Faculty

Institution

Unit

Venue

Zygmunt Derewenda

Professor Molecular Physiology and Biological Physics

University of Virginia

Affiliations

School of Medicine

Department of Molecular Physiology and Biological Physics

Zygmunt Derewenda is currently serving as a Molecular Physiology And Biological Physics Professor Molecular Physiology and Biological Physics at University of Virginia.

Honors

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Experiences

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Education

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Zygmunt Derewenda

University of Virginia

Professor Molecular Physiology and Biological Physics

You can click a keyword to filter the displayed items

molecular biology biochemistry biomolecular structure protein structure structural molecular biology structural biology protein science protein x-ray crystallography crystal structures enzymes biological macromolecules crystallography molecular structure biological chemistry protein function molecular cell biology biomolecular engineering signal transduction biomolecules chemical biology enzyme inhibition microbiology biophysical chemistry protein assembly protein chemistry lipids cellular biochemistry enzyme catalysis structure-function enzyme kinetics x-ray crystallography biochemical sciences molecular physiology crystal research lipid chemistry g protein-coupled receptor signaling pathways cellular physiology biocatalysis hydrogen bond molecular regulation biomolecular interactions structural bioinformatics protein phosphorylation fungal genetics virus research enzymatic modification proteinlipid interaction molecular microbiology crystal formation escherichia coli cellular enzymology chemical bond enzyme specificity insulin signaling smooth muscle pdz tandem fungal physiology lipid science heme homeostasis molecular neurobiology multi-protein assembly altmetric attention score protein biosynthesis cellular neurobiology protein crystallization pdz domains gtp hydrolysis bacillus subtilis pdz2 domain conformational entropy molecular model refinement rgs-like domain molecular replacement method serine protease triad triacylglycerol lipase catalytic centre

Notable Scholarly Works

Notable Federal Grants

Collaborators

How Protein Kinase Inhibitors Bind to the Hinge Region of the Target Protein.. Structural Dynamics (2025)

signaling pathwaysbiomolecular interactionsenzyme inhibitionprotein kinase inhibitorsprotein functiontarget proteincell signalingprotein phosphorylationreceptor tyrosine kinasestherapeutic targetsdrug discoverymolecular biologyhinge regionsignal transductionprotein sciencecellular biochemistrybiochemistrycell biology

The Occurrence of Trpcd1-H…O=Cbackbone Hydrogen Bonds in Proteins. Structural Dynamics (2025)

MIchal SczygielUrszula DerewendaSteve ScheinerWladek MinorZygmunt Derewenda

trp residuesprotein structurebiochemistrybiophysical chemistrydata miningbiomolecular structurestructural biologyprotein scienceprotein foldingprotein chemistryprotein assemblytryptophan residueprotein designprotein engineeringchemical bondmolecular structurebiomolecular engineeringstructural molecular biologyhydrogen bond

A Structural Role for Tryptophan in Proteins, and the Ubiquitous Trp C δ1 —H...O=C (Backbone) Hydrogen Bond. Acta Crystallographica Section D Structural Biology (2024)

Michal SzczygielUrszula DerewendaSteve ScheinerWladek MinorZygmunt S. Derewenda

protein chemistrychemical bondprotein structureindole ringhydrogen bondsbiomolecular structuremolecular biologystructural molecular biologybiochemistrystructural biologyprotein scienceprotein engineeringhydrogen bondprotein folding

Differing Effects of Nonlinearity Around the Proton Acceptor on Ch··O and Nh··O H-Bond Strength Within Proteins. The Journal of Physical Chemistry B (2024)

Steve ScheinerZygmunt S. Derewenda

biophysical chemistrybiophysicscomputational chemistrytheoretical chemistrychemical bondmolecular modellingmolecular structurequantum chemistryamide groupproton donorsproton acceptorbiomolecular structureproton transferhydrogen bondbiochemistry

C-H Groups as Donors in Hydrogen Bonds: A Historical Overview and Occurrence in Proteins and Nucleic Acids. International Journal of Molecular Sciences (2023)

Zygmunt Stanislaw Derewenda

biophysicshistorical overviewmolecular sciencemolecular biologystructural biologyprotein sciencec-h groupsbiochemistry

C—H...O Bonds Involving Trp Sidechain in Protein Structures. Acta Crystallographica Section A Foundations and Advances (2023)

Michal SzczygielWladek MinorZygmunt Derewenda

biophysicstrp sidechainbiomolecular engineeringstructural biologyprotein sciencex-ray crystallographycrystallography

P90Rsk2, a New Mlck Mediates Contractility in Myosin Light Chain Kinase Null Smooth Muscle. Frontiers in Physiology (2023)

Jaspreet KalraMykhaylo ArtamonovHua WangAaron FrankeZaneta MarkowskaLi JinZygmunt S. DerewendaRamon J. AyonAvril Somlyo

physiologyphysiological researchhuman physiologyneurophysiologyprotein scienceneurosciencemolecular physiologymyosin light chain

Rosalind E. Franklin and Dna: Facts and Myths. Acta Crystallographica Section A Foundations and Advances (2023)

Zygmunt S. Derewenda

geneticsmolecular biologydna analysisx-ray crystallographycrystallographybiochemistry

Aurora a Phosphorylates Ndel1 to Reduce the Levels of Mad1 and Numa at Spindle Poles. Molecular Biology of the Cell (2022)

Paweł Ł. JanczykEliza ŻyłkiewiczHenry De HoyosThomas WestDaniel R. MatsonWon-Chan ChoiHeather M. Raimer YoungZygmunt S. DerewendaP. Todd Stukenberg

gene expressionphosphorescencecell signalinggeneticsprotein phosphorylationmolecular cell biologyspindle polesmolecular biologystructural biologybiochemistry

Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the Discovery of Dna's Double Helix. by Howard Markel. W. W. Norton Co., 2021. Hardback, Pp. 608. Isbn 978-1324002239. Price Usd 30.00.. Acta Crystallographica Section D Structural Biology (2022)

Zygmunt S. Derewenda

genomicsgeneticsmolecular biologymolecular geneticsdna analysisbiomolecular structurebiochemistrynucleic acids

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Zygmunt Derewenda

Professor Molecular Physiology and Biological Physics

University of Virginia

Affiliations

School of Medicine

Department of Molecular Physiology and Biological Physics

Zygmunt Derewenda is currently serving as a Molecular Physiology And Biological Physics Professor Molecular Physiology and Biological Physics at University of Virginia.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Zygmunt Derewenda

University of Virginia

Professor Molecular Physiology and Biological Physics

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

How Protein Kinase Inhibitors Bind to the Hinge Region of the Target Protein.. Structural Dynamics (2025)

The Occurrence of Trpcd1-H…O=Cbackbone Hydrogen Bonds in Proteins. Structural Dynamics (2025)

MIchal SczygielUrszula DerewendaSteve ScheinerWladek MinorZygmunt Derewenda

A Structural Role for Tryptophan in Proteins, and the Ubiquitous Trp C δ1 —H...O=C (Backbone) Hydrogen Bond. Acta Crystallographica Section D Structural Biology (2024)

Michal SzczygielUrszula DerewendaSteve ScheinerWladek MinorZygmunt S. Derewenda

Differing Effects of Nonlinearity Around the Proton Acceptor on Ch··O and Nh··O H-Bond Strength Within Proteins. The Journal of Physical Chemistry B (2024)

Steve ScheinerZygmunt S. Derewenda

C-H Groups as Donors in Hydrogen Bonds: A Historical Overview and Occurrence in Proteins and Nucleic Acids. International Journal of Molecular Sciences (2023)

Zygmunt Stanislaw Derewenda

biophysicshistorical overviewmolecular sciencemolecular biologystructural biologyprotein sciencec-h groupsbiochemistry

C—H...O Bonds Involving Trp Sidechain in Protein Structures. Acta Crystallographica Section A Foundations and Advances (2023)

Michal SzczygielWladek MinorZygmunt Derewenda

biophysicstrp sidechainbiomolecular engineeringstructural biologyprotein sciencex-ray crystallographycrystallography

P90Rsk2, a New Mlck Mediates Contractility in Myosin Light Chain Kinase Null Smooth Muscle. Frontiers in Physiology (2023)

Jaspreet KalraMykhaylo ArtamonovHua WangAaron FrankeZaneta MarkowskaLi JinZygmunt S. DerewendaRamon J. AyonAvril Somlyo

physiologyphysiological researchhuman physiologyneurophysiologyprotein scienceneurosciencemolecular physiologymyosin light chain

Rosalind E. Franklin and Dna: Facts and Myths. Acta Crystallographica Section A Foundations and Advances (2023)

Zygmunt S. Derewenda

geneticsmolecular biologydna analysisx-ray crystallographycrystallographybiochemistry

Aurora a Phosphorylates Ndel1 to Reduce the Levels of Mad1 and Numa at Spindle Poles. Molecular Biology of the Cell (2022)

Paweł Ł. JanczykEliza ŻyłkiewiczHenry De HoyosThomas WestDaniel R. MatsonWon-Chan ChoiHeather M. Raimer YoungZygmunt S. DerewendaP. Todd Stukenberg

gene expressionphosphorescencecell signalinggeneticsprotein phosphorylationmolecular cell biologyspindle polesmolecular biologystructural biologybiochemistry

Zygmunt S. Derewenda

genomicsgeneticsmolecular biologymolecular geneticsdna analysisbiomolecular structurebiochemistrynucleic acids

1
2
3
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5
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10 / page

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protein misfolding

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Robert Nakamoto

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biochemistry

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protein x-ray crystallography

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