Faculty

Institution

Unit

Venue

Stephen Cannon

Professor

University of California, Los Angeles

Affiliations

David Geffen School of Medicine

Physiology

Stephen Cannon is currently serving as a David Geffen School Of Medicine Professor at University of California, Los Angeles.

Honors

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Experiences

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Education

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Stephen Cannon

University of California, Los Angeles

Professor

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neuroscience neurology physiology neurophysiology electrophysiology membrane biology molecular physiology genetics skeletal muscle cellular physiology periodic paralysis hypokalemic periodic paralysis human physiology mammalian biology gene expression muscle function neuroanatomy neurogenetics animal physiology applied physiology protein science clinical research clinical investigation disease physiology physiological research clinical physiology molecular neuroscience liver physiology movement disorders vascular biology mammalian physiology membrane transport neuromusculoskeletal disorders hypokalaemic periodic paralysis sodium channels musculoskeletal disorders membrane science cellular neurobiology musculoskeletal science orthopedic biomechanics clinical medicine genetic disorders mutagenesis translational physiology sarcopenia protein transport experimental pharmacology neurotransmission hyperpolarization (biology) non-dystrophic myotonias muscle force peptides nucleic acids medicinal research applied pharmacology protein function long non-coding rna rna biology brain science neuroinflammation clinical neuroscience receptor (biochemistry) neural science human sciences knockout mice muscle injury primary periodic paralyses functional receptor molecular pathogenesis proton-selective gating pore sodium channelopathies voltage-sensor mutations familial periodic paralysis defective slow inactivation non-dystrophic myotonia prospective study

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Molecular Dynamics Simulations of Nav1.4 in a Closed-State Conformation Reveal Voltage Sensor Dynamics. Biophysical Journal (2026)

biophysicsmolecular sciencemolecular physicsmolecular biophysicsmolecular modelsphysicsion structurecomputational biophysicsmolecular modelling

Efficacy of a K + Channel Agonist, Xen1101, for Preserving Contractility in Mouse Models of Hypokalemic Periodic Paralysis. Muscle & Nerve (2026)

neuromodulation (medicine)circulatory physiologyneuropharmacologypharmacological researchmouse modelshypokalemic periodic paralysiselectrophysiologyexperimental pharmacologypharmacologyphysiologyneurotransmissionmolecular pharmacologyexperimental medicineneurophysiologymolecular physiologyhyperpolarization (biology)

Bps2025 - Molecular Dynamics Simulation of the Sodium Channel Nav1.4 in a Closed-State Conformation. Biophysical Journal (2025)

biophysicsclosed-state conformationmolecular mechanicsmolecular sciencemolecular physicsmolecular biophysicsmolecular dynamics simulationmolecular modelsphysicsion structurecomputational biophysicsmolecular modellingsodium channel nav1.4

Potassium-Sensitive Loss of Muscle Force in the Setting of Reduced Inward Rectifier K + Current: Implications for Andersen–Tawil Syndrome. Proceedings of the National Academy of Sciences (2025)

Nathaniel EliaMarbella QuiñonezFenfen WuEkaterina MokhonovaMarino DiFrancoMelissa J. SpencerStephen C. Cannon

biophysicsmuscle forcepotassium-sensitive lossandersen-tawil syndrome

The Molecular Transition That Confers Voltage Dependence to Muscle Contraction. Nature Communications (2025)

Marina AngeliniNicoletta SavalliFederica SteccanellaSavana MaxfieldSerena PozziMarino DiFrancoStephen C CannonAntonios PantazisRiccardo Olcese

molecular biologymolecular transition

Periodic Paralysis. Handbook of clinical neurology (2024)

Stephen C Cannon

neurosciencecentral nervous systemclinical neurologyperiodic paralysisneurology

Retigabine Suppresses Loss of Force in Mouse Models of Hypokalaemic Periodic Paralysis. Brain (2023)

Marbella QuiñonezMarino DiFrancoFenfen WuStephen C Cannon

mouse modelshypokalaemic periodic paralysiscentral nervous systemneuroscienceneurology

A Multicenter, Prospective, Cross-Sectional, Genotype-Phenotype and Longitudinal Natural History Study of Andersen-Tawil Syndrome. medRxiv (2022)

Sanjeev RajakulendranMartin Tristani-FirouziReza SadjadiJames ClelandRabi TawilGiovanni MeolaValeria SansoneJaya TrivediStephen C CannonMichael G HannaRobert C. Griggs

geneticsgenetic epidemiologyhealth sciencesandersen-tawil syndromeepidemiology

Functional Rescue of Periodic Paralysis by in Vivo Gene Editing of Cav1.1. Biophysical Journal (2022)

Fen Fen WuMarbella QuinonezSteve C. Cannon

biophysicsgene editingperiodic paralysisbiophysical chemistrybiophysical review

Voltage-Dependent Ca 2+ Release is Impaired in Hypokalemic Periodic Paralysis Caused by Ca V 1.1-R528H but Not by Na V 1.4-R669h. American Journal of Physiology-Cell Physiology (2022)

Marino DiFrancoStephen C. Cannon

hypokalemic periodic paralysiselectrophysiologyneurosciencepharmacologyneurology

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Stephen Cannon

Professor

University of California, Los Angeles

Affiliations

David Geffen School of Medicine

Physiology

Stephen Cannon is currently serving as a David Geffen School Of Medicine Professor at University of California, Los Angeles.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Stephen Cannon

University of California, Los Angeles

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Bps2026 – Molecular Dynamics Simulations of Nav1.4 in a Closed-State Conformation Reveal Voltage Sensor Dynamics. Biophysical Journal (2026)

biophysicsmolecular sciencemolecular physicsmolecular biophysicsmolecular modelsphysicsion structurecomputational biophysicsmolecular modelling

Efficacy of a K + Channel Agonist, Xen1101, for Preserving Contractility in Mouse Models of Hypokalemic Periodic Paralysis. Muscle & Nerve (2026)

Bps2025 - Molecular Dynamics Simulation of the Sodium Channel Nav1.4 in a Closed-State Conformation. Biophysical Journal (2025)

Potassium-Sensitive Loss of Muscle Force in the Setting of Reduced Inward Rectifier K + Current: Implications for Andersen–Tawil Syndrome. Proceedings of the National Academy of Sciences (2025)

Nathaniel EliaMarbella QuiñonezFenfen WuEkaterina MokhonovaMarino DiFrancoMelissa J. SpencerStephen C. Cannon

biophysicsmuscle forcepotassium-sensitive lossandersen-tawil syndrome

The Molecular Transition That Confers Voltage Dependence to Muscle Contraction. Nature Communications (2025)

Marina AngeliniNicoletta SavalliFederica SteccanellaSavana MaxfieldSerena PozziMarino DiFrancoStephen C CannonAntonios PantazisRiccardo Olcese

molecular biologymolecular transition

Periodic Paralysis. Handbook of clinical neurology (2024)

Stephen C Cannon

neurosciencecentral nervous systemclinical neurologyperiodic paralysisneurology

Retigabine Suppresses Loss of Force in Mouse Models of Hypokalaemic Periodic Paralysis. Brain (2023)

Marbella QuiñonezMarino DiFrancoFenfen WuStephen C Cannon

mouse modelshypokalaemic periodic paralysiscentral nervous systemneuroscienceneurology

A Multicenter, Prospective, Cross-Sectional, Genotype-Phenotype and Longitudinal Natural History Study of Andersen-Tawil Syndrome. medRxiv (2022)

Sanjeev RajakulendranMartin Tristani-FirouziReza SadjadiJames ClelandRabi TawilGiovanni MeolaValeria SansoneJaya TrivediStephen C CannonMichael G HannaRobert C. Griggs

geneticsgenetic epidemiologyhealth sciencesandersen-tawil syndromeepidemiology

Functional Rescue of Periodic Paralysis by in Vivo Gene Editing of Cav1.1. Biophysical Journal (2022)

Fen Fen WuMarbella QuinonezSteve C. Cannon

biophysicsgene editingperiodic paralysisbiophysical chemistrybiophysical review

Voltage-Dependent Ca 2+ Release is Impaired in Hypokalemic Periodic Paralysis Caused by Ca V 1.1-R528H but Not by Na V 1.4-R669h. American Journal of Physiology-Cell Physiology (2022)

Marino DiFrancoStephen C. Cannon

hypokalemic periodic paralysiselectrophysiologyneurosciencepharmacologyneurology

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Similar Faculty Members

Michela Ottolia

Institution

University of California, Los Angeles

molecular physiology

cellular physiology

Professor Wei Chen

Institution

University of South Florida

electrophysiology

electrical mobility

Barbara Horwitz

Institution

University of California, Davis

metabolism

oxidative stress

Glenna C. Bett

Institution

University at Buffalo

membrane

membrane transport

Jeffrey R. Balser

Institution

Vanderbilt University

excitation-contraction coupling

electrophysiology

Scott Earley

Institution

University of Nevada, Reno

transient receptor potential

cerebral blood flow

Ki Ho Park

Institution

University of Virginia

molecular physiology

cell biology

Taben Hale, PhD

Institution

University of Arizona

autonomic dysfunction

cardiovascular disease

Sean Newsom

Institution

Oregon State University

energy metabolism

metabolic diseases

Robin Shaw

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University of Utah

developmental biology

gene therapy