Faculty

Institution

Unit

Venue

Jeffrey Moore

Professor; Graduate Coordinator; UMOVE Co-Director

University of Massachusetts Lowell

Affiliations

Kennedy College of Sciences

Biological Sciences

Jeffrey Moore is currently serving as a Biological Sciences Professor; Graduate Coordinator; UMOVE Co-Director at University of Massachusetts Lowell.

Honors

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Experiences

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Education

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Jeffrey Moore

University of Massachusetts Lowell

Professor; Graduate Coordinator; UMOVE Co-Director

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biophysics physiology genetics cardiology cell biology structural biology cardiomyopathy molecular biophysics protein science biomechanics experimental biophysics molecular physiology cellular physiology membrane biology applied physiology mammalian biology skeletal muscle molecular genetics muscle function cell and molecular biology electrophysiology animal physiology cell motility human physiology molecular regulation avian biology medical genetics biomolecular structure vascular biology physiological research cardiovascular physiology insect molecular biology biochemical sciences structural molecular biology cell biomechanics experimental biology cardiac muscle protein phosphorylation actuation thin filaments experimental medicine biological chemistry musculoskeletal science comparative physiology biomolecular interactions stretch activation muscle activation tropomyosin mutations circulatory physiology bone research cellular biology protein function developmental genetics musculoskeletal research musculoskeletal function protein transport biochemical genetics tissue physiology cell biophysics vitro motility tropomyosin binding thin filament function actin filaments osmoregulation cardiovascular function biocybernetics cellular regulatory mechanism fragmentation effect motor-driven properties force spectrum microscopy cell volume change stem cell fate vimentin intermediate filaments cytoplasmic mechanics cardiomyopathy phenotypes myosin motor molecular motors muscle contraction cellular motility

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Cross-Scale Conundrum: Slow Masticatory Myosin in Jaw Muscles That Are Both Fast and Strong. Biophysical Journal (2025)

Varun V. DhorajiaNicholas LaFaveBrandon RederRobert BrocklehurstNicolai KonowSam WalcottJeffrey R. Moore

physiologymuscular dystrophiesjaw muscleskinesiologymuscle functionskeletal musclecross-scale conundrummechanobiologyslow masticatory myosinbiomechanics

Bps2025 - Screening Single Nucleotide Changes to Tropomyosin to Identify Novel Cardiomyopathy Mutants. Biophysical Journal (2025)

Jian WenStuart G. CampbellJeffrey R. MooreWilliam LehmanMichael J. Rynkiewicz

biophysical chemistrybiophysicsbiophysical reviewnovel cardiomyopathy mutantssingle nucleotide changescardiomyopathy

Bps2025 - Small Molecules Targeting the Thin Filament Modulate Calcium Sensitivity and Reverse Cardiomyopathy Motility Phenotypes. Biophysical Journal (2025)

Meaghan E. BarryMichael J. RynkiewiczLauren E. BrownAaron B. BeelerJeffrey R. MooreWilliam LehmanBalajee Ramachandran

cardiomyopathybiophysical chemistrybiophysicscardiomyopathy motility phenotypes

Dual Role of Tropomyosin-R160 in Thin Filament Regulation: Insights Into Phosphorylation-Dependent Cardiac Relaxation and Cardiomyopathy Mechanisms. Archives of Biochemistry and Biophysics (2025)

Meaghan E BarryMichael J RynkiewiczJian WenAn-Yue TuMichael RegnierWilliam LehmanJeffrey R Moore

cardiologyphosphorylation-dependent cardiac relaxationbiophysicsgene expressionelectrophysiologycardiovascular physiologycardiovascular researchsystems biologyvascular biologymolecular and cellular biologyprotein phosphorylationcardiomyopathy mechanismsthin filament regulationmechanobiologycardiomyopathycardiac pathologiescardiac musclecell biology

Evaluating Pathogenicity of Tpm1 Variants of Unknown Significance Using In-Silico and In-Vitro Models. The Journal of Precision Medicine Health and Disease (2025)

tpm1 variantsvariant interpretationpathogenesisin-vitro modelssystems biologyimmune dysregulationmolecular diagnosticsinborn errors of immunityimmune responsespathologymolecular informatics

Klhl41 Orchestrates Sarcomere Assembly and Size to Drive Skeletal Muscle Hypertrophy in Vivo. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Hyewon HanJanet ShiAlfredo H BongiornoArian MansurJeffrey WidrickGrace TateSehajpreet GillEsmat KarimiHenk GranzierJeffrey R MooreVandana A Gupta

physiologygene expressioncellular physiologyskeletal muscle hypertrophymuscle functionskeletal musclebiological functionmolecular biologytissue (biology)cell biology

Multiscale Functional Specialization of Rodent Jaw Systems; Correlated Bite Force Adaptations at Molecular, Muscular, and Skeletal Scales. Research Square (Research Square) (2025)

physiologyzoologyallometric studiesmechanotransductionmorphology (biology)multiscale functional specializationrodent jaw systemsmechanobiologymusculoskeletal disordersdental biomechanicscomparative physiologybiomechanicsevolutionary biologybite force adaptations

Rat Superficial Masseter Operates at Long, Unstable Lengths During Biting. Research Square (Research Square) (2025)

physiologyrat superficial massetermammalian biologynervous system

Screening Single Nucleotide Changes to Tropomyosin to Identify Novel Cardiomyopathy Mutants. Journal of Molecular and Cellular Cardiology (2025)

Jian WenStuart CampbellJeffrey MooreWilliam LehmanMichael Rynkiewicz

cardiologynovel cardiomyopathy mutantssingle nucleotide changesmolecular and cellular biologymolecular biologycardiomyopathy

Classifying Pathogenicity of Tpm1 Variants of Unknown Significance Using in Vitro and in Silico Approaches. Journal of Cardiac Failure (2024)

Stuart CampbellJenette CresoIlayda FirlarSaiti HalderWilliam LehmanMichael RynkiewiczJeffrey Moore

cardiologypathogensvariant interpretationemergency medicineallelic variantunknown significancecritical carepathogen characterizationpathologycardiac pathologiespathway analysis

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Jeffrey Moore

Professor; Graduate Coordinator; UMOVE Co-Director

University of Massachusetts Lowell

Affiliations

Kennedy College of Sciences

Biological Sciences

Jeffrey Moore is currently serving as a Biological Sciences Professor; Graduate Coordinator; UMOVE Co-Director at University of Massachusetts Lowell.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Jeffrey Moore

University of Massachusetts Lowell

Professor; Graduate Coordinator; UMOVE Co-Director

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2025 - Cross-Scale Conundrum: Slow Masticatory Myosin in Jaw Muscles That Are Both Fast and Strong. Biophysical Journal (2025)

Varun V. DhorajiaNicholas LaFaveBrandon RederRobert BrocklehurstNicolai KonowSam WalcottJeffrey R. Moore

physiologymuscular dystrophiesjaw muscleskinesiologymuscle functionskeletal musclecross-scale conundrummechanobiologyslow masticatory myosinbiomechanics

Bps2025 - Screening Single Nucleotide Changes to Tropomyosin to Identify Novel Cardiomyopathy Mutants. Biophysical Journal (2025)

Jian WenStuart G. CampbellJeffrey R. MooreWilliam LehmanMichael J. Rynkiewicz

biophysical chemistrybiophysicsbiophysical reviewnovel cardiomyopathy mutantssingle nucleotide changescardiomyopathy

Bps2025 - Small Molecules Targeting the Thin Filament Modulate Calcium Sensitivity and Reverse Cardiomyopathy Motility Phenotypes. Biophysical Journal (2025)

Meaghan E. BarryMichael J. RynkiewiczLauren E. BrownAaron B. BeelerJeffrey R. MooreWilliam LehmanBalajee Ramachandran

cardiomyopathybiophysical chemistrybiophysicscardiomyopathy motility phenotypes

Dual Role of Tropomyosin-R160 in Thin Filament Regulation: Insights Into Phosphorylation-Dependent Cardiac Relaxation and Cardiomyopathy Mechanisms. Archives of Biochemistry and Biophysics (2025)

Meaghan E BarryMichael J RynkiewiczJian WenAn-Yue TuMichael RegnierWilliam LehmanJeffrey R Moore

Evaluating Pathogenicity of Tpm1 Variants of Unknown Significance Using In-Silico and In-Vitro Models. The Journal of Precision Medicine Health and Disease (2025)

tpm1 variantsvariant interpretationpathogenesisin-vitro modelssystems biologyimmune dysregulationmolecular diagnosticsinborn errors of immunityimmune responsespathologymolecular informatics

Klhl41 Orchestrates Sarcomere Assembly and Size to Drive Skeletal Muscle Hypertrophy in Vivo. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Hyewon HanJanet ShiAlfredo H BongiornoArian MansurJeffrey WidrickGrace TateSehajpreet GillEsmat KarimiHenk GranzierJeffrey R MooreVandana A Gupta

physiologygene expressioncellular physiologyskeletal muscle hypertrophymuscle functionskeletal musclebiological functionmolecular biologytissue (biology)cell biology

Multiscale Functional Specialization of Rodent Jaw Systems; Correlated Bite Force Adaptations at Molecular, Muscular, and Skeletal Scales. Research Square (Research Square) (2025)

Rat Superficial Masseter Operates at Long, Unstable Lengths During Biting. Research Square (Research Square) (2025)

physiologyrat superficial massetermammalian biologynervous system

Screening Single Nucleotide Changes to Tropomyosin to Identify Novel Cardiomyopathy Mutants. Journal of Molecular and Cellular Cardiology (2025)

Jian WenStuart CampbellJeffrey MooreWilliam LehmanMichael Rynkiewicz

cardiologynovel cardiomyopathy mutantssingle nucleotide changesmolecular and cellular biologymolecular biologycardiomyopathy

Classifying Pathogenicity of Tpm1 Variants of Unknown Significance Using in Vitro and in Silico Approaches. Journal of Cardiac Failure (2024)

Stuart CampbellJenette CresoIlayda FirlarSaiti HalderWilliam LehmanMichael RynkiewiczJeffrey Moore

cardiologypathogensvariant interpretationemergency medicineallelic variantunknown significancecritical carepathogen characterizationpathologycardiac pathologiespathway analysis

1
2
3
4
5
12
10 / page

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Similar Faculty Members

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human genetics

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Aldrin V. Gomes

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