucélia IantasKhaled A. ShaabanDaiani Cristina SaviLarissa V. PonomarevaJon S. ThorsonJürgen RohrChirlei Glienke

plant scienceantifungal chromanonesbotanypharmacology

1
2
3
4
5
26
10 / page

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University of Kentucky

biochemistry

molecular biology

Ben Shen

Institution

University of Florida

biosynthesis

natural product communication

Craig A. Townsend

Institution

Johns Hopkins University

biochemistry

molecular biology

Shantu Amin

Institution

Pennsylvania State University

cancer letter

polycyclic aromatic hydrocarbon

Shahriar Mobashery

Institution

University of Notre Dame

pharmacology

biochemistry

Courtney Aldrich

Institution

University of Minnesota

medicinal chemistry

pharmacology

Suzanne Walker

Institution

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molecular metabolism

drug resistance analysis

Anthony E. Pegg

Institution

Pennsylvania State University

cancer letter

toxicological mechanism

Charles E. McKenna

Institution

University of Southern California

future medicinal chemistry

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Philip A. Cole

Institution

Johns Hopkins University

molecular biology

biochemistry