Faculty

Institution

Unit

Venue

Vaughn Jackson

Emeritus Professor

Medical College of Wisconsin

Affiliations

Biochemistry

Vaughn Jackson is currently serving as a Biochemistry Emeritus Professor at Medical College of Wisconsin.

Honors

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Experiences

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Education

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Vaughn Jackson

Medical College of Wisconsin

Emeritus Professor

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biochemistry molecular biology chromatin gene expression chromatin remodeling transcription (biology) nuclear organization cell biology nucleic acids systems biology epigenetics dna replication protein science molecular cell biology structural molecular biology biological chemistry chromosomal rearrangements transcription regulation rna biology transcription factors membrane biology tumor biology epigenomics chromosome biology protein phosphorylation protein synthesis histone release vascular biology redox biology stem cell research biological macromolecules biomolecular structure nucleation cell cycle protein assembly bone research insect molecular biology molecular structure molecular cancer histopathology cancer cells cell migration large scale structure novel interface in-situ conversion surface reactivity selective separation fragmentation effect surface modification cross-link cell culture tissue culture cell proliferation reproductive hormones ovarian hormones endocrine research hormonal receptor female reproductive system depositional process protein chemistry molecular evidence histone-dna interaction nucleosome dissolution reversible cross-linking agent histone organization nucleosome family selective deposition old dna replicative chromatin hybrid nucleosomes daughter dna strands formaldehyde cross-linking nucleosomal dynamics lysine-rich histones histone segregation histone synthesis genome biology structural biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Multivalent Nucleosome Scaffolding by Bromodomain and Extraterminal Domain Tandem Bromodomains. Journal of Biological Chemistry (2025)

Michael D OlpKarina L BurschSarah L Wynia-SmithRaymundo NuñezChristopher J GoetzVaughn JacksonBrian C Smith

molecular and cellular biologymatrix biologybiomoleculessupramolecular assembliessynthetic biologystructural molecular biologyprotein synthesismolecular biologymultivalent nucleosome scaffoldingprotein assemblydna repairbiochemistrydna replicationbiological chemistrymulti-protein assemblychromatin remodelingmolecular cell biologychromatinbiomolecular engineering

Nucleosome Scaffolding by Brd4 Tandem Bromodomains in Acetylation-Dependent Chromatin Compartmentalization. bioRxiv (Cold Spring Harbor Laboratory) (2019)

Michael D. OlpVaughn JacksonBrian C. Smith

chromatin remodelingacetylation-dependent chromatin compartmentalizationchromosome biologybiochemistrymolecular biologychromatinnucleosome scaffoldingbiomolecular engineering

A Mutational Mimic Analysis of Histone H3 Post-Translational Modifications: Specific Sites Influence the Conformational State of H3/H4, Causing Either Positive or Negative Supercoiling of Dna. Biochemistry (2012)

Rachel H. WhiteMelissa KeberleinVaughn Jackson

conformational statemutational mimic analysisepigeneticsbiochemistrymolecular biologyspecific sitesgenetics

The Nucleosome Family: Dynamic and Growing. Structure (2009)

Jordanka ZlatanovaThomas C. BishopJean-Marc VictorVaughn JacksonKen van Holde

molecular and cellular biologychromatin remodelingbiomolecular structurechromosome biologymolecular structurechromosomal rearrangementsnucleationbiologynuclear organizationnucleosome familymolecular biologychromatinsystems biologygene expressionstructural molecular biologystructural biology

Acetylation of H4 Suppresses the Repressive Effects of the N-Termini of Histones H3/H4 and Facilitates the Formation of Positively Coiled Dna. Biochemistry (2008)

Sharon PetersonVaughn Jackson

chromatin remodelingnucleic acidsbiochemistrydna replicationnuclear organizationmolecular biologychromatinrepressive effectsgene expressiondna repair

Nap1 Catalyzes the Formation of Either Positive or Negative Supercoils on Dna on Basis of the Dimer−Tetramer Equilibrium of Histones H3/H4. Biochemistry (2007)

Sharon PetersonRachel DanowitAnn WunschVaughn Jackson

dimer-tetramer equilibriumbiochemistrynuclear organizationmolecular biologychromatinnegative supercoils

Fpr4 Modulates the Structure of Core Histones. The FASEB Journal (2006)

Haijie XiaoVaughn JacksonMing Lei

chromatin remodelingcore histonesprotein sciencebiomolecular structurecell biologybiochemistrymolecular biologychromatinprotein structuregene expressionstructural biology

The Fk506‐Binding Protein, Fpr4, is an Acidic Histone Chaperone. FEBS Letters (2006)

Haijie XiaoVaughn JacksonMing Lei

biological macromoleculeschromatin remodelingprotein phosphorylationprotein scienceprotein chemistrycell biologymolecular evidencebiochemistrymolecular cell biologytranscription (biology)molecular biologychromatinprotein structureacidic histone chaperonegene expressionstructural molecular biologystructural biology

Urea-Nuclease Treatment of Concentrated Retrovirions Preserves Viral Rna and Removes Polymerase Chain Reaction-Amplifiable Cellular Rna and Dna. Journal of Virological Methods (2006)

Hai-Yuan SunMark T. McNallyVaughn E. JacksonSidney E. Grossberg

viral rnavirologyurea-nuclease treatmentconcentrated retrovirionsgenetics

Histone Release During Transcription: Acetylation Stabilizes the Interaction of the H2A−H2B Dimer With the H3−H4 Tetramer in Nucleosomes That Are on Highly Positively Coiled Dna. Biochemistry (2005)

Ann WunschVaughn Jackson

gene expressiontranscription (biology)histone releasebiochemistry

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Vaughn Jackson

Emeritus Professor

Medical College of Wisconsin

Affiliations

Biochemistry

Vaughn Jackson is currently serving as a Biochemistry Emeritus Professor at Medical College of Wisconsin.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Vaughn Jackson

Medical College of Wisconsin

Emeritus Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Multivalent Nucleosome Scaffolding by Bromodomain and Extraterminal Domain Tandem Bromodomains. Journal of Biological Chemistry (2025)

Michael D OlpKarina L BurschSarah L Wynia-SmithRaymundo NuñezChristopher J GoetzVaughn JacksonBrian C Smith

Nucleosome Scaffolding by Brd4 Tandem Bromodomains in Acetylation-Dependent Chromatin Compartmentalization. bioRxiv (Cold Spring Harbor Laboratory) (2019)

Michael D. OlpVaughn JacksonBrian C. Smith

chromatin remodelingacetylation-dependent chromatin compartmentalizationchromosome biologybiochemistrymolecular biologychromatinnucleosome scaffoldingbiomolecular engineering

Rachel H. WhiteMelissa KeberleinVaughn Jackson

conformational statemutational mimic analysisepigeneticsbiochemistrymolecular biologyspecific sitesgenetics

The Nucleosome Family: Dynamic and Growing. Structure (2009)

Jordanka ZlatanovaThomas C. BishopJean-Marc VictorVaughn JacksonKen van Holde

Acetylation of H4 Suppresses the Repressive Effects of the N-Termini of Histones H3/H4 and Facilitates the Formation of Positively Coiled Dna. Biochemistry (2008)

Sharon PetersonVaughn Jackson

chromatin remodelingnucleic acidsbiochemistrydna replicationnuclear organizationmolecular biologychromatinrepressive effectsgene expressiondna repair

Nap1 Catalyzes the Formation of Either Positive or Negative Supercoils on Dna on Basis of the Dimer−Tetramer Equilibrium of Histones H3/H4. Biochemistry (2007)

Sharon PetersonRachel DanowitAnn WunschVaughn Jackson

dimer-tetramer equilibriumbiochemistrynuclear organizationmolecular biologychromatinnegative supercoils

Fpr4 Modulates the Structure of Core Histones. The FASEB Journal (2006)

Haijie XiaoVaughn JacksonMing Lei

chromatin remodelingcore histonesprotein sciencebiomolecular structurecell biologybiochemistrymolecular biologychromatinprotein structuregene expressionstructural biology

The Fk506‐Binding Protein, Fpr4, is an Acidic Histone Chaperone. FEBS Letters (2006)

Haijie XiaoVaughn JacksonMing Lei

Urea-Nuclease Treatment of Concentrated Retrovirions Preserves Viral Rna and Removes Polymerase Chain Reaction-Amplifiable Cellular Rna and Dna. Journal of Virological Methods (2006)

Hai-Yuan SunMark T. McNallyVaughn E. JacksonSidney E. Grossberg

viral rnavirologyurea-nuclease treatmentconcentrated retrovirionsgenetics

Ann WunschVaughn Jackson

gene expressiontranscription (biology)histone releasebiochemistry

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Similar Faculty Members

Alan Weiner

Institution

University of Washington

genome instability

chromatin remodeling

Mark Parthun

Institution

Ohio State University

pharmacological research

chromatin remodeling

Bruce Alberts

Institution

University of California, San Francisco

carcinogenesis

cancer cell

Simone Sidoli

Institution

Albert Einstein College of Medicine

protein mass spectrometry

proteome research

Jikui Song

Institution

University of California, Riverside

host-pathogen interaction

epigenetic regulation

Karolin Luger

Institution

Colorado State University

molecular biology

structural biology

Johannes Walter

Institution

Harvard University

dna helicase

molecular biology

Zhiguo Zhang

Institution

Columbia University

epigenetic change

epigenomics

Danesh Moazed

Institution

Harvard University

chromatin remodeling

gene expression

Evgeny A. Nudler, PhD

Institution

New York University

synthetic biology

mutagenesis (molecular biology technique)