Faculty

Institution

Unit

Venue

Christopher V. Wright

Professor

Vanderbilt University

Affiliations

Graduate School

Cell and Developmental Biology

School of Medicine

Department of Cell and Developmental Biology

Christopher V. Wright is currently serving as a Cell And Developmental Biology Professor at Vanderbilt University.

Honors

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Experiences

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Education

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Christopher V. Wright

Vanderbilt University

Professor

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developmental biology genetics gene expression cell biology molecular biology membrane biology developmental science embryonic development endocrinology hepatology mammalian biology gene function avian biology developmental genetics transcription regulation signal transduction cell regulation developmental neurobiology tumor biology transcription factors molecular cell biology liver physiology molecular physiology genome biology protein science cancer biology vascular biology stem cell research cellular physiology medicinal research cancer genetics redox biology cellular biology molecular regulation digestive diseases gene regulation cellular biochemistry insulin signaling fish biology developmental endocrinology tissue development organ development protein expression signaling pathways endocrine research renal function gastrointestinal oncology clinical gastroenterology pancreatic cancer gene regulatory networks molecular neurobiology cellular neurobiology host factors cell physiology rna biology gametogenesis pancreatic ductal adenocarcinoma left-right asymmetry brain function metabolic regulation clinical medicine cancer genomics pancreatic progenitors mouse embryos pancreas organogenesis pancreatic b-cell function pancreatic tumorigenesis persistent expression insulin gene transcription supraphysiologic glucose concentration xenopus embryos homeobox genes asymmetric expression vertebrate embryo pancreatic outgrowth rostral duodenum developmental cell epigenetics pancreas development cell specialization developmental system morphogenesis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Epithelial Outgrowth Through Mesenchymal Rings Drives Alveologenesis. JCI Insight (2025)

Nicholas M. NegrettiYeongseo SonPhilip CrookeErin J. PlosaJohn T. BenjaminChristopher S. JetterClaire BunnNicholas MignemiJohn MariniAlice N. HackettMeaghan RansomShriya GargDavid NicholsSusan H. GuttentagHeather H. PuaTimothy S. BlackwellWilliam ZachariasDavid B. FrankJohn A. KozubAnita Mahadevan-JansenEvan KrystofiakJonathan A. KropskiChristopher V.E. WrightBryan MillisJennifer M.S. Sucre

developmental biologyepithelial outgrowthdermatologycell biologyregenerative medicineangiogenesismembrane biologyvascular biology

Positive Autoregulation of Sox17 is Necessary for Gallbladder and Extrahepatic Biliary Duct Formation. Development (2025)

Linh T. TrinhRyan R. FinnelAnna B. OsipovichJessica R. MusselmanLeesa L. SampsonChristopher V.E. WrightMark A. Magnuson

cell biologyautophagyautoimmunitybiliary disordermetastasisurologyliver transplantationliver physiologypositive autoregulationhepatologyallostatic loadhost factorsimmunologyvascular biologynephrologymolecular gastroenterologybiliary tracteus-guided gallbladder drainageinflammation

Bronchopulmonary Dysplasia With Pulmonary Hypertension Associates With Loss of Semaphorin Signaling and Functional Decrease in Foxf1 Expression. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Shawyon P. ShiraziNicholas M. NegrettiChristopher S. JetterAlexandria L. SharkeyShriya GargMeghan E. KappDevan WilkinsGabrielle FortierSaahithi MallapragadaNicholas E. BanovichChristopher V. E. WrightDavid B. FrankJonathan A. KropskiJennifer M. S. Sucre

pulmonary hypertension associatesgene expressionfunctional decreasebronchopulmonary dysplasiasemaphorin signalingrespiratory medicinemolecular biologypulmonary diseases

Mapping Histological and Functional Maturation of Human Endocrine Pancreas Across Early Postnatal Periods. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Diane C. SaundersNathaniel HartFong Cheng PanConrad V. ReihsmannAlexander L. HopkirkNike IzmaylovShaojun MeiBrandon A. SherrodCorey DavisJeff DuryeaRachana HaliyurRadhika AramandlaHeather DuraiGreg PoffenbergerAlexandra MartinAmanda L. PosgaiIrina KusmartsevaMaria L. BeeryMingder YangHakmook KangDale L. GreinerLeonard D. ShultzJean-Philippe CartaillerKristie I. AamodtRita BottinoMark A. AtkinsonChristopher V.E. WrightAlvin C. PowersMarcela Brissova

developmental biologyearly postnatal periodsendocrinologyfunctional maturationhuman endocrine pancreas

Telocyte Recruitment During the Emergence of a Metaplastic Niche in the Stomach. Cellular and Molecular Gastroenterology and Hepatology (2024)

Yoojin SohnBlake Flores SemyonovHilana El-MekkoussiChristopher V E WrightKlaus H KaestnerEunyoung ChoiJames R Goldenring

developmental biologygastroenterologyveterinary medicinecell biologytelocyte recruitmenthealth sciencesmetaplastic niche

Single-Cell Rna Sequencing of Sox17- Expressing Lineages Reveals Distinct Gene Regulatory Networks and Dynamic Developmental Trajectories. Stem Cells (2023)

Linh T TrinhAnna B OsipovichBryan LiuShristi ShresthaJean-Philippe CartaillerChristopher V E WrightMark A Magnuson

developmental biologystem cell researchgeneticsgene expressioncell lineagedevelopmental geneticsgenomicsrna biologydynamic developmental trajectoriesgenome biologymolecular biologysingle-cell rna sequencing

Crispr Screening Uncovers a Central Requirement for Hhex in Pancreatic Lineage Commitment and Plasticity Restriction. Nature Cell Biology (2022)

Dapeng YangHyunwoo ChoZakieh TayyebiAbhijit ShuklaRenhe LuoGary DixonValeria UrsuStephanie StranskyDaniel M. TremmelSara D. SackettRichard KocheSamuel J. KaplanQing V. LiJiwoon ParkZengrong ZhuBess P. RosenJulian PulecioZhong-Dong ShiYaron BramRobert E. SchwartzJon S. OdoricoSimone SidoliChristopher V. WrightChristina S. LeslieDanwei Huangfu

epigeneticsgeneticspancreatic lineage commitmenthuman biologycellular biologycrisprcell biologygenomicsmembrane biologyplasticity restrictiongenome biologymolecular biology

MO1136: Recruitment of Foxl1+ Telocytes During Metaplasia Development in the Stomach. Gastroenterology (2022)

Yoojin SohnBlake Flores SemyonovChristopher V. WrightKlaus H. KaestnerEunyoung ChoiJames R. Goldenring

developmental biologygastroenterologycancer biologymetaplasia developmentcell biologyimmunologyvenereology

Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development. Gastro Hep Advances (2022)

Angelica S. Martinez-RamirezThomas L. BordersLeena PaulMatthew SchipmaXinkun WangFarida KorobovaChristopher V. WrightBeatriz Sosa-Pineda

developmental biologyhepatologyspecific temporal requirementgastroenterologyveterinary medicinecell biologyrespiratory medicinehealth sciences

Retraction Note: Transient Cytokine Treatment Induces Acinar Cell Reprogramming and Regenerates Functional Beta Cell Mass in Diabetic Mice. Nature Biotechnology (2020)

Luc BaeyensMarie LemperGunter LeuckxSofie De GroefPaola BonfantiGeert StangéRuth ShemerChristoffer NordDavid W. ScheelFong C. PanUlf AhlgrenGuoqiang GuDoris A. StoffersYuval DorJorge FerrerGerard GradwohlChristopher V. E. WrightMark Van de CasteeleMichael S. GermanLuc BouwensHarry Heimberg

diabetesfragmentation effectdiabetic miceneurosciencepharmacologymammalian biologystem cell researchcell physiologyanimal biotechnologymembrane biologycellular immune responsesadaptive immune systemimmunologybiotechnologycytokinesmedicinal researchcell reprogrammingregeneration (biology)retraction noteregenerative medicinecellular physiology

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Christopher V. Wright

Professor

Vanderbilt University

Affiliations

Graduate School

Cell and Developmental Biology

School of Medicine

Department of Cell and Developmental Biology

Christopher V. Wright is currently serving as a Cell And Developmental Biology Professor at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Christopher V. Wright

Vanderbilt University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Epithelial Outgrowth Through Mesenchymal Rings Drives Alveologenesis. JCI Insight (2025)

developmental biologyepithelial outgrowthdermatologycell biologyregenerative medicineangiogenesismembrane biologyvascular biology

Positive Autoregulation of Sox17 is Necessary for Gallbladder and Extrahepatic Biliary Duct Formation. Development (2025)

Linh T. TrinhRyan R. FinnelAnna B. OsipovichJessica R. MusselmanLeesa L. SampsonChristopher V.E. WrightMark A. Magnuson

Bronchopulmonary Dysplasia With Pulmonary Hypertension Associates With Loss of Semaphorin Signaling and Functional Decrease in Foxf1 Expression. bioRxiv (Cold Spring Harbor Laboratory) (2024)

pulmonary hypertension associatesgene expressionfunctional decreasebronchopulmonary dysplasiasemaphorin signalingrespiratory medicinemolecular biologypulmonary diseases

Mapping Histological and Functional Maturation of Human Endocrine Pancreas Across Early Postnatal Periods. bioRxiv (Cold Spring Harbor Laboratory) (2024)

developmental biologyearly postnatal periodsendocrinologyfunctional maturationhuman endocrine pancreas

Telocyte Recruitment During the Emergence of a Metaplastic Niche in the Stomach. Cellular and Molecular Gastroenterology and Hepatology (2024)

Yoojin SohnBlake Flores SemyonovHilana El-MekkoussiChristopher V E WrightKlaus H KaestnerEunyoung ChoiJames R Goldenring

developmental biologygastroenterologyveterinary medicinecell biologytelocyte recruitmenthealth sciencesmetaplastic niche

Single-Cell Rna Sequencing of Sox17- Expressing Lineages Reveals Distinct Gene Regulatory Networks and Dynamic Developmental Trajectories. Stem Cells (2023)

Linh T TrinhAnna B OsipovichBryan LiuShristi ShresthaJean-Philippe CartaillerChristopher V E WrightMark A Magnuson

Crispr Screening Uncovers a Central Requirement for Hhex in Pancreatic Lineage Commitment and Plasticity Restriction. Nature Cell Biology (2022)

epigeneticsgeneticspancreatic lineage commitmenthuman biologycellular biologycrisprcell biologygenomicsmembrane biologyplasticity restrictiongenome biologymolecular biology

MO1136: Recruitment of Foxl1+ Telocytes During Metaplasia Development in the Stomach. Gastroenterology (2022)

Yoojin SohnBlake Flores SemyonovChristopher V. WrightKlaus H. KaestnerEunyoung ChoiJames R. Goldenring

developmental biologygastroenterologycancer biologymetaplasia developmentcell biologyimmunologyvenereology

Specific Temporal Requirement of Prox1 Activity During Pancreatic Acinar Cell Development. Gastro Hep Advances (2022)

Angelica S. Martinez-RamirezThomas L. BordersLeena PaulMatthew SchipmaXinkun WangFarida KorobovaChristopher V. WrightBeatriz Sosa-Pineda

developmental biologyhepatologyspecific temporal requirementgastroenterologyveterinary medicinecell biologyrespiratory medicinehealth sciences

Retraction Note: Transient Cytokine Treatment Induces Acinar Cell Reprogramming and Regenerates Functional Beta Cell Mass in Diabetic Mice. Nature Biotechnology (2020)

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infectious diseases

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University of California, San Diego

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