Faculty

Institution

Unit

Venue

Cyrus Vaziri

Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Biochemistry and Biophysics

Pathology and Laboratory Medicine

the Graduate School

Cyrus Vaziri is currently serving as a Biochemistry And Biophysics Professor at University of North Carolina At Chapel Hill.

Honors

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Experiences

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Education

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Cyrus Vaziri

University of North Carolina at Chapel Hill

Professor

You can click a keyword to filter the displayed items

molecular biology genetics cell biology cancer research tumor biology cancer biology dna repair oncology pharmacology gene expression medicinal research cancer genetics molecular cancer oncogenes cell cycle cancer genomics molecular cell biology dna replication genome biology cell regulation cancer treatment biological chemistry cancer care cell signaling protein science cancer cells membrane biology enzyme inhibition nucleic acids tumor targeting trans-lesion synthesis leukemia mammalian biology genome instability cell death redox biology molecular regulation cellular biology gene regulation cancer management rna biology surgical oncology anti-cancer agents transcription regulation signaling pathways cancer growth mutagenesis gene function apoptosis tumor suppressors cell proliferation biological inorganic chemistry protein chemistry molecular substrates protein phosphorylation cytogenetics cutaneous biology fibroblast growth factors tissue development pancreatic cancer redox signaling replication forks dna polymerases bulky dna adducts mitogenic growth factors dna damage response atr inhibition premature chromatin condensation s-phase checkpoint-mediated arrest s-phase checkpoint microarray profiling experiments smoc-2 adenovirus sparc family retinoblastoma protein-mediated signals pcna monoubiquitination chromatin loading carcinogenesis plo biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract B035: Evidence for Cd73 Loss Promoting Cancer Cell Stemness via Metabolic Reprogramming in Endometrial Cancer. Clinical Cancer Research (2024)

Emily M. RabjohnsBlake R. RushingSayali JosephCyrus VaziriJessica L. Bowser

gynecologic oncologycancer caretumor biologycancer cell stemnesscell biologymedicinal researchdermatologycell metabolismoutcomes researchcancer researchendometrial cancercancer managementclinical researchcancer cellscancer treatmenthealth sciencesoncologycancer biology

Abstract Ia022: Harnessing the Unique Biology of Cd73 for Improving Endometrial Cancer Outcomes. Clinical Cancer Research (2024)

Jessica L. BowserHannah N. LeeRebecca H. HirschXingyuan ZhangRussell R. BroaddusKatherine C. KurnitSuzanne M. CrumleySunthoshini PremsankarEmily M. RabjohnsLilly F. ChiouCyrus Vaziri

gynecologic oncologyendometrial cancer outcomestumor biologycell biologycancer researchmolecular biologycancer treatmentunique biologymedicinal researchsystems biologycancer managementcancer carecancer biologygenome biologytumor targetingmolecular medicinemolecular cell biologyclinical researchcancer genomicsoncology

Abstract Pr004: Cd73 is a Novel Repressor of Mutant β-Catenin Oncogenic Activity in Endometrial Cancer. Clinical Cancer Research (2024)

Rebecca M. HirschXingyuan ZhangLilly F. ChiouSunthoshini PremsankarHannah N. LeeKatherine C. KurnitRussell R. BroaddusCyrus VaziriJessica L. Bowser

gynecologic oncologyendometrial cancerpharmacologytumor biologynovel repressorcancer immunotherapycancer researchtumor suppressorscancer treatmentoncogenesradiation oncologymedicinal researchclinical investigationoncogenic agentcancer carecancer biologygynecologyclinical researchcancer genomicsoncology

Author Correction: A Neomorphic Cancer Cell-Specific Role of Mage-A4 in Trans-Lesion Synthesis. Nature Communications (2024)

Yanzhe GaoElizabeth Mutter-RottmayerAlicia M GreenwaltDennis GoldfarbFeng YanYang YangRaquel C Martinez-ChacinKenneth H PearceSatoshi TateishiMichael B MajorCyrus Vaziri

trans-lesion synthesiscancer researchmolecular biologycancer biology

Cd73 Restrains Mutant β-Catenin Oncogenic Activity in Endometrial Carcinomas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Rebecca M. HirschSunthoshini PremsankarKatherine C. KurnitLilly F. ChiouEmily M. RabjohnsHannah N. LeeRussell R. BroaddusCyrus VaziriJessica L. Bowser

oncogenesgynecologic oncologyendometrial carcinomastumor biologyoncogenic agentmolecular biologyoncologycancer biology

Crystal Structure of Magea4 Mhd-Rad18 R6Bd Reveals a Flipped Binding Mode Compared to Alphafold2 Prediction. The EMBO Journal (2024)

Karly ForkerMatthew C FlemingKenneth H PearceCyrus VaziriAlbert A BowersPei Zhou

biophysicscrystal structuresprotein x-ray crystallographyflipped binding modebiomolecular structurecrystallographyx-ray crystallographymolecular biologyprotein structuremolecular structurestructural molecular biologystructural biology

Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Carly S. WilliamsXin LiHongjun JangJay Ramanlal AnandWon Young LimHyejin LeeJulie ParksXingyuan ZhangJialiu XieJinshi ZhaoDi WuAndrew J. ArmstrongJessica L. BowserLee ZouJiyong HongJason A. SomarelliCyrus VaziriPei Zhou

endocrine-related cancersreplication stress vulnerabilityandrogen receptorprostate cancermolecular biology

Mapk14/P38α Shapes the Molecular Landscape of Endometrial Cancer and Promotes Tumorigenic Characteristics. Cell Reports (2024)

Sayali JosephXingyuan ZhangGaith N DrobyDi WuVictoria Bae-JumpScott LyonsAngie MordantAllie MillsLaura HerringBlake RushingJessica L BowserCyrus Vaziri

tumor biologycancer biologycell biologymolecular landscapecancer researchendometrial cancermolecular biologytumorigenic characteristicsmammalian biologyoncologygenetics

Pcna-Binding Activity Separates Rnf168 Functions in Dna Replication and Dna Double-Stranded Break Signaling. Nucleic Acids Research (2024)

Yang YangDeepika JayaprakashSatpal S JhujhJohn J ReynoldsSteve ChenYanzhe GaoJay Ramanlal AnandElizabeth Mutter-RottmayerPablo ArielJing AnXing ChengKenneth H PearceSophie-Anne BlanchetNandana NandakumarPei ZhouAmélie Fradet-TurcotteGrant S StewartCyrus Vaziri

nucleic acidsdna replicationpcna-binding activitymolecular biologydna double-stranded break

Rev7-P53 Interaction Inhibits Atm-Mediated Dna Damage Signaling. Cell Cycle (2024)

Megan BillerSara KabirChkylle BoadoSarah NipperAlexandra SaffaAriella TalSydney AllenHiroyuki SasanumaDidier DréauCyrus VaziriJunya Tomida

oncogenescell cycleapoptosistumor biologycell signalingcell biologymolecular canceratm-mediated dna damagecancer geneticsmolecular biologygene expressiondna repairrna biologygenetics

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Cyrus Vaziri

Professor

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Biochemistry and Biophysics

Pathology and Laboratory Medicine

the Graduate School

Cyrus Vaziri is currently serving as a Biochemistry And Biophysics Professor at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Cyrus Vaziri

University of North Carolina at Chapel Hill

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract B035: Evidence for Cd73 Loss Promoting Cancer Cell Stemness via Metabolic Reprogramming in Endometrial Cancer. Clinical Cancer Research (2024)

Emily M. RabjohnsBlake R. RushingSayali JosephCyrus VaziriJessica L. Bowser

Abstract Ia022: Harnessing the Unique Biology of Cd73 for Improving Endometrial Cancer Outcomes. Clinical Cancer Research (2024)

Jessica L. BowserHannah N. LeeRebecca H. HirschXingyuan ZhangRussell R. BroaddusKatherine C. KurnitSuzanne M. CrumleySunthoshini PremsankarEmily M. RabjohnsLilly F. ChiouCyrus Vaziri

Abstract Pr004: Cd73 is a Novel Repressor of Mutant β-Catenin Oncogenic Activity in Endometrial Cancer. Clinical Cancer Research (2024)

Rebecca M. HirschXingyuan ZhangLilly F. ChiouSunthoshini PremsankarHannah N. LeeKatherine C. KurnitRussell R. BroaddusCyrus VaziriJessica L. Bowser

Author Correction: A Neomorphic Cancer Cell-Specific Role of Mage-A4 in Trans-Lesion Synthesis. Nature Communications (2024)

Yanzhe GaoElizabeth Mutter-RottmayerAlicia M GreenwaltDennis GoldfarbFeng YanYang YangRaquel C Martinez-ChacinKenneth H PearceSatoshi TateishiMichael B MajorCyrus Vaziri

trans-lesion synthesiscancer researchmolecular biologycancer biology

Cd73 Restrains Mutant β-Catenin Oncogenic Activity in Endometrial Carcinomas. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Rebecca M. HirschSunthoshini PremsankarKatherine C. KurnitLilly F. ChiouEmily M. RabjohnsHannah N. LeeRussell R. BroaddusCyrus VaziriJessica L. Bowser

oncogenesgynecologic oncologyendometrial carcinomastumor biologyoncogenic agentmolecular biologyoncologycancer biology

Crystal Structure of Magea4 Mhd-Rad18 R6Bd Reveals a Flipped Binding Mode Compared to Alphafold2 Prediction. The EMBO Journal (2024)

Karly ForkerMatthew C FlemingKenneth H PearceCyrus VaziriAlbert A BowersPei Zhou

Inhibition of Androgen Receptor Exposes Replication Stress Vulnerability in Prostate Cancer. bioRxiv (Cold Spring Harbor Laboratory) (2024)

endocrine-related cancersreplication stress vulnerabilityandrogen receptorprostate cancermolecular biology

Mapk14/P38α Shapes the Molecular Landscape of Endometrial Cancer and Promotes Tumorigenic Characteristics. Cell Reports (2024)

Sayali JosephXingyuan ZhangGaith N DrobyDi WuVictoria Bae-JumpScott LyonsAngie MordantAllie MillsLaura HerringBlake RushingJessica L BowserCyrus Vaziri

tumor biologycancer biologycell biologymolecular landscapecancer researchendometrial cancermolecular biologytumorigenic characteristicsmammalian biologyoncologygenetics

Pcna-Binding Activity Separates Rnf168 Functions in Dna Replication and Dna Double-Stranded Break Signaling. Nucleic Acids Research (2024)

nucleic acidsdna replicationpcna-binding activitymolecular biologydna double-stranded break

Rev7-P53 Interaction Inhibits Atm-Mediated Dna Damage Signaling. Cell Cycle (2024)

Megan BillerSara KabirChkylle BoadoSarah NipperAlexandra SaffaAriella TalSydney AllenHiroyuki SasanumaDidier DréauCyrus VaziriJunya Tomida

oncogenescell cycleapoptosistumor biologycell signalingcell biologymolecular canceratm-mediated dna damagecancer geneticsmolecular biologygene expressiondna repairrna biologygenetics

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