Faculty

Institution

Unit

Venue

Dmitri Davydov

Research Professor

Washington State University

Affiliations

College of Arts and Sciences

Department of Chemistry

Dmitri Davydov is currently serving as a College Of Arts And Sciences Research Professor at Washington State University.

Honors

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Experiences

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Education

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Dmitri Davydov

Washington State University

Research Professor

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pharmacology biochemistry molecular biology biophysics protein science enzymes membrane biology structural biology drug metabolism redox biology biophysical chemistry protein structure medicinal chemistry biological chemistry molecular biophysics enzyme inhibition pharmacokinetics human liver microsomes substrate binding biochemical sciences medicinal research liver physiology biomolecular interactions molecular microbiology pharmacological research molecular metabolism conformational studies structure-function enzyme kinetics protein chemistry cytogenetics biological inorganic chemistry fluorescent probe high-pressure spectroscopy allosteric mechanisms pressure-perturbation spectroscopy plant physiology plant science clinical biochemistry clinical pharmacology enzyme catalysis plant metabolism plant biochemistry absorption spectroscopy microsomal monooxygenase conformational heterogeneity flavin domain heme pocket functional heterogeneity active site sorghum bicolor applied pharmacology free radical biology antioxidants clinical chemistry redox chemistry oxygen reduction reaction reactive oxygen species metabolic regulation redox signaling rational drug design clinical toxicology toxicokinetics cellular enzymology plant biology crop physiology apoptosis heme signaling heme transport biochemical interaction drug development experimental biology homogenization (chemistry) cyanobacteria multiple binding sites multiple conformers conformational inhomogeneity protein structure prediction biomolecular structure protein modeling protein biophysics

Notable Scholarly Works

Notable Federal Grants

Collaborators

Differential Tissue Abundance of Membrane-Bound Drug Metabolizing Enzymes and Transporter Proteins by Global Proteomics. Drug Metabolism and Disposition (2024)

Dilip Kumar SinghDeepak AhireDmitri R. DavydovBhagwat Prasad

medicinal chemistrypharmacogenomicsdrug metabolismtransporter proteinsclinical proteomicsmedicineproteomicsmembrane transportpharmacokineticsdrug analysisprotein transportglobal proteomicsenzymesprotein sciencedermatologyenzyme specificitytumor biologyenzyme inhibitionpharmacologymedicinal research

Effects of Alcohol Consumption and Tobacco Smoking on the Composition of the Ensemble of Drug Metabolizing Enzymes and Transporters in Human Liver. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Kari A. GaitherDilip Kumar SinghGuihua YueJulia TrudeauKannapiran PonrajNadezhda Y. DavydovaPhilip LazarusDmitri R. DavydovBhagwat Prasad

medicinal chemistrydrug metabolismepidemiologycannabis useliver physiologyalcohol consumptionrespiratory toxicologypharmacokineticstobacco smokingenzymesmembrane biologyhealth sciencescell metabolismmolecular metabolismhepatologyexperimental toxicologypharmacological researchpulmonary pharmacologypharmacologyredox biologydrug metabolizing enzymeshuman liver

Interplay of Alcohol Intake, Smoking, and Sex on the Protein Abundance of Hepatic Drug Metabolizing Enzymes and Transporters in Humans. (2024)

Kari GaitherDilip K. SinghGuihua E. YueJulia TrudeauKannapiran PonrajPhilip LazarusDmitri R. DavydovBhagwat Prasad

medicinal chemistrypharmacologypharmacokineticsdrug metabolismepidemiologyalcohol intakehepatic drugclinical biochemistryprotein abundancehepatologymedicinal researchmetabolismhealth sciencespharmacological research

Non-Additivity of the Functional Properties of Individual P450 Species and Its Manifestation in the Effects of Alcohol Consumption on the Metabolism of Ketamine and Amitriptyline. Biochemical Pharmacology (2024)

Kannapiran PonrajKari A GaitherDilip Kumar SinghNadezhda DavydovaMengqi ZhaoShaman LuoPhillip LazarusBhagwat PrasadDmitri R Davydov

alcohol consumptionpharmacologypharmacokineticsdrug metabolismmolecular biologymetabolismbiochemistry

Non-Additivity of the Functional Properties of P450 Enzymes in the Human Drug-Metabolizing Ensemble Revealed in a Study With a Series of Individual Microsomal Preparations. (2024)

Kannapiran PonrajKari GaitherDilip K. SinghBhagwat PrasadDmitri R. Davydov

pharmacologydrug metabolismhuman drug-metabolizing ensembleenzymesmolecular biologymetabolism

Quantitative Proteomics Identifies Significant Changes in the Abundance and Composition of Hepatic Drug Metabolizing Enzymes in Heavy Alcohol Drinkers. Drug Metabolism and Pharmacokinetics (2024)

Kari GaitherDilip Kumar SinghGuihua YueJulia TrudeauNadezhda DavydovaDmitri R. DavydovPhilip LazarusBhagwat Prasad

medicinal chemistrymedicineproteomicspharmacologypharmacokineticsdrug metabolismenzymeshepatologypathologyheavy alcohol drinkers

High-Throughput Assay of Cytochrome P450-Dependent Drug Demethylation Reactions and Its Use to Re-Evaluate the Pathways of Ketamine Metabolism. Biology (2023)

Nadezhda Y. DavydovaDavid A. HutnerKari A. GaitherDilip Kumar SinghBhagwat PrasadDmitri R. Davydov

immunologypharmacologydrug metabolismketamine metabolismhigh-throughput assaypathway analysisneuroscience

Conformational Rearrangements in the Redox Cycling of Nadph-Cytochrome P450 Reductase From Sorghum Bicolor Explored With Fret and Pressure-Perturbation Spectroscopy. Biology (2022)

Bixia ZhangChulHee KangDmitri R. Davydov

sorghum bicolorenzymesmolecular biologyconformational rearrangementsredox cyclingpressure-perturbation spectroscopyprotein sciencebiochemistry

Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes With Chemical Crosslinking Mass Spectrometry. Biomolecules (2022)

Dmitri R. DavydovBikash DangiGuihua YueDeepak S. AhireBhagwat PrasadVictor G. Zgoda

biomolecular interactionspharmacologyinteractomicshuman liver microsomesmolecular biologymass spectrometrycell biology

Functional and Structural Insight Into the Flexibility of Cytochrome P450 Reductases From Sorghum Bicolor and Its Implications for Lignin Composition. Journal of Biological Chemistry (2022)

Bixia ZhangGerhard R. MunskeVitaliy I. TimokhinJohn RalphDmitri R. DavydovWilfred VermerrisScott E. SattlerChulHee Kang

medicinal chemistryfunctional selectivityplant physiologybiological chemistrycell and molecular biologybiochemistryplant biotechnologyplant geneticssorghum bicolorenzymesplant sciencebotanymembrane biologylignin compositionplant metabolismplant biochemistrybiological engineeringstructural insightredox biologybiological inorganic chemistrymolecular biology

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Dmitri Davydov

Research Professor

Washington State University

Affiliations

College of Arts and Sciences

Department of Chemistry

Dmitri Davydov is currently serving as a College Of Arts And Sciences Research Professor at Washington State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Dmitri Davydov

Washington State University

Research Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Differential Tissue Abundance of Membrane-Bound Drug Metabolizing Enzymes and Transporter Proteins by Global Proteomics. Drug Metabolism and Disposition (2024)

Dilip Kumar SinghDeepak AhireDmitri R. DavydovBhagwat Prasad

Effects of Alcohol Consumption and Tobacco Smoking on the Composition of the Ensemble of Drug Metabolizing Enzymes and Transporters in Human Liver. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Kari A. GaitherDilip Kumar SinghGuihua YueJulia TrudeauKannapiran PonrajNadezhda Y. DavydovaPhilip LazarusDmitri R. DavydovBhagwat Prasad

Interplay of Alcohol Intake, Smoking, and Sex on the Protein Abundance of Hepatic Drug Metabolizing Enzymes and Transporters in Humans. (2024)

Kari GaitherDilip K. SinghGuihua E. YueJulia TrudeauKannapiran PonrajPhilip LazarusDmitri R. DavydovBhagwat Prasad

Kannapiran PonrajKari A GaitherDilip Kumar SinghNadezhda DavydovaMengqi ZhaoShaman LuoPhillip LazarusBhagwat PrasadDmitri R Davydov

alcohol consumptionpharmacologypharmacokineticsdrug metabolismmolecular biologymetabolismbiochemistry

Non-Additivity of the Functional Properties of P450 Enzymes in the Human Drug-Metabolizing Ensemble Revealed in a Study With a Series of Individual Microsomal Preparations. (2024)

Kannapiran PonrajKari GaitherDilip K. SinghBhagwat PrasadDmitri R. Davydov

pharmacologydrug metabolismhuman drug-metabolizing ensembleenzymesmolecular biologymetabolism

Quantitative Proteomics Identifies Significant Changes in the Abundance and Composition of Hepatic Drug Metabolizing Enzymes in Heavy Alcohol Drinkers. Drug Metabolism and Pharmacokinetics (2024)

Kari GaitherDilip Kumar SinghGuihua YueJulia TrudeauNadezhda DavydovaDmitri R. DavydovPhilip LazarusBhagwat Prasad

medicinal chemistrymedicineproteomicspharmacologypharmacokineticsdrug metabolismenzymeshepatologypathologyheavy alcohol drinkers

High-Throughput Assay of Cytochrome P450-Dependent Drug Demethylation Reactions and Its Use to Re-Evaluate the Pathways of Ketamine Metabolism. Biology (2023)

Nadezhda Y. DavydovaDavid A. HutnerKari A. GaitherDilip Kumar SinghBhagwat PrasadDmitri R. Davydov

immunologypharmacologydrug metabolismketamine metabolismhigh-throughput assaypathway analysisneuroscience

Conformational Rearrangements in the Redox Cycling of Nadph-Cytochrome P450 Reductase From Sorghum Bicolor Explored With Fret and Pressure-Perturbation Spectroscopy. Biology (2022)

Bixia ZhangChulHee KangDmitri R. Davydov

sorghum bicolorenzymesmolecular biologyconformational rearrangementsredox cyclingpressure-perturbation spectroscopyprotein sciencebiochemistry

Exploring the Interactome of Cytochrome P450 2E1 in Human Liver Microsomes With Chemical Crosslinking Mass Spectrometry. Biomolecules (2022)

Dmitri R. DavydovBikash DangiGuihua YueDeepak S. AhireBhagwat PrasadVictor G. Zgoda

biomolecular interactionspharmacologyinteractomicshuman liver microsomesmolecular biologymass spectrometrycell biology

Functional and Structural Insight Into the Flexibility of Cytochrome P450 Reductases From Sorghum Bicolor and Its Implications for Lignin Composition. Journal of Biological Chemistry (2022)

Bixia ZhangGerhard R. MunskeVitaliy I. TimokhinJohn RalphDmitri R. DavydovWilfred VermerrisScott E. SattlerChulHee Kang

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