Faculty

Institution

Unit

Venue

Alexandre Pletnev

Research Assistant Professor

Dartmouth College

Affiliations

Faculty of Arts and Sciences

Department of Chemistry

Alexandre Pletnev is currently serving as a Chemistry Research Assistant Professor at Dartmouth College.

Honors

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Experiences

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Education

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Alexandre Pletnev

Dartmouth College

Research Assistant Professor

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chemistry pharmacology organic chemistry organic synthesis enzyme inhibition tumor biology protein science biochemistry cell biology medicinal chemistry transition metal chemistry membrane biology biological chemistry redox biology cell signaling chemical biology oncology oncogenes cancer cells protein function organometallic catalysis cell death medicinal research molecular cancer synthetic chemistry anti-cancer agents apoptosis cancer biology clinical chemistry cellular therapy biochemical sciences leukemia pharmaceutical chemistry applied chemistry tumor targeting tumor suppressors fungal biology medicinal fungi fungal physiology nicotinamide riboside molecular cell biology cell research catalytic synthesis catalyst activation industrial catalysis catalyst preparation receptor tyrosine kinases host specificity cytokines drug targeting biomolecular interactions fungal diversity functional modification redox signaling hematological malignancies heme signaling molecular substrates protein chemistry biological inorganic chemistry signaling pathways cell regulation mitotic cells functional modules polo-like kinase activities tetrasubstituted olefins ring-closing metathesis efficient ruthenium catalysts carbocycle synthesis caspase-like sites selective inhibitor chymotrypsin-like sites specific inhibition myeloma cells specific cell-permeable inhibitor proteasome trypsin-like sites proteasome inhibitors synthetic organic chemistry organic process research

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Inhibition of Endoglin–Gipc Interaction Inhibits Pancreatic Cancer Cell Growth. (2023)

Krishnendu PalAlexandre A. PletnevShamit K. DuttaEnfeng WangRuizhi ZhaoAradhita BaralVinod Kumar YadavSuruchi AggarwalSoundararajan KrishnaswamyKhalid M. AlkharfyShantanu ChowdhuryMark R. SpallerDebabrata Mukhopadhyay

neurologypharmacologycancer researchenzyme inhibitiontumor biologycell biologypancreatic cancer

Pharmacokinetic Profile of the Synthetic Mu-Opioid Receptor Agonist [Lys7]Dermorphin-Irdye®800Cw and Its Feasibility as a Biomarker for Opioid Use Disorder. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Kimberley S. SamkoeRendall R. StrawbridgeMark R. SpallerAlexandre A. PletnevDennis J. WirthBrook K. ByrdBoyu MengJ. Scott SottosantiScott C. DavisJonathan T. Elliott

pharmacologypharmacokinetic profilebiomarkersneurosciencepharmacokineticsopioid use disorder

Supplementary Figure 2 From Inhibition of Endoglin–Gipc Interaction Inhibits Pancreatic Cancer Cell Growth. (2023)

cancer immunotherapypharmacologyenzyme inhibitionmolecular biologypancreatic cancer

Supplementary Materials and Methods From Inhibition of Endoglin–Gipc Interaction Inhibits Pancreatic Cancer Cell Growth. (2023)

cancer immunotherapypharmacologysupplementary materialscancer researchradiation oncologyanti-cancer agentscellular therapytumor biologyimmunologycancer cellstherapeutic targetspancreatic cancer

Role of Plexind1/Tgfβ Signaling Axis in Pancreatic Ductal Adenocarcinoma Progression Correlates With the Mutational Status of Kras. Cancers (2021)

Sneha VivekanandhanVijay S. MadamsettyRamcharan Singh AngomShamit Kumar DuttaEnfeng WangThomas CaulfieldAlexandre A. PletnevRosanna Upstill-GoddardYan W. AsmannDavid ChangMark R. SpallerDebabrata Mukhopadhyay

cell regulationcancer cellsgeneticscancer biologymolecular cancercancer researchmolecular medicinecancer genomicstumor biologypharmacologygene expressiononcologycancer geneticssignaling pathwayscancer caremutational statusoncogenesmolecular biologymedicinal research

Synthesis and Electronic Properties of a Linearly Fused Anthracene Dimer. Tetrahedron Letters (2020)

Evans O. OnyangoPhilip Z. MannesAlexandre PletnevDevin B. GrangerQianxiang AiChad RiskoJohn E. AnthonyGordon W. Gribble

organic chemistrysynthetic chemistryorganic synthesiselectronic propertiesanthracene dimerchemical synthesischemistry

First-Generation Structure-Activity Relationship Studies of 2,3,4,9-Tetrahydro-1H-Carbazol-1-Amines as Cpxa Phosphatase Inhibitors. Publisher (2019)

Yangxiong LiJessi J. GardnerKatherine R. FortneyInga V. LeusVincent BonifayHelen I. ZgurskayaAlexandre A. PletnevSheng ZhangZhong-Yin ZhangGordon W. GribbleStanley M. SpinolaAdam S. Duerfeldt

medicinal chemistrypharmacologycpxa phosphatase inhibitors

CORRECTION: Cysteine Modification Reveals an Allosteric Inhibitory Site on the Cal Pdz Domain. Bioscience Reports (2018)

Yu ZhaoPatrick R. CushingDavid C. SmithsonMaria PellegriniAlexandre A. PletnevSahar Al-AyyoubiAndrew V. GrassettiScott A. GerberR. Kiplin GuyDean R. Madden

pharmacologymembrane biologyreceptorsgene expressionstructural biologyneuroscienceprotein structureallosteric inhibitory sitemolecular biologycysteine modificationcal pdz domainprotein science

Cysteine Modifiers Suggest an Allosteric Inhibitory Site on the Cal Pdz Domain. Bioscience Reports (2018)

Yu ZhaoPatrick R. CushingDavid C. SmithsonMaria PellegriniAlexandre A. PletnevSahar Al-AyyoubiAndrew V. GrassettiScott A. GerberR. Kiplin GuyDean R. Madden

pharmacologymolecular substratesgene expressionbiological inorganic chemistrystructural biologyprotein structurebiochemistryallosteric inhibitory sitecal pdz domainmolecular neuroscienceimmunologycysteine modifiersenzymesprotein scienceprotein chemistry

Formation of Amines by Heteroatom and Metal Substitution. (2018)

Richard C. LarockAlexandre A. Pletnev

transition metal chemistrymetal substitutioninorganic chemistrychemical synthesischemistry

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Alexandre Pletnev

Research Assistant Professor

Dartmouth College

Affiliations

Faculty of Arts and Sciences

Department of Chemistry

Alexandre Pletnev is currently serving as a Chemistry Research Assistant Professor at Dartmouth College.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alexandre Pletnev

Dartmouth College

Research Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Data From Inhibition of Endoglin–Gipc Interaction Inhibits Pancreatic Cancer Cell Growth. (2023)

neurologypharmacologycancer researchenzyme inhibitiontumor biologycell biologypancreatic cancer

Kimberley S. SamkoeRendall R. StrawbridgeMark R. SpallerAlexandre A. PletnevDennis J. WirthBrook K. ByrdBoyu MengJ. Scott SottosantiScott C. DavisJonathan T. Elliott

pharmacologypharmacokinetic profilebiomarkersneurosciencepharmacokineticsopioid use disorder

Supplementary Figure 2 From Inhibition of Endoglin–Gipc Interaction Inhibits Pancreatic Cancer Cell Growth. (2023)

cancer immunotherapypharmacologyenzyme inhibitionmolecular biologypancreatic cancer

Supplementary Materials and Methods From Inhibition of Endoglin–Gipc Interaction Inhibits Pancreatic Cancer Cell Growth. (2023)

cancer immunotherapypharmacologysupplementary materialscancer researchradiation oncologyanti-cancer agentscellular therapytumor biologyimmunologycancer cellstherapeutic targetspancreatic cancer

Role of Plexind1/Tgfβ Signaling Axis in Pancreatic Ductal Adenocarcinoma Progression Correlates With the Mutational Status of Kras. Cancers (2021)

Synthesis and Electronic Properties of a Linearly Fused Anthracene Dimer. Tetrahedron Letters (2020)

Evans O. OnyangoPhilip Z. MannesAlexandre PletnevDevin B. GrangerQianxiang AiChad RiskoJohn E. AnthonyGordon W. Gribble

organic chemistrysynthetic chemistryorganic synthesiselectronic propertiesanthracene dimerchemical synthesischemistry

First-Generation Structure-Activity Relationship Studies of 2,3,4,9-Tetrahydro-1H-Carbazol-1-Amines as Cpxa Phosphatase Inhibitors. Publisher (2019)

Yangxiong LiJessi J. GardnerKatherine R. FortneyInga V. LeusVincent BonifayHelen I. ZgurskayaAlexandre A. PletnevSheng ZhangZhong-Yin ZhangGordon W. GribbleStanley M. SpinolaAdam S. Duerfeldt

medicinal chemistrypharmacologycpxa phosphatase inhibitors

CORRECTION: Cysteine Modification Reveals an Allosteric Inhibitory Site on the Cal Pdz Domain. Bioscience Reports (2018)

Yu ZhaoPatrick R. CushingDavid C. SmithsonMaria PellegriniAlexandre A. PletnevSahar Al-AyyoubiAndrew V. GrassettiScott A. GerberR. Kiplin GuyDean R. Madden

pharmacologymembrane biologyreceptorsgene expressionstructural biologyneuroscienceprotein structureallosteric inhibitory sitemolecular biologycysteine modificationcal pdz domainprotein science

Cysteine Modifiers Suggest an Allosteric Inhibitory Site on the Cal Pdz Domain. Bioscience Reports (2018)

Yu ZhaoPatrick R. CushingDavid C. SmithsonMaria PellegriniAlexandre A. PletnevSahar Al-AyyoubiAndrew V. GrassettiScott A. GerberR. Kiplin GuyDean R. Madden

Formation of Amines by Heteroatom and Metal Substitution. (2018)

Richard C. LarockAlexandre A. Pletnev

transition metal chemistrymetal substitutioninorganic chemistrychemical synthesischemistry

1
2
3
4
5
10 / page

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University of Virginia

pharmacology

organic synthesis

Matthew R. Pratt

Institution

University of Southern California

glycosylation

protein science

John Porco

Institution

Boston University

complex synthesis

complex chemical libraries

Daniel Romo

Institution

Baylor University

organic synthesis

chemistry

Eli Chapman

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University of Arizona

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molecular biology

Arun Sharma

Institution

Pennsylvania State University

cancer letter

future medicinal chemistry

Charles E. McKenna

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University of Southern California

future medicinal chemistry

medicinal chemistry

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general chemistry

Richard B. Silverman

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parasite control

malaria