Faculty

Institution

Unit

Venue

Sean S. Davies

Associate Professor

Vanderbilt University

Affiliations

School of Medicine

Department of Pharmacology

Sean S. Davies is currently serving as a Pharmacology Associate Professor at Vanderbilt University.

Honors

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Experiences

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Education

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Sean S. Davies

Vanderbilt University

Associate Professor

You can click a keyword to filter the displayed items

pharmacology immunology health sciences biochemistry redox biology membrane biology free radical biology hematology oxidative stress cardiology inflammation hypertension cardiovascular research lipids protein science clinical lipidology lipid chemistry respiratory medicine lipid peroxidation lipid science biological chemistry enzyme inhibition medicinal chemistry medicinal research liver physiology blood pressure redox signaling mammalian biology molecular physiology cardiovascular physiology reactive g-ketoaldehydes renal function clinical microbiology lipid analysis lipoprotein metabolism cytokines reperfusion injury isoprostane pathway systemic lupus erythematosus mitochondrial dysfunction applied microbiology clinical biochemistry clinical investigation treatment and prevention lipid disorders antihypertensive therapy mitochondrial function older adults dendritic cells reactive isolevuglandins clinical medicine protein chemistry cardiovascular pharmacology pharmacokinetics medical biophysics biomolecular interactions hyperlipidemia clinical immunology nutrient physiology t-regulatory cell healthy aging biogerontology cardiovascular function molecular immunology renal pathophysiology proteinlipid interaction immune dysregulation reactive dicarbonyls diet-induced obesity dicarbonyl-modified lipoproteins food intake clinical relevance dc isoketal-modified proteins dietary components microbial metabolism isoprostane generation gut-organ axis dysbiosis microbiology gut microbiota microbiome therapeutic modification

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dysfunctional Hdl Promotes Platelet Apoptosis and Thrombosis in Familial Hypercholesterolemia. medRxiv (2025)

Karthik DhanabalanHonglei LiPatricia G. YanceySergey SolomevichJiyu LiYanshuang LiJiansheng HuangConnor DennewitzChunyan WangHuan TaoLoren E SmithDavid GailaniDaria SalamevichKejun ShaoJing DuKathleen A MartinJohn HwaSean S DaviesMacRae F LintonWen-Liang Song

dysfunctional hdl promotescell deathdisease progressionthrombosishematologyblood plateletmedicinefamilial hypercholesterolemia

N-Aldehyde-Modified Phosphatidylethanolamines Generated by Lipid Peroxidation Are Robust Substrates of N-Acyl Phosphatidylethanolamine Phospholipase D. Journal of Lipid Research (2025)

lipidslipid chemistryrobust substrateslipid peroxidationbiochemistrybioorganic chemistrybiochemical sciencesoxidative stressfree radical biologyn-aldehyde-modified phosphatidylethanolaminesbiomolecular engineering

Isolevuglandins Promote Mitochondrial Dysfunction and Electrophysiologic Abnormalities in Atrial Cardiomyocytes. Cells (2024)

Tuerdi SubatiZhenjiang YangMatthew B. MurphyJoshua M. StarkDavid Z. TrykallSean S. DaviesJoey V. BarnettKatherine T. Murray

cell physiologycardiovascular researchmitochondrial dysfunctioncardiologyatrial cardiomyocytesmuscle functionelectrophysiologycell biologyneurosciencecellular physiologyelectrophysiologic abnormalitiesmolecular physiologymembrane biologyneurophysiologycellular biologymitochondrial functiongenetics

N-Aldehyde-Modified Phosphatidylethanolamines Generated by Lipid Peroxidation Are Robust Substrates of N-Acyl Phosphatidylethanolamine Phospholipase D. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Reza FadaeiAnnie C. BernsteinAndrew N. JenkinsAllison G. PickensJonah E. ZarrowAbdul-Musawwir Alli-OluwafuyiKeri A. TallmanSean S. Davies

enzymeslipid peroxidationredox biologybiochemistrychemical biologychemistrymolecular biologyenzyme inhibitionn-aldehyde-modified phosphatidylethanolamines

Plaat1L1 Controls Feeding Induced Nape Biosynthesis and Contributes to Energy Balance Regulation in Zebrafish. Prostaglandins & Other Lipid Mediators (2024)

Zahra MashhadiLinlin YinNoura S. DosokyWenbiao ChenSean S. Davies

animal physiologyfish biologyphysiologyanimal biotechnologydevelopmental biologyavian biologypharmacologyenergy balance regulationbiosynthesis

Posttranslationally Modified Self-Peptides Promote Hypertension in Mouse Models. Journal of Clinical Investigation (2024)

Nathaniel BloodworthWei ChenKuniko HunterDavid PatrickAmy PalubinskyElizabeth PhillipsDaniel RoethMarkus KalkumSimon MallalSean DaviesMingfang AoRocco MorettiJens MeilerDavid G. Harrison

physiologyhypothalamic peptideclinical investigationpeptidesmouse modelsself-peptides promote hypertensionclinical researchpharmacologysystems biologyhypertension

Serum Isolevuglandin Igg Antibody Concentrations Are Increased in Patients With Systemic Lupus Erythematosus and Associated With Lower 24-Hour Blood Pressure. Frontiers in Lupus (2024)

Anastasiia PhothisaneAnnette M. OeserShahensha ShaikQiong WuOlivia PoseySean S. DaviesJaya KrishnanDavid M. PatrickC. Michael SteinMichelle J. Ormseth

epidemiologyrheumatologyclinical rheumatologyclinical immunologyimmunologyhematologysystemic lupus erythematosusautoimmune diseaseshypertension

Abstract 074: Discovery of Post-Translationally Modified Self-Peptides Responsible for T-Cell Autoimmunity in Hypertension. Hypertension (2023)

Nathaniel BloodworthWei ChenDavid M PatrickMingfang AoRocco MorettiJens MeilerSean S DaviesDavid G Harrison

immunologyt-cell autoimmunitymedicinepharmacologyimmunologic mechanismshypertension

Discovery of Post-Translationally Modified Self-Peptides That Promote Hypertension. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Nathaniel BloodworthWei ChenDavid PatrickAmy PalubinskyElizabeth PhillipsDaniel RoethMarkus KalkumSimon MallalSean DaviesMingfang AoRocco MorettiJens MeilerDavid G Harrison

biological engineeringprotein sciencetranslational medicinemolecular biologypharmacologydrug discoveryhypertension

Dr. L. Jackson Roberts II. Free Radical Biology and Medicine (2023)

Sean S. DaviesJoshua P. FesselGinger L. MilneKevin MooreHuiyong Yin

biologymedicineoxidative stressfree radical biologyhealth sciences

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Sean S. Davies

Associate Professor

Vanderbilt University

Affiliations

School of Medicine

Department of Pharmacology

Sean S. Davies is currently serving as a Pharmacology Associate Professor at Vanderbilt University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Sean S. Davies

Vanderbilt University

Associate Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dysfunctional Hdl Promotes Platelet Apoptosis and Thrombosis in Familial Hypercholesterolemia. medRxiv (2025)

dysfunctional hdl promotescell deathdisease progressionthrombosishematologyblood plateletmedicinefamilial hypercholesterolemia

N-Aldehyde-Modified Phosphatidylethanolamines Generated by Lipid Peroxidation Are Robust Substrates of N-Acyl Phosphatidylethanolamine Phospholipase D. Journal of Lipid Research (2025)

Isolevuglandins Promote Mitochondrial Dysfunction and Electrophysiologic Abnormalities in Atrial Cardiomyocytes. Cells (2024)

Tuerdi SubatiZhenjiang YangMatthew B. MurphyJoshua M. StarkDavid Z. TrykallSean S. DaviesJoey V. BarnettKatherine T. Murray

Reza FadaeiAnnie C. BernsteinAndrew N. JenkinsAllison G. PickensJonah E. ZarrowAbdul-Musawwir Alli-OluwafuyiKeri A. TallmanSean S. Davies

enzymeslipid peroxidationredox biologybiochemistrychemical biologychemistrymolecular biologyenzyme inhibitionn-aldehyde-modified phosphatidylethanolamines

Plaat1L1 Controls Feeding Induced Nape Biosynthesis and Contributes to Energy Balance Regulation in Zebrafish. Prostaglandins & Other Lipid Mediators (2024)

Zahra MashhadiLinlin YinNoura S. DosokyWenbiao ChenSean S. Davies

animal physiologyfish biologyphysiologyanimal biotechnologydevelopmental biologyavian biologypharmacologyenergy balance regulationbiosynthesis

Posttranslationally Modified Self-Peptides Promote Hypertension in Mouse Models. Journal of Clinical Investigation (2024)

Nathaniel BloodworthWei ChenKuniko HunterDavid PatrickAmy PalubinskyElizabeth PhillipsDaniel RoethMarkus KalkumSimon MallalSean DaviesMingfang AoRocco MorettiJens MeilerDavid G. Harrison

physiologyhypothalamic peptideclinical investigationpeptidesmouse modelsself-peptides promote hypertensionclinical researchpharmacologysystems biologyhypertension

Serum Isolevuglandin Igg Antibody Concentrations Are Increased in Patients With Systemic Lupus Erythematosus and Associated With Lower 24-Hour Blood Pressure. Frontiers in Lupus (2024)

Anastasiia PhothisaneAnnette M. OeserShahensha ShaikQiong WuOlivia PoseySean S. DaviesJaya KrishnanDavid M. PatrickC. Michael SteinMichelle J. Ormseth

epidemiologyrheumatologyclinical rheumatologyclinical immunologyimmunologyhematologysystemic lupus erythematosusautoimmune diseaseshypertension

Abstract 074: Discovery of Post-Translationally Modified Self-Peptides Responsible for T-Cell Autoimmunity in Hypertension. Hypertension (2023)

Nathaniel BloodworthWei ChenDavid M PatrickMingfang AoRocco MorettiJens MeilerSean S DaviesDavid G Harrison

immunologyt-cell autoimmunitymedicinepharmacologyimmunologic mechanismshypertension

Discovery of Post-Translationally Modified Self-Peptides That Promote Hypertension. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Nathaniel BloodworthWei ChenDavid PatrickAmy PalubinskyElizabeth PhillipsDaniel RoethMarkus KalkumSimon MallalSean DaviesMingfang AoRocco MorettiJens MeilerDavid G Harrison

biological engineeringprotein sciencetranslational medicinemolecular biologypharmacologydrug discoveryhypertension

Dr. L. Jackson Roberts II. Free Radical Biology and Medicine (2023)

Sean S. DaviesJoshua P. FesselGinger L. MilneKevin MooreHuiyong Yin

biologymedicineoxidative stressfree radical biologyhealth sciences

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10 / page

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cardiovascular translational research

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free radical biology

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