Faculty

Institution

Unit

Venue

Adriano Marchese

Professor; Program Director Biochemistry Graduate Program; Director Interdisciplinary Doctoral Program in Biomedical Sciences IDP

Medical College of Wisconsin

Affiliations

Biochemistry

Adriano Marchese is currently serving as a Biochemistry Professor; Program Director Biochemistry Graduate Program; Director Interdisciplinary Doctoral Program in Biomedical Sciences IDP at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Adriano Marchese

Medical College of Wisconsin

Professor; Program Director Biochemistry Graduate Program; Director Interdisciplinary Doctoral Program in Biomedical Sciences IDP

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molecular biology biochemistry receptors cell signaling protein science signal transduction g protein-coupled receptor receptor (biochemistry) cell biology gene expression biological chemistry pharmacology molecular cell biology molecular and cellular biology medicinal research structural molecular biology intracellular trafficking structural biology signaling pathways chemical biology molecular pharmacology molecular regulation cancer cells protein transport biomolecular interactions cell trafficking receptor tyrosine kinases molecular physiology biochemical sciences enzyme inhibition endocytic pathway dopamine cytokines molecular science redox biology cancer discovery oncogenes addiction biology neuropeptide receptors neuropeptides host specificity inhibitory activity molecular immunology cellular biology transcription regulation biochemical interaction chromosomal mapping endosomal sorting complex chemokine receptors endosomal sorting developmental cell developmental science embryonic development developmental genetics molecular research cytogenetics gene characterization biochemical genetics pathway analysis genomic mechanisms biological function molecular evidence mitochondrial biogenesis mitophagy agonist-promoted ubiquitination ligand-induced ubiquitination chromosomal localization novel genes somatostatin receptors extracellular ubiquitin cell surface receptor human genes mitochondria-targeted drugs transport machinery novel human genes clathrin-dependent internalization cell migration immunology cellular physiology cancer research cancer biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cxcl12 Chemokine Dimer Signaling Modulates Acute Myelogenous Leukemia Cell Migration Through Altered Receptor Internalization. Scientific Reports (2025)

cxcl12 chemokine dimertumor biologycancer researchhematological malignanciescancer biologycell biologycell signalingleukemiacancer cellsreceptor internalizationimmunologysignal transductionmyeloid neoplasia

Distinct Membrane Binding Properties of the Two Non-Visual Arrestins. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Thomas D. KilleenKatelyn TepperKyle W. MillerYasmin AydinYa ZhuoShuaitong ZhaoJason M. ConleyRachel TatCandice KlugAdriano MarcheseValerică RaicuQiuyan Chen

biophysicsmembrane systemsdistinct membranemembrane proteinsbiochemistrymembrane biologymembranesmolecular biologynon-visual arrestins

Cxcl12 Chemokine Dimer Signaling Modulates Acute Myelogenous Leukemia Cell Migration Through Altered Receptor Internalization. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Donovan DrouillardMichael HalykoElizabeth CinquegraniDonna McAllisterFrancis C. PetersonAdriano MarcheseMichael B. Dwinell

receptorssignaling pathwayshematological malignanciescancer biologycell biologycell signalingleukemiareceptor internalizationsystems biologycytokinesmolecular biology

Receptor Determinants for ß-Arrestin Functional Specificity at C-X-C Chemokine Receptor 5 (Cxcr5). Molecular Pharmacology (2024)

Joseph M CreceliusAaren R ManzSara BenzowAdriano Marchese

receptorsss-arrestin functional specificityreceptor determinantspharmacologymolecular pharmacology

Snx9 Family Mediates βArrestin-Independent Gpcr Endocytosis. Communications Biology (2024)

Valeria L. RobletoYa ZhuoJoseph M. CreceliusSara BenzowAdriano Marchese

stem cell researchgene expressionmolecular and cellular biologyendocytic pathwaymolecular cell biologycell signalingprotein scienceg protein-coupled receptorbiologybiochemistryvascular biologysignal transductionmolecular biologybarrestin-independent gpcr endocytosisdisease progressionmolecular medicinevirus research

Proximity Labeling to Identify β-Arrestin1 Binding Partners Downstream of Ligand-Activated G Protein-Coupled Receptors. International Journal of Molecular Sciences (2023)

Ya ZhuoValeria L. RobletoAdriano Marchese

receptorsreceptor (biochemistry)downstream processingmolecular sciencepartners downstreamprotein sciencecell signalingmolecular dockingstructural molecular biologyprotein structuresystems biologybiochemistryprotein foldingg protein-coupled receptorsignal transductionsingle-molecule detectionmolecular biologymedicinal research

Regulation of Gpcr Signaling by Sorting Nexins. Journal of Pharmacology and Experimental Therapeutics (2023)

Valeria RobletoYa ZhuoJoseph CreceliusAdriano Marchese

protein sciencecell signalinggpcr signalingmolecular regulationpharmacologymolecular sortinggene expressiong protein-coupled receptorsystems biologydrug discoveryneuropharmacologymolecular cell biologylate bindingvascular biologymedicinal researchsignaling pathwayssignal transductionmolecular biologyenzyme inhibition

Targeting Cxcr4 Abrogates Resistance to Trastuzumab by Blocking Cell Cycle Progression and Synergizes With Docetaxel in Breast Cancer Treatment. Breast Cancer Research (2023)

Shuying LiuShelly M. XieWenbin LiuMihai GageaAriella B. HankerNguyen NguyenAkshara Singareeka RaghavendraGloria Yang-KolodjiFuliang ChuSattva S. NeelapuAdriano MarcheseSamir HanashJohann ZimmermannCarlos L. ArteagaDebasish Tripathy

cancer immunotherapycell biologytumor biologycellular therapyoncologycancer researchsystems biologybreast cancer treatmentcancer treatmentcancer discoverytherapy resistancenovel therapiesbreast cancergynecologic oncologydrug treatmentbiomolecular engineeringcancer cellsoncogenescell cycle progressiontreatment development

Β-Arrestin1 Directs Substrate Lysine Selection and Linkage Type Specificity by E3 Ubiquitin Ligases. Journal of Pharmacology and Experimental Therapeutics (2023)

Chandler McElrathYa ZhuoSara BenzowAdriano Marchese

linkage type specificitylink typepharmacologypharmacological research

Β-Arrestin1 is an E3 Ubiquitin Ligase Adaptor for Substrate Linear Polyubiquitination. Journal of Biological Chemistry (2023)

Chandler J. McElrathSara BenzowYa ZhuoAdriano Marchese

molecular and cellular biologysystems biologybiochemistrybiological chemistrymolecular biologysubstrate linear polyubiquitination

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Adriano Marchese

Professor; Program Director Biochemistry Graduate Program; Director Interdisciplinary Doctoral Program in Biomedical Sciences IDP

Medical College of Wisconsin

Affiliations

Biochemistry

Honors

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Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Adriano Marchese

Medical College of Wisconsin

Professor; Program Director Biochemistry Graduate Program; Director Interdisciplinary Doctoral Program in Biomedical Sciences IDP

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cxcl12 Chemokine Dimer Signaling Modulates Acute Myelogenous Leukemia Cell Migration Through Altered Receptor Internalization. Scientific Reports (2025)

Distinct Membrane Binding Properties of the Two Non-Visual Arrestins. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Thomas D. KilleenKatelyn TepperKyle W. MillerYasmin AydinYa ZhuoShuaitong ZhaoJason M. ConleyRachel TatCandice KlugAdriano MarcheseValerică RaicuQiuyan Chen

biophysicsmembrane systemsdistinct membranemembrane proteinsbiochemistrymembrane biologymembranesmolecular biologynon-visual arrestins

Cxcl12 Chemokine Dimer Signaling Modulates Acute Myelogenous Leukemia Cell Migration Through Altered Receptor Internalization. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Donovan DrouillardMichael HalykoElizabeth CinquegraniDonna McAllisterFrancis C. PetersonAdriano MarcheseMichael B. Dwinell

receptorssignaling pathwayshematological malignanciescancer biologycell biologycell signalingleukemiareceptor internalizationsystems biologycytokinesmolecular biology

Receptor Determinants for ß-Arrestin Functional Specificity at C-X-C Chemokine Receptor 5 (Cxcr5). Molecular Pharmacology (2024)

Joseph M CreceliusAaren R ManzSara BenzowAdriano Marchese

receptorsss-arrestin functional specificityreceptor determinantspharmacologymolecular pharmacology

Snx9 Family Mediates βArrestin-Independent Gpcr Endocytosis. Communications Biology (2024)

Valeria L. RobletoYa ZhuoJoseph M. CreceliusSara BenzowAdriano Marchese

Proximity Labeling to Identify β-Arrestin1 Binding Partners Downstream of Ligand-Activated G Protein-Coupled Receptors. International Journal of Molecular Sciences (2023)

Ya ZhuoValeria L. RobletoAdriano Marchese

Regulation of Gpcr Signaling by Sorting Nexins. Journal of Pharmacology and Experimental Therapeutics (2023)

Valeria RobletoYa ZhuoJoseph CreceliusAdriano Marchese

Targeting Cxcr4 Abrogates Resistance to Trastuzumab by Blocking Cell Cycle Progression and Synergizes With Docetaxel in Breast Cancer Treatment. Breast Cancer Research (2023)

Β-Arrestin1 Directs Substrate Lysine Selection and Linkage Type Specificity by E3 Ubiquitin Ligases. Journal of Pharmacology and Experimental Therapeutics (2023)

Chandler McElrathYa ZhuoSara BenzowAdriano Marchese

linkage type specificitylink typepharmacologypharmacological research

Β-Arrestin1 is an E3 Ubiquitin Ligase Adaptor for Substrate Linear Polyubiquitination. Journal of Biological Chemistry (2023)

Chandler J. McElrathSara BenzowYa ZhuoAdriano Marchese

molecular and cellular biologysystems biologybiochemistrybiological chemistrymolecular biologysubstrate linear polyubiquitination

1
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7
10 / page

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