Faculty

Institution

Unit

Venue

Cornelius Gati

Assistant Professor of Biological Sciences Chemistry Quantitative and Computational Biology and Pharmacology and Pharmaceutical Sciences

University of Southern California

Affiliations

Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences

Department of Pharmacology and Pharmaceutical Sciences

Natural Sciences

Biological Sciences

Quantitative and Computational Biology

College of Letters, Arts and Sciences

Natural Sciences

Cornelius Gati is currently serving as an Alfred E. Mann School Of Pharmacy And Pharmaceutical Sciences Assistant Professor of Biological Sciences Chemistry Quantitative and Computational Biology and Pharmacology and Pharmaceutical Sciences at University of Southern California.

Honors

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Experiences

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Education

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Cornelius Gati

University of Southern California

Assistant Professor of Biological Sciences Chemistry Quantitative and Computational Biology and Pharmacology and Pharmaceutical Sciences

You can click a keyword to filter the displayed items

structural biology molecular biology crystallography biophysics biochemistry protein structure pharmacology protein science receptors molecular pharmacology biomolecular structure x-ray free-electron laser membrane biology g protein-coupled receptor scientific communication structural molecular biology enzyme inhibition molecular physiology crystal structures x-ray diffraction x-ray crystallography receptor (biochemistry) structural basis proteomics scientific computing pharmacological research crystal research protein x-ray crystallography protein transport ambient temperature serial femtosecond crystallography serial crystallography chemical sciences quantum science molecular science molecular cell biology biological chemistry genome biology science education structure determination structure elucidation hormonal receptor inhibitory activity mechanisms of action membrane transport structural genomics structural bioinformatics rna biology nature behavioral ecology lipid science e-science mining science cellular structure macromolecular architecture nature conservation melatonin viral pathogenesis host response antiviral responses cellular immune responses innate immune system cardiovascular function induced pluripotent stem cells femtosecond x-ray laser rhodopsin bound angiotensin receptor heterodimeric mechanism canonical wnt metabotropic gaba receptor cryo-em structure subtype selectivity xfel structures concentric-flow electrokinetic injector photosystem ii poxviral hemagglutinin biomolecular engineering cryoelectron microscopy

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecular Basis of Human Gaba Transporter 3 Inhibition. Nature Communications (2025)

Ravi YadavGye Won HanCornelius Gati

molecular neurodegenerationprotein sciencemembrane transportcell signalingcell traffickingbiochemistryintracellular traffickingmolecular physiologymolecular cell biologyprotein transportmolecular biologytherapeutic targetsmolecular pharmacologysystems biologysignal transductiongene expressionenzyme inhibition

Peer Review Funding Agencies De La Recherche - French National Research Agency (Anr, Fr). (2024)

scientific communicationresearch policysocial sciencesresearch ethicsscientific integrityinternational researchpublic policyscientometrics

Structural Basis of Inverse Agonism via Inactive Kappa Opioid Receptor: G Protein Complexes.. (2024)

non-peptide ligandneuropeptide receptorsneuropharmacologyinverse agonismaddiction biologyg protein complexesbiochemistryreceptor (biochemistry)pharmacologyg protein-coupled receptormolecular pharmacologystructural basispharmacological researchreceptors

Molecular Basis of Anaphylatoxin Binding, Activation, and Signaling Bias at Complement Receptors. Cell (2023)

Manish K. YadavJagannath MaharanaRavi YadavShirsha SahaParishmita SarmaChahat SoniVinay SinghSayantan SahaManisankar GangulyXaria X. LiSamanwita MohapatraSudha MishraHtet A. KhantMohamed ChamiTrent M. WoodruffRamanuj BanerjeeArun K. ShuklaCornelius Gati

redox biologytherapeutic targetslate bindinganaphylatoxin bindingcell signalingmolecular biologyinhibitory activitybiochemistrycomplement receptorsmolecular immunologyinflammationprotein sciencereceptor (biochemistry)molecular physiologymolecular cell biologymolecular pharmacologysignal transductionenzyme inhibitionmolecular regulationbiomolecular engineering

Slc6A1 Variant Pathogenicity, Molecular Function, and Phenotype: A Genetic and Clinical Analysis. Brain (2023)

pathologyslc6a1 variant pathogenicitypathogenesisimmunologymolecular medicinevariant interpretationdisease gene identificationallelic variantclinical analysismolecular diagnosticsclinical proteomicshuman geneticsgenetic epidemiologymolecular functioninborn errors of immunity

Structure of the Thrombopoietin-Mpl Receptor Complex is a Blueprint for Biasing Hematopoiesis. Cell (2023)

Naotaka TsutsumiZahra MasoumiSophie C. JamesJulie A. TuckerHauke WinkelmannWilliam GreyLora K. PictonLucie MossSteven C. WilsonNathanael A. CaveneyKevin M. JudeCornelius GatiJacob PiehlerIan S. HitchcockK. Christopher Garcia

haematopoiesisimmunologycell biologyhematologythrombopoietin-mpl receptor complexmolecular biologythrombopoiesisreceptors

Structural Basis of Gaba Reuptake Inhibition. Nature (2022)

inhibitory activityneuropharmacologybiochemistryenzyme inhibitionpharmacologymolecular pharmacologystructural basispharmacological researchstructural molecular biologymechanisms of action

A Mycobacterial Abc Transporter Mediates the Uptake of Hydrophilic Compounds. Nature (2020)

S. RempelC. GatiM. NijlandC. ThangaratnarajahA. KaryolaimosJ. W. de GierA. GuskovD. J. Slotboom

bacteriaprotein transportvascular biologymicrobial physiologymolecular biologymembrane transporthydrobiologiacellular physiologybiochemistrymicrobiologydrug resistancemycobacterial abc transportersolvent extractionmicrobial pathogenesishydrobiologymolecular metabolismhydrophilic compoundsmolecular physiologymembrane biologyantibiotics

Exosomes From Induced Pluripotent Stem Cell–Derived Cardiomyocytes Promote Autophagy for Myocardial Repair. Journal of the American Heart Association (2020)

Michelle R. SantosoGentaro IkedaYuko TadaJi‐Hye JungEvgeniya VaskovaRaymond G. SierraCornelius GatiAndrew B. GoldstoneDaniel von BornstaedtPraveen ShuklaJoseph C. WuSoichi WakatsukiY. Joseph WooPhillip C. Yang

cardiovascular diseasecardiovascular functionstem cell researchstem cellsautophagypharmacologyinduced pluripotent stem cellsstem-cell therapycell biologycerebrovascular diseasegene expressionmyocardial repairbiological engineeringcardiologycellular therapycardiovascular researchregenerative medicinecell transplantationstem cell transplantation

High Resolution Cryoem Structure of the Ring-Shaped Virulence Factor Espb From Mycobacterium Tuberculosis. Journal of Structural Biology X (2020)

biological macromoleculesprotein x-ray crystallographytuberculosismycobacterium tuberculosisbiomolecular structurestructural genomicsmicrobiologybacteriastructural bioinformaticsmolecular biologyprotein structurestructural molecular biologystructural biology

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Cornelius Gati

Assistant Professor of Biological Sciences Chemistry Quantitative and Computational Biology and Pharmacology and Pharmaceutical Sciences

University of Southern California

Affiliations

Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences

Department of Pharmacology and Pharmaceutical Sciences

Natural Sciences

Biological Sciences

Quantitative and Computational Biology

College of Letters, Arts and Sciences

Natural Sciences

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Cornelius Gati

University of Southern California

Assistant Professor of Biological Sciences Chemistry Quantitative and Computational Biology and Pharmacology and Pharmaceutical Sciences

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Molecular Basis of Human Gaba Transporter 3 Inhibition. Nature Communications (2025)

Ravi YadavGye Won HanCornelius Gati

Peer Review Funding Agencies De La Recherche - French National Research Agency (Anr, Fr). (2024)

scientific communicationresearch policysocial sciencesresearch ethicsscientific integrityinternational researchpublic policyscientometrics

Structural Basis of Inverse Agonism via Inactive Kappa Opioid Receptor: G Protein Complexes.. (2024)

Molecular Basis of Anaphylatoxin Binding, Activation, and Signaling Bias at Complement Receptors. Cell (2023)

Slc6A1 Variant Pathogenicity, Molecular Function, and Phenotype: A Genetic and Clinical Analysis. Brain (2023)

Structure of the Thrombopoietin-Mpl Receptor Complex is a Blueprint for Biasing Hematopoiesis. Cell (2023)

haematopoiesisimmunologycell biologyhematologythrombopoietin-mpl receptor complexmolecular biologythrombopoiesisreceptors

Structural Basis of Gaba Reuptake Inhibition. Nature (2022)

inhibitory activityneuropharmacologybiochemistryenzyme inhibitionpharmacologymolecular pharmacologystructural basispharmacological researchstructural molecular biologymechanisms of action

A Mycobacterial Abc Transporter Mediates the Uptake of Hydrophilic Compounds. Nature (2020)

S. RempelC. GatiM. NijlandC. ThangaratnarajahA. KaryolaimosJ. W. de GierA. GuskovD. J. Slotboom

Exosomes From Induced Pluripotent Stem Cell–Derived Cardiomyocytes Promote Autophagy for Myocardial Repair. Journal of the American Heart Association (2020)

High Resolution Cryoem Structure of the Ring-Shaped Virulence Factor Espb From Mycobacterium Tuberculosis. Journal of Structural Biology X (2020)

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