Faculty

Institution

Unit

Venue

Colin Burns

Professor

East Carolina University

Affiliations

Thomas Harriot College of Arts and Sciences

Chemistry

Colin Burns is currently serving as a Chemistry Professor at East Carolina University.

Honors

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Experiences

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Education

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Colin Burns

East Carolina University

Professor

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pharmacology structural biology protein science anti-cancer agents biochemistry protein structure oncology immunology biophysics medicinal research tumor targeting prion protein inorganic chemistry cancer research coordination chemistry protein chemistry biological inorganic chemistry cancer treatment transition metal chemistry structural molecular biology pharmacotherapy metalloproteins therapeutic efficacy immune responses hiv virology redox biology molecular structure molecular cancer enzyme inhibition molecular basis skin cancer cancer biology drug development copper binding infection control medical virology general virology metals biomolecules biomolecular structure host response virulence factors virus-host interactions viral pathogenesis antiviral therapy lead identification coordination complex molecular substrates structural composition protein mass spectrometry novel therapies cancer prevention apoptosis protein purification experimental analysis structure elucidation melanoma oncogenic agent inorganic materials peptide therapeutics pharmaceutical chemistry octarepeat domain copper binding sites molecular features n-terminal domain cd spectroscopy recombinant prion protein copper coordination infected mice manganese transporter mnth critical virulence determinant multiple isomers low copper esi-ms analysis peptide-zinc complexes medicinal chemistry organic chemistry biophysical chemistry biomolecular engineering molecular recognition

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ Sup 12,14 /Sup -Prostamide J Sub 2 /Sub, as a Selective Antitumor Therapeutic. (2023)

Daniel A. LadinEman SolimanRene EscobedoTimothy L. FitzgeraldLi V. YangColin BurnsRukiyah Van Dross

anti-cancer agentstherapeutic efficacyselective antitumoroncologydrug developmentmedicinal chemistrymedicinal researchpeptide therapeuticspharmacologytherapeutic targetstumor targetingenzyme inhibitiondrug discoverynovel prostamidedrug delivery

Supplementary Figure 1 From Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ Sup 12,14 /Sup -Prostamide J Sub 2 /Sub, as a Selective Antitumor Therapeutic. (2023)

Daniel A. LadinEman SolimanRene EscobedoTimothy L. FitzgeraldLi V. YangColin BurnsRukiyah Van Dross

cancer immunotherapyselective antitumorpharmacologyfunctional modificationtherapeutic targetspeptide scienceurologytumor biologymedicinal chemistryfuture medicinal chemistrybrain tumor researchnovel prostamidetherapeutic efficacyanti-cancer agentsmolecular cancertumor targetingmedicinal researchpharmaceutical chemistrybiomolecular engineeringprostate cancer

Damage-Associated Molecular Pattern (Damp) Activation in Melanoma: Investigation of the Immunogenic Activity of 15-Deoxy, Δ12,14 Prostamide J2. Oncotarget (2020)

Ahmed ElhassannyRene EscobedoDaniel LadinColin BurnsRukiyah Van Dross

cancer immunotherapytumor biologyanti-cancer agentsoncologydermatologyoncogenic agentimmunologypharmacologytherapeutic targetstumor targetingdna repairmelanomaskin cancerdamage-associated molecular patternimmunogenic activitymedicinal research

Prostaglandin D2-Ethanolamide Induces Skin Cancer Apoptosis by Suppressing the Activity of Cellular Antioxidants. Prostaglandins & Other Lipid Mediators (2019)

Ahmed E.M. ElhassannyDaniel A. LadinEman SolimanHussam AlbassamAndrew MorrisRobert KobetKathleen ThayneColin BurnsAllison S. DanellRukiyah Van Dross

tumor biologycancer immunotherapyanti-cancer agentsclinical lipidologyskin cancerinflammationoncologycancer researchapoptosisdermatologypharmacologycancer treatmentcancer preventionenzyme inhibitionhealth sciencescellular antioxidantsmedicinal researchpharmacotherapy

Zn2+-Binding in the Glutamate-Rich Region of the Intrinsically Disordered Protein Prothymosin-Alpha. JBIC Journal of Biological Inorganic Chemistry (2018)

Sriramya GarapatiWilliam MonteithChris WilsonAnastasiia KostenkoJohn M. KenneyAllison S. DanellColin S. Burns

inorganic chemistryglutamate-rich regionprotein sciencebiological inorganic chemistryneuroscienceprotein structurestructural molecular biologybiochemistryprotein chemistrymolecular biologystructural biologystructural chemistry

Abstract 2193: Structural Modification of the Chemotherapeutic Anandamide: Designing Anti-Cancer Agents and Investigating Their Cox-2 Metabolic Products. Cancer Research (2017)

Andrew MorrisEman SolimanRukiyah Van DrossColin Burns

anti-cancer agentsmedicinedesignoncologycancer researchcancer biologymedicinal chemistrydrug developmentstructural modificationpharmacologycancer treatmentchemotherapeutic anandamideclinical researchpharmacotherapy

Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide J2, as a Selective Antitumor Therapeutic. Molecular Cancer Therapeutics (2017)

Daniel A. LadinEman SolimanRene EscobedoTimothy L. FitzgeraldLi V. YangColin BurnsRukiyah Van Dross

anti-cancer agentsselective antitumormedicinecancer researchoncologymolecular cancernovel therapiesmedicinal chemistrynovel prostamidepharmacologycancer treatmentprostate cancertumor targetingdrug discoverypharmacotherapytherapeutic efficacy

Abstract 3809: Synthesis of the Novel Prostamide, 15-Deoxy-Δ12,14 Prostaglandin J2-Ethanolamide, and Characterization of Its Anti-Tumor Activity. Cancer Research (2015)

Daniel LadinColin BurnsRukiyah T. Van Dross

anti-cancer agentscancer researchoncologycancer biologymedicinal chemistrycancer carepharmacologycancer treatmentanti-tumor activityprostate cancertumor targetingdrug discoverynovel prostamide

Calorimetric Investigation of Copper Binding in the N-Terminal Region of the Prion Protein at Low Copper Loading: Evidence for an Entropically Favorable First Binding Event. Inorganic Chemistry (2014)

Devi Praneetha GogineniAnne M. SpuchesColin S. Burns

inorganic chemistrycell biologyprotein scienceneuroscienceprotein structurepharmacologyprion proteinmetalloproteinsproteomicsbiological inorganic chemistryredox biologyinorganic materialslow copper loadingstructural biologycopper bindingcalorimetric investigationn-terminal regionstructural molecular biologyprotein chemistrycoordination chemistrytransition metal chemistry

Field- and Temperature-Dependent 13 C Nmr Studies of the Edta–Zn 2+ Complex: Insight Into Structure and Dynamics via Relaxation Measurements. The Journal of Physical Chemistry B (2014)

Sriramya GarapatiColin S. BurnsA. A. Rodriguez

biophysicsrelaxation measurementsnmr studiesmolecular structurenuclear magnetic resonanceexperimental analysiscondensed matter physicsmaterials sciencephysical chemistrystructure elucidationphysicscoordination chemistrystructural biology

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Colin Burns

Professor

East Carolina University

Affiliations

Thomas Harriot College of Arts and Sciences

Chemistry

Colin Burns is currently serving as a Chemistry Professor at East Carolina University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Colin Burns

East Carolina University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ Sup 12,14 /Sup -Prostamide J Sub 2 /Sub, as a Selective Antitumor Therapeutic. (2023)

Daniel A. LadinEman SolimanRene EscobedoTimothy L. FitzgeraldLi V. YangColin BurnsRukiyah Van Dross

Supplementary Figure 1 From Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ Sup 12,14 /Sup -Prostamide J Sub 2 /Sub, as a Selective Antitumor Therapeutic. (2023)

Daniel A. LadinEman SolimanRene EscobedoTimothy L. FitzgeraldLi V. YangColin BurnsRukiyah Van Dross

Damage-Associated Molecular Pattern (Damp) Activation in Melanoma: Investigation of the Immunogenic Activity of 15-Deoxy, Δ12,14 Prostamide J2. Oncotarget (2020)

Ahmed ElhassannyRene EscobedoDaniel LadinColin BurnsRukiyah Van Dross

Prostaglandin D2-Ethanolamide Induces Skin Cancer Apoptosis by Suppressing the Activity of Cellular Antioxidants. Prostaglandins & Other Lipid Mediators (2019)

Ahmed E.M. ElhassannyDaniel A. LadinEman SolimanHussam AlbassamAndrew MorrisRobert KobetKathleen ThayneColin BurnsAllison S. DanellRukiyah Van Dross

Zn2+-Binding in the Glutamate-Rich Region of the Intrinsically Disordered Protein Prothymosin-Alpha. JBIC Journal of Biological Inorganic Chemistry (2018)

Sriramya GarapatiWilliam MonteithChris WilsonAnastasiia KostenkoJohn M. KenneyAllison S. DanellColin S. Burns

Abstract 2193: Structural Modification of the Chemotherapeutic Anandamide: Designing Anti-Cancer Agents and Investigating Their Cox-2 Metabolic Products. Cancer Research (2017)

Andrew MorrisEman SolimanRukiyah Van DrossColin Burns

Synthesis and Evaluation of the Novel Prostamide, 15-Deoxy, Δ12,14-Prostamide J2, as a Selective Antitumor Therapeutic. Molecular Cancer Therapeutics (2017)

Daniel A. LadinEman SolimanRene EscobedoTimothy L. FitzgeraldLi V. YangColin BurnsRukiyah Van Dross

Abstract 3809: Synthesis of the Novel Prostamide, 15-Deoxy-Δ12,14 Prostaglandin J2-Ethanolamide, and Characterization of Its Anti-Tumor Activity. Cancer Research (2015)

Daniel LadinColin BurnsRukiyah T. Van Dross

anti-cancer agentscancer researchoncologycancer biologymedicinal chemistrycancer carepharmacologycancer treatmentanti-tumor activityprostate cancertumor targetingdrug discoverynovel prostamide

Devi Praneetha GogineniAnne M. SpuchesColin S. Burns

Field- and Temperature-Dependent 13 C Nmr Studies of the Edta–Zn 2+ Complex: Insight Into Structure and Dynamics via Relaxation Measurements. The Journal of Physical Chemistry B (2014)

Sriramya GarapatiColin S. BurnsA. A. Rodriguez

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