Faculty

Institution

Unit

Venue

John C. Morris, MD

Harvey A and Dorismae Hacker Friedman Distinguished Professor of Neurology Professor of Pathology and Immunology Professor of Physical Therapy and Professor of Occupational Therapy

Washington University in St. Louis

Affiliations

School of Medicine

Program in Occupational Therapy

John C. Morris, MD, is the Harvey A and Dorismae Hacker Friedman Distinguished Professor of Neurology, as well as a Professor of Pathology & Immunology, Physical Therapy, and Occupational Therapy at Washington University in St. Louis. A leading neuroscientist, his research integrates neuroimaging, fluid biomarkers, genetics, and cognitive neuroscience to delineate the biological staging, temporal sequencing, and heterogeneity of Alzheimer’s disease. His recent breakthroughs include a highly accurate blood test validated against cerebrospinal fluid, multimodal modeling of ATN biomarkers, and Gene-SGAN-based disease subtyping. His extensive international collaborations span Europe, Asia, and the Americas.

Honors

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John C. Morris, MD

Washington University in St. Louis

Harvey A and Dorismae Hacker Friedman Distinguished Professor of Neurology Professor of Pathology and Immunology Professor of Physical Therapy and Professor of Occupational Therapy

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alzheimer's disease neuroscience neurology dementia neurodegenerative diseases health sciences cognitive impairment genetics cognitive neuroscience neuroimaging neuroscience of aging geriatrics oncology medicinal research aging-associated diseases alzheimer disease molecular neurodegeneration brain imaging clinical neurology thyroid cerebrospinal fluid cancer treatment geriatric neurology clinical neuroscience geriatric medicine autosomal dominant alzheimer degenerative disease preclinical alzheimer thyroid disease neurorehabilitation brain function cancer care neuroimaging biomarkers experimental gerontology biomedical imaging preclinical alzheimer disease later adulthood vascular biology clinical gerontology older adults brain pathology disease progression oncogenes alzheimer type cognitive decline cancer imaging endocrine oncology neuropsychiatry brain health neuroinflammation leukemia cancer biology driver behavior cancer discovery brain science memory loss tumor targeting neuropsychological rehabilitation medical genetics clinical evidence aging cell mild cognitive impairment memory assessment vascular dementia degenerative pathology clinical immunology sodium iodide symporter genome-wide association studies cerebrospinal fluid biomarkers alzheimer network biological psychiatry senile dementia mild dementia thyroid cancer pilot study uniform data set alzheimer’s disease corticobasal degeneration

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analyzing Heterogeneity in Alzheimer Disease Using Multimodal Normative Modeling on Imaging‐Based Atn Biomarkers. Alzheimer s & Dementia (2025)

Sayantan KumarTom EarnestBraden YangDeydeep KothapalliAndrew J AschenbrennerJason HassenstabChengie XiongBeau AncesJohn MorrisTammie L S BenzingerBrian A GordonPhilip PayneAristeidis Sotiras

biomedical data analysisbrain imagingmultimodal normative modelingevidence-based medicinealzheimer's diseasealzheimer diseaseneuroscienceimaging-based atn biomarkersnormative analysisimage analysishealth sciencesneurologyneuroimagingbioimage analysis

15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in Dian. medRxiv (2024)

Alisha J. DanielsEric McDadeJorge J. Llibre-GuerraChengjie XiongRichard J. PerrinLaura IbanezCharlene Supnet-BellCarlos CruchagaAlison GoateAlan E. RentonTammie L.S. BenzingerBrian A. GordonJason HassenstabCeleste KarchBrent PoppAllan LeveyJohn MorrisVirginia BucklesRicardo F. AllegriPatricio ChremSarah B. BermanJasmeer P. ChhatwalMartin R. FarlowNick C. FoxGregory S. DayTakeshi IkeuchiMathias JuckerJae-Hong LeeJohannes LevinFrancisco LoperaLeonel TakadaAna Luisa SosaRalph MartinsHiroshi MoriJames M. NobleStephen SallowayEdward HueyPedro Rosa-NetoRaquel Sánchez-VallePeter R. SchofieldJee Hoon RohRandall J. Bateman

biochemistrygeneticsbiochemical measures

A Comprehensive Head-To-Head Comparison of Key Plasma Phosphorylated Tau 217 Biomarker Tests. medRxiv (Cold Spring Harbor Laboratory) (2024)

Noëlle WarmenhovenGemma SalvadóShorena JanelidzeNiklas Mattsson-CarlgrenDivya BaliAnna Orduña DoladoHartmuth KolbGallen Triana-BaltzerNicolas R BarthélemySuzanne E SchindlerAndrew J AschenbrennerCyrus A RajiTammie L S BenzingerJohn C MorrisLaura IbanezJigyasha TimsinaCarlos CruchagaRandall J BatemanNicholas AshtonBurak ArslanHenrik ZetterbergKaj BlennowAlexa Pichet BinetteOskar Hansson

epidemiologyhematologymolecular diagnosticsstrokemethodology comparisonplasma diagnosticslaboratory medicinebenchmark studiesrespiratory medicinepublic healthneurologybiomarker testsbiomarkerscomprehensive head-to-head comparison

Advances in Blood Biomarkers for Alzheimer Disease ( Ad ): A Review. The Kaohsiung Journal of Medical Sciences (2024)

Araya Dimtsu AssfawSuzanne E SchindlerJohn C Morris

biomarker targetmedicinecognitive impairmentalzheimer diseaseneurodegenerative diseasesalzheimer's diseasebiomarker discoveryblood biomarkersbiomarker (medicine)neuroimaging biomarkersprognostic biomarkersneurologybiomarkers

Affective Response to Exercise and Physical Activity Engagement: Preliminary Results. Alzheimer s & Dementia (2024)

Marta StojanovicJohn C. MorrisBeau AncesDenise M Head

alzheimer's diseasedementiaaffective responseexercise sciencephysical activityphysical activity engagementpsychology

A Genetic and Proteomic Comparison of Key Ad Biomarkers Across Tissues. Alzheimer s & Dementia (2024)

Thomas W. MarshDaniel WesternJigyasha TimsinaPriyanka GorijalaChengran YangPau PastorMenghan LiuJohn C. MorrisRandall J. BatemanSuzanne E. SchindlerYun Ju SungCarlos Cruchaga

key ad biomarkersproteome researchgenetic epidemiologyalzheimer's diseaseneurodegenerative diseasesneuroscience of agingbiomarker discoveryaging-associated diseasesneurochemical biomarkersneurosciencemolecular neurodegenerationcsf levelsneurologyclinical proteomicscsf protein levelsbiomarkers

A Highly Accurate Blood Test for Alzheimer’s Disease Pathology Has Performance Equivalent or Superior to Clinically Used Csf Tests. Alzheimer s & Dementia (2024)

Gemma SalvadóNicolas R. BarthélemySuzanne E. SchindlerYingxin HeShorena JanelidzeLyduine E. CollijBenjamin A. SaefRachel L. HensonCharles D. ChenBrian A. GordonYan LiRenaud La JoieTammie L.S. BenzingerJohn C. MorrisNiklas Mattsson‐CarlgrenSebastian PalmqvistRik OssenkoppeleGil D. RabinoviciErik StomrudRandall J. BatemanOskar Hansson

clinical pathologymedicinecognitive impairmentalzheimer's diseaseneurodegenerative diseasesdementiadisease pathologydiagnostic tests

Alzheimer’s Disease Genetic Risk and Changes in Brain Atrophy and White Matter Hyperintensities in Cognitively Unimpaired Adults. Brain Communications (2024)

Anja SoldanJiangxia WangCorinne PettigrewChristos DavatzikosGuray ErusTimothy J HohmanLogan DumitrescuMurat BilgelSusan M ResnickLeonardo A Rivera-RiveraRebecca LanghoughSterling C JohnsonTammie BenzingerJohn C MorrisSimon M LawsJurgen FrippColin L MastersMarilyn S Albert

neurodegenerative diseasesbrain atrophygeneticswhite matter hyperintensities

A Multiple Cohort Study Exploring the Influence of Partial Volume Correction on Age and Sex Effects on Tau Pet Imaging. Alzheimer s & Dementia (2024)

Diana A HobbsShaney FloresSarah J. KeefeJohn C. MorrisTammie L.S. BenzingerBrian A. Gordon

cognitive impairmentalzheimer's diseaseneurodegenerative diseasesdementiacohort studiesmultiple cohort studysex effectsneurosciencemedical imagingpartial volume correction

AMYLOIDPETNET: Classification of Amyloid Positivity in Brain Pet Imaging Using End-To-End Deep Learning. Radiology (2024)

Shuyang FanMaria Rosana PonisioPan XiaoSung Min HaSatrajit ChakrabartyJohn J LeeShaney FloresPamela LaMontagneBrian GordonCyrus A RajiDaniel S MarcusArash NazeriBeau M AncesRandall J BatemanJohn C MorrisTammie L S BenzingerAristeidis Sotiras

biomedical imagingbrain imagingradiographic imagingmedical image computingend-to-end deep learningamyloid positivityneurosciencemedical imagingbrain petradiologyimage analysisneuroimagingdeep learning

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John C. Morris, MD

Harvey A and Dorismae Hacker Friedman Distinguished Professor of Neurology Professor of Pathology and Immunology Professor of Physical Therapy and Professor of Occupational Therapy

Washington University in St. Louis

Affiliations

School of Medicine

Program in Occupational Therapy

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

John C. Morris, MD

Washington University in St. Louis

Harvey A and Dorismae Hacker Friedman Distinguished Professor of Neurology Professor of Pathology and Immunology Professor of Physical Therapy and Professor of Occupational Therapy

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Analyzing Heterogeneity in Alzheimer Disease Using Multimodal Normative Modeling on Imaging‐Based Atn Biomarkers. Alzheimer s & Dementia (2025)

Sayantan KumarTom EarnestBraden YangDeydeep KothapalliAndrew J AschenbrennerJason HassenstabChengie XiongBeau AncesJohn MorrisTammie L S BenzingerBrian A GordonPhilip PayneAristeidis Sotiras

15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in Dian. medRxiv (2024)

biochemistrygeneticsbiochemical measures

A Comprehensive Head-To-Head Comparison of Key Plasma Phosphorylated Tau 217 Biomarker Tests. medRxiv (Cold Spring Harbor Laboratory) (2024)

Advances in Blood Biomarkers for Alzheimer Disease ( Ad ): A Review. The Kaohsiung Journal of Medical Sciences (2024)

Araya Dimtsu AssfawSuzanne E SchindlerJohn C Morris

Affective Response to Exercise and Physical Activity Engagement: Preliminary Results. Alzheimer s & Dementia (2024)

Marta StojanovicJohn C. MorrisBeau AncesDenise M Head

alzheimer's diseasedementiaaffective responseexercise sciencephysical activityphysical activity engagementpsychology

A Genetic and Proteomic Comparison of Key Ad Biomarkers Across Tissues. Alzheimer s & Dementia (2024)

Thomas W. MarshDaniel WesternJigyasha TimsinaPriyanka GorijalaChengran YangPau PastorMenghan LiuJohn C. MorrisRandall J. BatemanSuzanne E. SchindlerYun Ju SungCarlos Cruchaga

A Highly Accurate Blood Test for Alzheimer’s Disease Pathology Has Performance Equivalent or Superior to Clinically Used Csf Tests. Alzheimer s & Dementia (2024)

clinical pathologymedicinecognitive impairmentalzheimer's diseaseneurodegenerative diseasesdementiadisease pathologydiagnostic tests

Alzheimer’s Disease Genetic Risk and Changes in Brain Atrophy and White Matter Hyperintensities in Cognitively Unimpaired Adults. Brain Communications (2024)

neurodegenerative diseasesbrain atrophygeneticswhite matter hyperintensities

A Multiple Cohort Study Exploring the Influence of Partial Volume Correction on Age and Sex Effects on Tau Pet Imaging. Alzheimer s & Dementia (2024)

Diana A HobbsShaney FloresSarah J. KeefeJohn C. MorrisTammie L.S. BenzingerBrian A. Gordon

cognitive impairmentalzheimer's diseaseneurodegenerative diseasesdementiacohort studiesmultiple cohort studysex effectsneurosciencemedical imagingpartial volume correction

AMYLOIDPETNET: Classification of Amyloid Positivity in Brain Pet Imaging Using End-To-End Deep Learning. Radiology (2024)

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