Faculty

Institution

Unit

Venue

John Macmillan

Vice Chancellor for Research Professor

University of California, Santa Cruz

Affiliations

Social Sciences

Global and Community Health

Physical & Biological Sciences

Microbiology & Environmental Toxicology

John Macmillan is currently serving as a Global And Community Health Vice Chancellor for Research Professor at University of California, Santa Cruz.

Honors

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Experiences

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Education

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John Macmillan

University of California, Santa Cruz

Vice Chancellor for Research Professor

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pharmacology chemistry molecular biology drug discovery organic chemistry natural products medicinal chemistry oncology natural product research organic synthesis cancer biology microbiology cancer treatment marine biology respiratory medicine protein science chemical sciences marine chemistry enzyme inhibition molecular physiology natural product synthesis phytochemistry structural biology clinical chemistry heterocyclic phycology molecular regulation colorectal cancer clinical microbiology scientific data molecular cell biology biological chemistry biochemical sciences marine drug cellular physiology reproducible research pharmaceutical chemistry drug targeting pathway analysis functional signature ontology total synthesis marine actinomycete structural molecular biology personalized treatments protein transport disease transmission retina medical microbiology host-microbe interactions viral pathogenesis pathogen transmission biomolecular interactions molecular substrates biological inorganic chemistry transcription regulation hypoxia (medicine) mechanisms of action target identification pharmaceutical biotechnology pharmacogenomics mutagenesis probiotics cell regulation nuclear export inhibition covalent conjugation bacterial infection pas-b domain serotonin neurotransmitter enteric pathogens mechanistic roles novel chemical ligands stereoselective inhibition clathrin-mediated endocytosis natural product inhibitor ammosamide analogs precursor-directed generation marine biotechnology bioprospecting lead identification bioorganic chemistry systems biology marine microbiology

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Hormad1 is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress. (2023)

Brandt A. NicholsNathaniel W. OswaldElizabeth A. McMillanKathleen McGlynnJingsheng YanMin S. KimJanapriya SahaPrema L. MallipeddiSydnie A. LaDukePamela A. VillalobosJaime Rodriguez-CanalesIgnacio I. WistubaBruce A. PosnerAnthony J. DavisJohn D. MinnaJohn B. MacMillanAngelique W. Whitehurst

pharmacologythoracic oncologyprognosistumor biologycancer researchoxidative stresshealth sciencesprognostic biomarkersrespiratory medicinemedicinal researchcancer risknegative prognostic indicatorcancer carecancer biologylung adenocarcinomabiostatisticsprognostic evaluationmolecular medicinefree radical biologyoncology

Modulation of in Vitro Sars-Cov-2 Infection by Stephania Tetrandra and Its Alkaloid Constituents. Journal of Natural Products (2023)

Aswad KhadilkarZoie L. BunchJessica WagonerVandana RavindranJessica M. OdaWarren S. VidarTrevor N. ClarkPreston K. ManwillDaniel A. ToddSarah A. BarrLauren K. OlingerSusan L. FinkWendy K. StrangmanRoger G. LiningtonJohn B. MacMillanNadja B. CechStephen J. Polyak

alkaloid constituentsnatural product researchnatural product biosynthesisclinical mycologynatural productsactive ingredientmedicinal chemistrymicrobiologysars-cov-2natural product synthesispharmacologymedicinetraditional medicinescovid-19phytochemical analysismedical mycology

Supplementary Methods and Materials From Hormad1 is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress. (2023)

lung adenocarcinomaradiation oncologynegative prognostic indicatortumor biologyrespiratory medicineoxidation resistancefree radical biologydrug resistancecancer researchpharmacologyoxidative stressthoracic oncologycancer treatmentsupplementary methodshealth sciencesoncologycancer biology

Antibiotic Natural Product Hunanamycin a: Lead Identification Towards Anti-Salmonella Agents. European Journal of Medicinal Chemistry (2022)

Rahul D. ShingareJohn B. MacMillanD. Srinivasa Reddy

public healthanti-salmonella agentslead identificationantibiotic natural productmedicinal chemistrypharmacologydrug discoveryhealth sciences

Biomimetic Total Synthesis and Investigation of the Non‐Enzymatic Chemistry of Oxazinin A. Angewandte Chemie International Edition (2022)

Victor AniebokRahul D. ShingareHsiau Wei‐LeeTimothy C. JohnstoneJohn B. MacMillan

biomimetic total synthesisnon-enzymatic chemistryorganic synthesisbiochemistry

Boron Nmr as a Method to Screen Natural Product Libraries for B-Containing Compounds. Organic Letters (2022)

Jocelyn M. MachoRiley M. BlueHsiau-Wei LeeJohn B. MacMillan

boron nmrb-containing compoundschemistrynatural product libraries

High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling. Proceedings of the National Academy of Sciences (2022)

Suzie K. HightTrevor N. ClarkKenji L. KuritaElizabeth A. McMillanWalter BrayAnam F. ShaikhAswad KhadilkarF. P. Jake HaecklFausto Carnevale-NetoScott LaAkshar LohithRachel M. VadenJeon LeeShuguang WeiR. Scott LokeyMichael A. WhiteRoger G. LiningtonJohn B. MacMillan

integrated activity profilingomics technologieshigh-throughput functional annotationscience and technology studiesbiomolecular engineering

Nonenzymatic Reactions in Natural Product Formation. Chemical Reviews (2022)

Leah M. BouthilletteVictor AniebokDominic A. ColosimoDavid BrumleyJohn B. MacMillan

chemical sciencesnonenzymatic reactionschemical engineeringnatural product formationchemistrypharmacologyorganic chemistry

11 B and 1 H– 11 B Hmbc Nmr as a Tool for Identification of a Boron-Containing Nucleoside Dimer. Journal of Natural Products (2022)

Riley M. BlueJocelyn M. MachoHsiau-Wei LeeJohn B. MacMillan

molecular characterizationnatural product researchnatural productsboron-containing nucleoside dimernanotechnologyanalytical chemistrybiochemistrybiologymolecular biologyorganic chemistrynuclear magnetic resonance

A Method for Campus-Wide Sars-Cov-2 Surveillance at a Large Public University. PLoS ONE (2021)

Terren ChangJolene M. DraperAnouk Van den BoutEllen KephartHannah Maul-NewbyYvonne VasquezJason WoodburySavanna RandiMartina PedersenMaeve NaveScott LaNatalie GallagherMolly M. McCabeNamrita DhillonIsabel BjorkMichael LuttrellFrank DangJohn B. MacMillanRalph GreenElizabeth MillerAuston M. KilpatrickOlena VaskeMichael D. StoneJeremy R. Sanford

public healthhuman monitoringepidemiologyvirus epidemiologylarge public universitydisease surveillancerespiratory medicinesars-cov-2global healthsecurity studiescovid-19

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John Macmillan

Vice Chancellor for Research Professor

University of California, Santa Cruz

Affiliations

Social Sciences

Global and Community Health

Physical & Biological Sciences

Microbiology & Environmental Toxicology

John Macmillan is currently serving as a Global And Community Health Vice Chancellor for Research Professor at University of California, Santa Cruz.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John Macmillan

University of California, Santa Cruz

Vice Chancellor for Research Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Hormad1 is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress. (2023)

Modulation of in Vitro Sars-Cov-2 Infection by Stephania Tetrandra and Its Alkaloid Constituents. Journal of Natural Products (2023)

Supplementary Methods and Materials From Hormad1 is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress. (2023)

Antibiotic Natural Product Hunanamycin a: Lead Identification Towards Anti-Salmonella Agents. European Journal of Medicinal Chemistry (2022)

Rahul D. ShingareJohn B. MacMillanD. Srinivasa Reddy

public healthanti-salmonella agentslead identificationantibiotic natural productmedicinal chemistrypharmacologydrug discoveryhealth sciences

Biomimetic Total Synthesis and Investigation of the Non‐Enzymatic Chemistry of Oxazinin A. Angewandte Chemie International Edition (2022)

Victor AniebokRahul D. ShingareHsiau Wei‐LeeTimothy C. JohnstoneJohn B. MacMillan

biomimetic total synthesisnon-enzymatic chemistryorganic synthesisbiochemistry

Boron Nmr as a Method to Screen Natural Product Libraries for B-Containing Compounds. Organic Letters (2022)

Jocelyn M. MachoRiley M. BlueHsiau-Wei LeeJohn B. MacMillan

boron nmrb-containing compoundschemistrynatural product libraries

High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling. Proceedings of the National Academy of Sciences (2022)

integrated activity profilingomics technologieshigh-throughput functional annotationscience and technology studiesbiomolecular engineering

Nonenzymatic Reactions in Natural Product Formation. Chemical Reviews (2022)

Leah M. BouthilletteVictor AniebokDominic A. ColosimoDavid BrumleyJohn B. MacMillan

chemical sciencesnonenzymatic reactionschemical engineeringnatural product formationchemistrypharmacologyorganic chemistry

11 B and 1 H– 11 B Hmbc Nmr as a Tool for Identification of a Boron-Containing Nucleoside Dimer. Journal of Natural Products (2022)

Riley M. BlueJocelyn M. MachoHsiau-Wei LeeJohn B. MacMillan

A Method for Campus-Wide Sars-Cov-2 Surveillance at a Large Public University. PLoS ONE (2021)

public healthhuman monitoringepidemiologyvirus epidemiologylarge public universitydisease surveillancerespiratory medicinesars-cov-2global healthsecurity studiescovid-19

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