Faculty

Institution

Unit

Venue

F. Jon Kull

Rodgers Professor of Chemistry Dean of the Guarini School of Graduate and Advanced Studies

Dartmouth College

Affiliations

Faculty of Arts and Sciences

Department of Chemistry

F. Jon Kull is currently serving as a Chemistry Rodgers Professor of Chemistry Dean of the Guarini School of Graduate and Advanced Studies at Dartmouth College.

Honors

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Experiences

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Education

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F. Jon Kull

Dartmouth College

Rodgers Professor of Chemistry Dean of the Guarini School of Graduate and Advanced Studies

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molecular biology structural biology protein structure protein science structural molecular biology biochemistry biomolecular structure microbial pathogenesis virulence factors neuroscience genetics crystal structures clinical microbiology biological macromolecules molecular cell biology gene expression protein function membrane biology crystallography molecular and cellular biology biological chemistry virology molecular microbiology cellular physiology enzyme inhibition bacteriology cell motility biochemical sciences protein transport viral genetics molecular regulation vibrio cholerae fatty acid regulation mammalian biology cell biomechanics cellular biology virus structure molecular physiology redox biology biomolecular interactions transcription regulation microbial virus motor domain motor proteins neurospora crassa virus research microbial genetics molecular substrates proteinlipid interaction functional modification enzyme catalysis structural genomics virulence gene activator molecular motor proteins metal switch kinesin motor domain strong binding virulence genes avian biology animal science gene structure integrative biology molecular basis bioacoustics biochemical genetics membrane transport kin recognition structural bioinformatics cell cycle host specificity intermediate host structural similarity electron cryo-microscopy kinesin-related motor ncd structural model actin-induced nucleotide release pathogenic bacteria microbiology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Characterization of the Ligand Binding Pocket of the Virulence Regulator Rns, a Member of the Arac/Xyls Family of Transcription Factors. bioRxiv (Cold Spring Harbor Laboratory) (2025)

biological macromoleculesprotein sciencearac/xyls familybiomolecular structuretranscription factorsprotein functiongene regulationmolecular cell biologyvirulence factorstranscription (biology)molecular biologytranscription regulationprotein structuresystems biologygene expressionstructural molecular biologyvirulence regulator rns

Vibrio Cholerae Csra Controls Toxr Levels by Increasing the Stability and Translation of Toxr Mrna. mBio (2024)

Alexandra R. MeyCharles R. MidgettF. Jon KullShelley M. Payne

infectious diseasespathogenic bacteriarna processingantimicrobial resistancemicrobiologypathogensvirulence factorsmolecular biologygene expressionredox biologymicrobial pathogenesis

Structural Insights Into Regulation of Vibrio Virulence Gene Networks. Advances in experimental medicine and biology (2023)

structural insightspathogenic bacteriapathogenesisbiomolecular structuremolecular microbiologymicrobiologymolecular cell biologyvirulence factorsstructural molecular biologymicrobial pathogenesis

An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of Toxt. ACS Medicinal Chemistry Letters (2021)

lipidslipid chemistrybiomoleculesenantioselective synthesispotent inhibitorbiochemistrypharmacologydrug discoverypharmacological researchenzyme inhibition

An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of Toxt. ACS Medicinal Chemistry Letters (2021)

Lauren E. MarkhamJessica D. TolbertF. Jon KullCharles R. MidgettGlenn C. Micalizio

conformational studiesenantioselective synthesispotent inhibitorimmunologymedicinal chemistryclinical chemistrymedicinepharmacologydrug discoveryenzyme inhibitionbiomimetic chemistrystructural biology

Structure of the Master Regulator Rns Reveals an Inhibitor of Enterotoxigenic Escherichia Coli Virulence Regulons. Scientific Reports (2021)

master regulator rnspathogenic bacteriabiomolecular structuremicrobiologytoxinsvirulence factorsmolecular biologybacteriologystructural molecular biologystructural biologymicrobial pathogenesis

A Disulfide Constrains the Toxr Periplasmic Domain Structure, Altering Its Interactions With Toxs and Bile-Salts. Scientific Reports (2020)

lipidsbiological macromoleculesproteinlipid interactionprotein scienceprotein secretionmembrane proteinsbiochemistrybiochemical sciencesbiological chemistryprotein structurestructural molecular biologybiomolecular engineering

Fatty Acid Regulation of Virulence in Vibrio Cholerae: A Structural Analysis of Unbound, Ligand‐Bound, and Dna‐Bound Toxt. The FASEB Journal (2020)

Morgan E. D’AusilioCole MorrielloKristin OsikaBelinda PohAshleigh ProvoostCaitlin SchwarzMaureen SchwarzAnton VolchenkovAllen WuF. Jon Kull

clinical microbiologyinfectious diseasesvirologyparasitologyvirus structuremicrobiologybacteriavirulence factorsfatty acid regulationviral geneticsstructural biologygeneticsmicrobial pathogenesis

Publisher Correction: A Disulfide Constrains the Toxr Periplasmic Domain Structure, Altering Its Interactions With Toxs and Bile-Salts. Scientific Reports (2020)

Charles R. MidgettRachel A. SwindellMaria PellegriniF. Jon Kull

scientific communicationpublisher correctionmaterials science

Structural Analysis of the Master Regulator Rns Reveals a Small Molecule Inhibitor of Enterotoxigenic Escherichia Coli Virulence. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Charles R MidgettKacey Marie TalbotJessica L. DayGeorge P MunsonF Jon Kull

clinical microbiologyinfectious diseasesvirologymicrobial viruspathogenic bacteriapathogen transmissionmolecular microbiologymaster regulatormicrobiologypathogensmolecular biologystructural biologymicrobial pathogenesis

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F. Jon Kull

Rodgers Professor of Chemistry Dean of the Guarini School of Graduate and Advanced Studies

Dartmouth College

Affiliations

Faculty of Arts and Sciences

Department of Chemistry

F. Jon Kull is currently serving as a Chemistry Rodgers Professor of Chemistry Dean of the Guarini School of Graduate and Advanced Studies at Dartmouth College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

F. Jon Kull

Dartmouth College

Rodgers Professor of Chemistry Dean of the Guarini School of Graduate and Advanced Studies

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Characterization of the Ligand Binding Pocket of the Virulence Regulator Rns, a Member of the Arac/Xyls Family of Transcription Factors. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Vibrio Cholerae Csra Controls Toxr Levels by Increasing the Stability and Translation of Toxr Mrna. mBio (2024)

Alexandra R. MeyCharles R. MidgettF. Jon KullShelley M. Payne

infectious diseasespathogenic bacteriarna processingantimicrobial resistancemicrobiologypathogensvirulence factorsmolecular biologygene expressionredox biologymicrobial pathogenesis

Structural Insights Into Regulation of Vibrio Virulence Gene Networks. Advances in experimental medicine and biology (2023)

structural insightspathogenic bacteriapathogenesisbiomolecular structuremolecular microbiologymicrobiologymolecular cell biologyvirulence factorsstructural molecular biologymicrobial pathogenesis

An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of Toxt. ACS Medicinal Chemistry Letters (2021)

lipidslipid chemistrybiomoleculesenantioselective synthesispotent inhibitorbiochemistrypharmacologydrug discoverypharmacological researchenzyme inhibition

An Enantiodefined Conformationally Constrained Fatty Acid Mimetic and Potent Inhibitor of Toxt. ACS Medicinal Chemistry Letters (2021)

Lauren E. MarkhamJessica D. TolbertF. Jon KullCharles R. MidgettGlenn C. Micalizio

Structure of the Master Regulator Rns Reveals an Inhibitor of Enterotoxigenic Escherichia Coli Virulence Regulons. Scientific Reports (2021)

master regulator rnspathogenic bacteriabiomolecular structuremicrobiologytoxinsvirulence factorsmolecular biologybacteriologystructural molecular biologystructural biologymicrobial pathogenesis

A Disulfide Constrains the Toxr Periplasmic Domain Structure, Altering Its Interactions With Toxs and Bile-Salts. Scientific Reports (2020)

Fatty Acid Regulation of Virulence in Vibrio Cholerae: A Structural Analysis of Unbound, Ligand‐Bound, and Dna‐Bound Toxt. The FASEB Journal (2020)

Morgan E. D’AusilioCole MorrielloKristin OsikaBelinda PohAshleigh ProvoostCaitlin SchwarzMaureen SchwarzAnton VolchenkovAllen WuF. Jon Kull

clinical microbiologyinfectious diseasesvirologyparasitologyvirus structuremicrobiologybacteriavirulence factorsfatty acid regulationviral geneticsstructural biologygeneticsmicrobial pathogenesis

Publisher Correction: A Disulfide Constrains the Toxr Periplasmic Domain Structure, Altering Its Interactions With Toxs and Bile-Salts. Scientific Reports (2020)

Charles R. MidgettRachel A. SwindellMaria PellegriniF. Jon Kull

scientific communicationpublisher correctionmaterials science

Structural Analysis of the Master Regulator Rns Reveals a Small Molecule Inhibitor of Enterotoxigenic Escherichia Coli Virulence. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Charles R MidgettKacey Marie TalbotJessica L. DayGeorge P MunsonF Jon Kull

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