Faculty

Institution

Unit

Venue

Cyrus Safinya

Distinguished Professor

University of California, Santa Cruz

Affiliations

Baskin School of Engineering

Biomolecular Engineering

Computer Science and Engineering

Physical & Biological Sciences

Molecular, Cell, & Developmental Biology

Physics

Cyrus Safinya is currently serving as a Baskin School Of Engineering Distinguished Professor at University of California, Santa Cruz.

Honors

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Experiences

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Education

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Cyrus Safinya

University of California, Santa Cruz

Distinguished Professor

You can click a keyword to filter the displayed items

biophysics materials science structural biology membrane biology molecular biology biomolecular engineering nanotechnology molecular biophysics gene delivery protein science condensed matter physics surface science experimental biophysics drug delivery nucleic acids structural molecular biology lipid science supramolecular assemblies polymer science membrane science nanoparticle research biomolecular structure condensed matter dna nanotechnology material research nanobiotechnology molecular science biomolecules molecular structure fragmentation effect lipid chemistry x-ray diffraction protein transport molecular biotechnology biopolymers genome biology protein assembly interface science transfection efficiency controlled release molecular cell biology colloid chemistry membrane structure colloidal systems lipid synthesis cationic liposome-dna complexes lipid preparation molecular complexes polymer engineering molecular technology biomolecular interactions drug targeting neurofilament networks biomaterials design nano-drug delivery surface reactivity lipid-dna complexes cationic lipid-dna complexes x-ray surface forces surface functionalization macromolecular science surface characterization peptide engineering molecular self-assembly instrument science amphiphilic system synchrotron x-ray study membrane charge density cationic liposomes direct force measurements smectic liquid crystal two-dimensional smectic ordering hierarchical self-assembly polymer lipids lamellar biogels dual-control release capabilities protein phase separation cancer drug delivery complex fluids biological matter

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cryo-Tem Reveals the Influence of Multivalent Charge and Pegylation on Shape Transitions in Fluid Lipid Assemblies: From Vesicles to Discs, Rods, and Spheres. Langmuir (2023)

Victoria M. SteffesZhening ZhangKai K. EwertCyrus R. Safinya

membrane biologybiophysicsfluid lipid assembliesmolecular biologyshape transitionsmultivalent charge

Divalent Metal Ion Mediated Structural Transitions in Microtubule Bundles in Dissipative Reaction Mixtures Revealed by Synchrotron Saxs and Plastic-Embedded Tem. Biophysical Journal (2023)

Phillip A. KohlChaeyeon SongBretton FletcherRebecca BestChristine TchounwouXimena Garcia ArceoPeter J. ChungHerbert P. MillerLeslie WilsonStuart C. FeinsteinCyrus R. Safinya

divalent metal ionplastic-embedded tembiophysicsstructural biologystructural transitionsmedical biophysicsneurosciencedissipative reaction mixturescondensed mattercell biologyexperimental biophysicsprotein sciencemicrotubule bundlesmolecular biophysics

Fusion Between Bare Liposomes and Exosomes is Enhanced Through Induced Depletion Attraction or in Acidic Conditions. Biophysical Journal (2023)

WS FisherKK EwertCR Safinya

fusionbiophysical chemistrymembrane biologybiophysicsacidic conditionsinduced depletion attractioncell biologybare liposomesphysiology

Lipids With Negative Spontaneous Curvature Decrease the Solubility of the Cancer Drug Paclitaxel in Liposomes. The European Physical Journal E (2023)

Victoria SteffesScott MacDonaldJohn CroweMeena MuraliKai K. EwertYouli LiCyrus R. Safinya

condensed mattermembrane biologyliver cancerneurosciencesoft mattervascular biologymembranespharmacologylipid analysisoncologyredox biologylipidscancer drug paclitaxellipid chemistrynegative spontaneous curvaturebiophysicsclinical lipidologylipid sciencelipid synthesismedicinal research

Miniaturized Hybrid Materials Inspired by Nature (Final Technical Report). (2023)

CR SafinyaY LiKK Ewert

materials sciencehybrid materialsminiaturizationadvanced materials

Synchrotron X-Ray Study of Intrinsically Disordered and Polyampholytic Tau 4Rs and 4Rl Under Controlled Ionic Strength. The European Physical Journal E (2023)

Hasaeam ChoJimin LeeHanjoon NhoKeunmin LeeBopil GimJuncheol LeeJaehee LeeKai K. EwertYouli LiStuart C. FeinsteinCyrus R. SafinyaKyeong Sik JinMyung Chul Choi

materials sciencebiophysicscondensed matter physicssynchrotron x-ray studyneurosciencesoft mattercondensed matterionic strength

Complexes of Tubulin Oligomers and Tau Form an Intervening Network Cross-Bridging Microtubules Into Bundles. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Phillip KohlChaeyeon SongBretton FletcherRebecca L. BestChristine TchounwouXimena Garcia ArceoPeter J. ChungHerbert P. MillerLeslie WilsonMyung Chul ChoiYouli LiStuart C. FeinsteinCyrus R. Safinya

geneticstubulin oligomersmembrane biologytau formstructural biologybiological networksneurosciencemolecular biologymolecular neuroscienceprotein science

Divalent Cations Induce Non-Equilibrium Phase Transitions in Tau-Mediated Microtubule Bundles Undergoing Dynamic Instability. Biophysical Journal (2022)

Bretton FletcherPhillip A. KohlChaeyeon SongPeter J. ChungHerbert P. MillerYouli LiMyung Chul ChoiLeslie WilsonStuart C. FeinsteinCyrus R. Safinya

biophysicstau-mediated microtubule bundlesneurosciencedivalent cationsnon-equilibrium phase transitionscell biologyexperimental biophysicsdynamic instabilitymolecular biophysics

Exosomes Are Promising Vectors for Hydrophobic Drug Delivery to Human Cancer Cells. Biophysical Journal (2022)

William S. FisherChristine TchounwouSophia WeiLogan RobertsKai K. EwertCyrus R. Safinya

nanomedicinetumor targetingcancer cellsbiophysicscancer researchmolecular medicineoncologymedical biophysicscancer genomicsdrug deliveryhydrophobic drug deliverycellular therapyhuman cancer cellscell biologybiomedical engineering

Paclitaxel-Loaded Cationic Fluid Lipid Nanodiscs and Liposomes With Brush-Conformation Peg Chains Penetrate Breast Tumors and Trigger Caspase-3 Activation. ACS Applied Materials & Interfaces (2022)

Lorena Simón-GraciaPablo ScodellerWilliam S. FisherValeria SidorenkoVictoria M. SteffesKai K. EwertCyrus R. SafinyaTambet Teesalu

nanotechnologytumor targetingapplied physicsnanoparticle researchsurface nanotechnologydrug targetsmetastasismaterial researchbreast tumorsmaterials sciencebreast cancerbreast oncologybrush-conformation peg chainscancer immunotherapytherapeutic nanomaterialsmembrane scienceadvanced materialsmedicinal researchbiomedical engineeringinterface science

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Cyrus Safinya

Distinguished Professor

University of California, Santa Cruz

Affiliations

Baskin School of Engineering

Biomolecular Engineering

Computer Science and Engineering

Physical & Biological Sciences

Molecular, Cell, & Developmental Biology

Physics

Cyrus Safinya is currently serving as a Baskin School Of Engineering Distinguished Professor at University of California, Santa Cruz.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Cyrus Safinya

University of California, Santa Cruz

Distinguished Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cryo-Tem Reveals the Influence of Multivalent Charge and Pegylation on Shape Transitions in Fluid Lipid Assemblies: From Vesicles to Discs, Rods, and Spheres. Langmuir (2023)

Victoria M. SteffesZhening ZhangKai K. EwertCyrus R. Safinya

membrane biologybiophysicsfluid lipid assembliesmolecular biologyshape transitionsmultivalent charge

Divalent Metal Ion Mediated Structural Transitions in Microtubule Bundles in Dissipative Reaction Mixtures Revealed by Synchrotron Saxs and Plastic-Embedded Tem. Biophysical Journal (2023)

Phillip A. KohlChaeyeon SongBretton FletcherRebecca BestChristine TchounwouXimena Garcia ArceoPeter J. ChungHerbert P. MillerLeslie WilsonStuart C. FeinsteinCyrus R. Safinya

Fusion Between Bare Liposomes and Exosomes is Enhanced Through Induced Depletion Attraction or in Acidic Conditions. Biophysical Journal (2023)

WS FisherKK EwertCR Safinya

fusionbiophysical chemistrymembrane biologybiophysicsacidic conditionsinduced depletion attractioncell biologybare liposomesphysiology

Lipids With Negative Spontaneous Curvature Decrease the Solubility of the Cancer Drug Paclitaxel in Liposomes. The European Physical Journal E (2023)

Victoria SteffesScott MacDonaldJohn CroweMeena MuraliKai K. EwertYouli LiCyrus R. Safinya

Miniaturized Hybrid Materials Inspired by Nature (Final Technical Report). (2023)

CR SafinyaY LiKK Ewert

materials sciencehybrid materialsminiaturizationadvanced materials

Synchrotron X-Ray Study of Intrinsically Disordered and Polyampholytic Tau 4Rs and 4Rl Under Controlled Ionic Strength. The European Physical Journal E (2023)

Hasaeam ChoJimin LeeHanjoon NhoKeunmin LeeBopil GimJuncheol LeeJaehee LeeKai K. EwertYouli LiStuart C. FeinsteinCyrus R. SafinyaKyeong Sik JinMyung Chul Choi

materials sciencebiophysicscondensed matter physicssynchrotron x-ray studyneurosciencesoft mattercondensed matterionic strength

Complexes of Tubulin Oligomers and Tau Form an Intervening Network Cross-Bridging Microtubules Into Bundles. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Phillip KohlChaeyeon SongBretton FletcherRebecca L. BestChristine TchounwouXimena Garcia ArceoPeter J. ChungHerbert P. MillerLeslie WilsonMyung Chul ChoiYouli LiStuart C. FeinsteinCyrus R. Safinya

geneticstubulin oligomersmembrane biologytau formstructural biologybiological networksneurosciencemolecular biologymolecular neuroscienceprotein science

Divalent Cations Induce Non-Equilibrium Phase Transitions in Tau-Mediated Microtubule Bundles Undergoing Dynamic Instability. Biophysical Journal (2022)

Bretton FletcherPhillip A. KohlChaeyeon SongPeter J. ChungHerbert P. MillerYouli LiMyung Chul ChoiLeslie WilsonStuart C. FeinsteinCyrus R. Safinya

biophysicstau-mediated microtubule bundlesneurosciencedivalent cationsnon-equilibrium phase transitionscell biologyexperimental biophysicsdynamic instabilitymolecular biophysics

Exosomes Are Promising Vectors for Hydrophobic Drug Delivery to Human Cancer Cells. Biophysical Journal (2022)

William S. FisherChristine TchounwouSophia WeiLogan RobertsKai K. EwertCyrus R. Safinya

Paclitaxel-Loaded Cationic Fluid Lipid Nanodiscs and Liposomes With Brush-Conformation Peg Chains Penetrate Breast Tumors and Trigger Caspase-3 Activation. ACS Applied Materials & Interfaces (2022)

Lorena Simón-GraciaPablo ScodellerWilliam S. FisherValeria SidorenkoVictoria M. SteffesKai K. EwertCyrus R. SafinyaTambet Teesalu

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