Faculty

Institution

Unit

Venue

Mario Medvedovic

Professor

University of Cincinnati

Affiliations

College of Medicine

Biostatistics, Health Informatics & Data Sciences

Environmental & Public Health Sciences

College of Engineering & Applied Science

Computer Science

Mario Medvedovic is currently serving as a Biostatistics, Health Informatics & Data Sciences Professor at University of Cincinnati.

Honors

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Experiences

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Education

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Mario Medvedovic

University of Cincinnati

Professor

You can click a keyword to filter the displayed items

genetics cell biology gene expression molecular biology pharmacology tumor biology bioinformatics oncology cancer research mammalian biology cancer biology genomics genome biology molecular physiology epigenetics medicinal research oncogenes molecular cancer respiratory medicine cardiovascular research vascular biology membrane biology gene expression profiling microarray data analysis cancer genetics cellular physiology cancer treatment cancer genomics rna biology epigenomics liver physiology molecular metabolism epigenetic changes endocrine research microrna detection gene regulation transcriptomics technology plo biology redox biology avian biology cell regulation transcription regulation cytogenetics cardiovascular physiology gene function gene expression profiles noble rats tumor targeting clinical immunology cardiovascular function protein science comparative endocrinology respiratory toxicology innate immune system chromosome biology molecular regulation endocrine oncology cellular immune responses translational bioinformatics transcriptional signature heme homeostasis genetic testing scientific data management transplant-associated thrombotic microangiopathy omics signatures acute lung injury frontotemporal degeneration cognate sites chromosomal loci radiation-induced rearrangements human cells response system-level cataloging cardiac homeostasis microarray experiments intensity-based hierarchical bayes data portal biomedical informatics molecular diagnostics omics integration biostatistics systems biology omics datasets omics

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cpi203, a Bet Inhibitor, Down-Regulates a Consistent Set of Dna Synthesis Genes Across a Wide Array of Glioblastoma Lines. PLoS ONE (2025)

cancer geneticsgliomasbet inhibitordna synthesis genessystems biologybrain tumor researchmolecular cell biologyneuro-oncologycancer cellsglioblastoma linescancer biologytumor biologycell biology

Inflammatory, Functional, and Compositional Changes of the Uterine Immune Microenvironment in a Lymphangioleiomyomatosis Mouse Model.. PubMed (2025)

immunologycompositional changesimmune mediatorsreproductive immunologycell deathuterine immune microenvironmentlymphangioleiomyomatosis mouse modelimmune responsesimplantation (embryology)immunity (medicine)gynecologyinflammation

Preclinical Evaluation of the Efficacy of a Cyclin-Dependent Kinase Inhibitor Ribociclib in Combination With Letrozole Against Patient-Derived Glioblastoma Cells. Molecular Cancer Therapeutics (2025)

pharmacologygliomasradiation oncologybrain tumor researchmolecular cancerpharmacotherapytherapeutic targetscancer growthanti-cancer agentsoncologyneuro-oncologycancer treatmentpreclinical evaluationtumor biology

The Synthetic Opioid Fentanyl Increases Hiv Replication in Macrophages. PLoS ONE (2025)

immunologyhivopioid use disorderantiviral researchpharmacologyopioid epidemicpharmacotherapyneuropharmacologymolecular pharmacologyapplied pharmacologypharmacological research

Abstract 703: Gaba(a) Receptor Activation Drives Gabarap-Nix Mediated Autophagy to Radiosensitize Primary and Metastatic Lung Adenocarcinoma Tumors. Cancer Research (2024)

Debanjan BhattacharyaRiccardo BarrileDonatien Kamdem ToukamVaibhavkumar S. GawaliLaura KallayTaukir AhmedHawley BrownSepideh RezvanianAniruddha KarvePankaj B. DesaiMario MedvedovicKyle WangDan IonascuNusrat HarunChenran WangAndrew M. BaschnagelJoshua A. KritzerJames CookDaniel A. Pomeranz KrummelSoma Sengupta

receptor activationautophagytumor targetingcancer caremolecular canceranti-cancer agentscancer biologyhealth sciencescancer researchcancer growthcancer treatmenttumor biologyreceptorspharmacologythoracic oncologyradiation oncologyclinical researchoncologygabarap-nix mediated autophagymedicinal research

Accelerating Drug Discovery and Repurposing by Combining Transcriptional Signature Connectivity With Docking. Science Advances (2024)

Alexander W. ThormanJames ReigleSomchai ChutipongtanateJuechen YangBehrouz ShamsaeiMarcin PilarczykMehdi Fazel-NajafabadiRafal AdamczakMichal KourilSurbhi BhatnagarSarah HummelWen NiuArdythe L. MorrowMaria F. Czyzyk-KrzeskaRobert McCullumsmithWilliam SeibelNicolas NassarYi ZhengDavid A. HildemanMario MedvedovicAndrew B. HerrJarek Meller

transcriptional signature connectivitypharmacologymolecular dockingdrug discoverymolecular biologybioinformatics

Coordinated Targeting of S6K1/2 and Axl Disrupts Pyrimidine Biosynthesis in Pten-Deficient Glioblastoma. Cancer Research Communications (2024)

gliomasradiation oncologymolecular cancerbrain tumor researchtumor suppressorstherapeutic targetsmolecular cell biologyanti-cancer agentsaxl disruptspten-deficient glioblastomaneuro-oncologyoncogenescancer cellscancer biologytumor biologycell biology

Cpi203, a Bet Inhibitor, Down-Regulates a Consistent Set of Dna Synthesis Genes Across a Wide Array of Glioblastoma Lines.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Matthew GarrettTroy CarnwathRebecca AlbanoYonghua ZhuangCatherine A. BehrmannMerissa PembertonFarah BarakatRobert LoberMark HoeprichAnthony ParavatiMarilyn ReedHailey SpryDaniel WooEric O'BrienBrett VanCauwenberghJohn PerentesisRani NasserMario MedvedovicDavid Plas

cancer geneticsgene editingdna synthesis genesglioblastoma linesgenome biologybet inhibitormolecular cancercancer genomicsconsistent setanti-cancer agentscancer biologycancer researchwide arraytherapeutic targetstumor biologygene expressionenzyme inhibitionbiomedical engineeringbrain tumor researchgeneticsmolecular biologyoncologymedicinal research

Crosstalk of Map3K1 and Egfr Signaling Mediates Gene-Environment Interactions That Block Developmental Tissue Closure. Journal of Biological Chemistry (2024)

Jingjing WangBo XiaoEiki KimuraMaureen MonganWei-Wen HsuMario MedvedovicAlvaro PugaYing Xia

cell signalingmolecular biologygeneticsdevelopmental biology

Crosstalk of the Map3K1 and Egfr Pathways Mediates Gene-Environment Interactions That Disrupt Developmental Tissue Closure. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jingjing WangBo XiaoEiki KimuraMaureen MonganWei-Wen HsuMario MedvedovicAlvaro PugaYing Xia

gene expressiondevelopmental tissue closuregene-environment interactionsgeneticsegfr pathwaysmolecular biologydevelopmental biologypathway analysis

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Mario Medvedovic

Professor

University of Cincinnati

Affiliations

College of Medicine

Biostatistics, Health Informatics & Data Sciences

Environmental & Public Health Sciences

College of Engineering & Applied Science

Computer Science

Mario Medvedovic is currently serving as a Biostatistics, Health Informatics & Data Sciences Professor at University of Cincinnati.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mario Medvedovic

University of Cincinnati

Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Cpi203, a Bet Inhibitor, Down-Regulates a Consistent Set of Dna Synthesis Genes Across a Wide Array of Glioblastoma Lines. PLoS ONE (2025)

cancer geneticsgliomasbet inhibitordna synthesis genessystems biologybrain tumor researchmolecular cell biologyneuro-oncologycancer cellsglioblastoma linescancer biologytumor biologycell biology

Inflammatory, Functional, and Compositional Changes of the Uterine Immune Microenvironment in a Lymphangioleiomyomatosis Mouse Model.. PubMed (2025)

The Synthetic Opioid Fentanyl Increases Hiv Replication in Macrophages. PLoS ONE (2025)

immunologyhivopioid use disorderantiviral researchpharmacologyopioid epidemicpharmacotherapyneuropharmacologymolecular pharmacologyapplied pharmacologypharmacological research

Abstract 703: Gaba(a) Receptor Activation Drives Gabarap-Nix Mediated Autophagy to Radiosensitize Primary and Metastatic Lung Adenocarcinoma Tumors. Cancer Research (2024)

Accelerating Drug Discovery and Repurposing by Combining Transcriptional Signature Connectivity With Docking. Science Advances (2024)

transcriptional signature connectivitypharmacologymolecular dockingdrug discoverymolecular biologybioinformatics

Coordinated Targeting of S6K1/2 and Axl Disrupts Pyrimidine Biosynthesis in Pten-Deficient Glioblastoma. Cancer Research Communications (2024)

Cpi203, a Bet Inhibitor, Down-Regulates a Consistent Set of Dna Synthesis Genes Across a Wide Array of Glioblastoma Lines.. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Crosstalk of Map3K1 and Egfr Signaling Mediates Gene-Environment Interactions That Block Developmental Tissue Closure. Journal of Biological Chemistry (2024)

Jingjing WangBo XiaoEiki KimuraMaureen MonganWei-Wen HsuMario MedvedovicAlvaro PugaYing Xia

cell signalingmolecular biologygeneticsdevelopmental biology

Crosstalk of the Map3K1 and Egfr Pathways Mediates Gene-Environment Interactions That Disrupt Developmental Tissue Closure. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Jingjing WangBo XiaoEiki KimuraMaureen MonganWei-Wen HsuMario MedvedovicAlvaro PugaYing Xia

gene expressiondevelopmental tissue closuregene-environment interactionsgeneticsegfr pathwaysmolecular biologydevelopmental biologypathway analysis

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10 / page

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Similar Faculty Members

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Institution

University of Oklahoma

pediatrics

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systems biology

Cristian Coarfa

Institution

Baylor College of Medicine

omics

multi-omics studies

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