Faculty

Institution

Unit

Venue

Josh Wand

University Distinguished Professor and Head Biochemistry & Biophysics Professor Biochemistry & Biophysics Chemistry Molecular & Cellular Medicine

Texas A&M University

Affiliations

College of Agriculture and Life Sciences

Biochemistry and Biophysics

Josh Wand is currently serving as a Biochemistry And Biophysics University Distinguished Professor and Head Biochemistry & Biophysics Professor Biochemistry & Biophysics Chemistry Molecular & Cellular Medicine at Texas A&M University.

Honors

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Experiences

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Education

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Josh Wand

Texas A&M University

University Distinguished Professor and Head Biochemistry & Biophysics Professor Biochemistry & Biophysics Chemistry Molecular & Cellular Medicine

You can click a keyword to filter the displayed items

biophysics structural biology protein science biochemistry molecular biology protein structure nuclear magnetic resonance biomolecular engineering structural molecular biology protein nmr nuclear magnetic resonance spectroscopy biomolecular structure biophysical chemistry molecular biophysics protein chemistry protein folding membrane biology protein engineering molecular structure magnetic resonance virus research biological macromolecules biophysical review biophysical modeling encapsulated proteins peptides conformational entropy experimental biophysics peptide science protein structure prediction magnetic resonance spectroscopy nmr spectroscopy molecular recognition reverse micelles biomolecular analysis protein modeling single molecule biophysics low viscosity fluids entropy medical virology enzyme inhibition solid-state nmr spectroscopy antiviral drug development antiviral research biological chemistry clinical microbiology vaccine design protein assembly computational biophysics main chain solution structure nmr relaxation antiviral therapy protein phosphorylation proteinlipid interaction vaccine development vaccine research biophysical aspect hydrogen exchange side chain dynamics protein bioinformatics structural integrity protein function structure determination antiviral drugs molecular spectroscopy structure elucidation carbohydrate-protein interactions micelles peptide engineering cold denaturation two-dimensional proton solution nmr radical enzymes calmodulin-peptide complex dynamic activation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Harmonizing Peak Matching Between Multidimensional Nmr Spectra. bioRxiv (Cold Spring Harbor Laboratory) (2026)

physicssolid-state nmr spectroscopyspectroscopynuclear magnetic resonance spectroscopymagnetic resonancemagnetic resonance spectroscopynuclear magnetic resonance

Peptidomimetic α,β-Unsaturated Ethyl Esters Are Irreversible Inactivators of Human Cathepsin L and Are Potent Inhibitors of Sars-Cov-2 in Cellular Models of Covid-19. Journal of Medicinal Chemistry (2026)

medicinal chemistrypharmacologysars-cov-2pharmaceutical chemistryenzyme inhibitionbiochemistrymedicinal research

Ubiquitin Azapeptide Esters as Next-Generation Activity-Based Probes for Cysteine Enzymes in the Ubiquitin Signal Pathway. Journal of the American Chemical Society (2025)

Saibal ChandaSandeep AtlaXinlei ShengSatyanarayana NyalataYugendar R. AlugubelliDemonta D. ColemanWen JiangRosana LopesShaodong GuoA. Joshua WandYingming ZhaoWenshe Ray Liu

next-generation activity-based probesbiochemistryprotein scienceubiquitin azapeptide estersnanomedicineprotein engineeringfunctional modificationstructure-function enzyme kineticsbiomolecular engineeringubiquitin signal pathwaypeptide engineeringprotein assemblystructural molecular biologyenzymeschemical biologypeptide sciencecysteine enzymesprotein chemistrymolecular biologypeptidesbiological macromoleculestherapeutic targets

Conformational Entropy in Protein Stability, Molecular Recognition and Allosteric Regulation. Biophysical Journal (2024)

Josh WandAnthony C. BishopJose Alfredo CaroTaylor R. ColeSravya KotaruMauricio LasagnaRosana LopesGlorise Montalvo-TorresKelly RischWeimin Tan

conformational entropymolecular recognitionallosteric regulationbiophysicsprotein stabilitymolecular biophysics

Cooperative Substructure and Energetics of Allosteric Regulation of the Catalytic Core of the E3 Ubiquitin Ligase Parkin by Phosphorylated Ubiquitin. Biomolecules (2024)

Xiang YeSravya KotaruRosana LopesShannen CravensMauricio LasagnaA. Joshua Wand

biomolecular structureallosteric regulationprotein structurebiochemistrycatalytic coreprotein phosphorylationphosphorylated ubiquitinbiomolecules

How to Design a Protein That Can Be Switched on and Off. Nature (2024)

A. Joshua Wand

protein designsynthetic biologybiophysicsprotein engineeringprotein foldingprotein structureprotein assemblymolecular biologybiomolecular engineeringstructural molecular biologyprotein modelingprotein evolutionprotein synthesisprotein sciencebiomoleculesprotein chemistry

Deep Mining of the Protein Energy Landscape. Structural Dynamics (2023)

A. Joshua Wand

protein energy landscapedeep miningbioinformaticsbiophysicsstructural biologyprotein structureprotein modelingprotein science

Protective Efficacy of Novel Engineered Human Ace2-Fc Fusion Protein Against Pan-Sars-Cov-2 Infection in Vitro and in Vivo. Journal of Medicinal Chemistry (2023)

Bo YuAleksandra DrelichJason HsuVivian TatBi-Hung PengQisheng WeiJianming WangHong WangJohn WagesAndrew R. MendelsohnJames W. LarrickChien-Te Tseng

infection controlmedicineprotective efficacyclinical microbiologyprotein engineeringclinical pharmacologyantiviral therapybiological engineeringmedicinal chemistrypharmacologypharmacotherapyantiviral drug developmentsars-cov-2drug discoverytherapeutic efficacytranslational medicinemedicinal researchantiviral researchnovel therapies

Robust Automated Backbone Triple Resonance Nmr Assignments of Proteins Using Bayesian-Based Simulated Annealing. Nature Communications (2023)

Anthony C. BishopGlorisé Torres-MontalvoSravya KotaruKyle MimunA. Joshua Wand

protein nmrbiophysicsstructural biologysimulated annealingbayesian-based simulated annealingprotein structureprotein sciencenuclear magnetic resonance

A Fine Balance of Hydrophobic-Electrostatic Communication Pathways in a Ph-Switching Protein. Proceedings of the National Academy of Sciences (2022)

Duncan W. S. MacKenzieAnna SchaeferJulia StecknerChristopher A. LeoDalia NaserEfrosini ArtikisAron BroomTravis KoPurnank ShahMikaela Q. NeyElisa TranMartin T. J. SmithBrian FuglestadA. Joshua WandCharles L. BrooksElizabeth M. Meiering

membrane biologycommunicationbiophysicsamphiphilic systemneuroscienceph-switching proteinfine balanceprotein sciencehydrophobic-electrostatic communication pathways

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Josh Wand

University Distinguished Professor and Head Biochemistry & Biophysics Professor Biochemistry & Biophysics Chemistry Molecular & Cellular Medicine

Texas A&M University

Affiliations

College of Agriculture and Life Sciences

Biochemistry and Biophysics

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Josh Wand

Texas A&M University

University Distinguished Professor and Head Biochemistry & Biophysics Professor Biochemistry & Biophysics Chemistry Molecular & Cellular Medicine

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Harmonizing Peak Matching Between Multidimensional Nmr Spectra. bioRxiv (Cold Spring Harbor Laboratory) (2026)

physicssolid-state nmr spectroscopyspectroscopynuclear magnetic resonance spectroscopymagnetic resonancemagnetic resonance spectroscopynuclear magnetic resonance

medicinal chemistrypharmacologysars-cov-2pharmaceutical chemistryenzyme inhibitionbiochemistrymedicinal research

Ubiquitin Azapeptide Esters as Next-Generation Activity-Based Probes for Cysteine Enzymes in the Ubiquitin Signal Pathway. Journal of the American Chemical Society (2025)

Saibal ChandaSandeep AtlaXinlei ShengSatyanarayana NyalataYugendar R. AlugubelliDemonta D. ColemanWen JiangRosana LopesShaodong GuoA. Joshua WandYingming ZhaoWenshe Ray Liu

Conformational Entropy in Protein Stability, Molecular Recognition and Allosteric Regulation. Biophysical Journal (2024)

Josh WandAnthony C. BishopJose Alfredo CaroTaylor R. ColeSravya KotaruMauricio LasagnaRosana LopesGlorise Montalvo-TorresKelly RischWeimin Tan

conformational entropymolecular recognitionallosteric regulationbiophysicsprotein stabilitymolecular biophysics

Cooperative Substructure and Energetics of Allosteric Regulation of the Catalytic Core of the E3 Ubiquitin Ligase Parkin by Phosphorylated Ubiquitin. Biomolecules (2024)

Xiang YeSravya KotaruRosana LopesShannen CravensMauricio LasagnaA. Joshua Wand

biomolecular structureallosteric regulationprotein structurebiochemistrycatalytic coreprotein phosphorylationphosphorylated ubiquitinbiomolecules

How to Design a Protein That Can Be Switched on and Off. Nature (2024)

A. Joshua Wand

Deep Mining of the Protein Energy Landscape. Structural Dynamics (2023)

A. Joshua Wand

protein energy landscapedeep miningbioinformaticsbiophysicsstructural biologyprotein structureprotein modelingprotein science

Protective Efficacy of Novel Engineered Human Ace2-Fc Fusion Protein Against Pan-Sars-Cov-2 Infection in Vitro and in Vivo. Journal of Medicinal Chemistry (2023)

Bo YuAleksandra DrelichJason HsuVivian TatBi-Hung PengQisheng WeiJianming WangHong WangJohn WagesAndrew R. MendelsohnJames W. LarrickChien-Te Tseng

Robust Automated Backbone Triple Resonance Nmr Assignments of Proteins Using Bayesian-Based Simulated Annealing. Nature Communications (2023)

Anthony C. BishopGlorisé Torres-MontalvoSravya KotaruKyle MimunA. Joshua Wand

protein nmrbiophysicsstructural biologysimulated annealingbayesian-based simulated annealingprotein structureprotein sciencenuclear magnetic resonance

A Fine Balance of Hydrophobic-Electrostatic Communication Pathways in a Ph-Switching Protein. Proceedings of the National Academy of Sciences (2022)

membrane biologycommunicationbiophysicsamphiphilic systemneuroscienceph-switching proteinfine balanceprotein sciencehydrophobic-electrostatic communication pathways

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25
10 / page

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