Faculty

Institution

Unit

Venue

Thomas A. Cooper, M.D.

Professor

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

Thomas A. Cooper, M.d. is currently serving as a Baylor College Of Medicine Research Professor at Baylor College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Thomas A. Cooper, M.D.

Baylor College of Medicine

Professor

You can click a keyword to filter the displayed items

molecular biology gene expression genetics molecular cell biology splicing variant transcription (biology) cell biology molecular and cellular biology rna biology rna processing systems biology myotonic dystrophy molecular physiology nucleic acids transcription regulation molecular genetics protein science non-coding rna membrane biology human genetics cardiovascular research alternative splicing genome biology skeletal muscle muscle function muscular dystrophies gene regulation vascular biology cellular physiology structural molecular biology molecular neurodegeneration stem cell research genetic disorders gene function pathogenesis molecular regulation cardiac muscle cardiac pathologies cardiomyopathy biological chemistry mammalian biology cellular biology developmental cell protein expression gene editing molecular science medical genetics long non-coding rna small rna human disease rna-binding proteins molecular diagnostics transcriptomics technology developmental genetics degenerative disease biomolecular interactions genome instability pre-mrna splicing heart development skeletal muscle development mouse model mbnl proteins host factors inhibitory activity insulin signaling clinical pathology molecular pathology cell regulation t-regulatory cell splice-site selection antagonistic regulation toxic rna rna toxicity upstream intron decoding machinery splicing code developmental biology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mbnl Overexpression Rescues Cardiac Phenotypes in a Myotonic Dystrophy Type 1 Heart Mouse Model. Journal of Clinical Investigation (2025)

Rong-Chi HuYi ZhangLarissa NitschkeSara J. JohnsonAyrea E. HurleyWilliam R. LagorZheng XiaThomas A. Cooper

cardiovascular researchheart mouse modelclinical investigationclinical researchsystems biologycardiac pathologies

Alternatively Spliced Map4 Isoforms Have Key Roles in Maintaining Microtubule Organization and Skeletal Muscle Function. iScience (2024)

Lathan LucasLarissa NitschkeBrandon NguyenJames A LoehrGeorge G RodneyThomas A Cooper

microtubule organizationmolecular and cellular biologymuscle functioncell biologyskeletal muscle functionmolecular biology

Combinatorial Effects of Ion Channel Mis-Splicing as a Cause of Myopathy in Myotonic Dystrophy. Journal of Clinical Investigation (2024)

Larissa NitschkeThomas A. Cooper

cardiovascular diseaseliver physiologyion channel mis-splicingimmunologymechanobiologyelectrolyte disordersmuscular dystrophiesvascular biologyphysiologymyotonic dystrophycardiomyopathypath dependencesomatic dysfunctionclinical investigationneuromusculoskeletal disordersurologymusculoskeletal disordersstrokecardiovascular researchspinal cord injurycombinatorial effects

Rescue of Scn5A Mis-Splicing Does Not Improve the Structural and Functional Heart Defects of a Dm1 Heart Mouse Model. Human Molecular Genetics (2024)

Larissa NitschkeRong-Chi HuAndrew N MillerThomas A Cooper

human geneticsmolecular geneticsgenetic disordersgenetics

Small Molecule Screening Identifies Hsp90 as a Modifier of Rna Foci in Myotonic Dystrophy Type 1. Molecular and Cellular Biology (2024)

Sara J. JohnsonHannah L. JohnsonReid T. PowellClifford StephanFabio StossiThomas A. Cooper

molecular and cellular biologyrna focitranscription factorsbiologymolecular cell biologygene functiontranscription (biology)molecular biologysystems biologygene expression

Alternative Splicing Mediates the Compensatory Upregulation of Mbnl2 Upon Mbnl1 Loss-Of-Function. Nucleic Acids Research (2023)

Larissa NitschkeRong-Chi HuAndrew N MillerLathan LucasThomas A Cooper

compensatory upregulationgenome instabilitynucleic acidsalternative splicinggenome biologyneurosciencegene regulationtranscription regulationmolecular biologygene expressiongenetics

Clinical and Molecular Insights Into Gastrointestinal Dysfunction in Myotonic Dystrophy Types 1 & 2. nt J Mol Sci (2023)

pathologyphysiologygastroenterologydigestive diseasesfunctional gastrointestinal disordersgastrointestinal dysfunctionmolecular gastroenterologymuscular dystrophiesmolecular insights

Insights Into Cell-Specific Functions of Microtubules in Skeletal Muscle Development and Homeostasis. International Journal of Molecular Sciences (2023)

Lathan LucasThomas A. Cooper

muscle functioncell biologymolecular sciencedevelopmental biologyskeletal muscle developmentcell-specific functionsmolecular biology

The Role of Limch1 Alternative Splicing in Skeletal Muscle Function. Life Science Alliance (2023)

Matthew S PennaRong-Chi HuGeorge G RodneyThomas A Cooper

muscle functionskeletal muscle functionsplicing variantmolecular biologyskeletal muscle

The Role of Limch1 Alternative Splicing in Skeletal Muscle Function. Life Sci Alliance. (2023)

molecular and cellular biologylimch1 alternative splicingphysiologyrna processingmuscle functioncellular physiologysplicing variantmolecular physiologymolecular cell biologytranscription (biology)skeletal musclegene expressiongenetics

1
2
3
4
5
15
10 / page

Thomas A. Cooper, M.D.

Professor

Baylor College of Medicine

Affiliations

Baylor College of Medicine Research

Thomas A. Cooper, M.d. is currently serving as a Baylor College Of Medicine Research Professor at Baylor College of Medicine.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Thomas A. Cooper, M.D.

Baylor College of Medicine

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Mbnl Overexpression Rescues Cardiac Phenotypes in a Myotonic Dystrophy Type 1 Heart Mouse Model. Journal of Clinical Investigation (2025)

Rong-Chi HuYi ZhangLarissa NitschkeSara J. JohnsonAyrea E. HurleyWilliam R. LagorZheng XiaThomas A. Cooper

cardiovascular researchheart mouse modelclinical investigationclinical researchsystems biologycardiac pathologies

Alternatively Spliced Map4 Isoforms Have Key Roles in Maintaining Microtubule Organization and Skeletal Muscle Function. iScience (2024)

Lathan LucasLarissa NitschkeBrandon NguyenJames A LoehrGeorge G RodneyThomas A Cooper

microtubule organizationmolecular and cellular biologymuscle functioncell biologyskeletal muscle functionmolecular biology

Combinatorial Effects of Ion Channel Mis-Splicing as a Cause of Myopathy in Myotonic Dystrophy. Journal of Clinical Investigation (2024)

Larissa NitschkeThomas A. Cooper

Rescue of Scn5A Mis-Splicing Does Not Improve the Structural and Functional Heart Defects of a Dm1 Heart Mouse Model. Human Molecular Genetics (2024)

Larissa NitschkeRong-Chi HuAndrew N MillerThomas A Cooper

human geneticsmolecular geneticsgenetic disordersgenetics

Small Molecule Screening Identifies Hsp90 as a Modifier of Rna Foci in Myotonic Dystrophy Type 1. Molecular and Cellular Biology (2024)

Sara J. JohnsonHannah L. JohnsonReid T. PowellClifford StephanFabio StossiThomas A. Cooper

molecular and cellular biologyrna focitranscription factorsbiologymolecular cell biologygene functiontranscription (biology)molecular biologysystems biologygene expression

Alternative Splicing Mediates the Compensatory Upregulation of Mbnl2 Upon Mbnl1 Loss-Of-Function. Nucleic Acids Research (2023)

Larissa NitschkeRong-Chi HuAndrew N MillerLathan LucasThomas A Cooper

compensatory upregulationgenome instabilitynucleic acidsalternative splicinggenome biologyneurosciencegene regulationtranscription regulationmolecular biologygene expressiongenetics

Clinical and Molecular Insights Into Gastrointestinal Dysfunction in Myotonic Dystrophy Types 1 & 2. nt J Mol Sci (2023)

pathologyphysiologygastroenterologydigestive diseasesfunctional gastrointestinal disordersgastrointestinal dysfunctionmolecular gastroenterologymuscular dystrophiesmolecular insights

Insights Into Cell-Specific Functions of Microtubules in Skeletal Muscle Development and Homeostasis. International Journal of Molecular Sciences (2023)

Lathan LucasThomas A. Cooper

muscle functioncell biologymolecular sciencedevelopmental biologyskeletal muscle developmentcell-specific functionsmolecular biology

The Role of Limch1 Alternative Splicing in Skeletal Muscle Function. Life Science Alliance (2023)

Matthew S PennaRong-Chi HuGeorge G RodneyThomas A Cooper

muscle functionskeletal muscle functionsplicing variantmolecular biologyskeletal muscle

The Role of Limch1 Alternative Splicing in Skeletal Muscle Function. Life Sci Alliance. (2023)

1
2
3
4
5
15
10 / page

Similar Faculty Members

James F Martin, M.D., Ph.D.

Institution

Baylor College of Medicine

transcriptome

developmental biology

Francesco J. DeMayo

Institution

Baylor College of Medicine

transcriptome

pulmonary biology

Ju Chen

Institution

University of California, San Diego

naxos disease

pathology

Hugo J Bellen

Institution

Baylor College of Medicine

neurogenetics

neurodevelopmental disorder

Clifford Steer

Institution

University of Minnesota

gene editing

stem cell

Huda Yahya Zoghbi

Institution

Baylor College of Medicine

degenerative pathology

neurodevelopmental disorder

Andrea Ballabio, M.D

Institution

Baylor College of Medicine

lysosomal storage disorders

disease mechanism

Martin M. Matzuk, M.D., Ph.D.

Institution

Baylor College of Medicine

gynecology

developmental biology

Jonathan D. Wren, Ph.D.

Institution

University of Oklahoma

pediatrics

developmental behavioral pediatrics

Mario Medvedovic

Institution

University of Cincinnati

omics datasets

epigenetics

Similar Faculty Members

James F Martin, M.D., Ph.D.

Institution

Baylor College of Medicine

transcriptome

developmental biology

Francesco J. DeMayo

Institution

Baylor College of Medicine

transcriptome

pulmonary biology

Ju Chen

Institution

University of California, San Diego

naxos disease

pathology

Hugo J Bellen

Institution

Baylor College of Medicine

neurogenetics

neurodevelopmental disorder

Clifford Steer

Institution

University of Minnesota

gene editing

stem cell

Huda Yahya Zoghbi

Institution

Baylor College of Medicine

degenerative pathology

neurodevelopmental disorder

Andrea Ballabio, M.D

Institution

Baylor College of Medicine

lysosomal storage disorders

disease mechanism

Martin M. Matzuk, M.D., Ph.D.

Institution

Baylor College of Medicine

gynecology

developmental biology

Jonathan D. Wren, Ph.D.

Institution

University of Oklahoma

pediatrics

developmental behavioral pediatrics

Mario Medvedovic

Institution

University of Cincinnati

omics datasets

epigenetics