Faculty

Institution

Unit

Venue

Raven H Huang

Professor Professor of Biochemistry Professor of Biophysics & Quantitative Biology

University of Illinois Urbana-Champaign

Affiliations

College of Liberal Arts & Sciences

School of Molecular & Cellular Biology

Department of Biochemistry

Raven H Huang is currently serving as a College Of Liberal Arts & Sciences Professor Professor of Biochemistry Professor of Biophysics & Quantitative Biology at University of Illinois Urbana-Champaign.

Honors

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Experiences

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Education

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Raven H Huang

University of Illinois Urbana-Champaign

Professor Professor of Biochemistry Professor of Biophysics & Quantitative Biology

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molecular biology structural molecular biology biomolecular structure nucleic acids biochemistry biological chemistry structural biology protein structure microbiology enzymes molecular cell biology protein science rna biology protein synthesis transcription (biology) rna processing gene expression crystal structures biosynthesis microbial pathogenesis biochemical sciences protein x-ray crystallography structure-function enzyme kinetics protein biosynthesis molecular microbiology essential rnas bacteria biomolecules enzyme inhibition enzyme catalysis nucleic acid chemistry rna structure prediction immunology antiviral research small rna immunologic mechanisms protein assembly bacteriology virulence factors molecular recognition protein function bacterial rna repair trna recognition colicin e5 lactococcus lactis cbass systems molecular metabolism bioenergetics peptides peptide science cellular biochemistry biological macromolecules radiation biology radiation exposure bioorganometallic chemistry cellular immune responses receptor (biochemistry) antigen processing innate immune system molecular immunology virus structure antiviral compounds synthetic virology natural product biosynthesis structural bioinformatics toxinology metabolic variety dpann radiations unusual biology radical mechanism archaeal elp3 broken rnas trna substrate indirect sequence readout wobble position escherichia coli bioinformatics database systems biology drug discovery computational biology bioinformatics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecular and Structural Basis of a Subfamily of Prfh Rescuing Both the Damaged and Intact Ribosomes Stalled in Translation. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Yannan TianQingrong LiShirin FatmaJunyi JiangHong JinFuxing ZengRaven H. Huang

molecular researchprotein functionprotein structurebiological chemistrycell and molecular biologyprotein biosynthesiscell biologymolecular cell biologybiomolecular structureprotein scienceprotein foldingnucleic acidsrna processingmolecular and cellular biologyprotein synthesistruncated mrnasspontaneous mrnas degradationmolecular biologystructural molecular biologycg prfh

Sequential Rescue and Repair of Stalled and Damaged Ribosome by Bacterial Prfh and Rtcb. Proceedings of the National Academy of Sciences (2022)

Yannan TianFuxing ZengAdrika RaybarmanShirin FatmaAmy CarruthersQingrong LiRaven H. Huang

rtcb2–prfh pairbacterial prfhbiomolecular structuremolecular cell biologyprotein synthesismolecular biologystructural molecular biologysequential rescuedna repairstructural biologyprotein biosynthesismicrobiologynucleic acids

Molecular Mechanisms of the Cdng-Cap5 Antiphage Defense System Employing 3’,2’-Cgamp as the Second Messenger. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Shirin FatmaArpita ChakravartiXuankun ZengRaven H. Huang

microbial pathogenesismolecular microbiologylactococcus lactisprotein structuremolecular and cellular biologybiomolecular structurechemical biologymolecular cell biologymolecular biologybiological chemistrystructural molecular biologyvirulence factorsbiomoleculesstructural biologycbass systemsmolecular recognitionmicrobiology

Molecular Mechanisms of the Cdng-Cap5 Antiphage Defense System Employing 3′,2′-Cgamp as the Second Messenger. Nature Communications (2021)

Shirin FatmaArpita ChakravartiXuankun ZengRaven H. Huang

microbial pathogenesismolecular microbiologycell signalingprotein structuremolecular and cellular biologylactococcus lactisbiomolecular structurechemical biologymolecular cell biologymolecular biologybiological chemistrystructural molecular biologyvirulence factorsbiomoleculesstructural biologycbass systemsmolecular recognitionmicrobiology

Ribotoxins Kill Cells by Chopping Off the Head of Trnas. Structure (2019)

Raven H. Huang

pathogenesismolecular and cellular biologyribotoxins kill cellstoxinsprotein synthesistoxinologymicrobiologycell biology

Biosynthetic Capacity, Metabolic Variety and Unusual Biology in the Cpr and Dpann Radiations. Nature Reviews Microbiology (2018)

Cindy J. CastelleChristopher T. BrownKarthik AnantharamanAlexander J. ProbstRaven H. HuangJillian F. Banfield

metabolic varietyradiation biologydpann radiationsunusual biologybiologymolecular metabolismmolecular biologybiological chemistrymetabolismradiation exposuremetabolic pathwaysbioenergeticsbiosynthesis

Double Methylation of Trna-U54 to 2′-O-Methylthymidine (Tm) Synergistically Decreases Immune Response by Toll-Like Receptor 7. Nucleic Acids Research (2018)

Patrick KellerIsabel FreundVirginie MarchandGuillaume BecRaven HuangYuri MotorinTatjana EigenbrodAlexander DalpkeMark Helm

immunologyreceptorsantiviral researchimmunologic mechanismsdouble methylationinnate immune systemallergymolecular immunologytlr7 responseimmune responsesimmunity (medicine)nucleic acids

Reconstitution and Substrate Specificity for Isopentenyl Pyrophosphate of the Antiviral Radical Sam Enzyme Viperin. Journal of Biological Chemistry (2018)

Arpita ChakravartiKiruthika SelvaduraiRezvan ShahoeiHugo LeeShirin FatmaEmad TajkhorshidRaven H. Huang

enzyme inhibitionvirus structureantiviral compoundssynthetic virologyprotein structureisopentenyl pyrophosphateenzymesvirologymolecular biologybiological chemistrysubstrate specificitybiochemical sciencesbiochemistry

Reconstitution and Structure of a Bacterial Pnkp1–Rnl–Hen1 Rna Repair Complex. Nature Communications (2015)

Pei WangKiruthika SelvaduraiRaven H. Huang

rna repairprotein assemblyprotein functionprotein structurebiomolecular structuremolecular cell biologyessential rnasmolecular biologystructural molecular biologyprotein x-ray crystallographystructural biologyprotein sciencecrystal structuresmicrobiologynucleic acids

Archaeal Elp3 Catalyzes Trna Wobble Uridine Modification at C5 via a Radical Mechanism. Nature Chemical Biology (2014)

Kiruthika SelvaduraiPei WangJoseph SeimetzRaven H Huang

bioorganic chemistryradical mechanismchemical biologyenzymesmolecular biologybiological chemistrybioorganometallic chemistryenzyme catalysisarchaeal elp3biochemical sciencesbiochemistry

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Raven H Huang

Professor Professor of Biochemistry Professor of Biophysics & Quantitative Biology

University of Illinois Urbana-Champaign

Affiliations

College of Liberal Arts & Sciences

School of Molecular & Cellular Biology

Department of Biochemistry

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Raven H Huang

University of Illinois Urbana-Champaign

Professor Professor of Biochemistry Professor of Biophysics & Quantitative Biology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecular and Structural Basis of a Subfamily of Prfh Rescuing Both the Damaged and Intact Ribosomes Stalled in Translation. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Yannan TianQingrong LiShirin FatmaJunyi JiangHong JinFuxing ZengRaven H. Huang

Sequential Rescue and Repair of Stalled and Damaged Ribosome by Bacterial Prfh and Rtcb. Proceedings of the National Academy of Sciences (2022)

Yannan TianFuxing ZengAdrika RaybarmanShirin FatmaAmy CarruthersQingrong LiRaven H. Huang

Molecular Mechanisms of the Cdng-Cap5 Antiphage Defense System Employing 3’,2’-Cgamp as the Second Messenger. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Shirin FatmaArpita ChakravartiXuankun ZengRaven H. Huang

Molecular Mechanisms of the Cdng-Cap5 Antiphage Defense System Employing 3′,2′-Cgamp as the Second Messenger. Nature Communications (2021)

Shirin FatmaArpita ChakravartiXuankun ZengRaven H. Huang

Ribotoxins Kill Cells by Chopping Off the Head of Trnas. Structure (2019)

Raven H. Huang

pathogenesismolecular and cellular biologyribotoxins kill cellstoxinsprotein synthesistoxinologymicrobiologycell biology

Biosynthetic Capacity, Metabolic Variety and Unusual Biology in the Cpr and Dpann Radiations. Nature Reviews Microbiology (2018)

Cindy J. CastelleChristopher T. BrownKarthik AnantharamanAlexander J. ProbstRaven H. HuangJillian F. Banfield

Double Methylation of Trna-U54 to 2′-O-Methylthymidine (Tm) Synergistically Decreases Immune Response by Toll-Like Receptor 7. Nucleic Acids Research (2018)

Patrick KellerIsabel FreundVirginie MarchandGuillaume BecRaven HuangYuri MotorinTatjana EigenbrodAlexander DalpkeMark Helm

immunologyreceptorsantiviral researchimmunologic mechanismsdouble methylationinnate immune systemallergymolecular immunologytlr7 responseimmune responsesimmunity (medicine)nucleic acids

Reconstitution and Substrate Specificity for Isopentenyl Pyrophosphate of the Antiviral Radical Sam Enzyme Viperin. Journal of Biological Chemistry (2018)

Arpita ChakravartiKiruthika SelvaduraiRezvan ShahoeiHugo LeeShirin FatmaEmad TajkhorshidRaven H. Huang

Reconstitution and Structure of a Bacterial Pnkp1–Rnl–Hen1 Rna Repair Complex. Nature Communications (2015)

Pei WangKiruthika SelvaduraiRaven H. Huang

Archaeal Elp3 Catalyzes Trna Wobble Uridine Modification at C5 via a Radical Mechanism. Nature Chemical Biology (2014)

Kiruthika SelvaduraiPei WangJoseph SeimetzRaven H Huang

bioorganic chemistryradical mechanismchemical biologyenzymesmolecular biologybiological chemistrybioorganometallic chemistryenzyme catalysisarchaeal elp3biochemical sciencesbiochemistry

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Satish K Nair

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University of Illinois Urbana-Champaign

drug discovery

clinical microbiology

Philip Bevilacqua

Institution

Pennsylvania State University

computational biology

rna biology

Arun Malhotra, Ph.D.

Institution

University of Miami

protein science

biochemistry

Scott K Silverman

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nucleic acid

biotechnology

John Gerlt

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metabolic pathway

molecular biology

William W Metcalf

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applied microbiology

gene expression

Jamie H. D. Cate

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University of California, Berkeley

structural biology

molecular informatics

Ryan Mehl

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Oregon State University

synthetic biology

biomolecular engineering

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protein science

protein energy landscapes

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systems biology

drug discovery