Faculty

Institution

Unit

Venue

Scott W. Hiebert

Professor of Biochemistry Hortense B Ingram Chair in Cancer Research

Vanderbilt University

Affiliations

School of Medicine

Department of Biochemistry

Scott W. Hiebert is currently serving as a Biochemistry Professor of Biochemistry Hortense B Ingram Chair in Cancer Research at Vanderbilt University.

Honors

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Experiences

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Education

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Scott W. Hiebert

Vanderbilt University

Professor of Biochemistry Hortense B Ingram Chair in Cancer Research

You can click a keyword to filter the displayed items

molecular biology genetics cell biology gene expression tumor biology oncology hematology cancer biology immunology molecular cell biology oncogenes protein science transcription regulation cell signaling cancer genetics transcription factors medicinal research leukemia molecular and cellular biology molecular cancer gene regulation cell regulation transcription (biology) cellular biology gene function genome biology molecular regulation hematological malignancies protein expression enzyme inhibition cellular biochemistry molecular physiology cancer treatment cancer cells tumor suppressors myeloid neoplasia mammalian biology cellular physiology cancer genomics fusion protein acute myeloid leukemia cell death anti-cancer agents structural molecular biology cytogenetics acute leukemia bone research signaling pathways molecular virology rna biology myelopoiesis tumor targeting viral genetics lymphoid neoplasia cell cycle biomolecular interactions apoptosis chromosome biology nuclear matrix transcriptional repression heme signaling epigenomics osteoblast differentiation transcriptional regulation developmental genetics malignant blood disorders gene characterization fusion proteins histone deacetylases multiple chromosomal translocations rb protein retinoblastoma gene product genome stability chromatin structure nucleotide sequence nuclear export oncogenic agent systems biology chromatin nascent transcription oncogenic transcription factors

Notable Scholarly Works

Notable Federal Grants

Collaborators

ENRSA: A Faster and More Powerful Approach for Nascent Transcriptome Analysis. GigaScience (2025)

gene expression profilingbiomedical informaticspowerful approachbioinformaticsnucleic acidssequence analysisgenomicsgenome biologymolecular informaticsmolecular cell biologytranscription (biology)molecular biologynascent transcriptome analysistranscriptomics technologygene expressiontranscriptomegenetics

Mtg16 Nhr1 Mutations Cause Defects in Lymphopoiesis and the Response to Anemia. Experimental Hematology (2025)

pathologymutagenesis (molecular biology technique)haematopoiesisaplastic anemiacell biologyhematologybone marrow transplantationimmune responsesleukemiainborn errors of immunity

Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Abdulkadir ElmasHillary M. LaydenJacob D. EllisLuke N. BartlettXian ZhaoReika Kawabata-IwakawaHideru ObinataScott W. HiebertKuan-lin Huang

precision medicinegenomicsfunctional genomicsmolecular biologygene expressionmedical geneticspersonalized medicinegenetics

Histone Deacetylases Maintain Expression of the Pluripotent Gene Network via Recruitment of Rna Polymerase II to Coding and Noncoding Loci. Genome Research (2024)

Richard D.W. KellyKristy R. StengelAditya ChandruLyndsey C. JohnsonScott W. HiebertShaun M. Cowley

rna polymerase iigenomicspluripotent gene networknoncoding locimolecular biologygeneticsgene expressiongenome biology

Mtgr1 is Required to Maintain Small Intestinal Stem Cell Populations. Cell Death and Differentiation (2024)

Sarah P ShortRachel E BrownZhengyi ChenJennifer M PilatBailey A McElligottLeslie M MeenderinkAlexander C BickartKoral M BluntJustin JacobseJing WangAlan J SimmonsYanwen XuYilin YangBobak ParangYash A ChoksiJeremy A GoettelKen S LauScott W HiebertChristopher S Williams

regenerative medicinetumor biologycell deathimmunologystem cellshematologydermatologymolecular biology

Mutant Foxo1 Controls an Oncogenic Network via Enhancer Accessibility. Cell Genomics (2024)

Hillary M. LaydenJacob D. EllisMonica L. BomberLuke N. BartlettScott W. HiebertKristy R. Stengel

oncogenic networktumor biologymutagenesis (molecular biology technique)mutagenesiscell biologygene regulationenhancer accessibilitymolecular biologygene expressioncancer geneticscancer genomicsgenetics

Abstract 6274: Preclinical Characterization of the Bet Inhibitor, Incb057643, in Combination With Ruxolitinib for Treatment of Myeloproliferative Neoplasms (Mpn). Cancer Research (2023)

Michelle PuseyGaurang TrivediBob CollinsNina ZolotarjovaPat FeldmanMonica BomberJacob EllisKristy StengelCynthia TimmersHamza CelikMatt StubbsJeff JacksonScott HiebertSusan WeeSunkyu Kim

radiation oncologyanti-cancer agentspreclinical characterizationbet inhibitorcancer researchpharmacologymyeloproliferative neoplasmscancer treatmentcancer careoncologycancer biology

A Dual Indexed Approach to Small Rna Sequencing Library Preparation for Pro-Seq. Research Square (Research Square) (2023)

Hillary M. LaydenAngela L. JonesJacob D. EllisScott W. Hiebert

bioinformatics databasegenomicsmolecular biologytranscriptomics technologyresearch libraryrna biologybioinformatics

Chemical-Genetics Refines Transcription Factor Regulatory Circuits. Trends in cancer (2023)

Hillary M. LaydenAnna E. JohnsonScott W. Hiebert

tumor biologycancer biologytranscription factorsepigeneticsgene regulationcancer researchtranscription regulationmolecular biologymedicinemolecular regulationcancer genomicsoncologygenetics

Data From Bet Inhibition Enhances the Antileukemic Activity of Low-Dose Venetoclax in Acute Myeloid Leukemia. (2023)

Haley E. RamseyDalton GreenwoodSusu ZhangMerrida ChildressMaria P. ArrateAgnieszka E. GorskaLonda FullerYue ZhaoKristy StengelMelissa A. FischerMatthew C. StubbsPhillip C.C. LiuKelli BoydJeffrey C. RathmellScott W. HiebertMichael R. Savona

oncogenescell linesradiation oncologyimmunologybet inhibitionhematological malignancieshematologycancer researchacute myeloid leukemiapharmacologytherapeutic targetsleukemiaoncologymyeloid neoplasia

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Scott W. Hiebert

Professor of Biochemistry Hortense B Ingram Chair in Cancer Research

Vanderbilt University

Affiliations

School of Medicine

Department of Biochemistry

Scott W. Hiebert is currently serving as a Biochemistry Professor of Biochemistry Hortense B Ingram Chair in Cancer Research at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Scott W. Hiebert

Vanderbilt University

Professor of Biochemistry Hortense B Ingram Chair in Cancer Research

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

ENRSA: A Faster and More Powerful Approach for Nascent Transcriptome Analysis. GigaScience (2025)

Mtg16 Nhr1 Mutations Cause Defects in Lymphopoiesis and the Response to Anemia. Experimental Hematology (2025)

pathologymutagenesis (molecular biology technique)haematopoiesisaplastic anemiacell biologyhematologybone marrow transplantationimmune responsesleukemiainborn errors of immunity

Expression-Driven Genetic Dependency Reveals Targets for Precision Medicine. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Abdulkadir ElmasHillary M. LaydenJacob D. EllisLuke N. BartlettXian ZhaoReika Kawabata-IwakawaHideru ObinataScott W. HiebertKuan-lin Huang

precision medicinegenomicsfunctional genomicsmolecular biologygene expressionmedical geneticspersonalized medicinegenetics

Histone Deacetylases Maintain Expression of the Pluripotent Gene Network via Recruitment of Rna Polymerase II to Coding and Noncoding Loci. Genome Research (2024)

Richard D.W. KellyKristy R. StengelAditya ChandruLyndsey C. JohnsonScott W. HiebertShaun M. Cowley

rna polymerase iigenomicspluripotent gene networknoncoding locimolecular biologygeneticsgene expressiongenome biology

Mtgr1 is Required to Maintain Small Intestinal Stem Cell Populations. Cell Death and Differentiation (2024)

regenerative medicinetumor biologycell deathimmunologystem cellshematologydermatologymolecular biology

Mutant Foxo1 Controls an Oncogenic Network via Enhancer Accessibility. Cell Genomics (2024)

Hillary M. LaydenJacob D. EllisMonica L. BomberLuke N. BartlettScott W. HiebertKristy R. Stengel

Abstract 6274: Preclinical Characterization of the Bet Inhibitor, Incb057643, in Combination With Ruxolitinib for Treatment of Myeloproliferative Neoplasms (Mpn). Cancer Research (2023)

Michelle PuseyGaurang TrivediBob CollinsNina ZolotarjovaPat FeldmanMonica BomberJacob EllisKristy StengelCynthia TimmersHamza CelikMatt StubbsJeff JacksonScott HiebertSusan WeeSunkyu Kim

radiation oncologyanti-cancer agentspreclinical characterizationbet inhibitorcancer researchpharmacologymyeloproliferative neoplasmscancer treatmentcancer careoncologycancer biology

A Dual Indexed Approach to Small Rna Sequencing Library Preparation for Pro-Seq. Research Square (Research Square) (2023)

Hillary M. LaydenAngela L. JonesJacob D. EllisScott W. Hiebert

bioinformatics databasegenomicsmolecular biologytranscriptomics technologyresearch libraryrna biologybioinformatics

Chemical-Genetics Refines Transcription Factor Regulatory Circuits. Trends in cancer (2023)

Hillary M. LaydenAnna E. JohnsonScott W. Hiebert

tumor biologycancer biologytranscription factorsepigeneticsgene regulationcancer researchtranscription regulationmolecular biologymedicinemolecular regulationcancer genomicsoncologygenetics

Data From Bet Inhibition Enhances the Antileukemic Activity of Low-Dose Venetoclax in Acute Myeloid Leukemia. (2023)

oncogenescell linesradiation oncologyimmunologybet inhibitionhematological malignancieshematologycancer researchacute myeloid leukemiapharmacologytherapeutic targetsleukemiaoncologymyeloid neoplasia

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10 / page

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University of Miami

molecular biology

haematopoiesis

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Institution

University of California, Los Angeles

imaging genomics

cell biology

Harold L. Moses

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oncogene

molecular cancer

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proteomics

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oncology

pathology

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Institution

University of Pennsylvania

free radical biology

biological microenvironments

Robert J. Coffey, M.D

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gi neoplasia

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Zhongming Zhao

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single-cell omics

personalized medicine

Amato J. Giaccia

Institution

Stanford University

radiation oncology

cancer biology

Aristotelis Tsirigos

Institution

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hi-c data analysis

health informatics