Faculty

Institution

Unit

Venue

Dehua Pei

Professor

Ohio State University

Affiliations

College of Arts and Sciences

Chemistry and Biochemistry

Dehua Pei is currently serving as a Chemistry And Biochemistry Professor at Ohio State University.

Honors

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Experiences

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Education

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Dehua Pei

Ohio State University

Professor

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pharmacology biochemistry enzymes molecular biology medicinal chemistry drug discovery protein science biomolecular engineering enzyme inhibition structural biology membrane biology peptides medicinal research protein structure peptide deformylase peptide synthesis chemical biology drug targeting peptide science peptide library bioorganic chemistry peptide engineering enzyme catalysis combinatorial chemistry protein chemistry biological chemistry structural molecular biology rational drug design pharmaceutical chemistry protein synthesis substrate specificity catalytic mechanism cyclic peptides protein tyrosine phosphatases molecular substrates biocatalysis high-throughput screening sequence specificity combinatorial library partial edman degradation combinatorial libraries combinatorial peptide library cell-penetrating peptides coordination chemistry redox biology clinical microbiology virus research mammalian biology biomolecular structure enzyme specificity combinatorial methods host specificity cyclic cell-penetrating peptide cyclic peptidyl inhibitors duplex dna peptide deformylase inhibitors peptidyl aldehydes transition metal chemistry molecular structure environmental microbiology biological inorganic chemistry protein purification protein expression chemical biotechnology molecular regulation biomolecular interactions molecular microbiology molecular catalysis combinatorial designs molecular pharming viral structural protein bioconjugation drug development analytic combinatorics disease gene identification yeast organic chemistry biochemical interaction systems biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bismuth-Cyclized Cell-Penetrating Peptides. Molecular Pharmaceutics (2024)

Jeremy L. RitcheyLindsi FilippiDavis BallardDehua Pei

pharmaceutical chemistrypeptide engineeringpeptide therapeuticspeptide sciencepeptide synthesisbismuth-cyclized cell-penetrating peptidespeptidesmolecular biologypharmacologymolecular pharmacology

Cell-Penetrating Peptides for Sustainable Agriculture. Trends in Plant Science (2024)

Preeti PatelKyle BenzleDehua PeiGuo-Liang Wang

biological engineeringpeptide engineeringcell-penetrating peptidespeptide therapeuticspeptide sciencepeptidesbiotechnologyagricultural biotechnologypeptide library

Cell-Penetrating Peptides Translocate Across the Plasma Membrane by Inducing Vesicle Budding and Collapse. Journal of the American Chemical Society (2024)

Ashweta SahniJeremy L. RitcheyZiqing QianDehua Pei

vascular biologycell-penetrating peptidesvesicle buddingcell biologybiochemistryintracellular traffickingchemical biologymembrane biologymembranesmolecular biologyprotein transportplasma membrane

Design and Synthesis of Peptide Modulators of GαI/S Proteins. Proceedings of the 35th European Peptide Symposium (2024)

Anna PepanianSabriye AydoğduF. Ayberk BinbayPradipta GhoshDehua PeiDiana Imhof

protein designpeptide sciencepeptide synthesisbiochemistrypeptidesprotein synthesispeptide modulators

Design of Target Specific Peptide Inhibitors Using Generative Deep Learning and Molecular Dynamics Simulations. Nature Communications (2024)

Sijie ChenTong LinRuchira BasuJeremy RitcheyShen WangYichuan LuoXingcan LiDehua PeiLevent Burak KaraXiaolin Cheng

peptide engineeringdrug targetingimmunologymedicinal chemistryrational drug designpharmacologydesigndrug discoverygenerative deep learningmolecular dynamics simulations

Design, Synthesis, and Analysis of Macrobicyclic Peptides for Targeting the GαI Protein. Journal of Peptide Science (2024)

Anna PepanianF. Ayberk BinbayDehua PeiDiana Imhof

gai proteinpeptide engineeringprotein designpeptide sciencepeptide synthesisprotein engineeringmacrobicyclic peptidesbiomolecular engineering

Target Specific Peptide Design Using Latent Space Approximate Trajectory Collector. Research Square (2024)

Tong LinSijie ChenRuchira BasuDehua PeiXiaolin ChengLevent Burak Kara

research designdesign researchbiomolecular engineering

The Calcineurin–Nfatc Pathway Modulates the Lipid Mediators in Bal Fluid Extracellular Vesicles, Thereby Regulating Microvascular Endothelial Cell Barrier Function. Frontiers in Physiology (2024)

Manjula KarpurapuYunjuan NieSangwoon ChungJiasheng YanPatrick DoughertySonal PannuJon WislerRyan HarklessNarasimham ParinandiEvgeny BerdyshevDehua PeiJohn W. Christman

liver physiologycalcineurin-nfatc pathwaycell physiologyphysiological researchvascular biologylipid mediatorsphysiologyanatomycell biologyhuman physiologyangiogenesiscellular physiologytranslational physiologysystems biologytissue engineeringprotein sciencehuman biologymolecular physiologymembrane biologymembranes

Bicyclic Peptide Library Screening for the Identification of GαI Protein Modulators. Journal of Medicinal Chemistry (2023)

Anna PepanianFurkan Ayberk BinbaySuchismita RoyBritta NubbemeyerAmritendu KoleyCurran A. RhodesHermann AmmerDehua PeiPradipta GhoshDiana Imhof

gai protein modulatorsmedicinal chemistrypharmacologydrug discoverypeptide library

Cni-103, a Cell Permeable Peptide Inhibitor of the Calcineurin, Alters the Composition and Function of Extracellular Vesicles in Mouse Bronchoalveolar Lavage Fluid During Acute Lung Injury. (2023)

M. KarpurapuK. MaddipatiN. ParinandiE. BerdyshevS. ChungD. PeiJ.W. Christman

respiratory neurobiologyneurosciencepharmacologytherapeutic targetsenzymespeptide therapeuticscell biologypeptidespulmonary pharmacologyacute lung injurymembrane proteinsrespiratory medicineprotein functionfunctional modificationextracellular vesiclesmolecular physiologymembrane biologysignal transductionmammalian biologyenzyme inhibition

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Dehua Pei

Professor

Ohio State University

Affiliations

College of Arts and Sciences

Chemistry and Biochemistry

Dehua Pei is currently serving as a Chemistry And Biochemistry Professor at Ohio State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Dehua Pei

Ohio State University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bismuth-Cyclized Cell-Penetrating Peptides. Molecular Pharmaceutics (2024)

Jeremy L. RitcheyLindsi FilippiDavis BallardDehua Pei

pharmaceutical chemistrypeptide engineeringpeptide therapeuticspeptide sciencepeptide synthesisbismuth-cyclized cell-penetrating peptidespeptidesmolecular biologypharmacologymolecular pharmacology

Cell-Penetrating Peptides for Sustainable Agriculture. Trends in Plant Science (2024)

Preeti PatelKyle BenzleDehua PeiGuo-Liang Wang

biological engineeringpeptide engineeringcell-penetrating peptidespeptide therapeuticspeptide sciencepeptidesbiotechnologyagricultural biotechnologypeptide library

Cell-Penetrating Peptides Translocate Across the Plasma Membrane by Inducing Vesicle Budding and Collapse. Journal of the American Chemical Society (2024)

Ashweta SahniJeremy L. RitcheyZiqing QianDehua Pei

vascular biologycell-penetrating peptidesvesicle buddingcell biologybiochemistryintracellular traffickingchemical biologymembrane biologymembranesmolecular biologyprotein transportplasma membrane

Design and Synthesis of Peptide Modulators of GαI/S Proteins. Proceedings of the 35th European Peptide Symposium (2024)

Anna PepanianSabriye AydoğduF. Ayberk BinbayPradipta GhoshDehua PeiDiana Imhof

protein designpeptide sciencepeptide synthesisbiochemistrypeptidesprotein synthesispeptide modulators

Design of Target Specific Peptide Inhibitors Using Generative Deep Learning and Molecular Dynamics Simulations. Nature Communications (2024)

Sijie ChenTong LinRuchira BasuJeremy RitcheyShen WangYichuan LuoXingcan LiDehua PeiLevent Burak KaraXiaolin Cheng

peptide engineeringdrug targetingimmunologymedicinal chemistryrational drug designpharmacologydesigndrug discoverygenerative deep learningmolecular dynamics simulations

Design, Synthesis, and Analysis of Macrobicyclic Peptides for Targeting the GαI Protein. Journal of Peptide Science (2024)

Anna PepanianF. Ayberk BinbayDehua PeiDiana Imhof

gai proteinpeptide engineeringprotein designpeptide sciencepeptide synthesisprotein engineeringmacrobicyclic peptidesbiomolecular engineering

Target Specific Peptide Design Using Latent Space Approximate Trajectory Collector. Research Square (2024)

Tong LinSijie ChenRuchira BasuDehua PeiXiaolin ChengLevent Burak Kara

research designdesign researchbiomolecular engineering

The Calcineurin–Nfatc Pathway Modulates the Lipid Mediators in Bal Fluid Extracellular Vesicles, Thereby Regulating Microvascular Endothelial Cell Barrier Function. Frontiers in Physiology (2024)

Manjula KarpurapuYunjuan NieSangwoon ChungJiasheng YanPatrick DoughertySonal PannuJon WislerRyan HarklessNarasimham ParinandiEvgeny BerdyshevDehua PeiJohn W. Christman

Bicyclic Peptide Library Screening for the Identification of GαI Protein Modulators. Journal of Medicinal Chemistry (2023)

Anna PepanianFurkan Ayberk BinbaySuchismita RoyBritta NubbemeyerAmritendu KoleyCurran A. RhodesHermann AmmerDehua PeiPradipta GhoshDiana Imhof

gai protein modulatorsmedicinal chemistrypharmacologydrug discoverypeptide library

Cni-103, a Cell Permeable Peptide Inhibitor of the Calcineurin, Alters the Composition and Function of Extracellular Vesicles in Mouse Bronchoalveolar Lavage Fluid During Acute Lung Injury. (2023)

M. KarpurapuK. MaddipatiN. ParinandiE. BerdyshevS. ChungD. PeiJ.W. Christman

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