Faculty

Institution

Unit

Venue

Bruce Demple

Professor

Stony Brook University

Affiliations

Renaissance School of Medicine

Pharmacological Sciences

Bruce Demple is currently serving as a Pharmacological Sciences Professor at Stony Brook University.

Honors

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Experiences

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Education

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Bruce Demple

Stony Brook University

Professor

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molecular biology genetics dna repair biochemistry gene expression redox biology microbiology protein science enzymes membrane biology biological chemistry oxidative stress structural biology bacteriology microbial genetics free radical biology escherichia coli gene regulation molecular microbiology transcription regulation clinical microbiology molecular genetics genome biology nucleic acids molecular regulation epigenetics mammalian biology rna biology molecular physiology mutagenesis molecular cell biology structural molecular biology molecular science microbial physiology redox signaling gene function human apurinic endonuclease enzyme inhibition yeast applied microbiology biological inorganic chemistry functional modification cancer biology nitric oxide biochemical sciences gene editing medical microbiology cancer genetics cell death molecular research antibiotic resistance biochemical genetics cell regulation oxidative stress genes genome instability functional regulation protein expression molecular biotechnology nucleic acid amplification molecular substrates biomolecular interactions apoptosis oxidative dna damage transcriptional activation genetic responses nitric oxide toxicity oxidative damage host-guest chemistry veterinary microbiology positive control hydrogen peroxide iron-sulfur centers soxr transcription activator exonuclease iii gene control soxr protein dna repair pathways molecular metabolism

Notable Scholarly Works

Notable Federal Grants

Collaborators

Artificial Space Weathering to Mimic Solar Wind Enhances the Toxicity of Lunar Dust Simulants in Human Lung Cells. GeoHealth (2024)

J. H. M. ChangZ. XueJ. BauerB. WehleD. A. HendrixT. CatalanoJ. A. HurowitzH. NekvasilB. Demple

toxicologysolar windspace environmentspace sciencespace weatherlunar dust simulantshuman lung cellshealth sciencesplanetary sciences

C-Terminal Residues of Dna Polymerase β and E3 Ligase Required for Ubiquitin-Linked Proteolysis of Oxidative Dna-Protein Crosslinks. DNA repair (2024)

Jason L. QuiñonesMeiyi TangQingming FangRobert W. SobolBruce Demple

ubiquitin-linked proteolysisbiochemistryc-terminal residuesoxidative dna-protein crosslinksdna repair

Intraluminal Vesicle Trafficking is Involved in the Secretion of Base Excision Repair Protein Ape1. FEBS Journal (2024)

Isabella ParoliniMonica DegrassiFrancesca SpadaroFederica CaponnettoKatia FecchiSerena MastantuonoXue ZhouyiyuanBruce DempleDaniela CesselliGianluca Tell

neurologyphysiologyprotein secretionintraluminal vesicle traffickingneurosciencecell traffickingmembrane biologyprotein transportdevelopmental neurobiology

Author Response for"Intraluminal Vesicle Trafficking is Involved in the Secretion of Base Excision Repair Protein Scp Ape1 /Scp". (2023)

None Isabella ParoliniNone Monica DegrassiNone Francesca SpadaroNone Federica CaponnettoNone Katia FecchiNone Serena MastantuonoNone Xue ZhouyiyuanNone Bruce DempleNone Daniela CesselliNone Gianluca Tell

neurologyprotein secretionintraluminal vesicle traffickingneurosciencemembrane biologyprotein transportpharmacologymolecular neuroscienceauthor response

Maintenance of Flap Endonucleases for Long-Patch Base Excision Dna Repair in Mouse Muscle and Neuronal Cells Differentiated in Vitro. International Journal of Molecular Sciences (2023)

Rachel A. CastonPaola FortiniKevin ChenJack BauerEugenia DogliottiY. Whitney YinBruce Demple

genetic engineeringmouse muscleanimal physiologycellular differentiationneuronal cellsmuscle functionanimal biotechnologyflap endonucleasesneurosciencemolecular sciencemammalian biologymolecular biologyskeletal musclemolecular neurosciencegene expressiondna repairgenetics

Knockout and Inhibition of Ape1: Roles of Ape1 in Base Excision Dna Repair and Modulation of Gene Expression. Antioxidants (2022)

Zhouyiyuan XueBruce Demple

apoptosisredox biologyfree radical biologyavian biologygene regulationpharmacologymolecular biologyoxidative stressgene expressiondna repairantioxidantsgenetics

Dna Repair | Dna Base Excision Repair Pathways. Elsevier eBooks (2021)

Upasna ThaparBruce Demple

dna repairmolecular biology

Mitochondrial Dysfunction and Genotoxicity Provoked by Exposure of Human Lung Cells to Lunar Dust Simulants. LPICo (2020)

J. H. M. ChangK. ChenD. HendrixT. CatalanoJ. A. HurowitzH. NekvasilB. Demple

neurologytoxicologymitochondrial dysfunctionliver physiologyinhalation toxicologyphysiologycell biologyrespiratory medicinehuman lung cells

Oxidative Dna-Protein Crosslinks Formed in Mammalian Cells by Abasic Site Lyases Involved in Dna Repair. DNA repair (2020)

Jason L. QuiñonesUpasna ThaparSamuel H. WilsonDale A. RamsdenBruce Demple

biological engineeringmammalian cellsmolecular biologyoxidative stressoxidative dna-protein crosslinksmammalian biologydna repairbiomolecular engineeringabasic site lyases

Deployment of Dna Polymerases Beta and Lambda in Single-Nucleotide and Multinucleotide Pathways of Mammalian Base Excision Dna Repair. DNA repair (2019)

Upasna ThaparBruce Demple

biological engineeringdna repairmolecular biologygenetics

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Bruce Demple

Professor

Stony Brook University

Affiliations

Renaissance School of Medicine

Pharmacological Sciences

Bruce Demple is currently serving as a Pharmacological Sciences Professor at Stony Brook University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Bruce Demple

Stony Brook University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Artificial Space Weathering to Mimic Solar Wind Enhances the Toxicity of Lunar Dust Simulants in Human Lung Cells. GeoHealth (2024)

J. H. M. ChangZ. XueJ. BauerB. WehleD. A. HendrixT. CatalanoJ. A. HurowitzH. NekvasilB. Demple

toxicologysolar windspace environmentspace sciencespace weatherlunar dust simulantshuman lung cellshealth sciencesplanetary sciences

C-Terminal Residues of Dna Polymerase β and E3 Ligase Required for Ubiquitin-Linked Proteolysis of Oxidative Dna-Protein Crosslinks. DNA repair (2024)

Jason L. QuiñonesMeiyi TangQingming FangRobert W. SobolBruce Demple

ubiquitin-linked proteolysisbiochemistryc-terminal residuesoxidative dna-protein crosslinksdna repair

Intraluminal Vesicle Trafficking is Involved in the Secretion of Base Excision Repair Protein Ape1. FEBS Journal (2024)

Isabella ParoliniMonica DegrassiFrancesca SpadaroFederica CaponnettoKatia FecchiSerena MastantuonoXue ZhouyiyuanBruce DempleDaniela CesselliGianluca Tell

neurologyphysiologyprotein secretionintraluminal vesicle traffickingneurosciencecell traffickingmembrane biologyprotein transportdevelopmental neurobiology

Author Response for"Intraluminal Vesicle Trafficking is Involved in the Secretion of Base Excision Repair Protein Scp Ape1 /Scp". (2023)

neurologyprotein secretionintraluminal vesicle traffickingneurosciencemembrane biologyprotein transportpharmacologymolecular neuroscienceauthor response

Maintenance of Flap Endonucleases for Long-Patch Base Excision Dna Repair in Mouse Muscle and Neuronal Cells Differentiated in Vitro. International Journal of Molecular Sciences (2023)

Rachel A. CastonPaola FortiniKevin ChenJack BauerEugenia DogliottiY. Whitney YinBruce Demple

Knockout and Inhibition of Ape1: Roles of Ape1 in Base Excision Dna Repair and Modulation of Gene Expression. Antioxidants (2022)

Zhouyiyuan XueBruce Demple

apoptosisredox biologyfree radical biologyavian biologygene regulationpharmacologymolecular biologyoxidative stressgene expressiondna repairantioxidantsgenetics

Dna Repair | Dna Base Excision Repair Pathways. Elsevier eBooks (2021)

Upasna ThaparBruce Demple

dna repairmolecular biology

Mitochondrial Dysfunction and Genotoxicity Provoked by Exposure of Human Lung Cells to Lunar Dust Simulants. LPICo (2020)

J. H. M. ChangK. ChenD. HendrixT. CatalanoJ. A. HurowitzH. NekvasilB. Demple

neurologytoxicologymitochondrial dysfunctionliver physiologyinhalation toxicologyphysiologycell biologyrespiratory medicinehuman lung cells

Oxidative Dna-Protein Crosslinks Formed in Mammalian Cells by Abasic Site Lyases Involved in Dna Repair. DNA repair (2020)

Jason L. QuiñonesUpasna ThaparSamuel H. WilsonDale A. RamsdenBruce Demple

biological engineeringmammalian cellsmolecular biologyoxidative stressoxidative dna-protein crosslinksmammalian biologydna repairbiomolecular engineeringabasic site lyases

Deployment of Dna Polymerases Beta and Lambda in Single-Nucleotide and Multinucleotide Pathways of Mammalian Base Excision Dna Repair. DNA repair (2019)

Upasna ThaparBruce Demple

biological engineeringdna repairmolecular biologygenetics

1
2
3
4
5
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10 / page

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Similar Faculty Members

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics

Stanley N. Cohen

Institution

Stanford University

molecular biology

mutagenesis (molecular biology technique)

Max Costa

Institution

New York University

molecular biology

epigenetics

Neil Osheroff

Institution

Vanderbilt University

dna sequencing

molecular biology

Graham C. Walker

Institution

Massachusetts Institute of Technology

molecular biology

mutagenesis

Phillip Hylemon

Institution

Virginia Commonwealth University

digestive tract

dysbiosis

Leona D. Samson

Institution

Massachusetts Institute of Technology

genetics

molecular biology

George Stark

Institution

Case Western Reserve University

molecular biology

immunology

Lawrence J. Marnett

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Vanderbilt University

anti-inflammatory agent

biochemistry

Anthony E. Pegg

Institution

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cancer letter

toxicological mechanism