Faculty

Institution

Unit

Venue

Tobias Baumgart

Professor

University of Pennsylvania

Affiliations

School of Engineering and Applied Science

Chemical and Biomolecular Engineering

School of Arts & Sciences

Chemistry

Tobias Baumgart is currently serving as a Chemical And Biomolecular Engineering Professor at University of Pennsylvania.

Honors

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Experiences

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Education

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Tobias Baumgart

University of Pennsylvania

Professor

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biophysics membrane biology structural biology molecular biology protein science molecular biophysics cell biology biochemistry membrane science experimental biophysics membranes nanotechnology lipids cell signaling lipid science proteinlipid interaction membrane transport surface science cellular physiology cellular biochemistry biological macromolecules lipid movement molecular physiology biomolecular structure liver physiology structural molecular biology protein phase separation membrane systems molecular sorting membrane curvature generation molecular science molecular cell biology membrane technology biomolecular interactions colloid chemistry colloidal systems membrane structure biological chemistry interface science lipid chemistry single-molecule detection amphiphilic system membrane characterization line tension membrane tension curvature sorting asymmetric desorption cell research coordination chemistry plo biology supramolecular assemblies cellular biology cellular immune responses cell adhesion fragmentation effect functional modification immunoglobulin e mast cell disorders interfacial studies nanomechanics polymer engineering polymer technology nanobiotechnology fluid phase coexistence mast cells tension-dependent bilayer tubulation nanodisc micelles fluid domains biomembrane models partitioning preferences model membrane systems simple lipid mixtures protein behavior lipid membranes fluorescence probe

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Membrane Mechanical Stress Incurred by Lipid Asymmetry and Lateral Expansion Biases Non-Vesicular Lipid Transport. Biophysical Journal (2026)

biophysicsmembrane systemsproteinlipid interactionmechanobiologymembrane structurebiomedical engineeringmembranesmembrane biologylipidsmembrane sciencelipid movementnon-vesicular lipid transportlipid asymmetrylateral expansionbiomechanicscellular biochemistry

Endophilin–Lamellipodin–Vasp, Key Components in Fast Endophilin–Mediated Endocytosis, Control Actin Polymerization Within Liquid-Like Condensates. Journal of Biological Chemistry (2025)

biophysicscytoskeletonbiomolecular engineeringbiological macromoleculesprotein sciencebiological engineeringmembrane proteinsbiomoleculesbiophysical reviewmolecular motorsprotein foldingcell and molecular biologymembrane biologyprotein engineeringpeptidesbiopolymerscellular biochemistry

Genetic Code Expansion and Enzymatic Modifications as Accessible Methods for Studying Site‐Specific Post‐Translational Modifications of Alpha‐Synuclein and Tau. Protein Science (2025)

geneticsaccessible methodsdegenerative pathologyneurodegenerative diseaseshuntington's diseasedisease gene identificationgenetic code expansionprotein scienceprotein misfoldingsite‐specific post‐translational modificationsprotein engineeringparkinson's diseaseprotein geneticsmolecular neurodegenerationmolecular biologymolecular research

Strategic Modulation of Polarity and Viscosity Sensitivity of Bimane Molecular Rotor-Based Fluorophores for Imaging α-Synuclein. Journal of the American Chemical Society (2025)

Yarra VenkateshKarthik B. NarayanTobias BaumgartE. James Petersson

single molecule biophysicsprotein sciencecomputational imagingnovel imaging methodsmolecular diagnosticsbiomedical imagingbiological imagingstrategic modulationmolecular imagingfluorescencemolecular motorspolarization imagingviscosity sensitivitybiophysicscancer imagingbiomolecular engineeringtranslational imagingsingle-molecule detectionmolecular biologymedical imaging

Asymmetric Crowders and Membrane Morphology at the Nexus of Intracellular Trafficking and Oncology. Mechanobiology in Medicine (2024)

Kshitiz PariharSeung-Hyun B. KoRyan P. BradleyPhillip TaylorN. RamakrishnanTobias BaumgartWei GuoValerie M. WeaverPaul A. JanmeyRavi Radhakrishnan

medicineasymmetric crowderscancer biologymechanobiologyintracellular traffickingmembrane morphology

Cancer Cell Mechanotypes Dependent on Ecm Properties Drive Tumor Progression Through Extracellular Vesicle Production. Biophysical Journal (2024)

Kshitiz PariharJonathan NukpezahPhyoe K. MyintDi-Ao LiuGhmkin HassanTobias BaumgartValerie M. WeaverWei GuoPaul A. JanmeyRavi Radhakrishnan

biophysicstumor biologyoncologycancer biologycell biologycancer cellstumor progressionextracellular vesicle productionecm properties

Fluorescence Imaging of Lamellipodin-Mediated Biomolecular Condensates on Solid Supported Lipid Bilayer Membranes. Methods in enzymology on CD-ROM/Methods in enzymology (2024)

Karthik B. NarayanLaura BaeyensHoney Priya JamesAparna SwainTobias Baumgart

lipid sciencebiomolecular engineeringbiomolecular interactionsmolecular imagingnanotechnologybiological engineeringbiological imaginglamellipodin-mediated biomolecular condensatesmolecular biological methodbiomedical engineeringmembrane biologymembrane technologymembrane scienceenzymatic modificationlipid bilayer membranesstructural biologyfluorescence imaging

Free Energy Calculations for Membrane Morphological Transformations and Insights to Physical Biology and Oncology. Methods in enzymology on CD-ROM/Methods in enzymology (2024)

Kshitiz PariharSeung-Hyun KoRyan BradleyPhillip TaylorN. RamakrishnanTobias BaumgartWei GuoValerie M. WeaverPaul A. JanmeyRavi Radhakrishnan

biophysicsmembrane morphological transformationsphysical biologyphysiologyfree energy calculationsstructural biology

Methyl-β-Cyclodextrin Asymmetrically Extracts Phospholipid From Bilayers, Granting Tunable Control Over Differential Stress in Lipid Vesicles. Soft Matter (2024)

Tyler ReagleYuxin XieZheyuan LiWarner CarneroTobias Baumgart

biophysicslipid sciencemembrane transportlipid vesicleslipid analysiscondensed matterbiomedical engineeringmaterials sciencemembrane biologysoft mattermembranesmembrane sciencegene expressionmembrane structuredifferential stresstunable controlstructural biologymembrane characterization

Phospholipid Chemical Activity is an Accessible Parameter Through Which the Differential Tension and Area-Per-Lipid Values of Real-World Asymmetric Bilayers Can Be Estimated. Biophysical Journal (2024)

Tyler R. ReagleYuxin XieZheyuan LiJason WangTobias Baumgart

accessible parameterreal-world asymmetric bilayerstheoretical biologybiophysical modelingmathematical biosciencemolecular biophysicsbiomedical engineeringmembrane biologyphospholipid chemical activitymedical biophysicsdifferential tensionmathematical biophysicsmathematical biologycomputational biophysicscomputational biologymembrane sciencebiophysical chemistrybiophysicsbiological engineeringexperimental biophysicsarea-per-lipid values

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Tobias Baumgart

Professor

University of Pennsylvania

Affiliations

School of Engineering and Applied Science

Chemical and Biomolecular Engineering

School of Arts & Sciences

Chemistry

Tobias Baumgart is currently serving as a Chemical And Biomolecular Engineering Professor at University of Pennsylvania.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Tobias Baumgart

University of Pennsylvania

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Membrane Mechanical Stress Incurred by Lipid Asymmetry and Lateral Expansion Biases Non-Vesicular Lipid Transport. Biophysical Journal (2026)

Endophilin–Lamellipodin–Vasp, Key Components in Fast Endophilin–Mediated Endocytosis, Control Actin Polymerization Within Liquid-Like Condensates. Journal of Biological Chemistry (2025)

Genetic Code Expansion and Enzymatic Modifications as Accessible Methods for Studying Site‐Specific Post‐Translational Modifications of Alpha‐Synuclein and Tau. Protein Science (2025)

Strategic Modulation of Polarity and Viscosity Sensitivity of Bimane Molecular Rotor-Based Fluorophores for Imaging α-Synuclein. Journal of the American Chemical Society (2025)

Yarra VenkateshKarthik B. NarayanTobias BaumgartE. James Petersson

Asymmetric Crowders and Membrane Morphology at the Nexus of Intracellular Trafficking and Oncology. Mechanobiology in Medicine (2024)

Kshitiz PariharSeung-Hyun B. KoRyan P. BradleyPhillip TaylorN. RamakrishnanTobias BaumgartWei GuoValerie M. WeaverPaul A. JanmeyRavi Radhakrishnan

medicineasymmetric crowderscancer biologymechanobiologyintracellular traffickingmembrane morphology

Cancer Cell Mechanotypes Dependent on Ecm Properties Drive Tumor Progression Through Extracellular Vesicle Production. Biophysical Journal (2024)

Kshitiz PariharJonathan NukpezahPhyoe K. MyintDi-Ao LiuGhmkin HassanTobias BaumgartValerie M. WeaverWei GuoPaul A. JanmeyRavi Radhakrishnan

biophysicstumor biologyoncologycancer biologycell biologycancer cellstumor progressionextracellular vesicle productionecm properties

Fluorescence Imaging of Lamellipodin-Mediated Biomolecular Condensates on Solid Supported Lipid Bilayer Membranes. Methods in enzymology on CD-ROM/Methods in enzymology (2024)

Karthik B. NarayanLaura BaeyensHoney Priya JamesAparna SwainTobias Baumgart

Free Energy Calculations for Membrane Morphological Transformations and Insights to Physical Biology and Oncology. Methods in enzymology on CD-ROM/Methods in enzymology (2024)

Kshitiz PariharSeung-Hyun KoRyan BradleyPhillip TaylorN. RamakrishnanTobias BaumgartWei GuoValerie M. WeaverPaul A. JanmeyRavi Radhakrishnan

biophysicsmembrane morphological transformationsphysical biologyphysiologyfree energy calculationsstructural biology

Methyl-β-Cyclodextrin Asymmetrically Extracts Phospholipid From Bilayers, Granting Tunable Control Over Differential Stress in Lipid Vesicles. Soft Matter (2024)

Tyler ReagleYuxin XieZheyuan LiWarner CarneroTobias Baumgart

Tyler R. ReagleYuxin XieZheyuan LiJason WangTobias Baumgart

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