Faculty

Institution

Unit

Venue

Dara W. Frank

Professor

Medical College of Wisconsin

Affiliations

Center for Infectious Disease Research

Graduate School

Microbiology & Immunology

Dara W. Frank is currently serving as a Center For Infectious Disease Research Professor at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Dara W. Frank

Medical College of Wisconsin

Professor

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microbiology microbial pathogenesis immunology molecular biology bacteria pathogenic bacteria clinical microbiology infectious diseases pathogens infection control bacteriology molecular microbiology virulence factors enzymes protein science microbial genetics gene expression applied microbiology environmental microbiology antimicrobial resistance respiratory medicine vascular biology pseudomonas aeruginosa innate immune system cellular physiology molecular physiology immune responses toxins structural molecular biology microbial physiology infectious respiratory disease respiratory infections microbial disease protein secretion medical microbiology biological chemistry biomolecular structure endothelial dysfunction microbial toxins enzyme inhibition cell death cellular immune responses host response hospital infections transcription regulation pathogen transmission clinical infection inhibitory activity francisella tularensis specific resistance viral pathogenesis pathogen detection antigen processing molecular immunology pathogen characterization key site host factors veterinary microbiology mutagenesis adaptive immune system toxinology biochemical interaction lung injury alveolar epithelial injury trans-regulatory locus eukaryotic cells bacterial effectors conformational changes epithelial injury exou expression acute cytotoxicity adenylate cyclase lower respiratory passive immunization antigen protects type iii intoxication bacterial toxins lung transplant

Notable Scholarly Works

Notable Federal Grants

Collaborators

Filamentous-Actin as a Determinant of Exoy-Induced Purine and Pyrimidine Cyclic Nucleotide Monophosphate Signaling in Pulmonary Microvascular Endothelium. Physiology (2025)

vascular biologycirculatory physiologyphysiologycell signalingblood vesselscell biologycellular physiologypulmonary circulationendothelial dysfunctionmolecular physiologycytoskeletonpulmonary vascular diseaseexoy-induced purinesignal transductioncellular biochemistrypulmonary microvascular endothelium

Pseudomonas Aeruginosa Infection Induces Intragraft Lymphocytotoxicity That Triggers Lung Transplant Antibody-Mediated Rejection. Science Translational Medicine (2025)

Fuyi LiaoDequan ZhouMarlene CanoZhiyi LiuDavide ScozziLaneshia K. TagueDerek E. ByersWenjun LiJothilingam SivapackiamVijay SharmaAlexander S. KrupnickDara W. FrankDaniel KreiselHrishikesh S. KulkarniRamsey R. HachemAndrew E. Gelman

graft rejectionimmunologytransplantation medicineclinical microbiologyinfectious diseasesinfectious respiratory diseaseantibiotic resistancehospital infectionspathogenstransplant infectious diseasespathogenic bacteriatranslational medicinemicrobiologyenvironmental microbiologytransplant antibody-mediated rejectionlung transplantationmicrobial pathogenesiscell transplantationantimicrobial resistance

Pseudomonas Aeruginosa Infection Induces Intragraft Lymphocytotoxicity That Triggers Lung Transplant Antibody-Mediated Rejection. Sci Transl Med (2025)

transplant infectious diseasesinfectious diseasespathogenic bacterialung transplantationimmunologygraft rejectioninfection inducesmedicineclinical transplantationtransplant antibody-mediated rejectionmicrobial pathogenesis

Pseudomonas Aeruginosa Toxin Exoy Inhibits Sirt-1 Mediated Autophagy to Promote Pulmonogenic Tauopathy. American Journal of Respiratory and Critical Care Medicine (2025)

K. PankratzZ. DickeyA. PhamR. MorrowK.A. MorrowT. StevensD. FrankK. PatelM. LipsmeyerK. Michalak

infectious diseasesinfectious respiratory diseaserespiratory infectionspathogenic bacteriarespiratory medicinemicrobiologypathogensautophagypulmonogenic tauopathycritical careinfection controlmicrobial pathogenesis

Cump Elicits Inter-Endothelial Gap Formation During Pseudomonas Aeruginosa Infection. AJP Lung Cellular and Molecular Physiology (2024)

Althea deWeeverSunita S. PaudelChun ZhouC. Michael FrancisDhananjay T. TambeDara W. FrankRon BalczonTroy Stevens

infectious diseasesinfectious respiratory diseasecell biologycellular physiologymicrobiologymolecular physiologyinter-endothelial gap formationmicrobial pathogenesis

Cump Elicits Interendothelial Gap Formation During Pseudomonas Aeruginosa Infection. Am J Physiol Lung Cell Mol Physiol (2024)

vascular biologyinfectious diseasespathogenic bacteriapathogenesisinterendothelial gap formationmicrobiologybacterialung microbiomevirulence factorsbacteriologyinfection controlmicrobial pathogenesis

Residues Within the Lptc Transmembrane Helix Are Critical for Escherichia Coli Lptb2 Fg Atpase Regulation. Protein Sci (2024)

lptc transmembrane helixenzymesprotein sciencebiomolecular structuremembrane proteinsbiochemistrymolecular biologyprotein structurestructural molecular biologymolecular researchstructural biologyprotein biosynthesis

Binding and Transport of Lps Occurs Through the Coordinated Combination of an Array of Sites Across the Entire Escherichia Coli Lps Transport Protein Lpta. Protein Sci (2023)

biological macromoleculesprotein sciencemolecular microbiologymembrane proteinsbiochemistryprotein assemblyprotein transportbiochemical sciencesmolecular biologyprotein structurebiomolecular interactionsmulti-protein assemblystructural molecular biologystructural biologycoordinated combination

Binding and Transport of Lps Occurs Through the Coordinated Combination of an Array of Sites Across the Entire Escherichia Coli Lps Transport Protein Lpta.. Protein Sci. (2023)

biological macromoleculesprotein sciencemolecular microbiologymembrane proteinsbiochemistrybacteriaprotein transportbiochemical sciencesmolecular biologybiological chemistryprotein structurebiomolecular interactionsmulti-protein assemblystructural molecular biologyprotein assemblycoordinated combination

Binding and Transport of Lps Occurs Through the Coordinated Combination of an Array of Sites Across the Entire Escherichia Coli Lps Transport Protein Lpta. Protein Science (2023)

Kathryn M. SchultzJohn R. SchneiderMatthew A. FischerNicholas P. CinaMolly O. RiegertDara W. FrankCandice S. Klug

biophysicsprotein sciencebiochemistryintracellular traffickingprotein transportmolecular biologyprotein structure

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Dara W. Frank

Professor

Medical College of Wisconsin

Affiliations

Center for Infectious Disease Research

Graduate School

Microbiology & Immunology

Dara W. Frank is currently serving as a Center For Infectious Disease Research Professor at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Dara W. Frank

Medical College of Wisconsin

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Filamentous-Actin as a Determinant of Exoy-Induced Purine and Pyrimidine Cyclic Nucleotide Monophosphate Signaling in Pulmonary Microvascular Endothelium. Physiology (2025)

Pseudomonas Aeruginosa Infection Induces Intragraft Lymphocytotoxicity That Triggers Lung Transplant Antibody-Mediated Rejection. Science Translational Medicine (2025)

Pseudomonas Aeruginosa Infection Induces Intragraft Lymphocytotoxicity That Triggers Lung Transplant Antibody-Mediated Rejection. Sci Transl Med (2025)

Pseudomonas Aeruginosa Toxin Exoy Inhibits Sirt-1 Mediated Autophagy to Promote Pulmonogenic Tauopathy. American Journal of Respiratory and Critical Care Medicine (2025)

K. PankratzZ. DickeyA. PhamR. MorrowK.A. MorrowT. StevensD. FrankK. PatelM. LipsmeyerK. Michalak

Cump Elicits Inter-Endothelial Gap Formation During Pseudomonas Aeruginosa Infection. AJP Lung Cellular and Molecular Physiology (2024)

Althea deWeeverSunita S. PaudelChun ZhouC. Michael FrancisDhananjay T. TambeDara W. FrankRon BalczonTroy Stevens

infectious diseasesinfectious respiratory diseasecell biologycellular physiologymicrobiologymolecular physiologyinter-endothelial gap formationmicrobial pathogenesis

Cump Elicits Interendothelial Gap Formation During Pseudomonas Aeruginosa Infection. Am J Physiol Lung Cell Mol Physiol (2024)

vascular biologyinfectious diseasespathogenic bacteriapathogenesisinterendothelial gap formationmicrobiologybacterialung microbiomevirulence factorsbacteriologyinfection controlmicrobial pathogenesis

Residues Within the Lptc Transmembrane Helix Are Critical for Escherichia Coli Lptb2 Fg Atpase Regulation. Protein Sci (2024)

Binding and Transport of Lps Occurs Through the Coordinated Combination of an Array of Sites Across the Entire Escherichia Coli Lps Transport Protein Lpta. Protein Sci (2023)

Binding and Transport of Lps Occurs Through the Coordinated Combination of an Array of Sites Across the Entire Escherichia Coli Lps Transport Protein Lpta.. Protein Sci. (2023)

Binding and Transport of Lps Occurs Through the Coordinated Combination of an Array of Sites Across the Entire Escherichia Coli Lps Transport Protein Lpta. Protein Science (2023)

Kathryn M. SchultzJohn R. SchneiderMatthew A. FischerNicholas P. CinaMolly O. RiegertDara W. FrankCandice S. Klug

biophysicsprotein sciencebiochemistryintracellular traffickingprotein transportmolecular biologyprotein structure

1
2
3
4
5
15
10 / page

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