Faculty

Institution

Unit

Venue

Joseph T. Barbieri, PhD

Professor Microbiology & Immunology; Associate Director Medical Scientist Training Program

Medical College of Wisconsin

Affiliations

Center for Infectious Disease Research

Center for Microbiome Research

Enzymology and Metabolism

Medical Scientist Training Program

Microbiology & Immunology

Joseph T. Barbieri, Phd is currently serving as a Center For Infectious Disease Research Professor Microbiology & Immunology; Associate Director Medical Scientist Training Program at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Joseph T. Barbieri, PhD

Medical College of Wisconsin

Professor Microbiology & Immunology; Associate Director Medical Scientist Training Program

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microbiology biochemistry molecular biology immunology toxins microbial pathogenesis infection control clinical microbiology toxinology enzymes bacteria pathogens biological chemistry pathogenic bacteria protein science microbial toxins enzyme inhibition immune responses toxicology pertussis toxin molecular microbiology structural biology virulence factors applied microbiology botulinum neurotoxin structural molecular biology vaccine research peptides innate immune system intracellular trafficking diphtheria toxin botulinum neurotoxins environmental microbiology medicinal research peptide science biomolecules microbial genetics antigen processing vaccine development inhibitory activity receptor (biochemistry) bacteriology neuropeptides protein expression protein purification vaccine design escherichia coli bacterial toxins biomolecular structure biomolecular interactions protein biosynthesis biocatalysis type iii cytotoxin general virology virus research enzyme specificity molecular immunology host response medical microbiology enzyme catalysis actin cytoskeleton eukaryotic cells epithelial cells pseudomonas aeruginosa tetanus neurotoxin host specificity treatment and prevention biochemical interaction microbial disease microbial physiology gene structure biochemical genetics substrate recognition functional domains mammalian cells botulinum toxin infectious diseases

Notable Scholarly Works

Notable Federal Grants

Collaborators

Botulinum Neurotoxin Light Chain/A1 Uses Fast Synaptic Vesicle Cycling to Cleave Plasma Membrane Bound Snap-25. Communications Biology (2025)

biophysicsmolecular neurodegenerationprotein secretionneuronscell biologymembrane proteinscellular physiologycellular structureintracellular traffickingsynaptic vesicle cyclingmembrane biologymolecular cell biologyprotein transportmolecular biologysignal transductionplasma membranecellular biochemistry

Nontoxic, Multi-Domain Botulinum Neurotoxin-Lchcn as Vaccines Against Botulism.. Vaccine (2025)

vaccine designinfectious diseasesvaccinesvaccinationimmunologyimmunotherapytoxinsvaccine researchcommunicable diseasesmulti-domain botulinumtherapeutic vaccinesinfection control

Potency Evaluations of Recombinant Botulinum Neurotoxin A1 Mutants Designed to Reduce Toxicity. International Journal of Molecular Sciences (2024)

Polrit ViravathanaWilliam H. TeppMarite BradshawAmanda PrzedpelskiJoseph T. BarbieriSabine Pellett

toxicologyneuropharmacologytoxinologymolecular sciencetoxinspotency evaluationspharmacologymolecular biologybiomolecular engineering

Toxicity Evaluations of Botulinum Neurotoxin A1 Mutants Designed to Be Atoxic. Toxicon (2024)

Polrit ViravathanaWilliam H. TeppMarite BradshawEric A. JohnsonJoseph T. BarbieriSabine Pellett

neurologytoxicity evaluationstoxicology

Botulinum Neurotoxin A4 Has a 1000-Fold Reduced Potency Due to Three Single Amino Acid Alterations in the Protein Receptor Binding Domain. International Journal of Molecular Sciences (2023)

William H. TeppMarite BradshawAlexander P. GardnerRebecca L. KaufmanJoseph T. BarbieriSabine Pellett

neurologyprotein scienceneurosciencemolecular sciencemolecular biologymolecular neuroscience

Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines. Vaccines (2023)

Davide OldriniRoberta Di BenedettoMartina CarducciDaniele De SimoneLuisa MassaiRenzo AlfiniBarbara GalliBrunella BrunelliAmanda PrzedpelskiJoseph T. BarbieriOmar RossiCarlo GiannelliRino RappuoliFrancesco BertiFrancesca Micoli

vaccine designvaccinescarrier proteinvaccine developmentimmunologyvaccinationtetanus toxoidvaccine researchrecombinant formglycoconjugate vaccines

Genetically Detoxified Tetanus Toxin as a Vaccine and Conjugate Carrier Protein. Vaccine (2022)

Min-Ju ChangMorgane Ollivault-ShiflettRichard SchumanSon Ngoc NguyenIgor A. KaltashovCedric BobstShalini P. RajagopalAmanda PrzedpelskiJoseph T. BarbieriAndrew Lees

vaccine designconjugate carrier proteinvaccinesvaccine developmentvaccine safetyimmunologyvaccinationvaccine researchtetanus toxinvaccine testinggenetics

How Botulinum Neurotoxin Light Chain A1 Maintains Stable Association With the Intracellular Neuronal Plasma Membrane. Toxins (2022)

Alexander P. GardnerJoseph T. BarbieriSabine Pellett

neurologytoxicologypharmacologyneuroscience

Light Chain Role in Action of Botulinum Toxins/Clostridial Neurotoxins. Springer eBooks (2022)

Alexander GardnerJoseph T. Barbieri

light chain roletoxicologyenzymesphotomedicinetoxinologyneurosciencebiochemistrytoxinsphotobiologyplant toxinsoptical propertiespharmacologyphototropinlight regulationredox biology

Multiple Domains of Staphylococcal Superantigen-Like Protein 11 (Ssl11) Contribute to Neutrophil Inhibition. Biochemistry (2022)

Chen YangJoseph T. BarbieriNancy M. DahmsChen Chen

microbiologyimmune responsesimmunologybiochemistry

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Joseph T. Barbieri, PhD

Professor Microbiology & Immunology; Associate Director Medical Scientist Training Program

Medical College of Wisconsin

Affiliations

Center for Infectious Disease Research

Center for Microbiome Research

Enzymology and Metabolism

Medical Scientist Training Program

Microbiology & Immunology

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Joseph T. Barbieri, PhD

Medical College of Wisconsin

Professor Microbiology & Immunology; Associate Director Medical Scientist Training Program

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Botulinum Neurotoxin Light Chain/A1 Uses Fast Synaptic Vesicle Cycling to Cleave Plasma Membrane Bound Snap-25. Communications Biology (2025)

Nontoxic, Multi-Domain Botulinum Neurotoxin-Lchcn as Vaccines Against Botulism.. Vaccine (2025)

vaccine designinfectious diseasesvaccinesvaccinationimmunologyimmunotherapytoxinsvaccine researchcommunicable diseasesmulti-domain botulinumtherapeutic vaccinesinfection control

Potency Evaluations of Recombinant Botulinum Neurotoxin A1 Mutants Designed to Reduce Toxicity. International Journal of Molecular Sciences (2024)

Polrit ViravathanaWilliam H. TeppMarite BradshawAmanda PrzedpelskiJoseph T. BarbieriSabine Pellett

toxicologyneuropharmacologytoxinologymolecular sciencetoxinspotency evaluationspharmacologymolecular biologybiomolecular engineering

Toxicity Evaluations of Botulinum Neurotoxin A1 Mutants Designed to Be Atoxic. Toxicon (2024)

Polrit ViravathanaWilliam H. TeppMarite BradshawEric A. JohnsonJoseph T. BarbieriSabine Pellett

neurologytoxicity evaluationstoxicology

Botulinum Neurotoxin A4 Has a 1000-Fold Reduced Potency Due to Three Single Amino Acid Alterations in the Protein Receptor Binding Domain. International Journal of Molecular Sciences (2023)

William H. TeppMarite BradshawAlexander P. GardnerRebecca L. KaufmanJoseph T. BarbieriSabine Pellett

neurologyprotein scienceneurosciencemolecular sciencemolecular biologymolecular neuroscience

Testing a Recombinant Form of Tetanus Toxoid as a Carrier Protein for Glycoconjugate Vaccines. Vaccines (2023)

vaccine designvaccinescarrier proteinvaccine developmentimmunologyvaccinationtetanus toxoidvaccine researchrecombinant formglycoconjugate vaccines

Genetically Detoxified Tetanus Toxin as a Vaccine and Conjugate Carrier Protein. Vaccine (2022)

Min-Ju ChangMorgane Ollivault-ShiflettRichard SchumanSon Ngoc NguyenIgor A. KaltashovCedric BobstShalini P. RajagopalAmanda PrzedpelskiJoseph T. BarbieriAndrew Lees

vaccine designconjugate carrier proteinvaccinesvaccine developmentvaccine safetyimmunologyvaccinationvaccine researchtetanus toxinvaccine testinggenetics

How Botulinum Neurotoxin Light Chain A1 Maintains Stable Association With the Intracellular Neuronal Plasma Membrane. Toxins (2022)

Alexander P. GardnerJoseph T. BarbieriSabine Pellett

neurologytoxicologypharmacologyneuroscience

Light Chain Role in Action of Botulinum Toxins/Clostridial Neurotoxins. Springer eBooks (2022)

Alexander GardnerJoseph T. Barbieri

light chain roletoxicologyenzymesphotomedicinetoxinologyneurosciencebiochemistrytoxinsphotobiologyplant toxinsoptical propertiespharmacologyphototropinlight regulationredox biology

Multiple Domains of Staphylococcal Superantigen-Like Protein 11 (Ssl11) Contribute to Neutrophil Inhibition. Biochemistry (2022)

Chen YangJoseph T. BarbieriNancy M. DahmsChen Chen

microbiologyimmune responsesimmunologybiochemistry

1
2
3
4
5
19
10 / page

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Similar Faculty Members

Patrick Brennan

Institution

Colorado State University

clinical microbiology

core cell wall

Timothy Gerald Palzkill

Institution

Baylor College of Medicine

molecular biology

drug resistance mechanisms

Victor J. Torres

Institution

New York University

vaccination

communicable disease

Nicholas J. Mantis

Institution

University at Albany, SUNY

microbial pathogenesis

pathogen

Robert K. Ernst

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University of Maryland, Baltimore

applied microbiology

clinical microbiology

Courtney Aldrich

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University of Minnesota

medicinal chemistry

pharmacology

Vern Schramm

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Albert Einstein College of Medicine

protein modeling

protein structure

Matthew Waldor

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pathogen characterization

clinical microbiology

Suzanne Walker

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molecular metabolism

drug resistance analysis

Eric Skaar

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emerging infectious disease

acinetobacter baumannii