Faculty

Institution

Unit

Venue

Alan Finkelstein

Albert Einstein College of Medicine

Affiliations

Department of Neuroscience

NoneAlan Finkelstein is currently serving as a Neuroscience faculty at Albert Einstein College of Medicine.

Honors

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Experiences

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Education

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Alan Finkelstein

Albert Einstein College of Medicine

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biophysics membrane biology membranes membrane science molecular biology lipids biochemistry membrane proteins membrane transport vascular biology physiology protein science toxins protein transport biophysical chemistry membrane systems membrane permeation electrophysiology planar lipid bilayers structural biology thin lipid membranes biomolecular structure proteinlipid interaction signal transduction molecular physiology liver physiology membrane formation membrane characterization toxinology protein translocation anthrax toxin channel redox biology peptide science membrane process novel interface intracellular trafficking membrane structure biophysical modeling biomolecules bioenergetics selective separation lipid chemistry inhibitory activity diphtheria toxin diphtheria toxin t-domain cellular physiology applied physiology bioelectrochemistry lipid movement biomolecular interactions lipid bilayer membranes planar bilayers anthrax toxin water permeability colicin ia nanoparticle research molecular science applied microbiology biological integrity surface reactivity charge transport disease physiology proton-exchange membrane planar phospholipid bilayers voltage-dependent conductance electrical excitability voltage-dependent channel in vivo systems mitochondrial function anion sensing channel characterization porous membranes human physiology membrane technology catalyst activation voltage-dependent anion-selective channel

Notable Scholarly Works

Notable Federal Grants

Collaborators

Ion Selectivity of the Anthrax Toxin Channel and Its Effect on Protein Translocation. The Journal of General Physiology (2015)

Aviva SchiffmillerDamon AndersonAlan Finkelstein

protein translocationion selectivityanthrax toxin channelphysiology

Mapping the Membrane Topography of the Th6–Th7 Segment of the Diphtheria Toxin T-Domain Channel. The Journal of General Physiology (2015)

Paul K. KienkerZhengyan WuAlan Finkelstein

membrane biologybiophysicsmembranesmembrane topographydisease physiologymembrane proteinstoxinscell biologyphysiology

Topography of the Th5 Segment in the Diphtheria Toxin T-Domain Channel. The Journal of Membrane Biology (2015)

Paul K. KienkerZhengyan WuAlan Finkelstein

membrane biologyreceptorsbiomolecular structurebiophysicsmembrane transportproteinlipid interactionprotein structuregut-organ axismolecular biologymembrane proteinstoxinsmembrane scienceimmunologymembrane systemst-regulatory cellmembranesprotein science

Crucial Role of H322 in the Folding of Diphtheria Toxin T-Domain Into the Open-Channel State. Biophysical Journal (2014)

Mauricio Vargas-UribeMykola V. RodninPaul KienkerAlan FinkelsteinAlexey S. Ladokhin

single molecule biophysicscrucial rolebiomolecular interactionsprotein sciencebiomolecular structurebiophysical modelingbiomolecular engineeringtoxinsvascular biologymolecular biophysicsstructural biologyprotein structurekey sitestructural molecular biologyopen-channel statebiophysicssignal transductionprotein foldingdiphtheria toxin t-domainmolecular biologyprotein misfolding

Ion Conductance of the Stem of the Anthrax Toxin Channel During Lethal Factor Translocation. Journal of Molecular Biology (2014)

Aviva SchiffmillerAlan Finkelstein

lethal factor translocationion conductancebiophysicsanthrax toxin channelbiochemistrymolecular biologymolecular biophysics

Mapping the Membrane Topography of Segments Th6-Th7 and Th8-Th9 in the Diphtheria Toxin T-Domain Channel. Biophysical Journal (2013)

Paul KienkerZhengyan WuAlan Finkelstein

membrane biologybiophysicssignal transductionbiophysical modelingproteinlipid interactionmembrane topographyprotein structuremolecular biologymembrane proteinssystems biologytoxinsmembrane sciencemembrane systemsmembrane characterizationmembranesprotein science

Comparison of Various Methods for Determining Functional Activity of the Diphtheria Toxin T-Domain. Biophysical Journal (2012)

Mykola V. RodninAlexander KyrychenkoPaul K. KienkerOnkar SharmaMauricio Vargas-UribeR. John CollierAlan FinkelsteinAlexey S. Ladokhin

biophysical chemistrytoxinologytoxicological mechanismbioenergeticsprotein scienceinhibitory activitymicrobiologyenvironmental toxicologyvarious methodstoxinsfunctional activitybioanalysistoxicologygene expressionanalytical toxicologycomparative methodsmycotoxin researchbiophysicsdiphtheria toxin t-domainfunctional selectivitysystems biology

Evidence for a Th6-Th7 Transmembrane Hairpin in the Diphtheria Toxin T-Domain Open Channel State. Biophysical Journal (2012)

Paul KienkerZhengyan WuAlan Finkelstein

membrane biologybiomolecular structurebiophysicssignal transductionproteinlipid interactionprotein secretionreceptor tyrosine kinasesprotein structuremolecular biologymembrane proteinssystems biologycell signalingtoxinsbioenergeticsvascular biologybiomolecular interactionsprotein scienceexperimental biophysics

Replacement of C-Terminal Histidines Uncouples Membrane Insertion and Translocation in Diphtheria Toxin T-Domain. Biophysical Journal (2012)

Mauricio Vargas-UribeMykola V. RodninAlexander KyrychenkoPaul KienkerOnkar SharmaR. John CollierAlan FinkelsteinAlexey S. Ladokhin

toxinologyprotein scienceinhibitory activitymembrane biologyhistopathologytoxinsvascular biologymembranesmembrane transportprotein structureantigen processingbiophysicsprotein foldingdiphtheria toxin t-domainmolecular biologymembrane proteinssystems biologymembrane sciencec-terminal histidines uncouplesprotein transport

Tonb-Dependent Transporter Fhua in Planar Lipid Bilayers: Partial Exit of Its Plug From the Barrel. Biochemistry (2012)

Eshwar UdhoKaren S. JakesAlan Finkelstein

membrane biologyplanar lipid bilayersmembrane transportbiochemistrylipidsmolecular biologymembrane proteinsmembrane sciencetonb-dependent transporter fhuavascular biologymembranesintracellular trafficking

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Alan Finkelstein

Albert Einstein College of Medicine

Affiliations

Department of Neuroscience

NoneAlan Finkelstein is currently serving as a Neuroscience faculty at Albert Einstein College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Alan Finkelstein

Albert Einstein College of Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Ion Selectivity of the Anthrax Toxin Channel and Its Effect on Protein Translocation. The Journal of General Physiology (2015)

Aviva SchiffmillerDamon AndersonAlan Finkelstein

protein translocationion selectivityanthrax toxin channelphysiology

Mapping the Membrane Topography of the Th6–Th7 Segment of the Diphtheria Toxin T-Domain Channel. The Journal of General Physiology (2015)

Paul K. KienkerZhengyan WuAlan Finkelstein

membrane biologybiophysicsmembranesmembrane topographydisease physiologymembrane proteinstoxinscell biologyphysiology

Topography of the Th5 Segment in the Diphtheria Toxin T-Domain Channel. The Journal of Membrane Biology (2015)

Paul K. KienkerZhengyan WuAlan Finkelstein

Crucial Role of H322 in the Folding of Diphtheria Toxin T-Domain Into the Open-Channel State. Biophysical Journal (2014)

Mauricio Vargas-UribeMykola V. RodninPaul KienkerAlan FinkelsteinAlexey S. Ladokhin

Ion Conductance of the Stem of the Anthrax Toxin Channel During Lethal Factor Translocation. Journal of Molecular Biology (2014)

Aviva SchiffmillerAlan Finkelstein

lethal factor translocationion conductancebiophysicsanthrax toxin channelbiochemistrymolecular biologymolecular biophysics

Mapping the Membrane Topography of Segments Th6-Th7 and Th8-Th9 in the Diphtheria Toxin T-Domain Channel. Biophysical Journal (2013)

Paul KienkerZhengyan WuAlan Finkelstein

Comparison of Various Methods for Determining Functional Activity of the Diphtheria Toxin T-Domain. Biophysical Journal (2012)

Mykola V. RodninAlexander KyrychenkoPaul K. KienkerOnkar SharmaMauricio Vargas-UribeR. John CollierAlan FinkelsteinAlexey S. Ladokhin

Evidence for a Th6-Th7 Transmembrane Hairpin in the Diphtheria Toxin T-Domain Open Channel State. Biophysical Journal (2012)

Paul KienkerZhengyan WuAlan Finkelstein

Replacement of C-Terminal Histidines Uncouples Membrane Insertion and Translocation in Diphtheria Toxin T-Domain. Biophysical Journal (2012)

Mauricio Vargas-UribeMykola V. RodninAlexander KyrychenkoPaul KienkerOnkar SharmaR. John CollierAlan FinkelsteinAlexey S. Ladokhin

Tonb-Dependent Transporter Fhua in Planar Lipid Bilayers: Partial Exit of Its Plug From the Barrel. Biochemistry (2012)

Eshwar UdhoKaren S. JakesAlan Finkelstein

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