Faculty

Institution

Unit

Venue

Alireza Ghanbarpour

Assistant Professor

Washington University in St. Louis

Affiliations

School of Medicine

Department of Biochemistry and Molecular Biophysics

Alireza Ghanbarpour is currently serving as a Biochemistry And Molecular Biophysics Assistant Professor at Washington University In St. Louis.

Honors

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Experiences

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Education

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Alireza Ghanbarpour

Washington University in St. Louis

Assistant Professor

You can click a keyword to filter the displayed items

molecular biology protein structure protein science biochemistry structural molecular biology structural biology protein assembly biomolecular engineering biomolecular structure biophysics protein folding protein engineering enzymes membrane biology transition metal chemistry biological macromolecules biomolecules coordination chemistry protein transport biophysical chemistry fluorescence molecular structure multi-protein assembly chemical sciences organic process research photophysical properties mechanistic photochemistry structure-function enzyme kinetics protein refolding coordination complex ftsh proteolysis membrane science liver physiology vascular biology cell metabolism redox biology material chemistry lipid movement proteinlipid interaction membrane systems organelle biogenesis heme homeostasis functional regulation lipid science lipoprotein metabolism mitochondrial function excitation energy transfer chemisorption metal-organic polyhedron extractive metallurgy catalytic synthesis molecular catalysis heterogeneous catalysis synthetic chemistry reaction intermediates supramolecular assemblies plant biochemistry redox chemistry organometallic catalysis sustainable synthesis sensor suite membrane expansion lipid transfer proteins lipid homeostasis er scramblase lipoprotein biogenesis engineered photobase metal-organic framework ultra traces solid-phase extraction new molybdenum theoretical study halogen⋯halogen interaction protein switches new class hcrbpii domain-swapped dimer protein function

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Asymmetric Nautilus-Like Hflk/C Assembly Controls Ftsh Proteolysis of Membrane Proteins. The EMBO Journal (2025)

biological macromoleculesprotein secretionmembrane transportmembranesprotein transportftsh proteolysisbiomolecular engineeringmolecular biologymembrane proteinsbiochemistryprotein scienceprotein folding

Exploiting a Rational β-Strand Insertion Strategy and Disulfide Locking to Mechanically Manipulate Domain-Swapped Protein Structures. Structure (2025)

molecular biophysicsmacromolecular machinesprotein assemblyprotein refoldingdomain-swapped protein structuresprotein structuredisulfide lockingbiomolecular structurebiomolecular engineeringmolecular biologystructural molecular biologybiomoleculesstructural biologyprotein scienceprotein engineeringmulti-protein assemblybiochemistry

Regulation of the Essential Transmembrane Aaa+ Protease Ftsh by Hflk/C Oligomeric Assembly. Structural Dynamics (2025)

biological macromoleculesprotein assemblyprotein secretionprotein functionprotein structureprotein transportenzymeshflk/c oligomeric assemblymolecular biologymembrane proteinsbiological chemistrystructural molecular biologycellular biochemistryprotein sciencemembrane biologymulti-protein assemblybiochemistry

Structural Insights Into the Pseudomonas Aeruginosa Clpp1 • Clpp2 Heterocomplex and Its Interactions With the Aaa + Clpx Unfoldase. Protein Science (2025)

biological macromoleculesmicrobial pathogenesisstructural insightsbacteriologymolecular microbiologybacteriaprotein structureapplied microbiologymicrobial proteomicsbiomolecular structurepathogenic bacteriamolecular biologystructural molecular biologybiomoleculesstructural biologybiofilmsmicrobiology

Structural Plasticity of the Membrane-Bound Protein Degradation Assembly Supports Bacterial Adaptation to Stress. bioRxiv (Cold Spring Harbor Laboratory) (2025)

protein assemblystructural plasticitymolecular microbiologystructural biologyprotein structurebiomolecular structuremolecular biologymembrane proteinsbacteriaprotein sciencemicrobiology

An Asymmetric Nautilus-Like Hflk/C Assembly Controls Ftsh Proteolysis of Membrane Proteins. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Alireza GhanbarpourBertina TelusmaBarrett M. PowellJia Jia ZhangIsabella BolstadCarolyn VargasSandro KellerTania BakerRobert T. SauerJoseph H. Davis

biophysicsprotein assemblymembranesprotein structureftsh proteolysismolecular biologymembrane proteinsmembrane biologybiochemistry

A Proteolytic Aaa+ Machine Poised to Unfold Protein Substrates. Nature Communications (2024)

Alireza GhanbarpourRobert T. SauerJoseph H. Davis

protein assemblyprotein structurebiomolecular engineeringprotein synthesisprotein substratesprotein scienceprotein engineeringprotein folding

Regulation of Absorption and Emission in a Protein/Fluorophore Complex. ACS Chemical Biology (2024)

fluorescence spectroscopybiophysical chemistrybiophysicsmolecular biophysicsbiochemical interactionprotein assemblybiomolecular interactionsprotein/fluorophore complexfluorescencestructural molecular biologybiochemistryprotein scienceprotein folding

A Closed Translocation Channel in the Substrate-Free Aaa+ Clpxp Protease Diminishes Rogue Degradation. Nature Communications (2023)

Alireza GhanbarpourSteven E. CohenXue FeiLaurel F. KinmanTristan A. BellJia Jia ZhangTania A. BakerJoseph H. DavisRobert T. Sauer

biophysicsgeneticsclosed translocation channelmolecular biologyrogue degradationmembrane biology

A Proteolytic Aaa+ Machine Poised to Unfold a Protein Substrate. bioRxiv (Cold Spring Harbor Laboratory) (2023)

molecular motorsprotein chemistryprotein refoldingprotein structureproteolytic aaa+ machineenzymesmolecular biologystructural molecular biologybiochemistrybiomolecular structureprotein scienceprotein folding

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Alireza Ghanbarpour

Assistant Professor

Washington University in St. Louis

Affiliations

School of Medicine

Department of Biochemistry and Molecular Biophysics

Alireza Ghanbarpour is currently serving as a Biochemistry And Molecular Biophysics Assistant Professor at Washington University In St. Louis.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alireza Ghanbarpour

Washington University in St. Louis

Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

An Asymmetric Nautilus-Like Hflk/C Assembly Controls Ftsh Proteolysis of Membrane Proteins. The EMBO Journal (2025)

Exploiting a Rational β-Strand Insertion Strategy and Disulfide Locking to Mechanically Manipulate Domain-Swapped Protein Structures. Structure (2025)

Regulation of the Essential Transmembrane Aaa+ Protease Ftsh by Hflk/C Oligomeric Assembly. Structural Dynamics (2025)

Structural Insights Into the Pseudomonas Aeruginosa Clpp1 • Clpp2 Heterocomplex and Its Interactions With the Aaa + Clpx Unfoldase. Protein Science (2025)

Structural Plasticity of the Membrane-Bound Protein Degradation Assembly Supports Bacterial Adaptation to Stress. bioRxiv (Cold Spring Harbor Laboratory) (2025)

protein assemblystructural plasticitymolecular microbiologystructural biologyprotein structurebiomolecular structuremolecular biologymembrane proteinsbacteriaprotein sciencemicrobiology

An Asymmetric Nautilus-Like Hflk/C Assembly Controls Ftsh Proteolysis of Membrane Proteins. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Alireza GhanbarpourBertina TelusmaBarrett M. PowellJia Jia ZhangIsabella BolstadCarolyn VargasSandro KellerTania BakerRobert T. SauerJoseph H. Davis

biophysicsprotein assemblymembranesprotein structureftsh proteolysismolecular biologymembrane proteinsmembrane biologybiochemistry

A Proteolytic Aaa+ Machine Poised to Unfold Protein Substrates. Nature Communications (2024)

Alireza GhanbarpourRobert T. SauerJoseph H. Davis

protein assemblyprotein structurebiomolecular engineeringprotein synthesisprotein substratesprotein scienceprotein engineeringprotein folding

Regulation of Absorption and Emission in a Protein/Fluorophore Complex. ACS Chemical Biology (2024)

A Closed Translocation Channel in the Substrate-Free Aaa+ Clpxp Protease Diminishes Rogue Degradation. Nature Communications (2023)

Alireza GhanbarpourSteven E. CohenXue FeiLaurel F. KinmanTristan A. BellJia Jia ZhangTania A. BakerJoseph H. DavisRobert T. Sauer

biophysicsgeneticsclosed translocation channelmolecular biologyrogue degradationmembrane biology

A Proteolytic Aaa+ Machine Poised to Unfold a Protein Substrate. bioRxiv (Cold Spring Harbor Laboratory) (2023)

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