Faculty

Institution

Unit

Venue

Mary A Schuler

Professor of Cell & Developmental Biology Professor of Biochemistry

University of Illinois Urbana-Champaign

Affiliations

College of Liberal Arts & Sciences

School of Integrative Biology

School of Molecular & Cellular Biology

Department of Biochemistry

Department of Cell & Developmental Biology

Mary A Schuler is currently serving as a College Of Liberal Arts & Sciences Professor of Cell & Developmental Biology Professor of Biochemistry at University of Illinois Urbana-Champaign.

Honors

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Experiences

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Education

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Mary A Schuler

University of Illinois Urbana-Champaign

Professor of Cell & Developmental Biology Professor of Biochemistry

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biology genetics biochemistry molecular biology molecular genetics insect biochemistry drug metabolism gene expression insect molecular biology plant molecular biology genomics molecular metabolism molecular and cellular biology plant biochemistry genome biology toxins plant biotechnology plant cells chemical biology entomology toxicology plant physiology plant genomics biological chemistry molecular plant pathology plant science pesticide resistance nucleic acids insecticides insect science cell metabolism integrative plant biology biochemical genetics cytochrome p450 monooxygenases plant genetics biochemical sciences plant toxins rna processing gene structure phytochemistry plant biology splice site plant metabolism splicing variant experimental toxicology cytochrome p450 splice site selection furanocoumarin metabolism plant defense gene plant-insect interactions secondary metabolites toxicological mechanism natural product biosynthesis helicoverpa zea carbonyl metabolism gene regulation gene function transcription regulation cellular enzymology papilio polyxenes comparative genomics molecular adaptation gene evolution biochemical taxonomy rna biology cytochrome p450 genes genome sequencing plant hormones il 61801 p450 reductase angular furanocoumarins gene duplication black swallowtail cytochrome p450s active site actin genes gene sequence annotation functional genomics systems biology omics datasets drug discovery

Notable Scholarly Works

Notable Federal Grants

Collaborators

Catalytic Site Constraints in the P450S Mediating Loganic Acid (7Dlh) and Secologanic Acid Synthesis (Slas) in Camptotheca. Biochemistry (2023)

Priya RaoMark A. YaroslavskyJustin C. MillerMary A. Schuler

pharmacologycatalytic site constraintsenzymesmedicinal chemistryterpene indole alkaloidsbiological chemistrynatural product biosynthesisnatural product synthesisbiochemical sciencestight specificitynatural productschemical biologyphytochemistrypharmacognosybiosynthesisbiochemistrynatural product researchbiocatalysisorganic synthesisenzyme inhibition

Data From Mitochondrial Dna Repair Through Ogg1 Activity Attenuates Breast Cancer Progression and Metastasis. (2023)

Larysa V. YuzefovychAndrea G. KahnMichele A. SchulerLars EideRitu AroraGlenn L. WilsonMing TanLyudmila I. Rachek

metastasistumor biologymitochondrial functionradiation oncologymitochondrial dnacancer biologymitochondrial dna repaircell biologycancer cellscancer geneticsdna repaircell metabolismbreast cancer

Engineering C–C Bond Cleavage Activity Into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society (2023)

Justin C. MillerJoel H. Z. LeeMark A. McleanRebecca R. ChaoIsobella S. J. StoneTara L. PukalaJohn B. BruningJames J. De VossMary A. SchulerStephen G. SligarStephen G. Bell

biochemical sciencesenzymesmolecular metabolismbiomolecular engineeringbiocatalysisalcohol dehydrogenasesbiosynthesisbiochemistrycarbonyl metabolismprocess biochemistryp450 monooxygenase enzymemolecular biologymetabolic engineeringcytochrome p450human p450 cyp17a1

Single Mutations Toggle the Substrate Selectivity of Multifunctional Camptotheca Secologanic Acid Synthases. Journal of Biological Chemistry (2022)

Justin C. MillerMary A. Schuler

secondary metabolitesenzymesbiomolecular engineeringsls activitynatural productschemical biologyphytochemistrypharmacognosypredicted slsbiosynthesisbiological chemistrybiochemistryplant biochemistrynatural product biosynthesisnatural product researchcommon slsdrug discoverynatural product synthesis

P450 Variations Bifurcate the Early Terpene Indole Alkaloid Pathway in Catharanthus Roseus and Camptotheca Acuminata. Phytochemistry (2021)

Justin C. MillerAllison J. HollatzMary A. Schuler

catharanthus roseusdrug metabolismsecondary metabolitesnatural productsphytochemistryphytochemical analysiscamptotheca acuminatabiosynthesisplant biochemistrybiologybiochemistrypharmacologynatural product researchp450 variations

Nanodiscs as a New Tool to Examine Lipid–Protein Interactions. Methods in molecular biology (2019)

Ilia G. DenisovMary A. SchulerStephen G. Sligar

biophysicsnanodiscbiomoleculeslipidsexamine lipid–protein interactions

Substrate‐Specificity of Cytochrome P450‐Mediated Detoxification as an Evolutionary Strategy for Specialization on Furanocoumarin‐Containing Hostplants: Cyp6ae89 in Parsnip Webworms. Insect Molecular Biology (2019)

B. CallaW.‐Y. WuC. A. E. DeanM. A. SchulerM. R. Berenbaum

molecular evolutionbiochemical taxonomygeneticsdrug metabolismparasite genomicsmolecular and cellular biologyinsect molecular biologyspecialized cytochrome p450insect biochemistrycytochrome p450‐mediated detoxificationbiological chemistrybiologycytochrome p450smolecular biologytoxins

Allele-Defined Genome of the Autopolyploid Sugarcane Saccharum Spontaneum L.. Nature Genetics (2018)

Jisen ZhangXingtan ZhangHaibao TangQing ZhangXiuting HuaXiaokai MaFan ZhuTyler JonesXinguang ZhuJohn BowersChing Man WaiChunfang ZhengYan ShiShuai ChenXiuming XuJingjing YueDavid R. NelsonLixian HuangZhen LiHuimin XuDong ZhouYongjun WangWeichang HuJishan LinYoujin DengNeha PandeyMelina ManciniDessireé ZerpaJulie K. NguyenLiming WangLiang YuYinghui XinLiangfa GeJie ArroJennifer O. HanSetu ChakrabartyMarija PushkoWenping ZhangYanhong MaPanpan MaMingju LvFaming ChenGuangyong ZhengJingsheng XuZhenhui YangFang DengXuequn ChenZhenyang LiaoXunxiao ZhangZhicong LinHai LinHansong YanZheng KuangWeimin ZhongPingping LiangGuofeng WangYuan YuanJiaxian ShiJinxiang HouJingxian LinJingjing JinPeijian CaoQiaochu ShenQing JiangPing ZhouYaying MaXiaodan ZhangRongrong XuJuan LiuYongmei ZhouHaifeng JiaQing MaRui QiZhiliang ZhangJingping FangHongkun FangJinjin SongMengjuan WangGuangrui DongGang WangZheng ChenTeng MaHong LiuSingha R. DhunganaSarah E. HussXiping YangAnupma SharmaJhon H. TrujilloMaria C. MartinezMatthew HudsonJohn J. RiascosMary SchulerLi-Qing ChenDavid M. BraunLei LiQingyi YuJianping WangKai WangMichael C. SchatzDavid Heckerman

molecular evolutioncomparative genomicsgeneticsgenome sequencingmolecular geneticsallele-defined genomedisease resistancesugarcane chromosomegenomicsbiologyevolutionary biologymolecular ecologygenetic variationgenome biology

Loganic Acid Methyltransferase: Insights Into the Specificity of Methylation on an Iridoid Glycoside. ChemBioChem (2018)

Nektaria PetronikolouAllison J. HollatzMary A. SchulerSatish K. Nair

secondary metabolitesnatural productsbioactive compoundsmedicinal chemistrypharmacognosybioorganic chemistrybiosynthesisbiochemistrypharmacologynatural product biosynthesisindole alkaloidsnatural product researchiridoid glycosideglycosylationenzyme inhibitionnatural product synthesisbiotransformationloganic acid methyltransferase

Pastinaca Sativa P450S - Cyp71Aj4 Variants in New Zealand and North America. (2018)

Anne CureBernarda CallaMay BerenbaumMary Schuler

new zealandpharmacologymolecular pharmacologycyp71aj4 variantspastinaca sativa p450sdrug discovery

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Mary A Schuler

Professor of Cell & Developmental Biology Professor of Biochemistry

University of Illinois Urbana-Champaign

Affiliations

College of Liberal Arts & Sciences

School of Integrative Biology

School of Molecular & Cellular Biology

Department of Biochemistry

Department of Cell & Developmental Biology

Mary A Schuler is currently serving as a College Of Liberal Arts & Sciences Professor of Cell & Developmental Biology Professor of Biochemistry at University of Illinois Urbana-Champaign.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mary A Schuler

University of Illinois Urbana-Champaign

Professor of Cell & Developmental Biology Professor of Biochemistry

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Catalytic Site Constraints in the P450S Mediating Loganic Acid (7Dlh) and Secologanic Acid Synthesis (Slas) in Camptotheca. Biochemistry (2023)

Priya RaoMark A. YaroslavskyJustin C. MillerMary A. Schuler

Data From Mitochondrial Dna Repair Through Ogg1 Activity Attenuates Breast Cancer Progression and Metastasis. (2023)

Larysa V. YuzefovychAndrea G. KahnMichele A. SchulerLars EideRitu AroraGlenn L. WilsonMing TanLyudmila I. Rachek

metastasistumor biologymitochondrial functionradiation oncologymitochondrial dnacancer biologymitochondrial dna repaircell biologycancer cellscancer geneticsdna repaircell metabolismbreast cancer

Engineering C–C Bond Cleavage Activity Into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society (2023)

Justin C. MillerJoel H. Z. LeeMark A. McleanRebecca R. ChaoIsobella S. J. StoneTara L. PukalaJohn B. BruningJames J. De VossMary A. SchulerStephen G. SligarStephen G. Bell

Single Mutations Toggle the Substrate Selectivity of Multifunctional Camptotheca Secologanic Acid Synthases. Journal of Biological Chemistry (2022)

Justin C. MillerMary A. Schuler

P450 Variations Bifurcate the Early Terpene Indole Alkaloid Pathway in Catharanthus Roseus and Camptotheca Acuminata. Phytochemistry (2021)

Justin C. MillerAllison J. HollatzMary A. Schuler

Nanodiscs as a New Tool to Examine Lipid–Protein Interactions. Methods in molecular biology (2019)

Ilia G. DenisovMary A. SchulerStephen G. Sligar

biophysicsnanodiscbiomoleculeslipidsexamine lipid–protein interactions

B. CallaW.‐Y. WuC. A. E. DeanM. A. SchulerM. R. Berenbaum

Allele-Defined Genome of the Autopolyploid Sugarcane Saccharum Spontaneum L.. Nature Genetics (2018)

Loganic Acid Methyltransferase: Insights Into the Specificity of Methylation on an Iridoid Glycoside. ChemBioChem (2018)

Nektaria PetronikolouAllison J. HollatzMary A. SchulerSatish K. Nair

Pastinaca Sativa P450S - Cyp71Aj4 Variants in New Zealand and North America. (2018)

Anne CureBernarda CallaMay BerenbaumMary Schuler

new zealandpharmacologymolecular pharmacologycyp71aj4 variantspastinaca sativa p450sdrug discovery

1
2
3
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5
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10 / page

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