Faculty

Institution

Unit

Venue

Bhairavi Swaminathan

Research Assistant Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Bhairavi Swaminathan is currently serving as a College Of Medicine Research Assistant Professor at University of Illinois Chicago.

Honors

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Experiences

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Education

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Bhairavi Swaminathan

University of Illinois Chicago

Research Assistant Professor

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immunology vascular biology cell biology cancer biology cancer cells cancer growth cell signaling medicinal research oncogenes angiogenesis cancer discovery signaling pathways genetics developmental biology multiple sclerosis signal transduction cancer treatment gene expression cellular therapy breast oncology membrane biology hematology cardiovascular research cancer care leukemia liver physiology cell regulation cancer management cancer immunosurveillance tumor targeting immunogenetics multiple myeloma intensive care enzyme inhibition variant interpretation cancer genetics lymphatic system lymphoid neoplasia antibody engineering biological microenvironments anti-cancer agents liver cancer neurological progress immunoglobulin levels notch suppression ribosomal gene expression rhoa activity junction activity retinal plexus branching cancer metastasis cardiac endothelium co-translational profiling genetic variation virology medical virology applied physiology cancer imaging molecular cancer host genetics viral genetics cell migration catalyst activation cardiovascular physiology human physiology hemostasis clinical physiology inhibitory activity novel therapies cytokines immune dysregulation interferon beta therapy risk factors endothelial migration murine embryonic lymphangiogenesis unique functions endothelial proliferation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1608: Quantifying Changes to Macrophage Recruitment to the Breast Tumor Microenvironment and Metastasis in Response to Notch4 Blockade. Cancer Research (2025)

immunologyabstract 1608metastasisnotch4 blockadecancer immunosurveillancecellular therapybreast oncologybreast cancerbreast tumor microenvironmentcancer cellstumor microenvironmenttumor biologybiological microenvironmentscell biology

Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium. Cancer research communications (2024)

Jason W.-L EngYu KatoYusuke AdachiBhairavi SwaminathanL. A. NaicheRahul VadakathYoshimasa SakamotoYouya NakazawaSho TachinoKen ItoTakanori AbeYukinori MinoshimaKana Hoshino-NegishiHideaki OgasawaraTomomi KawakatsuMiyuki NishimuraMasahiko KatayamaMasashi ShimizuKazuhiro TaharaToshitaka SatoKatsuhisa SuzukiKishan AgarwalaMasao IwataKenichi NomotoYoichi OzawaToshio ImaiYasuhiro FunahashiJunji MatsuiJan Kitajewski

tumor endotheliumantibody engineeringtumor targetingmedicinecancer carenovel neutralizing antibodiesvascular biologycancer biologycancer researchmurine cancer modelscancer immunotherapycancer growthcancer treatmenttumor biologytumor growthimmunotherapyimmunologyenzyme inhibitionpharmacologyoncologymedicinal researchcellular therapy

Notch Signaling Regulates Unc5B to Suppress Endothelial Proliferation, Migration, Junction Activity, and Retinal Plexus Branching. Scientific Reports (2024)

Qanber RazaTaliha NadeemSeock-Won YounBhairavi SwaminathanAhana GuptaTimothy SargisJing DuHenar CuervoAnne EichmannSusan L. AckermanL. A. NaicheJan Kitajewski

signaling pathwaysgene expressionangiogenesisophthalmologycell migrationendothelial proliferationcell signalingvascular biologymolecular neurosciencejunction activityretinal plexus branchingmembrane biologycatalyst activationsignal transductioncell regulationneurosciencecell biology

Supplementary Figure S3 From Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium. (2024)

Jason W.-L. EngYu KatoYusuke AdachiBhairavi SwaminathanL.A. NaicheRahul VadakathYoshimasa SakamotoYouya NakazawaSho TachinoKen ItoTakanori AbeYukinori MinoshimaKana Hoshino-NegishiHideaki OgasawaraTomomi KawakatsuMiyuki NishimuraMasahiko KatayamaMasashi ShimizuKazuhiro TaharaToshitaka SatoKatsuhisa SuzukiKishan AgarwalaMasao IwataKenichi NomotoYoichi OzawaToshio ImaiYasuhiro FunahashiJunji MatsuiJan Kitajewski

tumor endotheliumnovel therapiesinhibitory activitypathologytumor targetingnovel neutralizing antibodiesvascular biologytumor microenvironmentcancer biologycancer researchmurine cancer modelscancer immunotherapycancer growthtumor biologyimmunotherapytumor growthimmunologycancer discoverymolecular biologyoncogenesmedicinal researchcancer cells

Abstract 4605: Chronic Vegf-C Signaling Exacerbates the Progression of Non-Alcoholic Steatohepatitis and Hepatocarcinoma Through Endothelial Vegfr2 and Vegfr3. Cancer Research (2023)

Seock-Won YounJason W.-L. EngBhairavi SwaminathanPamela TeneqexhiRahul VadakathJan K. Kitajewski

epidemiologychronic vegf-c signalingliver physiologycancer carecancer managementvascular biologymolecular cancercancer biologyhealth sciencesinflammationcancer researchnon-alcoholic steatohepatitiscancer growthhepatologycancer treatmentradiation oncologyliver cancerclinical researchoncologymedicinal research

Abstract Lb009: Notch4 Inhibition by a Novel Neutralizing Antibody Reduces Tumor Progression and Increases Macrophage Recruitment Within the Tumor Microenvironment. Cancer Research (2023)

Jason W. EngL.A. NaicheBhairavi SwaminathanYu KatoKrishna ThakkarKatherine Ann AlexanderRahul VadakathJames H. HertsRajyasree EmmadiJunji MatsuiJan K. Kitajewski

immunologydermatologypharmacologycancer managementcancer researchvascular biologycancer immunosurveillancecancer immunotherapyanti-cancer agentsmacrophage recruitmentnovel neutralizing antibodyoncologymedicinal researchtumor microenvironmentcancer treatmentcancer biologytumor progressionimmunotherapy

Abstract P6-14-10: Jagged-1 Promotes Breast Cancer Metastasis Through the Lymphatic System. Cancer Research (2023)

Benjamin GordonBhairavi SwaminathanLA NaicheJan Kitajewski

neurologypharmacologymetastasiscancer managementradiation oncologycancer researchlymphoid neoplasiabreast canceroncologylymphatic systemmedicinal researchcancer metastasiscancer biologytumor biologybreast oncology

Abstract 13188: Co-Translational Profiling in the Cardiac Endothelium During the Development of Sepsis. Circulation (2022)

Paul GoldspinkChad M WarrenBhairavi SwaminathanPaulina LangaStephanie NiemczykBeata M WolskaJan KitajewskiPieter deTombeR John Solaro

cardiologycardiovascular physiologycardiac endotheliumhematologyemergency medicinecardiovascular researchvascular biologyapplied physiologyhuman physiologyhemostasisco-translational profilingintensive carecritical careclinical physiologysepsishealth sciencestranslational medicineinflammation

Abstract 247: Targeting Notch4 With a Novel Neutralizing Antibody Inhibits Tumor Growth and Alters Immune Cell Populations Within the Tumor Microenvironment. Cancer Research (2022)

Jason EngL.A. NaicheBhairavi SwaminathanYu KatoKrishna ThakkarRahul VadakathJames HertsRajyasree EmmadiJunji MatsuiJan Kitajewski

tumor targetingvascular biologyanti-cancer agentsnovel neutralizing antibodytumor microenvironmentcancer biologydermatologyleukemiacancer researchcancer immunotherapycancer growthcell populationscancer treatmenttumor growthimmunotherapyimmunologypharmacologycancer imagingoncologymedicinal researchcellular therapy

Endothelial Notch Signaling Directly Regulates the Small Gtpase Rnd1 to Facilitate Notch Suppression of Endothelial Migration. Scientific Reports (2022)

Bhairavi SwaminathanSeock-Won YounL. A. NaicheJing DuStephanie R. VillaJordan B. MetzHuijuan FengChaolin ZhangRaphael KopanPeter A. SimsJan K. Kitajewski

endothelial migrationvascular biologydevelopmental biologymembrane biologynotch suppressioncell biology

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Bhairavi Swaminathan

Research Assistant Professor

University of Illinois Chicago

Affiliations

College of Medicine

Department of Physiology and Biophysics

Bhairavi Swaminathan is currently serving as a College Of Medicine Research Assistant Professor at University of Illinois Chicago.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Bhairavi Swaminathan

University of Illinois Chicago

Research Assistant Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Abstract 1608: Quantifying Changes to Macrophage Recruitment to the Breast Tumor Microenvironment and Metastasis in Response to Notch4 Blockade. Cancer Research (2025)

Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium. Cancer research communications (2024)

Notch Signaling Regulates Unc5B to Suppress Endothelial Proliferation, Migration, Junction Activity, and Retinal Plexus Branching. Scientific Reports (2024)

Qanber RazaTaliha NadeemSeock-Won YounBhairavi SwaminathanAhana GuptaTimothy SargisJing DuHenar CuervoAnne EichmannSusan L. AckermanL. A. NaicheJan Kitajewski

Supplementary Figure S3 From Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium. (2024)

Abstract 4605: Chronic Vegf-C Signaling Exacerbates the Progression of Non-Alcoholic Steatohepatitis and Hepatocarcinoma Through Endothelial Vegfr2 and Vegfr3. Cancer Research (2023)

Seock-Won YounJason W.-L. EngBhairavi SwaminathanPamela TeneqexhiRahul VadakathJan K. Kitajewski

Abstract Lb009: Notch4 Inhibition by a Novel Neutralizing Antibody Reduces Tumor Progression and Increases Macrophage Recruitment Within the Tumor Microenvironment. Cancer Research (2023)

Jason W. EngL.A. NaicheBhairavi SwaminathanYu KatoKrishna ThakkarKatherine Ann AlexanderRahul VadakathJames H. HertsRajyasree EmmadiJunji MatsuiJan K. Kitajewski

Abstract P6-14-10: Jagged-1 Promotes Breast Cancer Metastasis Through the Lymphatic System. Cancer Research (2023)

Benjamin GordonBhairavi SwaminathanLA NaicheJan Kitajewski

Abstract 13188: Co-Translational Profiling in the Cardiac Endothelium During the Development of Sepsis. Circulation (2022)

Paul GoldspinkChad M WarrenBhairavi SwaminathanPaulina LangaStephanie NiemczykBeata M WolskaJan KitajewskiPieter deTombeR John Solaro

Abstract 247: Targeting Notch4 With a Novel Neutralizing Antibody Inhibits Tumor Growth and Alters Immune Cell Populations Within the Tumor Microenvironment. Cancer Research (2022)

Jason EngL.A. NaicheBhairavi SwaminathanYu KatoKrishna ThakkarRahul VadakathJames HertsRajyasree EmmadiJunji MatsuiJan Kitajewski

Endothelial Notch Signaling Directly Regulates the Small Gtpase Rnd1 to Facilitate Notch Suppression of Endothelial Migration. Scientific Reports (2022)

Bhairavi SwaminathanSeock-Won YounL. A. NaicheJing DuStephanie R. VillaJordan B. MetzHuijuan FengChaolin ZhangRaphael KopanPeter A. SimsJan K. Kitajewski

endothelial migrationvascular biologydevelopmental biologymembrane biologynotch suppressioncell biology

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4
5
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cellular therapy

immune response

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