Faculty

Institution

Unit

Venue

Ashis Basu

Professor

University of Connecticut

Affiliations

College of Liberal Arts and Sciences

Chemistry

Ashis Basu is currently serving as a Chemistry Professor at University of Connecticut.

Honors

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Experiences

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Education

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Ashis Basu

University of Connecticut

Professor

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molecular biology genetics biochemistry mutagenesis dna repair mutagenesis (molecular biology technique) toxicology pharmacology structural biology nucleic acids enzymes protein science cancer genetics molecular genetics gene expression replication biological chemistry cancer biology genome biology molecular cancer oligonucleotides biochemical sciences clinical chemistry epigenetic changes cancer genomics enzyme inhibition mammalian biology structural molecular biology enzyme catalysis redox biology dna analysis microbial genetics radiation chemistry radiation biology nucleic acid chemistry dna damage translesion synthesis escherichia coli molecular cell biology molecular structure oncogenes gene editing molecular substrates rna biology molecular research biocatalysis mammalian cells uvrabc nuclease dna duplex dna polymerases y-family dna polymerase molecular science chemical sciences protein chemistry experimental toxicology radiation effects radiation exposure structure determination clinical toxicology nucleic acid amplification biological inorganic chemistry cross-link oncogenic agent carbon-based materials microbial toxins molecular catalysis cancer risk thymine glycol site-specific mutagenesis human endonuclease iii nmr studies error-free bypass abasic site mutagenic potential error-prone translesion synthesis chromosome biology medicinal chemistry genome instability

Notable Scholarly Works

Notable Federal Grants

Collaborators

5-Formylcytosine Mediated Dna-Peptide Cross-Link Induces Predominantly Semi-Targeted Mutations in Both Escherichia Coli and Human Cells. Journal of Biological Chemistry (2024)

Jan Henric T. BacurioPriscilla YawsonJenna ThomfordeQi ZhangHonnaiah Vijay KumarHolly Den HartogNatalia Y. TretyakovaAshis K. Basu

gene therapygene expressioncancer geneticssemi-targeted mutationsbiochemical geneticsgeneticsmolecular and cellular biologycancer genomicsmolecular geneticsmolecular biologybiological chemistrymedicinal researchescherichia colicell biology

8-Oxodguo and Fapy•Dg Mutagenicity in Escherichia Coli Increases Significantly When They Are Part of a Tandem Lesion With 5-Formyl-2′-Deoxyuridine. Chemical Research in Toxicology (2024)

Srijana DasguptaShijun GaoHaozhe YangMarc M. GreenbergAshis K. Basu

tandem lesionclinical microbiologymutagenesisgeneticstoxicologychemistrybacteriamutagenesis (molecular biology technique)microbiology

Mutagenesis and Repair of γ-Radiation- and Radical-Induced Tandem Dna Lesions. DNA (2024)

Ashis K. BasuLaureen C. ColisJan Henric T. Bacurio

radiation oncologymutagenesisradiation biologygeneticsdna repairradiationmutagenesis (molecular biology technique)

8-Oxo-2′-Deoxyguanosine Replication in Mutational Hot Spot Sequences of the P53 Gene in Human Cells is Less Mutagenic Than That of the Corresponding Formamidopyrimidine. Chemical Research in Toxicology (2023)

Stephen StanioJan Henric T. BacurioHaozhe YangMarc M. GreenbergAshis K. Basu

cancer geneticsreplicationmolecular cancermutagenesisgeneticscancer genomicsmolecular biologytoxicologyoncogenestumor biologycell biology

From Mutation and Repair to Therapeutics. DNA (2023)

Ashis BasuDeyu Li

genomicsmedicinepharmacologycell therapymutagenesisgeneticspharmacotherapybiological therapiescellular therapydrug discoverycancer treatmentdna repairmutagenesis (molecular biology technique)molecular medicine

Synergistic Effects on Mutagenicity of Tandem Lesions Containing 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine or Fapy•Dg Flanked by a 3′ 5-Formyl-2′-Deoxyuridine in Human Cells. DNA repair (2023)

Jan Henric T. BacurioShijun GaoHaozhe YangAshis K. BasuMarc M. Greenberg

genome biologygene therapygene expressioncancer geneticsgene editinggenome editingsynergistic effectscancer researchmutagenesisgeneticstandem lesionsmolecular biologymutagenesis (molecular biology technique)cell biology

Establishing Linkages Among Dna Damage, Mutagenesis, and Genetic Diseases. Chemical Research in Toxicology (2022)

Ashis K. BasuJohn M. Essigmann

dna damagegeneticstoxicologydna repairgenetic diseasespathologymutagenesis

Structural Dynamics of a Common Mutagenic Oxidative Dna Lesion in Duplex Dna and During Dna Replication. Journal of the American Chemical Society (2022)

Benjamin J. RyanHaozhe YangJan Henric T. BacurioMallory R. SmithAshis K. BasuMarc M. GreenbergBret D. Freudenthal

biophysicsstructural biologygeneticsmolecular biologyduplex dnadna replicationmutagenesis

Sequence Context Effects of Replication of Fapy•Dg in Three Mutational Hot Spot Sequences of the P53 Gene in Human Cells. DNA repair (2021)

Jan Henric T. BacurioHaozhe YangSpandana NaldigaBrent V. PowellBenjamin J. RyanBret D. FreudenthalMarc M. GreenbergAshis K. Basu

genomicsgenome biologysequence context effectscancer geneticsreplicationcancer researchmolecular cancergeneticscancer genomicsmolecular virologymolecular biologyoncogenesdna repaircancer biologytumor biologycell biology

6-Nitrochrysene-Derived C8-2′-Deoxyadenosine Adduct: Synthesis of Site-Specific Oligodeoxynucleotides and Mutagenicity in Escherichia Coli. Chemical Research in Toxicology (2020)

Brent V. PowellAshis K. Basu

nucleic acid chemistryclinical chemistrymutagenesisorganic synthesischemical biologysite-specific oligodeoxynucleotidesmolecular biologytoxicologychemistrybiological chemistryoligonucleotidesmutagenesis (molecular biology technique)chemical synthesisbiochemistry

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Ashis Basu

Professor

University of Connecticut

Affiliations

College of Liberal Arts and Sciences

Chemistry

Ashis Basu is currently serving as a Chemistry Professor at University of Connecticut.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ashis Basu

University of Connecticut

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

5-Formylcytosine Mediated Dna-Peptide Cross-Link Induces Predominantly Semi-Targeted Mutations in Both Escherichia Coli and Human Cells. Journal of Biological Chemistry (2024)

Jan Henric T. BacurioPriscilla YawsonJenna ThomfordeQi ZhangHonnaiah Vijay KumarHolly Den HartogNatalia Y. TretyakovaAshis K. Basu

8-Oxodguo and Fapy•Dg Mutagenicity in Escherichia Coli Increases Significantly When They Are Part of a Tandem Lesion With 5-Formyl-2′-Deoxyuridine. Chemical Research in Toxicology (2024)

Srijana DasguptaShijun GaoHaozhe YangMarc M. GreenbergAshis K. Basu

tandem lesionclinical microbiologymutagenesisgeneticstoxicologychemistrybacteriamutagenesis (molecular biology technique)microbiology

Mutagenesis and Repair of γ-Radiation- and Radical-Induced Tandem Dna Lesions. DNA (2024)

Ashis K. BasuLaureen C. ColisJan Henric T. Bacurio

radiation oncologymutagenesisradiation biologygeneticsdna repairradiationmutagenesis (molecular biology technique)

Stephen StanioJan Henric T. BacurioHaozhe YangMarc M. GreenbergAshis K. Basu

cancer geneticsreplicationmolecular cancermutagenesisgeneticscancer genomicsmolecular biologytoxicologyoncogenestumor biologycell biology

From Mutation and Repair to Therapeutics. DNA (2023)

Ashis BasuDeyu Li

Synergistic Effects on Mutagenicity of Tandem Lesions Containing 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine or Fapy•Dg Flanked by a 3′ 5-Formyl-2′-Deoxyuridine in Human Cells. DNA repair (2023)

Jan Henric T. BacurioShijun GaoHaozhe YangAshis K. BasuMarc M. Greenberg

Establishing Linkages Among Dna Damage, Mutagenesis, and Genetic Diseases. Chemical Research in Toxicology (2022)

Ashis K. BasuJohn M. Essigmann

dna damagegeneticstoxicologydna repairgenetic diseasespathologymutagenesis

Structural Dynamics of a Common Mutagenic Oxidative Dna Lesion in Duplex Dna and During Dna Replication. Journal of the American Chemical Society (2022)

Benjamin J. RyanHaozhe YangJan Henric T. BacurioMallory R. SmithAshis K. BasuMarc M. GreenbergBret D. Freudenthal

biophysicsstructural biologygeneticsmolecular biologyduplex dnadna replicationmutagenesis

Sequence Context Effects of Replication of Fapy•Dg in Three Mutational Hot Spot Sequences of the P53 Gene in Human Cells. DNA repair (2021)

Jan Henric T. BacurioHaozhe YangSpandana NaldigaBrent V. PowellBenjamin J. RyanBret D. FreudenthalMarc M. GreenbergAshis K. Basu

6-Nitrochrysene-Derived C8-2′-Deoxyadenosine Adduct: Synthesis of Site-Specific Oligodeoxynucleotides and Mutagenicity in Escherichia Coli. Chemical Research in Toxicology (2020)

Brent V. PowellAshis K. Basu

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Institution

Stony Brook University

natural product communication

medicinal chemistry

John-Stephen Taylor

Institution

Washington University in St. Louis

breast cancer imaging

heat shock proteins

Carmelo Rizzo

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Vanderbilt University

molecular biology

mutagenesis

Michael P. Stone

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molecular biology

biochemistry

George W. Teebor MD

Institution

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molecular biology

dna repair

Paul L. Modrich

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molecular biology

genetics

Charles E. McKenna

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future medicinal chemistry

medicinal chemistry

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University of Chicago

molecular biology

genetics

Gregory Verdine

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therapeutic modalities

peptide

Laurence Hurley

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oncogene

cancer biology