Faculty

Institution

Unit

Venue

Brian Stockman

Professor

Adelphi University

Affiliations

Chemistry

College of Arts and Sciences

Brian Stockman is currently serving as a Chemistry Professor at Adelphi University.

Honors

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Experiences

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Education

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Brian Stockman

Adelphi University

Professor

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biochemistry molecular biology microbiology nuclear magnetic resonance enzymes protein nmr enzyme inhibition protein structure structural biology structural molecular biology protein science medicinal chemistry biomolecular structure nuclear magnetic resonance spectroscopy nucleoside ribohydrolase biophysics protein folding bioorganic chemistry molecular structure peptide science clinical microbiology biological chemistry protein chemistry protein assembly pharmaceutical chemistry enzyme specificity ribohydrolase inhibitors biophysical chemistry magnetic resonance biological macromolecules medicinal research digital scholarship distance education infection control nuclear quadrupole resonance nucleic acid chemistry pharmaceutical research cellular enzymology protein function protein modeling rational drug design virtual classroom online education instructional video student engagement classroom instruction structure elucidation parasitic protozoa direct observation diagnostic microbiology pathogen detection pathogen characterization functional selectivity inhibitory activity flavin mononucleotide oxidized states proton-pump inhibitor drugs trichomonas vaginalis druggable antitrichomonal target biophysical chemistry laboratory four-helix bundle protein ligand-efficient inhibitors ligand-efficient scaffolds fragment screening web-based videoconferencing student-led engagement structure-guided insight parasitic nucleoside hydrolase nmr spectroscopy deep learning algorithms nucleoside hydrolase molecular informatics biomolecular structure prediction biomolecular analysis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1596: Translation of Nucleoside Ribohydrolase Enzyme Assays for Purified Enzymes to Direct Measurement of Enzyme Activity in Trichomonas Vaginalis Cells Using 19F and 13C-Edited 1H Nmr Spectroscopy. Journal of Biological Chemistry (2023)

Brian StockmanCarlos VenturaValerie DeykinaNickolas Khayan LontscharitschEdina SaljaninAri GilMadison CanestrariMaham Mahmood

purified enzymesenzyme activityenzymestrichomonas vaginalis cellsnmr spectroscopybiochemistrybiological chemistry

A Riboside Hydrolase That Salvages Both Nucleobases and Nicotinamide in the Auxotrophic Parasite Trichomonas Vaginalis. Journal of Biological Chemistry (2023)

Marco PatroneGregory S. GalasynFiona KerinMattias M. NyitrayDavid W. ParkinBrian J. StockmanMassimo Degano

enzyme specificityparasitic protozoaparasitologybiochemistrymicrobiologyauxotrophic parasite trichomonasmolecular biologybiological chemistryriboside hydrolasemicrobial pathogenesis

Direct Measurement of Nucleoside Ribohydrolase Enzyme Activities in Trichomonas Vaginalis Cells Using 19 F and 13 C-Edited 1 H Nmr Spectroscopy. Analytical Chemistry (2023)

Brian J. StockmanCarlos A. VenturaValerie S. DeykinaNickolas Khayan LontscharitschEdina SaljaninAri GilMadison CanestrariMaham Mahmood

enzymesdirect observationdirect measurementspectroscopybiochemistrymicrobiologyprotein nmrmolecular biologynuclear magnetic resonancestructural biology

Parasitology Assays to Assess Trichomonas Vaginalis Nucleoside Ribohydrolase Inhibitors. The FASEB Journal (2022)

Maria ChimariosCarlos VenturaBrian J. Stockman

pathogen detectionclinical microbiologyinfectious diseasespathogen characterizationpathogenic bacteriaribohydrolase inhibitorsparasitology assaysparasitologyantimicrobial resistancemicrobiologydiagnostic microbiologypathogenspharmacologyenzyme inhibitioninfection controlmicrobial pathogenesis

Structure‐Activity Relationships for Several Series of Fragment‐Based Inhibitors That Target Trichomonas Vaginalis Nucleoside Ribohydrolase Enzymes. The FASEB Journal (2022)

Edina SaljaninErum AjmalDavi VanegasMelissa VanAlstine‐ParrisBrian Stockman

several seriesenzymesprotein sciencestructure-activity relationshipsfunctional selectivityfragment-based inhibitorsribohydrolase enzymesbiochemistrymicrobiologymolecular biologytherapeutic targetsprotein structuredrug discoveryenzyme inhibitionstructural biology

Structure-Guided Insight Into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase. Biochemistry (2022)

Samantha N. MuellersMattias M. NyitrayNicholas ReynarowychEdina SaljaninAnnie Laurie BenzieAlan R. SchoenfeldBrian J. StockmanKaren N. Allen

enzyme specificitystructure-guided insightenzymesprotein sciencebiochemistryparasitic nucleoside hydrolasestructure elucidationmolecular biologypharmacologyprotein structurestructural molecular biologystructural biology

Discovery of Ligand-Efficient Scaffolds for the Design of Novel Trichomonas Vaginalis Uridine Nucleoside Ribohydrolase Inhibitors Using Fragment Screening. ACS Omega (2019)

Shannon AulettaWagma CaravanJulia K. PersaudSamantha F. ThuilotDean G. BrownDavid W. ParkinBrian J. Stockman

ribohydrolase inhibitorssynthetic biologybiochemistryrational drug designmolecular biologydrug discoveryenzyme inhibitionligand-efficient scaffoldsfragment screening

Ligand-Efficient Inhibitors of Trichomonas Vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase. ACS Infectious Diseases (2019)

Samantha N. MuellersJuliana A. GonzalezAbinash KaurVital SapojnikovAnnie Laurie BenzieDean G. BrownDavid W. ParkinBrian J. Stockman

ligand-efficient inhibitorsinfectious diseasesnucleoside ribohydrolasemicrobiologypathogenspharmacologyenzyme inhibition

Nmr-Based Activity Assays for Determining Compound Inhibition, Ic Sub 50 /Sub Values, Artifactual Activity, and Whole-Cell Activity of Nucleoside Ribohydrolases. Journal of Visualized Experiments (2019)

Brian J. StockmanAbinash KaurJulia K. PersaudMaham MahmoodSamantha F. ThuilotMelissa B. EmilcarMadison CanestrariJuliana A. GonzalezShannon AulettaVital SapojnikovWagma CaravanSamantha N. Muellers

compound inhibitionwhole-cell activitybiochemistrynuclear magnetic resonance spectroscopynmr-based activity assaysartifactual activitynuclear magnetic resonancenucleoside ribohydrolases

Structure‐Activity Relationships of Fragment‐Based Inhibitors of Trichomonas Vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase. The FASEB Journal (2019)

Melissa EmilcarAngelica LeonardoTian LiZaafir DullooNafeesathul Hanan KabirAri GilMelissa A. VanAlstine‐ParrisBrian J. Stockman

structural molecular biologyenzymesinhibitory activityprotein sciencestructure-activity relationshipsnucleoside ribohydrolasefragment-based inhibitorsbiochemistrymicrobiologymolecular biologyprotein structureenzyme inhibition

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Brian Stockman

Professor

Adelphi University

Affiliations

Chemistry

College of Arts and Sciences

Brian Stockman is currently serving as a Chemistry Professor at Adelphi University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Brian Stockman

Adelphi University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Brian StockmanCarlos VenturaValerie DeykinaNickolas Khayan LontscharitschEdina SaljaninAri GilMadison CanestrariMaham Mahmood

purified enzymesenzyme activityenzymestrichomonas vaginalis cellsnmr spectroscopybiochemistrybiological chemistry

A Riboside Hydrolase That Salvages Both Nucleobases and Nicotinamide in the Auxotrophic Parasite Trichomonas Vaginalis. Journal of Biological Chemistry (2023)

Marco PatroneGregory S. GalasynFiona KerinMattias M. NyitrayDavid W. ParkinBrian J. StockmanMassimo Degano

enzyme specificityparasitic protozoaparasitologybiochemistrymicrobiologyauxotrophic parasite trichomonasmolecular biologybiological chemistryriboside hydrolasemicrobial pathogenesis

Direct Measurement of Nucleoside Ribohydrolase Enzyme Activities in Trichomonas Vaginalis Cells Using 19 F and 13 C-Edited 1 H Nmr Spectroscopy. Analytical Chemistry (2023)

Brian J. StockmanCarlos A. VenturaValerie S. DeykinaNickolas Khayan LontscharitschEdina SaljaninAri GilMadison CanestrariMaham Mahmood

enzymesdirect observationdirect measurementspectroscopybiochemistrymicrobiologyprotein nmrmolecular biologynuclear magnetic resonancestructural biology

Parasitology Assays to Assess Trichomonas Vaginalis Nucleoside Ribohydrolase Inhibitors. The FASEB Journal (2022)

Maria ChimariosCarlos VenturaBrian J. Stockman

Structure‐Activity Relationships for Several Series of Fragment‐Based Inhibitors That Target Trichomonas Vaginalis Nucleoside Ribohydrolase Enzymes. The FASEB Journal (2022)

Edina SaljaninErum AjmalDavi VanegasMelissa VanAlstine‐ParrisBrian Stockman

Structure-Guided Insight Into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase. Biochemistry (2022)

Samantha N. MuellersMattias M. NyitrayNicholas ReynarowychEdina SaljaninAnnie Laurie BenzieAlan R. SchoenfeldBrian J. StockmanKaren N. Allen

Discovery of Ligand-Efficient Scaffolds for the Design of Novel Trichomonas Vaginalis Uridine Nucleoside Ribohydrolase Inhibitors Using Fragment Screening. ACS Omega (2019)

Shannon AulettaWagma CaravanJulia K. PersaudSamantha F. ThuilotDean G. BrownDavid W. ParkinBrian J. Stockman

ribohydrolase inhibitorssynthetic biologybiochemistryrational drug designmolecular biologydrug discoveryenzyme inhibitionligand-efficient scaffoldsfragment screening

Ligand-Efficient Inhibitors of Trichomonas Vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase. ACS Infectious Diseases (2019)

Samantha N. MuellersJuliana A. GonzalezAbinash KaurVital SapojnikovAnnie Laurie BenzieDean G. BrownDavid W. ParkinBrian J. Stockman

ligand-efficient inhibitorsinfectious diseasesnucleoside ribohydrolasemicrobiologypathogenspharmacologyenzyme inhibition

Brian J. StockmanAbinash KaurJulia K. PersaudMaham MahmoodSamantha F. ThuilotMelissa B. EmilcarMadison CanestrariJuliana A. GonzalezShannon AulettaVital SapojnikovWagma CaravanSamantha N. Muellers

compound inhibitionwhole-cell activitybiochemistrynuclear magnetic resonance spectroscopynmr-based activity assaysartifactual activitynuclear magnetic resonancenucleoside ribohydrolases

Structure‐Activity Relationships of Fragment‐Based Inhibitors of Trichomonas Vaginalis Adenosine/Guanosine Preferring Nucleoside Ribohydrolase. The FASEB Journal (2019)

Melissa EmilcarAngelica LeonardoTian LiZaafir DullooNafeesathul Hanan KabirAri GilMelissa A. VanAlstine‐ParrisBrian J. Stockman

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