Faculty

Institution

Unit

Venue

Mark Parthun

Professor and Chair

Ohio State University

Affiliations

College of Medicine

Biological Chemistry and Pharmacology

Mark Parthun is currently serving as a Biological Chemistry And Pharmacology Professor and Chair at Ohio State University.

Honors

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Experiences

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Education

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Mark Parthun

Ohio State University

Professor and Chair

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molecular biology chromatin cell biology chromatin remodeling biochemistry protein science gene expression molecular cell biology molecular and cellular biology mass spectrometry nucleic acids systems biology epigenetics cancer research enzyme inhibition proteomics cell signaling epigenomics chromosome biology epigenetic changes nuclear organization proteome research leukemia structural molecular biology protein mass spectrometry chromosomal rearrangements cancer biology peptides medicinal research molecular regulation yeast apoptosis histone deacetylase genome biology oncogenes biological chemistry rna biology gene function cellular biology gene regulation gene structure protein chemistry histone post-translational modifications histone acetylation chronic lymphocytic leukemia molecular metabolism molecular diagnostics peptide science stem cell research hematological malignancies chromatographic analysis lymphoid neoplasia liquid chromatography novel therapies cancer treatment chromatin structure telomeric silencing amino acids stable isotope reference frame key site primary investigation dna analysis host factors cell regulation hemostasis myeloid neoplasia molecular complexes histone metabolism peptide mass fingerprinting current perspectives cellular roles histone acetyltransferase double-strand break repair c-flip protein dna methyltransferase histone chaperones pharmacology chemical biology pharmacological research

Notable Scholarly Works

Notable Federal Grants

Collaborators

Distinct Classes of Lamin-Associated Domains Are Defined by Di7Erential Patterns of Repressive Histone Methylation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Caden J. MartinPrabakaran NagarajanElizabeth A. OserLiudmila V. PopovaMark R. Parthun

chromatin remodelingprotein scienceepigenetic changesepigeneticsbiochemistrystructural bioinformaticsrepressive histone methylationepigenomicsdistinct classesmolecular biologychromatinprotein structuresystems biologygene expressionlamin-associated domainsstructural biology

Established and Emerging Roles of Dead /H‐Box Helicases in Regulating Infection and Immunity. Immunological Reviews (2024)

Michael ParthunMatthew E. LongEmily A. Hemann

inflammationinfectious diseasesimmunopathologyclinical immunologyimmunologyimmune responsesimmunity (medicine)molecular biologyvirus researchadaptive immune systemautoimmunityimmunoeditinginnate immune systemmicrobial pathogenesis

Dynamic Reassociation of the Nuclear Lamina With Newly Replicated Dna. Research Square (Research Square) (2023)

Callie M. LovejoyPrabakaran NagarajanMark R. Parthun

chromatin remodelingnucleic acidsbiochemistrychromosomal rearrangementsdna replicationnuclear organizationmolecular biologynuclear laminadna repairgenetics

Epigenetic Regulation of Nuclear Lamina-Associated Heterochromatin by Hat1 and the Acetylation of Newly Synthesized Histones. Nucleic Acids Research (2021)

Liudmila V PopovaPrabakaran NagarajanCallie M LovejoyBenjamin D SunkelMiranda L GardnerMeng WangMichael A FreitasBenjamin Z StantonMark R Parthun

epigenetic regulationchromatin remodelingnucleic acidsepigeneticsmolecular biologychromatinnuclear lamina-associated heterochromatin

Histone Lysine Methacrylation is a Dynamic Post-Translational Modification Regulated by Hat1 and Sirt2. Cell Discovery (2021)

Kyle DelaneyMinjia TanZhesi ZhuJinjun GaoLunzhi DaiSunjoo KimJun DingMaomao HeLevon HalabelianLu YangPrabakaran NagarajanMark Robert ParthunSangkyu LeeSaadi KhochbinYujun George ZhengYingming Zhao

protein sciencedynamic post-translational modificationcell signalingcell biologycellular physiologycellular biologymolecular biologypharmacologymolecular regulationhistone lysine methacrylation

Hat1-Dependent Lysine Acetylation Targets Diverse Cellular Functions. Journal of Proteome Research (2020)

Paula A. Agudelo GarciaPrabakaran NagarajanMark R. Parthun

molecular and cellular biologyproteomicsenzymesmolecular metabolismprotein scienceprotein chemistrycell signalingprotein functionbiological functionbiochemistrymolecular cell biologycellular functionsmolecular biologysystems biologygene expressionenzyme inhibitionmolecular regulationproteome research

Histone Acetyltransferase 1 is Required for Dna Replication Fork Function and Stability. Journal of Biological Chemistry (2020)

Paula A. Agudelo GarciaCallie M. LovejoyPrabakaran NagarajanDongju ParkLiudmila V. PopovaMichael A. FreitasMark R. Parthun

biochemistrydna replicationbiologymolecular biologybiological chemistry

The Flip Side of Sirtuins: The Emerging Roles of Protein Acetyltransferases in Aging. Aging (2020)

Prabakaran NagarajanMark R. Parthun

protein acetyltransferasesaging cellaging processbiochemistry

Early‐Onset Aging and Mitochondrial Defects Associated With Loss of Histone Acetyltransferase 1 (Hat1). Aging Cell (2019)

Prabakaran NagarajanPaula A. Agudelo GarciaChitra C. IyerLiudmila V. PopovaWilliam D. ArnoldMark R. Parthun

biogerontologycell biologyageingearly-onset aginggeriatricsmitochondrial defects

Isolation of Proteins on Nascent Chromatin and Characterization by Quantitative Mass Spectrometry. Methods in molecular biology (2019)

Paula A. Agudelo GarciaMiranda GardnerMichael A. FreitasMark R. Parthun

molecular biological methodmolecular biologychromatinnascent chromatinquantitative mass spectrometry

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Mark Parthun

Professor and Chair

Ohio State University

Affiliations

College of Medicine

Biological Chemistry and Pharmacology

Mark Parthun is currently serving as a Biological Chemistry And Pharmacology Professor and Chair at Ohio State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mark Parthun

Ohio State University

Professor and Chair

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Distinct Classes of Lamin-Associated Domains Are Defined by Di7Erential Patterns of Repressive Histone Methylation. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Caden J. MartinPrabakaran NagarajanElizabeth A. OserLiudmila V. PopovaMark R. Parthun

Established and Emerging Roles of Dead /H‐Box Helicases in Regulating Infection and Immunity. Immunological Reviews (2024)

Michael ParthunMatthew E. LongEmily A. Hemann

Dynamic Reassociation of the Nuclear Lamina With Newly Replicated Dna. Research Square (Research Square) (2023)

Callie M. LovejoyPrabakaran NagarajanMark R. Parthun

chromatin remodelingnucleic acidsbiochemistrychromosomal rearrangementsdna replicationnuclear organizationmolecular biologynuclear laminadna repairgenetics

Epigenetic Regulation of Nuclear Lamina-Associated Heterochromatin by Hat1 and the Acetylation of Newly Synthesized Histones. Nucleic Acids Research (2021)

Liudmila V PopovaPrabakaran NagarajanCallie M LovejoyBenjamin D SunkelMiranda L GardnerMeng WangMichael A FreitasBenjamin Z StantonMark R Parthun

epigenetic regulationchromatin remodelingnucleic acidsepigeneticsmolecular biologychromatinnuclear lamina-associated heterochromatin

Histone Lysine Methacrylation is a Dynamic Post-Translational Modification Regulated by Hat1 and Sirt2. Cell Discovery (2021)

Kyle DelaneyMinjia TanZhesi ZhuJinjun GaoLunzhi DaiSunjoo KimJun DingMaomao HeLevon HalabelianLu YangPrabakaran NagarajanMark Robert ParthunSangkyu LeeSaadi KhochbinYujun George ZhengYingming Zhao

protein sciencedynamic post-translational modificationcell signalingcell biologycellular physiologycellular biologymolecular biologypharmacologymolecular regulationhistone lysine methacrylation

Hat1-Dependent Lysine Acetylation Targets Diverse Cellular Functions. Journal of Proteome Research (2020)

Paula A. Agudelo GarciaPrabakaran NagarajanMark R. Parthun

Histone Acetyltransferase 1 is Required for Dna Replication Fork Function and Stability. Journal of Biological Chemistry (2020)

Paula A. Agudelo GarciaCallie M. LovejoyPrabakaran NagarajanDongju ParkLiudmila V. PopovaMichael A. FreitasMark R. Parthun

biochemistrydna replicationbiologymolecular biologybiological chemistry

The Flip Side of Sirtuins: The Emerging Roles of Protein Acetyltransferases in Aging. Aging (2020)

Prabakaran NagarajanMark R. Parthun

protein acetyltransferasesaging cellaging processbiochemistry

Early‐Onset Aging and Mitochondrial Defects Associated With Loss of Histone Acetyltransferase 1 (Hat1). Aging Cell (2019)

Prabakaran NagarajanPaula A. Agudelo GarciaChitra C. IyerLiudmila V. PopovaWilliam D. ArnoldMark R. Parthun

biogerontologycell biologyageingearly-onset aginggeriatricsmitochondrial defects

Isolation of Proteins on Nascent Chromatin and Characterization by Quantitative Mass Spectrometry. Methods in molecular biology (2019)

Paula A. Agudelo GarciaMiranda GardnerMichael A. FreitasMark R. Parthun

molecular biological methodmolecular biologychromatinnascent chromatinquantitative mass spectrometry

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Similar Faculty Members

Brian D. Strahl

Institution

University of North Carolina at Chapel Hill

chromatin remodeling

yeast

James Wohlschlegel

Institution

University of California, Los Angeles

molecular informatics

bioinformatics

Philip A. Cole

Institution

Johns Hopkins University

molecular biology

biochemistry

Michele Pagano, MD

Institution

New York University

cell cycle

cell cycle control

Wei Li

Institution

University of California, Irvine

biomedical informatics

computational biology

Jonathan D Licht

Institution

University of Florida

oncology

pathology

Michael R. Lieber, MD, PhD

Institution

University of Southern California

cancer letter

genome instability

Kevin Struhl

Institution

Harvard University

transcription (biology)

oncogene

Neil Osheroff

Institution

Vanderbilt University

dna sequencing

molecular biology

Anthony E. Pegg

Institution

Pennsylvania State University

cancer letter

toxicological mechanism