Faculty

Institution

Unit

Venue

William Shih

Professor of Biological Chemistry and Molecular Pharmacology

Harvard University

Affiliations

Harvard Medical School

Biological Chemistry and Molecular Pharmacology

William Shih is currently serving as a Biological Chemistry And Molecular Pharmacology Professor of Biological Chemistry and Molecular Pharmacology at Harvard University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William Shih

Harvard University

Professor of Biological Chemistry and Molecular Pharmacology

You can click a keyword to filter the displayed items

nanotechnology dna nanotechnology biomolecular engineering molecular biology materials science nanobiotechnology biological engineering structural biology nucleic acids nanomaterials genetic engineering molecular self-assembly self-assembly membrane biology molecular engineering protein science bioinformatics dna origami structural molecular biology nanometrology supramolecular assemblies genome biology sequence assembly dna computing biomolecular structure structure determination molecular biotechnology surface nanotechnology gene delivery dna nanostructures dna nanoswitch calipers molecular programming biological chemistry rna biology vaccine development vaccine research genome structure crisscross polymerization nmr structure determination multilayer dna origami multi-micron crisscross structures dna-origami slats nature method coordination chemistry super-resolution imaging pharmaceutical nanotechnology nanoarchitectonics molecular regulation nanorobotics nucleic acid amplification vaccine efficacy programmable dna origami dna slats robust nucleation control single-stranded dna biomedical imaging computational imaging fish biology redox biology genetic programming bone research vascular biology molecular physiology advanced imaging 3d imaging foldable structure protective coatings sequence alignment cytogenetics genome analysis chromosome biology scanning probe microscopy genome instability structural dna nanotechnology dna-origami shapes dna bricks

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Computational Framework for Designing Micron-Scale Crisscross Dna Megastructures. bioRxiv (Cold Spring Harbor Laboratory) (2026)

biomolecular structurebiophysicsstructural biologycomputational frameworknucleic acidsmolecular biologystructural molecular biologydna nanotechnology

Enhanced Lung Delivery of an Immunostimulatory Duplex Rna Augments the Antitumor Activity by Reshaping Systemic Cytokine Pharmacodynamics. bioRxiv (Cold Spring Harbor Laboratory) (2026)

immunotherapyimmunomodulationimmunologymedicinal research

Enhanced Stability and Sustained Delivery of Structurally Dense Dna Nanostructures via a Biodegradable Hydrogel Platform. Nanoscale Horizons (2026)

nanoparticle researchdna computingbiodegradable hydrogel platformmolecular engineeringgene deliverycontrolled releasebiopolymer geldrug deliverybiomolecular engineeringbiomaterialsdense dnapolyelectrolyte gelbiopolymersbiomedical engineeringdna nanotechnologysustained deliverybiological engineering

Dna Nanostructures for Modular Growth Factor Delivery and Peripheral Nerve Repair. Nano Letters (2025)

nanoparticle researchgene deliverycontrolled releasedrug deliverybiomolecular engineeringperipheral nerve repairbiomaterialsnano-drug deliverybiomedical engineeringdna nanotechnologydna nanostructures

Megastructure Design and Image Dataset Accompanying the Preprint"a Computational Framework for Designing Micron-Scale Crisscross Dna Megastructures". Zenodo (CERN European Organization for Nuclear Research) (2025)

sequence assemblybioinformaticsbiomolecular structurebiophysicsstructural biologycomputational biologya computational frameworknucleic acidsmolecular biologystructural molecular biologygenome biologymegastructure designgenome structureimage dataset accompanying

Single-Molecule Mechanostructural Fingerprinting of Nucleic Acid Conformations. Nucleic Acids Research (2025)

biophysical chemistrynucleic acid chemistrysingle moleculesbiomolecular structurebiophysicsstructural biologymolecular structurenucleic acidsmolecular biologystructural molecular biologysingle molecule biophysicsconformational studiesmolecular biophysics

764 Dna Origami Vaccine (Dorivac) for Cancer Immunotherapy. Regular and Young Investigator Award Abstracts (2024)

Yang C ZengHawa DembeleOlivia YoungGiorgia IsinelliJu Hee RyuWilliam Shih

vaccine developmentcancer immunotherapyvaccinesdna origami vaccinetherapeutic vaccinesimmunotherapyimmunologyvaccine researchvaccination

Branching Crisscross Polymerization of Single-Stranded Dna Slats. Journal of the American Chemical Society (2024)

Jie DengDionis MinevAnastasia ErshovaWilliam M. Shih

materials sciencenanotechnologycrisscross polymerizationchemical engineeringsingle-stranded dna slatsmolecular engineeringbiomolecular engineeringpolymer science

Cargo Quantification of Functionalized Dna Origami for Therapeutic Application. Small Methods (2024)

Olivia J. YoungHawa DembeleAnjali RajwarIck Chan KwonJu Hee RyuWilliam M. ShihYang C. Zeng

cargo quantificationtherapeutic applicationfunctionalized dna origami

Dna Origami Colloidal Crystals: Opportunities and Challenges. Nano Letters (2024)

Jaewon LeeJangwon KimGregor PosnjakAnastasia ErshovaDaichi HayakawaWilliam M. ShihW. Benjamin RogersYonggang KeTim LiedlSeungwoo Lee

dna computingnanotechnologycrystal researchdna repaircrystal growthnanomaterialsthin filmscolloid chemistrynucleic acidsmolecular biologybiomolecular engineeringcrystal engineeringcolloidal nanocrystalscolloidal materialsdna replicationdispersion sciencedna nanotechnologybiological engineering

1
2
3
4
5
12
10 / page

William Shih

Professor of Biological Chemistry and Molecular Pharmacology

Harvard University

Affiliations

Harvard Medical School

Biological Chemistry and Molecular Pharmacology

William Shih is currently serving as a Biological Chemistry And Molecular Pharmacology Professor of Biological Chemistry and Molecular Pharmacology at Harvard University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

William Shih

Harvard University

Professor of Biological Chemistry and Molecular Pharmacology

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

A Computational Framework for Designing Micron-Scale Crisscross Dna Megastructures. bioRxiv (Cold Spring Harbor Laboratory) (2026)

biomolecular structurebiophysicsstructural biologycomputational frameworknucleic acidsmolecular biologystructural molecular biologydna nanotechnology

Enhanced Lung Delivery of an Immunostimulatory Duplex Rna Augments the Antitumor Activity by Reshaping Systemic Cytokine Pharmacodynamics. bioRxiv (Cold Spring Harbor Laboratory) (2026)

immunotherapyimmunomodulationimmunologymedicinal research

Enhanced Stability and Sustained Delivery of Structurally Dense Dna Nanostructures via a Biodegradable Hydrogel Platform. Nanoscale Horizons (2026)

Dna Nanostructures for Modular Growth Factor Delivery and Peripheral Nerve Repair. Nano Letters (2025)

Single-Molecule Mechanostructural Fingerprinting of Nucleic Acid Conformations. Nucleic Acids Research (2025)

764 Dna Origami Vaccine (Dorivac) for Cancer Immunotherapy. Regular and Young Investigator Award Abstracts (2024)

Yang C ZengHawa DembeleOlivia YoungGiorgia IsinelliJu Hee RyuWilliam Shih

vaccine developmentcancer immunotherapyvaccinesdna origami vaccinetherapeutic vaccinesimmunotherapyimmunologyvaccine researchvaccination

Branching Crisscross Polymerization of Single-Stranded Dna Slats. Journal of the American Chemical Society (2024)

Jie DengDionis MinevAnastasia ErshovaWilliam M. Shih

materials sciencenanotechnologycrisscross polymerizationchemical engineeringsingle-stranded dna slatsmolecular engineeringbiomolecular engineeringpolymer science

Cargo Quantification of Functionalized Dna Origami for Therapeutic Application. Small Methods (2024)

Olivia J. YoungHawa DembeleAnjali RajwarIck Chan KwonJu Hee RyuWilliam M. ShihYang C. Zeng

cargo quantificationtherapeutic applicationfunctionalized dna origami

Dna Origami Colloidal Crystals: Opportunities and Challenges. Nano Letters (2024)

Jaewon LeeJangwon KimGregor PosnjakAnastasia ErshovaDaichi HayakawaWilliam M. ShihW. Benjamin RogersYonggang KeTim LiedlSeungwoo Lee

1
2
3
4
5
12
10 / page

Similar Faculty Members

Peng Yin

Institution

Harvard University

biomolecular structure

novel imaging method

Anatoly B. Kolomeisky

Institution

Rice University

theoretical chemistry

theoretical biology

Markita Landry

Institution

University of California, Berkeley

nanotechnology

materials science

Chenxiang Lin

Institution

Yale University

biosensor

biotechnology advance

Norbert O. Reich

Institution

University of California, Santa Barbara

pharmaceutical nanotechnology

biotechnology advance

Kent Kirshenbaum

Institution

New York University

synthetic biology

biomimetic chemistry

Mark Bathe

Institution

Massachusetts Institute of Technology

synthetic biology

biotechnology advance

Richard Willson

Institution

University of Houston

biomolecular recognition

biomolecular analysis

Meni Wanunu

Institution

Northeastern University

nanoparticle research

nanoreactor

Cyrus Safinya

Institution

University of California, Santa Cruz

biological matter

complex fluids

Similar Faculty Members

Peng Yin

Institution

Harvard University

biomolecular structure

novel imaging method

Anatoly B. Kolomeisky

Institution

Rice University

theoretical chemistry

theoretical biology

Markita Landry

Institution

University of California, Berkeley

nanotechnology

materials science

Chenxiang Lin

Institution

Yale University

biosensor

biotechnology advance

Norbert O. Reich

Institution

University of California, Santa Barbara

pharmaceutical nanotechnology

biotechnology advance

Kent Kirshenbaum

Institution

New York University

synthetic biology

biomimetic chemistry

Mark Bathe

Institution

Massachusetts Institute of Technology

synthetic biology

biotechnology advance

Richard Willson

Institution

University of Houston

biomolecular recognition

biomolecular analysis

Meni Wanunu

Institution

Northeastern University

nanoparticle research

nanoreactor

Cyrus Safinya

Institution

University of California, Santa Cruz

biological matter

complex fluids