Faculty

Institution

Unit

Venue

H. Andy Zhong

Ralph Wardle Diamond Professor Interim Department Chair

University of Nebraska at Omaha

Affiliations

College of Arts and Sciences

Chemistry

H. Andy Zhong is currently serving as a Chemistry Ralph Wardle Diamond Professor Interim Department Chair at University of Nebraska At Omaha.

Honors

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Experiences

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Education

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H. Andy Zhong

University of Nebraska at Omaha

Ralph Wardle Diamond Professor Interim Department Chair

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pharmacology medicinal chemistry drug discovery medicine enzyme inhibition medicinal research molecular biology pharmacotherapy drug targeting pharmaceutical chemistry pharmaceutical sciences drug delivery oncology protein science rational drug design cancer treatment biological evaluation materials science enzymes clinical chemistry pharmaceutical research cancer research organic synthesis molecular modelling molecular docking anti-cancer agents drug development protein chemistry cellular therapy cancer care drug targets signaling pathways tumor targeting protein modeling selectivity studies virus research pharmaceutics controlled release material chemistry molecular cancer antiviral drug development isoform-specific inhibition updated review inhibitor design free energy calculations matrix metalloproteinase inhibitors cellular biochemistry chemical sciences antiviral research general virology inhibitory activity cataracts oxysterol molecular virology viral structural protein virus structure release mechanism therapeutic patent novel therapies pancreatic cancer experimental synthesis derivative (chemistry) polymer synthesis organic electronics x-ray crystallography biophysical modeling pharmaceutical technology protein tyrosine kinases inactive states top prescribed drugs lens clarity small-molecule inhibitors drug design anticancer drug target arthritis pain binding mode computational chemistry future medicinal chemistry protein design organic chemistry molecular informatics molecular design biochemistry biomolecular engineering bioorganic chemistry protein-ligand interactions

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cannabidiol Promotes Intestinal Cholesterol Uptake Mediated by Pregnane X Receptor. Frontiers in Endocrinology (2024)

Conner BrownWangeci KariukiHaizhen A ZhongAudra KippesYipeng Sui

physiologyliver physiologypharmacologyintestinal cholesterol uptakehematologyendocrine researchsecondary metabolismendocrinologyhepatologycomparative endocrinologyhealth sciences

Selectivity Studies and Free Energy Calculations of Akt Inhibitors. Molecules (2024)

Haizhen A. ZhongDavid T. Goodwin

medicinal chemistryselectivity studiescomputational chemistrypharmacologyakt inhibitorsfree energy calculations

Targeting the Egfr/Ras/Raf Signaling Pathway in Anticancer Research: A Recent Update on Inhibitor Design and Clinical Trials (2020–2023). Expert Opinion on Therapeutic Patents (2024)

Rima HajjoDima A. SabbahSanaa K. BardaweelHaizhen A. Zhong

tumor targetingmedicineinhibitor designmolecular cancerpharmaceutical researchanticancer researchcancer researchdrug targetingcancer treatmentlung cancersignaling pathwaysreceptorsenzyme inhibitionpharmacologyradiation oncologypharmacotherapyoncologyclinical researchmedicinal researchcellular therapy

Binding and Selectivity Studies of Phosphatidylinositol 3-Kinase (Pi3K) Inhibitors. Journal of Molecular Graphics and Modelling (2023)

Mohammad Al HasanMatthew SabirianovGrace RedwineKaitlin GoettschStephen X. YangHaizhen A. Zhong

medicinal chemistryprotein chemistrypharmacologyselectivity studiesprotein modelingfunctional selectivitymolecular modellingmolecular pharmacologydrug discoverymolecular biologyprotein sciencebiochemistry

Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A1 and A3 Adenosine Receptors. Pharmaceuticals (2023)

Luke J. HamiltonMahesh PattabiramanHaizhen A. ZhongMichaela WalkerHilary VaughnSurabhi Chandra

medicinal chemistrymedicinereceptorspharmacologypharmaceutical chemistrycis-trans curcumincurcumin stereoisomerpharmaceutical researchadenosine receptorsdrug discoverynovel ligandpharmaceutical sciencesneuroscience

Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors. International Journal of Molecular Sciences (2023)

Haizhen A. ZhongSuliman Almahmoud

immunologymedicinal chemistryreceptorsenzyme inhibitionpharmacologypharmaceutical chemistryprotein chemistryselectivity studiesmolecular sciencemolecular pharmacologyenzymesmolecular dockingdrug discoverymolecular biology

Targeting Brd4 and Pi3K Signaling Pathways for the Treatment of Medulloblastoma. Journal of Controlled Release (2023)

Bharti SethiVirender KumarThilina D JayasingheYuxiang DongDonald R RonningHaizhen A ZhongDonald W CoulterRam I Mahato

signaling pathwaysmedicinetumor targetingpharmacologycontrolled releasebiomedical engineeringcancer carecancer researchcell signalingcancer immunotherapycellular therapyanti-cancer agentsoncologymedicinal researchcancer treatmentcancer biologydrug delivery

A Novel Curcumin Isomer, Cis‐Trans Curcumin, Activates Adenosine Receptor Subtypes a 1 and a 3: Potential for Pain Therapy. The FASEB Journal (2022)

Luke J. HamiltonHilary VaughnMahesh PattabiramanHaizhen A. ZhongBrandon LuedtkeSurabhi Chandra

physiologymedicinal chemistryreceptorspain managementpharmacologyadenosine receptorpain therapycell signalingpain researchpharmacotherapysignal transductionneuroscience

Molecular Modeling of Allosteric Site of Isoform-Specific Inhibition of the Peroxisome Proliferator-Activated Receptor Pparγ. Biomolecules (2022)

Suliman AlmahmoudHaizhen A. Zhong

molecular modelingmolecular modellingallosteric sitebiomolecular engineeringmolecular biologystructural molecular biologyisoform-specific inhibitionstructural biologyprotein sciencemembrane biologymolecular physiologybiochemistry

An Updated Review on Betacoronavirus Viral Entry Inhibitors: Learning From Past Discoveries to Advance Covid-19 Drug Discovery. Current Topics in Medicinal Chemistry (2021)

Dima A. SabbahRima HajjoSanaa K. BardaweelHaizhen A. Zhong

medicinal chemistrymedicinepharmacologycovid-19pharmaceutical researchdrug discoveryupdated reviewpast discoveriesmedicinal researchpharmaceutical sciencesantiviral drug developmenttranslational medicine

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H. Andy Zhong

Ralph Wardle Diamond Professor Interim Department Chair

University of Nebraska at Omaha

Affiliations

College of Arts and Sciences

Chemistry

H. Andy Zhong is currently serving as a Chemistry Ralph Wardle Diamond Professor Interim Department Chair at University of Nebraska At Omaha.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

H. Andy Zhong

University of Nebraska at Omaha

Ralph Wardle Diamond Professor Interim Department Chair

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cannabidiol Promotes Intestinal Cholesterol Uptake Mediated by Pregnane X Receptor. Frontiers in Endocrinology (2024)

Conner BrownWangeci KariukiHaizhen A ZhongAudra KippesYipeng Sui

physiologyliver physiologypharmacologyintestinal cholesterol uptakehematologyendocrine researchsecondary metabolismendocrinologyhepatologycomparative endocrinologyhealth sciences

Selectivity Studies and Free Energy Calculations of Akt Inhibitors. Molecules (2024)

Haizhen A. ZhongDavid T. Goodwin

medicinal chemistryselectivity studiescomputational chemistrypharmacologyakt inhibitorsfree energy calculations

Targeting the Egfr/Ras/Raf Signaling Pathway in Anticancer Research: A Recent Update on Inhibitor Design and Clinical Trials (2020–2023). Expert Opinion on Therapeutic Patents (2024)

Rima HajjoDima A. SabbahSanaa K. BardaweelHaizhen A. Zhong

Binding and Selectivity Studies of Phosphatidylinositol 3-Kinase (Pi3K) Inhibitors. Journal of Molecular Graphics and Modelling (2023)

Mohammad Al HasanMatthew SabirianovGrace RedwineKaitlin GoettschStephen X. YangHaizhen A. Zhong

Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A1 and A3 Adenosine Receptors. Pharmaceuticals (2023)

Luke J. HamiltonMahesh PattabiramanHaizhen A. ZhongMichaela WalkerHilary VaughnSurabhi Chandra

Docking and Selectivity Studies of Covalently Bound Janus Kinase 3 Inhibitors. International Journal of Molecular Sciences (2023)

Haizhen A. ZhongSuliman Almahmoud

Targeting Brd4 and Pi3K Signaling Pathways for the Treatment of Medulloblastoma. Journal of Controlled Release (2023)

Bharti SethiVirender KumarThilina D JayasingheYuxiang DongDonald R RonningHaizhen A ZhongDonald W CoulterRam I Mahato

A Novel Curcumin Isomer, Cis‐Trans Curcumin, Activates Adenosine Receptor Subtypes a 1 and a 3: Potential for Pain Therapy. The FASEB Journal (2022)

Luke J. HamiltonHilary VaughnMahesh PattabiramanHaizhen A. ZhongBrandon LuedtkeSurabhi Chandra

physiologymedicinal chemistryreceptorspain managementpharmacologyadenosine receptorpain therapycell signalingpain researchpharmacotherapysignal transductionneuroscience

Molecular Modeling of Allosteric Site of Isoform-Specific Inhibition of the Peroxisome Proliferator-Activated Receptor Pparγ. Biomolecules (2022)

Suliman AlmahmoudHaizhen A. Zhong

An Updated Review on Betacoronavirus Viral Entry Inhibitors: Learning From Past Discoveries to Advance Covid-19 Drug Discovery. Current Topics in Medicinal Chemistry (2021)

Dima A. SabbahRima HajjoSanaa K. BardaweelHaizhen A. Zhong

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David E. Heppner

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University at Buffalo

future medicinal chemistry

medicinal chemistry

Dr. Wayne Guida

Institution

University of South Florida

pharmacological research

mechanisms of action

Yan Zhang

Institution

Virginia Commonwealth University

psychoactive substance use

world psychiatry

Werner Geldenhuys

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West Virginia University

degenerative disease

neurochemical biomarkers

Glen E. Kellogg

Institution

Virginia Commonwealth University

future medicinal chemistry

molecular docking

Brian Blagg

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future medicinal chemistry

Umesh Desai

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pathology

microbial infection

Ziwei HUANG

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pharmaceutical science

future medicinal chemistry

Richard B. Silverman

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Northwestern University

pharmacology

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Jianfeng Cai

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protein-protein interactions

biomolecular engineering