Faculty

Institution

Unit

Venue

Xuedong Liu

Professor

University of Colorado Boulder

Affiliations

Natural Sciences

Biochemistry Department

College of Arts and Sciences

Natural Sciences

Xuedong Liu is currently serving as a Biochemistry Professor at University of Colorado Boulder.

Honors

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Experiences

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Education

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Xuedong Liu

University of Colorado Boulder

Professor

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molecular biology cell biology biochemistry gene expression cell signaling signal transduction genetics molecular and cellular biology protein science molecular cell biology enzyme inhibition cell regulation signaling pathways biological chemistry medicinal research cellular biology cell and molecular biology gene regulation tumor biology protein phosphorylation membrane biology transcription factors oncogenes molecular regulation cellular physiology cancer biology genome biology mammalian biology mitochondrial dynamics mitochondrial function tgf-b signaling redox biology cell research structural molecular biology molecular physiology theoretical biology transcription regulation protein function intracellular trafficking cell cycle molecular biological method molecular science biochemical sciences gene function cancer genetics cell migration receptor (biochemistry) mitophagy mammalian cells cell growth cell proliferation angiogenesis mutagenesis bioconjugation gene transfer cancer genomics epigenomics tumor suppressors integrative biology biophysical modeling developmental genetics cell trafficking structural basis growth inhibition epithelial cells transcriptional induction synergistic cooperation smad proteins tgf-b-induced transcription targeted mutation ski oncoprotein growth factor systematic identification mrna targets protein kinases novel mechanism

Notable Scholarly Works

Notable Federal Grants

Collaborators

Histone Deacetylase Inhibitor Largazole Deactivates a Subset of Superenchancers and Causes Mitotic Chromosome Mis-Alignment by Suppressing Sp1 and Brd4. bioRxiv (Cold Spring Harbor Laboratory) (2025)

molecular and cellular biologycell cyclechromatin remodelingnucleic acidsepigeneticscell biologychromosome biologycell divisionchromosomal rearrangementsmolecular geneticsmolecular cell biologymolecular biologychromatindna repairgenetics

Chandipura Viral Glycoprotein (Cnv-G) Promotes Gectosome Generation and Enables Delivery of Intracellular Therapeutics. Molecular Therapy (2024)

Xiaojuan ZhangQuanbin XuZeyu LiuJayson B. BallBrandon BlackSaheli GangulyMichael E. HarlandSamuel BlackmanStephanie BryantKristi AnsethLinda WatkinsXuedong Liu

chandipura viral glycoproteinvirologyimmunologyviral oncologyintracellular therapeuticspharmacologymedicinegectosome generation

Cloflucarban Illuminates Specificity and Context-Dependent Activation of the Pink1–Parkin Pathway by Mitochondrial Complex Inhibition. Biomolecules (2024)

Adrian T. RamirezZeyu LiuQuanbin XuSarah NowosadtkoXuedong Liu

molecular and cellular biologycontext-dependent activationbiomoleculesbiomolecular interactionsstructural molecular biologymolecular biologymitochondrial complex inhibitiongene expressionsecretory pathwaymedicinal researchbiochemistrypathway analysisprotein structuresystems biologystructural biologymitochondrial dynamicsmolecular cell biologymitochondrial functionsignal transductionenzyme inhibition

Liebig’s Law of the Minimum in the Tgf-β/Smad Pathway. PLoS Computational Biology (2024)

Yuchao LiDifan DengChris Tina HöferJihye KimWon Do HeoQuanbin XuXuedong LiuZhike Zi

computational biologymathematical biosciencetheoretical biologyprotein sciencebioinformaticsmathematical biologyscientific computingsignaling pathwaysmolecular informaticsstructural bioinformaticspathway analysismolecular biologyquantitative biologycomputational biophysicssystems biologybiophysical modelinggene expressionbiomolecular engineering

Author Reply to Peer Reviews of Liebig's Law of the Minimum in the Tgf-β/Smad Pathway. (2023)

Yuchao LiDifan DengChris Tina HöferJihye KimWon Do HeoQuanbin XuXuedong LiuZhike Zi

transcription factorspathway analysismolecular biologysystems biologybiomolecular engineering

Compositions and Methods for the Development of Tumor Metastasis and Horizontal Gene Transfer. WO2023091964A2 (2023)

oncogenesmetastasistumor biologyhorizontal gene transfertumor metastasiscell biologydevelopmental biologycarcinogenesiscancer researchcancer cellstumor heterogeneitycancer biology

Data From Preclinical Development of the Class-I–Selective Histone Deacetylase Inhibitor Oki-179 for the Treatment of Solid Tumors. (2023)

Jennifer R. DiamondTodd M. PittsDana UngermannovaChristopher G. NasveschukGan ZhangAndrew J. PhillipsStacey M. BagbyJessica PaffordBetelehem W. YacobTimothy P. NewtonJohn J. TentlerBrian GittlemanSarah J. HartmanJohn A. DeMatteiJames D. WinklerMichael K. WendtWilliam P. SchiemannS. Gail EckhardtXuedong LiuAnthony D. Piscopio

radiation oncologytumor targetinganti-cancer agentsmedicinal researchcellular therapycancer researchpreclinical developmentsolid tumorspharmacologycancer managementcancer treatmentenzyme inhibitionhealth sciencesoncology

Cell Type-Specific Intercellular Gene Transfer in Mammalian Cells via Transient Cell Entrapment. Cell Discovery (2022)

Quanbin XuXiaojuan ZhangGilson J. SanchezAdrian T. RamirezXuedong Liu

molecular and cellular biologymammalian cellscell biologytransient cell entrapmentcell traffickingbiologymammalian biologycellular biologyintercellular communicationsystems biologycell researchgene transfercell migrationcell and molecular biology

Combined Inhibition of Histone Deacetylases and Bromodomain Proteins Normalizes Persistent Activation of Pulmonary Hypertensive Adventitial Fibroblasts. (2022)

H. ZhangA. LauxM. LiX.-D. LiuN.W. MorrellC.-J. HuK.R. Stenmark

cardiovascular diseasepulmonary vascular diseaseautophagypharmacologyvascular biologyepigeneticscell biologypulmonary pharmacologybiomolecular engineeringfibrosiscardiologyrespiratory medicinemedicinal researchhistone deacetylasescardiovascular researchpulmonary circulationpulmonary arterial hypertensionchromatinhypertension

Learning Anisotropic Interaction Rules From Individual Trajectories in a Heterogeneous Cellular Population. Journal of The Royal Society Interface (2022)

Daniel A. MessengerGraycen E. WheelerXuedong LiuDavid M. Bortz

biophysicsanisotropic interaction rulestheoretical biologymathematical biologycell biologyindividual trajectoriessystems biologyheterogeneous cellular population

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Xuedong Liu

Professor

University of Colorado Boulder

Affiliations

Natural Sciences

Biochemistry Department

College of Arts and Sciences

Natural Sciences

Xuedong Liu is currently serving as a Biochemistry Professor at University of Colorado Boulder.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Xuedong Liu

University of Colorado Boulder

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Chandipura Viral Glycoprotein (Cnv-G) Promotes Gectosome Generation and Enables Delivery of Intracellular Therapeutics. Molecular Therapy (2024)

Xiaojuan ZhangQuanbin XuZeyu LiuJayson B. BallBrandon BlackSaheli GangulyMichael E. HarlandSamuel BlackmanStephanie BryantKristi AnsethLinda WatkinsXuedong Liu

chandipura viral glycoproteinvirologyimmunologyviral oncologyintracellular therapeuticspharmacologymedicinegectosome generation

Cloflucarban Illuminates Specificity and Context-Dependent Activation of the Pink1–Parkin Pathway by Mitochondrial Complex Inhibition. Biomolecules (2024)

Adrian T. RamirezZeyu LiuQuanbin XuSarah NowosadtkoXuedong Liu

Liebig’s Law of the Minimum in the Tgf-β/Smad Pathway. PLoS Computational Biology (2024)

Yuchao LiDifan DengChris Tina HöferJihye KimWon Do HeoQuanbin XuXuedong LiuZhike Zi

Author Reply to Peer Reviews of Liebig's Law of the Minimum in the Tgf-β/Smad Pathway. (2023)

Yuchao LiDifan DengChris Tina HöferJihye KimWon Do HeoQuanbin XuXuedong LiuZhike Zi

transcription factorspathway analysismolecular biologysystems biologybiomolecular engineering

Compositions and Methods for the Development of Tumor Metastasis and Horizontal Gene Transfer. WO2023091964A2 (2023)

oncogenesmetastasistumor biologyhorizontal gene transfertumor metastasiscell biologydevelopmental biologycarcinogenesiscancer researchcancer cellstumor heterogeneitycancer biology

Data From Preclinical Development of the Class-I–Selective Histone Deacetylase Inhibitor Oki-179 for the Treatment of Solid Tumors. (2023)

Cell Type-Specific Intercellular Gene Transfer in Mammalian Cells via Transient Cell Entrapment. Cell Discovery (2022)

Quanbin XuXiaojuan ZhangGilson J. SanchezAdrian T. RamirezXuedong Liu

Combined Inhibition of Histone Deacetylases and Bromodomain Proteins Normalizes Persistent Activation of Pulmonary Hypertensive Adventitial Fibroblasts. (2022)

H. ZhangA. LauxM. LiX.-D. LiuN.W. MorrellC.-J. HuK.R. Stenmark

Learning Anisotropic Interaction Rules From Individual Trajectories in a Heterogeneous Cellular Population. Journal of The Royal Society Interface (2022)

Daniel A. MessengerGraycen E. WheelerXuedong LiuDavid M. Bortz

biophysicsanisotropic interaction rulestheoretical biologymathematical biologycell biologyindividual trajectoriessystems biologyheterogeneous cellular population

1
2
3
4
5
12
10 / page

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Boston University

interactomics

biomedical informatics

Donna Zhang

Institution

University of Arizona

toxicology

reactive oxygen specie

Philip A. Cole

Institution

Johns Hopkins University

molecular biology

biochemistry

Michele Pagano, MD

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cell cycle

cell cycle control

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dna damage response

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