Faculty

Institution

Unit

Venue

Eric C Chang

Professor

Baylor College of Medicine

Affiliations

Molecular and Cellular Biology

Eric C Chang is currently serving as a Molecular And Cellular Biology Professor at Baylor College of Medicine.

Honors

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Experiences

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Education

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Eric C Chang

Baylor College of Medicine

Professor

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molecular biology cell biology molecular cell biology yeast molecular and cellular biology cell division genetics oncogenes biological chemistry cancer biology cell signaling signal transduction tumor biology protein function cellular biochemistry biochemistry cell and molecular biology cancer cells molecular cancer cell cycle molecular genetics protein science gene expression fungal genetics structural molecular biology breast oncology proteome research cancer discovery cell regulation medicinal research cell research cancer genetics signaling pathways cellular biology molecular research redox biology nucleic acids molecular regulation cancer genomics intracellular trafficking chromosome biology protein assembly fungal cell biology proper spindle formation mammalian biology prognosis functional modification reactive oxygen species cell polarity protein phosphorylation molecular neurobiology prognostic effects er-positive breast cancer somatic mutations cooperative interaction neurofibromin isoforms degradation machineries mitotic fidelity ras pathways tumor targeting short-term variability clinical evidence interactomics protein synthesis anti-cancer agents oncogenic agent remedial action biological inorganic chemistry bioactive metal gtpase-activating protein activity aggressive subset kras inhibitors dioxygen stress superoxide scavenging activity intracellular mn tumor formation metastasis cancer growth tumor growth systems biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Integrative Spatial Omics Reveals Distinct Tumor-Promoting Multicellular Niches and Immunosuppressive Mechanisms in Black American and White American Patients With Tnbc. Nature Communications (2025)

cancer biologycellular immune responsesimmune responsescancer cellstumor microenvironmentimmunosuppressive mechanismscancer discoverytumor biologyimmunologycancer immunosurveillancewhite american patientscell biologyblack american

Nf1-Depleted Er+ Breast Cancers Are Differentially Sensitive to Cdk4/6 Inhibitors. Sci. Transl. Med. (2025)

cancer biologymolecular cancerbreast cancercancer cellsoncogenesbreast oncologyoncologyradiation oncologytumor biologycdk4/6 inhibitorscell biology

Nf1-Depleted Er + Breast Cancers Are Differentially Sensitive to Cdk4/6 Inhibitors. Science Translational Medicine (2025)

cancer biologymolecular cancertumor suppressorsbreast cancercancer cellsoncogenesbreast oncologytumor microenvironmentoncologyradiation oncologytumor biologycdk4/6 inhibitorscell biologyendocrine-related cancers

Abstract Gs01-08: Cdk4/6 Inhibition is a Potential Vulnerability in Nf1-Depleted Er+ Breast Cancer. Cancer Research (2024)

Ze-Yi ZhengAnran ChenEric JaehnigMeenakshi AnuragJonathan LeiChenwei WangLong FengPurba SinghHilda KennedyJin CaoGhazal YadavJill TsaiXi ChenCharles FouldsBora LimMatthew EllisBing ZhangEric Chang

cancer biologycancer treatmentbreast canceroncogenescancer researchoncologymolecular biologytumor biology

Abstract Lb213: Nf1 Loss Promotes Bone Metastasis in Estrogen Receptor Positive Breast Cancer. Cancer Research (2024)

Zifan ZhaoZe-Yi ZhengJonathan LeiMatthew J. BaikYi-Hsuan WuJunkai WangIgor BadoMeenakshi AnuragBing ZhangXiang ZhangEric Chang

cancer researchcancer biologybreast cancerbone metastasis

Ductal Carcinoma in Situ: Molecular and Cellular Basis of Malignancy.. Journal of Clinical Oncology (2024)

Fariba BehbodEmre ArslanQian ZhuYan HongBenjamin StropeJamie L. WagnerKelsey E. LarsonTimothy FieldsAllison AripoliAshley HuppeOnalisa WinbladChrista BalanoffJessica PetersonMolly HillCamron SmithEric ChangAndrew K. GodwinSeema Ahsan KhanCarol J. FabianKunal Rai

cancer biologycancer imagingcancer cellscancer researchoncologyclinical radiation oncologyradiation oncologysurgical oncologymolecular biologyclinical mycologytumor biologyclinical researchmedicinal researchductal carcinomacell biologycancer carecellular basismolecular basis

Abstract P5-05-03: Characterization of the Genomic Landscape of Breast Carcinoma Patients With Nf1 Alterations Using Comprehensive Cell-Free Tumor Dna Next-Generation Sequencing. Cancer Research (2023)

pathologynf1 alterationsgenomic landscapebreast cancerbreast oncologyoncogenescancer researchoncologytumor heterogeneitycancer genomicscancer discoveryradiation oncologysystems biologycancer geneticscancer cellsmolecular diagnosticsbreast carcinoma patients

Modulation of the Proteostasis Network Promotes Tumor Resistance to Oncogenic Kras Inhibitors. Science (2023)

Xiangdong LvXuan LuJin CaoQin LuoYao DingFanglue PengApar PataerDong LuDong HanEric MalmbergDoug W. ChanXiaoran WangSara R. SavageSufeng MaoJingjing YuFei PengLiang YanHuan MengLaure ManeixYumin HanYiwen ChenWantong YaoEric C. ChangAndre CaticXia LinGeorge MilesPengxiang HuangZheng SunBryan BurtHuamin WangJin WangQizhi Cathy YaoBing ZhangJack A. RothBert W. O’MalleyMatthew J. EllisMothaffar F. RimawiHaoqiang YingXi Chen

pathologydrug resistancecell regulationanti-cancer agentsfunctional modificationtumor biologypharmacologyoncogenic agentoncologycellular therapyremedial actioncancer immunotherapyoncogeneskras inhibitorsenzyme inhibitionleukemiasystems biologymedicinal researchtherapeutic targets

Abstract 2979: Elevated Nras Expression as a Potential Driver of Dcis Progression to Basal-Like Invasive Breast Cancer. Cancer Research (2022)

Ze-yi ZhengHanan ElsarrajYang HongJonathan T. LeiMeenakshi AnuragYichao ShenFlora LoLong FengZifan ZhaoXiang H. ZhangFariba BehbodEric C. Chang

cancer researchdcis progressioncancer biologybreast cancer

Elevated Nras Expression During Dcis is a Potential Driver for Progression to Basal-Like Properties and Local Invasiveness. Breast Cancer Research (2022)

Ze-Yi ZhengHanan ElsarrajJonathan T. LeiYan HongMeenakshi AnuragLong FengHilda KennedyYichao ShenFlora LoZifan ZhaoBing ZhangXiang H.-F. ZhangOssama W. TawfikFariba BehbodEric C. Chang

nras expressioncancer biologylocal invasivenessbreast cancercancer researchbasal-like properties

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Eric C Chang

Professor

Baylor College of Medicine

Affiliations

Molecular and Cellular Biology

Eric C Chang is currently serving as a Molecular And Cellular Biology Professor at Baylor College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Eric C Chang

Baylor College of Medicine

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Nf1-Depleted Er+ Breast Cancers Are Differentially Sensitive to Cdk4/6 Inhibitors. Sci. Transl. Med. (2025)

cancer biologymolecular cancerbreast cancercancer cellsoncogenesbreast oncologyoncologyradiation oncologytumor biologycdk4/6 inhibitorscell biology

Nf1-Depleted Er + Breast Cancers Are Differentially Sensitive to Cdk4/6 Inhibitors. Science Translational Medicine (2025)

Abstract Gs01-08: Cdk4/6 Inhibition is a Potential Vulnerability in Nf1-Depleted Er+ Breast Cancer. Cancer Research (2024)

Ze-Yi ZhengAnran ChenEric JaehnigMeenakshi AnuragJonathan LeiChenwei WangLong FengPurba SinghHilda KennedyJin CaoGhazal YadavJill TsaiXi ChenCharles FouldsBora LimMatthew EllisBing ZhangEric Chang

cancer biologycancer treatmentbreast canceroncogenescancer researchoncologymolecular biologytumor biology

Abstract Lb213: Nf1 Loss Promotes Bone Metastasis in Estrogen Receptor Positive Breast Cancer. Cancer Research (2024)

Zifan ZhaoZe-Yi ZhengJonathan LeiMatthew J. BaikYi-Hsuan WuJunkai WangIgor BadoMeenakshi AnuragBing ZhangXiang ZhangEric Chang

cancer researchcancer biologybreast cancerbone metastasis

Ductal Carcinoma in Situ: Molecular and Cellular Basis of Malignancy.. Journal of Clinical Oncology (2024)

Modulation of the Proteostasis Network Promotes Tumor Resistance to Oncogenic Kras Inhibitors. Science (2023)

Abstract 2979: Elevated Nras Expression as a Potential Driver of Dcis Progression to Basal-Like Invasive Breast Cancer. Cancer Research (2022)

Ze-yi ZhengHanan ElsarrajYang HongJonathan T. LeiMeenakshi AnuragYichao ShenFlora LoLong FengZifan ZhaoXiang H. ZhangFariba BehbodEric C. Chang

cancer researchdcis progressioncancer biologybreast cancer

Elevated Nras Expression During Dcis is a Potential Driver for Progression to Basal-Like Properties and Local Invasiveness. Breast Cancer Research (2022)

Ze-Yi ZhengHanan ElsarrajJonathan T. LeiYan HongMeenakshi AnuragLong FengHilda KennedyYichao ShenFlora LoZifan ZhaoBing ZhangXiang H.-F. ZhangOssama W. TawfikFariba BehbodEric C. Chang

nras expressioncancer biologylocal invasivenessbreast cancercancer researchbasal-like properties

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Ramani Ramchandran

Institution

Medical College of Wisconsin

organelle biogenesis

developmental biology

Michael A Mancini

Institution

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molecular cell biology

cell biology

Qin, Jun

Institution

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molecular biology

proteomics

Cristian Coarfa

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omics

multi-omics studies

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cancer biology

Simone Sidoli

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