Faculty

Institution

Unit

Venue

Ralph H. Hruban

Professor of Pathology Professor of Oncology

Johns Hopkins University

Affiliations

School of Medicine

Pathology

Ralph H. Hruban is a Professor of Pathology and Oncology at Johns Hopkins University, where he directs the Sol Goldman Pancreatic Cancer Research Center and the Department of Pathology. He earned his medical degree from Johns Hopkins (1985) and completed fellowships at Memorial Sloan Kettering. His research focuses on pancreatic ductal adenocarcinoma precursors, including 3D genomic mapping of pancreatic precancers and high-resolution 3D printing of ductal microanatomy, with recent publications in Nature and JAMA Oncology. He has led international collaborations across North America, Europe, and Asia.

Honors

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Ralph H. Hruban

Johns Hopkins University

Professor of Pathology Professor of Oncology

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oncology cancer research cancer biology pancreatic cancer genetics pathology tumor biology cancer genetics medicine health sciences surgical oncology cancer genomics hepatology medicinal research molecular cancer cancer care surgical pathology hematology gastroenterology clinical pathology genomics gene expression oncogenes cancer imaging respiratory medicine histopathology cancer treatment gastrointestinal oncology gastrointestinal surgery digestive diseases computed tomography genome biology genitourinary cancers molecular pathology general surgery vascular biology liver cancer abdominal imaging molecular diagnostics thoracic oncology human pathology cancer management pancreatic ductal adenocarcinoma cancer cells cancer risk clinical gastroenterology general pathology pancreatic surgery cancer detection radiation therapy pancreatic adenocarcinoma ct scan clinical surgery cytogenetics familial pancreatic cancer surgical care tumor targeting pancreatic intraepithelial neoplasia endocrine oncology medical genetics veterinary pathology hematological malignancies radiomics veterinary surgery pancreatic cysts pancreatic carcinoma high-risk individuals pancreatic neuroendocrine tumors pancreatic ductal adenocarcinomas somatic mutations periampullary adenocarcinoma mucinous cystic neoplasms pancreatic neoplasms aberrant methylation inflation-fixed lungs long-term survival anatomical pathology

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

1153 a Comparative Evaluation of Fibrosis Among Patients With Recurrent Acute and Chronic Pancreatitis Undergoing Total Pancreatectomy With Islet Autotransplantation (Tpiat). Gastroenterology (2024)

Aida A. MetriMahya FaghihElizabeth ThompsonMichaël NoëRifat MannanRita KalyaniElham AfghaniVenkata S. AkshintalaZahra YousefliDaniel WarrenNiraj M. DesaiZhaoli SunChristi WalshMartin MakaryRalph HrubanJin HeVikesh Singh

clinical gastroenterologyemergency medicineepidemiologychronic pancreatitisgeneral surgerycomparative evaluationgastrointestinal oncologymedicineoutcomes researchvenereologygastrointestinal surgerydigestive diseasestotal pancreatectomydigestive system surgeryhepatologyislet autotransplantationfibrosisorgan transplantationgastroenterologypancreatitisrecurrent acute

3D Genomic Mapping Reveals Multifocality of Human Pancreatic Precancers. Nature (2024)

Alicia M. BraxtonAshley L. KiemenMia P. GrahnAndré ForjazJeeun ParksongJaanvi Mahesh BabuJiaying LaiLily ZhengNoushin NiknafsLiping JiangHaixia ChengQianqian SongRebecca ReichelSarah GrahamAlexander I. DamanakisCatherine G. FischerStephanie MouCameron MetzJulie GrangerXiao-Ding LiuNiklas BachmannYutong ZhuYunZhou LiuCristina Almagro-PérezAnn Chenyu JiangJeonghyun YooBridgette KimScott DuEli FosterJocelyn Y. HsuPaula Andreu RiveraLinda C. ChuFengze LiuElliot K. FishmanAlan YuilleNicholas J. RobertsElizabeth D. ThompsonRobert B. ScharpfToby C. CornishYuchen JiaoRachel KarchinRalph H. HrubanPei-Hsun WuDenis WirtzLaura D. Wood

genomicsgenome biologycancer researchcancer genomicsmolecular biologyhuman pancreatic precancers

3D Histology Reveals That Immune Response to Pancreatic Precancers is Heterogeneous and Depends on Global Pancreas Structure. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Ashley L. KiemenCristina Almagro-PérezValentina MatosAndre ForjazAlicia M. BraxtonLucie DequiedtJeeun ParksongCourtney D. CannonXuan YuanSarah M. ShinJaanvi Mahesh BabuElizabeth D. ThompsonToby C. CornishWon Jin HoLaura D. WoodPei-Hsun WuArrate Muñoz BarrutiaRalph H. HrubanDenis Wirtz

immunologyglobal pancreas structureimmune responsespancreatic precancers

Abstract 1206: Three-Dimensional Immune Atlas of Pancreatic Cancer Precursor Lesions Reveals Large Inter- and Intra-Lesion Heterogeneity. Cancer Research (2024)

Ashley L. KiemenCristina Almagro-PérezValentina Matos-RomeroAlicia M. BraxtonJaanvi Mahesh-BabuElizabeth D. ThompsonToby C. CornishPeiHsun WuLaura D. WoodArrate Muñoz-BarrutiaRalph H. HrubanDenis Wirtz

immunologycarcinogenesiscancer researchpancreatic cancerthree-dimensional immune atlasintra-lesion heterogeneityoncologytumor heterogeneitycancer biologypathologytumor biologyhealth sciences

Abstract 6092: Three-Dimensional Multi-Omic Analysis of Early Invasion of Human Pancreatic Ductal Adenocarcinoma From Ipmn. Cancer Research (2024)

Shalini DattaSarah M. ShinJessie KanacharoenMichael Johannes PflügerKatsuya HiroseAndré ForjazSarah GrahamPei-Hsun WuRalph H. HrubanDenis WirtzWon Jin HoAshley L. KiemenLaura D. Wood

cancer geneticspancreatic cancercancer careearly invasionmolecular cancercancer genomicscancer biologycancer researchtumor biologycarcinogenesisradiologyperineural invasionradiation oncologygeneticscancer imagingoncologyclinical researchmedicinal researchthree-dimensional multi-omic analysis

Abstract 7243: Crispr-Cas9 Genetic Targeting of Metastatic Pancreatic Cancer. Cancer Research (2024)

Kirsten BowlandJiaying LaiSelina Shiqing K. TehAlexis BennettAlyza SkaistYan ZhangElizabeth ThompsonRalph H. HrubanNicholas J. RobertsRachel KarchinChristine A. Iacobuzio-DonahueJames R. Eshleman

genomicscancer geneticsmetastatic pancreatic cancercancer researchpancreatic cancergeneticscancer genomicsmolecular biologyoncologycancer biologycrispr

A Confirmed Extrarenal Birt-Hogg-Dubé-Associated Oncocytic Neoplasm. The American Journal of Surgical Pathology (2024)

Ezra BarabanElliot K. FishmanKelly LafaroMing-Tseh LinYasser GedRalph H. HrubanPedram Argani

surgical pathologypathologyoncology

A Mucus Production Programme Promotes Classical Pancreatic Ductal Adenocarcinoma. Gut (2024)

Claudia TonelliGeorgi N YordanovYuan HaoAstrid DeschênesJuliene HindsPascal BelleauOlaf KlingbeilErin BrosnanAbhishek DoshiYoungkyu ParkRalph H HrubanChristopher R VakocAlexander DobinJonathan PreallDavid A Tuveson

immunologydigestive diseasesdermatologycancer carethoracic oncologycancer researchliver cancerpancreatic canceroncologygastroenterologyhepatologymedicinal researchgastrointestinal oncologymucus production programmetumor biology

Benign Islet Cells Within Peripancreatic Lymph Nodes. The American Journal of Surgical Pathology (2024)

Ezra BarabanElizabeth D. ThompsonAndres MatosoRalph H. HrubanPedram Argani

surgeryneurologyperipancreatic lymph nodeshematologyepidemiologyoncologybenign islet cellssurgical pathology

Clinical Relevance of Cancerization of Ducts in Resected Pancreatic Ductal Adenocarcinoma. Pancreas (2024)

Benedict Kinny-KösterYembur AhmadMichael J. PflügerJoseph R. HabibKohei FujikuraDanielle HutchingsJohn L. CameronChristopher R. ShubertKelly J. LafaroRichard A. BurkhartWilliam R. BurnsAmmar A. JavedJun YuRalph H. HrubanLaura D. WoodElizabeth D. ThompsonJin He

metastasispancreatic cancercancer carecancer managementcancer biologyclinical relevancedermatologycancer researchsurgical oncologycancer immunotherapypancreas transplantationhepatologypharmacologyradiation oncologygenitourinary cancerscancer imagingoncologymedicinal researchcellular therapy

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Ralph H. Hruban

Professor of Pathology Professor of Oncology

Johns Hopkins University

Affiliations

School of Medicine

Pathology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ralph H. Hruban

Johns Hopkins University

Professor of Pathology Professor of Oncology

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

3D Genomic Mapping Reveals Multifocality of Human Pancreatic Precancers. Nature (2024)

genomicsgenome biologycancer researchcancer genomicsmolecular biologyhuman pancreatic precancers

3D Histology Reveals That Immune Response to Pancreatic Precancers is Heterogeneous and Depends on Global Pancreas Structure. bioRxiv (Cold Spring Harbor Laboratory) (2024)

immunologyglobal pancreas structureimmune responsespancreatic precancers

Abstract 1206: Three-Dimensional Immune Atlas of Pancreatic Cancer Precursor Lesions Reveals Large Inter- and Intra-Lesion Heterogeneity. Cancer Research (2024)

immunologycarcinogenesiscancer researchpancreatic cancerthree-dimensional immune atlasintra-lesion heterogeneityoncologytumor heterogeneitycancer biologypathologytumor biologyhealth sciences

Abstract 6092: Three-Dimensional Multi-Omic Analysis of Early Invasion of Human Pancreatic Ductal Adenocarcinoma From Ipmn. Cancer Research (2024)

Shalini DattaSarah M. ShinJessie KanacharoenMichael Johannes PflügerKatsuya HiroseAndré ForjazSarah GrahamPei-Hsun WuRalph H. HrubanDenis WirtzWon Jin HoAshley L. KiemenLaura D. Wood

Abstract 7243: Crispr-Cas9 Genetic Targeting of Metastatic Pancreatic Cancer. Cancer Research (2024)

Kirsten BowlandJiaying LaiSelina Shiqing K. TehAlexis BennettAlyza SkaistYan ZhangElizabeth ThompsonRalph H. HrubanNicholas J. RobertsRachel KarchinChristine A. Iacobuzio-DonahueJames R. Eshleman

genomicscancer geneticsmetastatic pancreatic cancercancer researchpancreatic cancergeneticscancer genomicsmolecular biologyoncologycancer biologycrispr

A Confirmed Extrarenal Birt-Hogg-Dubé-Associated Oncocytic Neoplasm. The American Journal of Surgical Pathology (2024)

Ezra BarabanElliot K. FishmanKelly LafaroMing-Tseh LinYasser GedRalph H. HrubanPedram Argani

surgical pathologypathologyoncology

A Mucus Production Programme Promotes Classical Pancreatic Ductal Adenocarcinoma. Gut (2024)

Benign Islet Cells Within Peripancreatic Lymph Nodes. The American Journal of Surgical Pathology (2024)

Ezra BarabanElizabeth D. ThompsonAndres MatosoRalph H. HrubanPedram Argani

surgeryneurologyperipancreatic lymph nodeshematologyepidemiologyoncologybenign islet cellssurgical pathology

Clinical Relevance of Cancerization of Ducts in Resected Pancreatic Ductal Adenocarcinoma. Pancreas (2024)

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125
10 / page