Faculty

Institution

Unit

Venue

Anna Mapp

Edwin Vedejs Collegiate Professor of Chemistry and Research Professor Life Sciences Institute

University of Michigan

Affiliations

College of Literature, Science, and The Arts

Department of Chemistry

Anna Mapp is currently serving as a College Of Literature, Science, And The Arts Edwin Vedejs Collegiate Professor of Chemistry and Research Professor Life Sciences Institute at University of Michigan.

Honors

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Experiences

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Education

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Anna Mapp

University of Michigan

Edwin Vedejs Collegiate Professor of Chemistry and Research Professor Life Sciences Institute

You can click a keyword to filter the displayed items

biochemistry molecular biology chemical biology biomolecular engineering protein science transcription regulation pharmacology transcription (biology) medicinal chemistry gene expression structural biology biological chemistry enzymes chemical sciences transcription factors small molecules enzyme inhibition transition metal chemistry peptide science gene regulation medicinal research molecular regulation molecular science peptides combinatorial chemistry protein chemistry protein expression molecular physiology structural molecular biology coordination chemistry biomolecular interactions peptide synthesis protein-protein interactions biochemical sciences molecular cell biology pharmaceutical chemistry cancer biology stereoselective synthesis cell regulation synthetic chemistry appetite control protein synthesis gene function rational drug design protein biosynthesis biochemical interaction artificial transcriptional activators redox biology oncogenes chemical biotechnology energy homeostasis protein modeling protein function high-throughput screening functional modification novel therapies drug targeting cancer treatment protein misfolding functional selectivity gastrointestinal peptide hormone neuropeptides key coactivator gaba release food intake b-amino acids chiral isoxazolines succinct synthesis modular design artificial transcription factors fine-tuning multiprotein complexes minimal motif covalent inhibition direct measurements pancreatic islet b-cells oscillatory glycolysis

Notable Scholarly Works

Notable Federal Grants

Collaborators

Uncovering Dynamic Protein Binding Events Using a Colorimetric Dye. SSRN Electronic Journal (2026)

biophysicsproteome researchbiomolecular interactionsprotein scienceprotein chemistryprotein foldingsingle-molecule detectionmolecular biologybiophysical chemistry

Abstract 1237 Development of a Rational Ligand Discovery Method for Dynamic Proteins. Journal of Biological Chemistry (2025)

rational drug designprotein scienceprotein designmolecular dockingbiological chemistrybiochemistrymolecular biology

Abstract 2341 Learning From Nature: Strategies for Drugging Dynamic Nuclear Proteins. Journal of Biological Chemistry (2024)

Anna Mapp

nuclear organizationprotein sciencedynamic nuclear proteinsbiological chemistrybiologybiochemistrymolecular biologydrug discovery

A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein–Protein Interactions. Angewandte Chemie International Edition (2024)

Olivia N. PattelliEstefanía Martínez ValdiviaMatthew S. BeyersdorfClint S. ReganMónica RivasKatherine A. HebertSofia D. MerajverTomasz CierpickiAnna K. Mapp

transcriptional activationtranscription (biology)protein-protein interactionsbiochemistryprotein expression

An Improved Synthesis of Compound 11, a Unique Bicyclic Melanocortin‐3 Antagonist. Peptide Science (2024)

Stephen T. JoyNaima S. DahirRoger D. ConeAnna K. Mapp

receptorsexperimental synthesischemical synthesisbioactive compoundsmedicinal chemistrydermatologymedicinal researchpeptide synthesispeptide scienceimmunologypeptide therapeuticsimproved synthesistherapeutic targetsmolecular biologytransition metal chemistrypeptides

Subthreshold Activation of the Melanocortin System Causes Generalized Sensitization to Anorectic Agents in Mice. Journal of Clinical Investigation (2024)

Naima S. DahirYijun GuiYanan WuPatrick R. SweeneyAlix A.J. RouaultSavannah Y. WilliamsLuis E. GimenezTomi K. SawyerStephen T. JoyAnna K. MappRoger D. Cone

receptorsgaba releasegastrointestinal peptide hormoneneuropharmacologyendocrinologypharmacological researchappetite controlenergy homeostasisfood intakeneuropsychopharmacologyneuroscienceneuropeptidespharmacologypsychoneuroendocrinologyphysiologyhypothalamic peptidenervous systemmolecular physiology

A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts Med25 Ppis. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Olivia N. PattelliEstefanía Martínez ValdiviaMatthew S. BeyersdorfClint S. ReganMónica RivasSofia D. MerajverTomasz CierpickiAnna K. Mapp

geneticsgene expressionmolecular neurosciencecell biologymolecular biology

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

biophysicschemistrycrystal diffraction studycrystal engineeringcrystal researchcrystallographycrystal structuresccdc 2157502structure elucidationstructure determinationchemical structuredeposited datasetstructural chemistry

C–H Radiocyanation of Bioactive Molecules via Sequential Iodination/Copper-Mediated Cross-Coupling. Chemical Science (2023)

Mami HorikawaStephen T. JoyLiam S. SharninghausenXia ShaoAnna K. MappPeter J. H. ScottMelanie S. Sanford

biomolecular engineeringbioactive compoundsc-h radiocyanationbioactive moleculeschemical sciencesbiochemistrycross-coupling reactiontransition metal chemistry

Garcinolic Acid Distinguishes Between Gackix Domains and Modulates Interaction Networks. ChemBioChem (2023)

Meghan E. BreenStephen T. JoyOmari J. BarutiMatthew S. BeyersdorfMadeleine J. HenleySamantha N. De SallePeter D. YcasAyza CroskeyTomasz CierpickiWilliam C. K. PomerantzAnna K. Mapp

medicinal chemistrybiochemistrypharmacologygackix domains

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Anna Mapp

Edwin Vedejs Collegiate Professor of Chemistry and Research Professor Life Sciences Institute

University of Michigan

Affiliations

College of Literature, Science, and The Arts

Department of Chemistry

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Anna Mapp

University of Michigan

Edwin Vedejs Collegiate Professor of Chemistry and Research Professor Life Sciences Institute

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Uncovering Dynamic Protein Binding Events Using a Colorimetric Dye. SSRN Electronic Journal (2026)

biophysicsproteome researchbiomolecular interactionsprotein scienceprotein chemistryprotein foldingsingle-molecule detectionmolecular biologybiophysical chemistry

Abstract 1237 Development of a Rational Ligand Discovery Method for Dynamic Proteins. Journal of Biological Chemistry (2025)

rational drug designprotein scienceprotein designmolecular dockingbiological chemistrybiochemistrymolecular biology

Abstract 2341 Learning From Nature: Strategies for Drugging Dynamic Nuclear Proteins. Journal of Biological Chemistry (2024)

Anna Mapp

nuclear organizationprotein sciencedynamic nuclear proteinsbiological chemistrybiologybiochemistrymolecular biologydrug discovery

A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts the Coactivator Med25 Protein–Protein Interactions. Angewandte Chemie International Edition (2024)

Olivia N. PattelliEstefanía Martínez ValdiviaMatthew S. BeyersdorfClint S. ReganMónica RivasKatherine A. HebertSofia D. MerajverTomasz CierpickiAnna K. Mapp

transcriptional activationtranscription (biology)protein-protein interactionsbiochemistryprotein expression

An Improved Synthesis of Compound 11, a Unique Bicyclic Melanocortin‐3 Antagonist. Peptide Science (2024)

Stephen T. JoyNaima S. DahirRoger D. ConeAnna K. Mapp

Subthreshold Activation of the Melanocortin System Causes Generalized Sensitization to Anorectic Agents in Mice. Journal of Clinical Investigation (2024)

Naima S. DahirYijun GuiYanan WuPatrick R. SweeneyAlix A.J. RouaultSavannah Y. WilliamsLuis E. GimenezTomi K. SawyerStephen T. JoyAnna K. MappRoger D. Cone

A Lipopeptidomimetic of Transcriptional Activation Domains Selectively Disrupts Med25 Ppis. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Olivia N. PattelliEstefanía Martínez ValdiviaMatthew S. BeyersdorfClint S. ReganMónica RivasSofia D. MerajverTomasz CierpickiAnna K. Mapp

geneticsgene expressionmolecular neurosciencecell biologymolecular biology

Ccdc 2157502: Experimental Crystal Structure Determination. The Cambridge Structural Database (2023)

Rao, YuPalumbo, Chad T.Venkatesh, AmritKeener, MeganStevanato, GabrieleChauvin, Anne-SophieMenzildjian, GeorgesKuzin, SergeiYulikov, MaximJeschke, GunnarLesage, AnneMazzanti, MarinellaEmsley, Lyndon

C–H Radiocyanation of Bioactive Molecules via Sequential Iodination/Copper-Mediated Cross-Coupling. Chemical Science (2023)

Mami HorikawaStephen T. JoyLiam S. SharninghausenXia ShaoAnna K. MappPeter J. H. ScottMelanie S. Sanford

biomolecular engineeringbioactive compoundsc-h radiocyanationbioactive moleculeschemical sciencesbiochemistrycross-coupling reactiontransition metal chemistry

Garcinolic Acid Distinguishes Between Gackix Domains and Modulates Interaction Networks. ChemBioChem (2023)

Meghan E. BreenStephen T. JoyOmari J. BarutiMatthew S. BeyersdorfMadeleine J. HenleySamantha N. De SallePeter D. YcasAyza CroskeyTomasz CierpickiWilliam C. K. PomerantzAnna K. Mapp

medicinal chemistrybiochemistrypharmacologygackix domains

1
2
3
4
5
12
10 / page

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