Faculty

Institution

Unit

Venue

Charles Murtaugh

Associate Professor

University of Utah

Affiliations

Spencer Fox Eccles School of Medicine

Human Genetics

Charles Murtaugh is currently serving as a Human Genetics Associate Professor at University of Utah.

Honors

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Experiences

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Education

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Charles Murtaugh

University of Utah

Associate Professor

You can click a keyword to filter the displayed items

developmental biology genetics cell biology cancer biology tumor biology molecular biology cancer research pancreatic cancer oncology gene expression mammalian biology membrane biology signal transduction cell signaling developmental science medicinal research cell regulation cancer genomics hepatology stem cell research molecular physiology tissue development cell lineage cancer genetics vascular biology developmental cell protein science oncogenes signaling pathways organ development transcription regulation gene regulation cell transplantation liver physiology cell metabolism renal function human sciences cancer growth developmental genetics molecular regulation pancreas development exocrine pancreas lineage tracing genome biology molecular cell biology cellular biochemistry leukemia secretory pathway disease progression path dependence specific resistance functional modification optimal development embryonic development metabolic regulation dermal structure cutaneous biology adrenal disease renal pathophysiology host-guest chemistry genetic determinants developmental endocrinology intrinsic impurity genomic analyses molecular subtypes pancreatic differentiation controls multiple steps intraepithelial neoplasia intestinal fate direct regulation beta-cell development pancreatic acinar adult pancreas dynamic contribution tumor initiation mitochondrial pyruvate carrier microbiome pathology microbiology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract B114: Mutational"Lineage Traces" of an Acinar Cell-Of-Origin in Human Pancreatic Ductal Adenocarcinoma. Cancer Research (2024)

Charles Murtaugh

lineage tracescancer researchpancreatic canceracinar cell-of-originmolecular biology

Key Transcriptional Effectors of the Pancreatic Acinar Phenotype and Oncogenic Transformation. PLoS ONE (2023)

Ana Azevedo-PoulyMichael A. HaleGalvin H. SwiftChinh Q. HoangTye G. DeeringJumin XueThomas M. WilkieL. Charles MurtaughRaymond J. MacDonald

molecular regulationgene functionhuman geneticsbiochemistryoncogenic transformationpancreatic acinar phenotypemolecular cancerplo biologyprotein scienceepigenomicsfunctional genomicsmolecular physiologytumor biologygene expressiontranscription regulationgeneticsmolecular biologyoncogeneskey transcriptional effectorsepigeneticsgene regulation

Matters Arising: Insufficient Evidence That Pancreatic β Cells Are Derived From Adult Ductal Neurog3-Expressing Progenitors. Cell stem cell (2023)

Judith MagenheimMiguel Angel MaestroNadav SharonPedro L. HerreraL. Charles MurtaughJanel KoppMaike SanderGuoqiang GuDouglas A. MeltonJorge FerrerYuval Dor

gene expressionstem cell researchregenerative medicineneurogeneticsgeneticsdevelopmental geneticsinsufficient evidencestem cellsdevelopmental biologyneuroscience

Befa, a Microbiota-Secreted Membrane Disrupter, Disseminates to the Pancreas and Increases β Cell Mass. Cell Metabolism (2022)

Jennifer Hampton HillMichelle Sconce MassaquoiEmily Goers SweeneyElena S. WallPhilip JahlRickesha BellKaren KallioDaniel DerrickL. Charles MurtaughRaghuveer ParthasarathyS. James RemingtonJune L. RoundKaren Guillemin

microbiomegut microbesdermatologypathogen transmissionpharmacologyhost responseapplied microbiologyclinical microbiologyveterinary medicinesecondary metabolismmicrobiota-secreted membrane disrupterrespiratory medicinemembrane biologymetabolismmicrobiologycell metabolism

Using in Vitro Experiments to Determine Mfn2’S Function in Als (P1-13.008). Neurology (2022)

Kristi RussellJonathan DownieSummer GibsonKarla FigueroaMark BrombergCharles MurtaughLynn JordeStefan Pulst

neurologygene expressionvitro experimentsgeneticsneuroscienceamyotrophic lateral sclerosis

Mfn2 Influences Amyotrophic Lateral Sclerosis Pathology. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Kristi L. RussellJonathan M. DownieSummer B. GibsonKarla P. FigueroaCody J. SteelyMark B. BrombergL. Charles MurtaughLynn B. JordeStefan M. Pulst

neurologyneuropathologypathologyneuroscienceamyotrophic lateral sclerosis

Pathogenic Effect of Tp73 Gene Variants in People With Amyotrophic Lateral Sclerosis. Neurology (2021)

Kristi L. RussellJonathan M. DownieSummer B. GibsonSpyridoula TsetsouMatthew D. KeefeJerry A. DuranKarla P. FigueroaMark B. BrombergL. Charles MurtaughJoshua L. BonkowskyStefan M. PulstLynn B. Jorde

neurologypathogenic effectpathogenesisgeneticspathologyamyotrophic lateral sclerosis

A Pivotal Role of Androgen Signaling in Notch-Responsive Cells in Prostate Development, Maturation, and Regeneration. Differentiation (2019)

Joseph AldahlEun-Jeong YuYongfeng HeErika HookerMonica WongVien LeAdam OlsonDong-Hoon LeeWon Kyung KimCharles L. MurtaughGerald R. CunhaZijie Sun

neurologynotch-responsive cellscell signalingprostate developmentdevelopmental biologyprostate cancerneuroscience

Prevention and Reversion of Pancreatic Tumorigenesis Through a Differentiation-Based Mechanism. Developmental Cell (2019)

Nathan M. KrahShuba M. NarayananDeanne E. YugawaJulie A. StraleyChristopher V.E. WrightRaymond J. MacDonaldL. Charles Murtaugh

treatment and preventionpancreatic tumorigenesiscancer biologydevelopmental celltissue developmentgeneticsdifferentiation-based mechanismdevelopmental biologydevelopmental sciencecellular differentiationtumor biologycell biology

Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. Cell Metabolism (2019)

Claire L. BensardDona R. WisidagamaKristofor A. OlsonJordan A. BergNathan M. KrahJohn C. SchellSara M. NowinskiSarah FogartyAlex J. BottPeng WeiKatja K. DoveJason M. TannerVanja PanicAhmad CluntunSandra LettlovaChristian S. EarlDavid F. NamnathKarina Vázquez-ArreguínClaudio J. VillanuevaDean TantinL. Charles MurtaughKimberley J. EvasonGregory S. DuckerCarl S. ThummelJared Rutter

physiologycell regulationcancer biologycancer researchmetabolic regulationtumor initiationmolecular regulationmitochondrial pyruvate carriermolecular biologycell metabolismtumor biologygene regulationcell biology

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Charles Murtaugh

Associate Professor

University of Utah

Affiliations

Spencer Fox Eccles School of Medicine

Human Genetics

Charles Murtaugh is currently serving as a Human Genetics Associate Professor at University of Utah.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Charles Murtaugh

University of Utah

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract B114: Mutational"Lineage Traces" of an Acinar Cell-Of-Origin in Human Pancreatic Ductal Adenocarcinoma. Cancer Research (2024)

Charles Murtaugh

lineage tracescancer researchpancreatic canceracinar cell-of-originmolecular biology

Key Transcriptional Effectors of the Pancreatic Acinar Phenotype and Oncogenic Transformation. PLoS ONE (2023)

Ana Azevedo-PoulyMichael A. HaleGalvin H. SwiftChinh Q. HoangTye G. DeeringJumin XueThomas M. WilkieL. Charles MurtaughRaymond J. MacDonald

Matters Arising: Insufficient Evidence That Pancreatic β Cells Are Derived From Adult Ductal Neurog3-Expressing Progenitors. Cell stem cell (2023)

Judith MagenheimMiguel Angel MaestroNadav SharonPedro L. HerreraL. Charles MurtaughJanel KoppMaike SanderGuoqiang GuDouglas A. MeltonJorge FerrerYuval Dor

gene expressionstem cell researchregenerative medicineneurogeneticsgeneticsdevelopmental geneticsinsufficient evidencestem cellsdevelopmental biologyneuroscience

Befa, a Microbiota-Secreted Membrane Disrupter, Disseminates to the Pancreas and Increases β Cell Mass. Cell Metabolism (2022)

Using in Vitro Experiments to Determine Mfn2’S Function in Als (P1-13.008). Neurology (2022)

Kristi RussellJonathan DownieSummer GibsonKarla FigueroaMark BrombergCharles MurtaughLynn JordeStefan Pulst

neurologygene expressionvitro experimentsgeneticsneuroscienceamyotrophic lateral sclerosis

Mfn2 Influences Amyotrophic Lateral Sclerosis Pathology. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Kristi L. RussellJonathan M. DownieSummer B. GibsonKarla P. FigueroaCody J. SteelyMark B. BrombergL. Charles MurtaughLynn B. JordeStefan M. Pulst

neurologyneuropathologypathologyneuroscienceamyotrophic lateral sclerosis

Pathogenic Effect of Tp73 Gene Variants in People With Amyotrophic Lateral Sclerosis. Neurology (2021)

Kristi L. RussellJonathan M. DownieSummer B. GibsonSpyridoula TsetsouMatthew D. KeefeJerry A. DuranKarla P. FigueroaMark B. BrombergL. Charles MurtaughJoshua L. BonkowskyStefan M. PulstLynn B. Jorde

neurologypathogenic effectpathogenesisgeneticspathologyamyotrophic lateral sclerosis

A Pivotal Role of Androgen Signaling in Notch-Responsive Cells in Prostate Development, Maturation, and Regeneration. Differentiation (2019)

Joseph AldahlEun-Jeong YuYongfeng HeErika HookerMonica WongVien LeAdam OlsonDong-Hoon LeeWon Kyung KimCharles L. MurtaughGerald R. CunhaZijie Sun

neurologynotch-responsive cellscell signalingprostate developmentdevelopmental biologyprostate cancerneuroscience

Prevention and Reversion of Pancreatic Tumorigenesis Through a Differentiation-Based Mechanism. Developmental Cell (2019)

Nathan M. KrahShuba M. NarayananDeanne E. YugawaJulie A. StraleyChristopher V.E. WrightRaymond J. MacDonaldL. Charles Murtaugh

Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier. Cell Metabolism (2019)

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