Faculty

Institution

Unit

Venue

Thomas M. McIntyre

Professor

Case Western Reserve University

Affiliations

Medicine

Cardiovascular Medicine

School of Medicine

Medicine

Thomas M. Mcintyre is currently serving as a Cardiovascular Medicine Professor at Case Western Reserve University.

Honors

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Experiences

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Education

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Thomas M. McIntyre

Case Western Reserve University

Professor

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pharmacology immunology hematology cell biology vascular biology membrane biology inflammation biochemistry liver physiology hemostasis biological chemistry enzymes cardiology redox biology platelet-activating factor medicinal research gene expression protein science nephrology cell signaling thrombosis clinical lipidology biochemical sciences cardiovascular research blood platelet clinical investigation cellular physiology respiratory medicine molecular physiology circulatory physiology endothelial cells lipoprotein metabolism clinical biochemistry clinical physiology clinical medicine angiogenesis innate immune system endothelial dysfunction lipid science angiology cancer biology platelet-activating factor acetylhydrolase cell adhesion human endothelial cells host response chronic inflammation vascular disease lipid chemistry renal function apoptosis cytokines redox signaling cellular biology transcription regulation molecular regulation clinical immunology protein expression medical biophysics cellular enzymology molecular immunology cell regulation cell-matrix interactions anti-inflammatory heme homeostasis human neutrophils molecular cloning low density lipoprotein activated human platelets human plasma paf acetylhydrolase lysophosphatidic acid signal-dependent translation neutrophil adherence inflammatory cytokines low-density lipoprotein cell-cell interactions physiology inflammatory cells oxidative stress free radical biology cell death lipid peroxidation

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dysregulated Platelet Function in Patients With Postacute Sequelae of Covid-19. Vascular Medicine (2024)

Anu AggarwalTamanna K SinghMichael PhamMatthew GodwinRui ChenThomas M McIntyreAlliefair ScaliseMina K ChungCourtney JenningsMariya AliHiijun ParkKristin EnglundAlok A KhoranaLars G SvenssonSamir KapadiaKeith R McCraeScott J Cameron

neurologyinflammationcardiologyvascular biologynephrologycardiovascular researchclinical lipidologycirculatory physiologyvascular diseaseangiologyviral pathogenesispostacute sequelaehematologyneurosciencehemostasismedicinecovid-19platelet function

D-2-Hydroxyglutarate Inhibits Calcineurin Phosphatase Activity to Abolish Nf-at Activation and Il-2 Induction in Stimulated Lymphocytes. The Journal of Immunology (2023)

Faezeh AfsariThomas M. McIntyre

nf-at activationcell signalingimmunologyimmune responsesenzyme inhibitionstimulated lymphocytes

Data From Adamdec1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells. (2023)

Ana Jimenez-PascualJames S. HaleAnja KordowskiJamie PughDaniel J. SilverDefne BayikGustavo RoversiTyler J. AlbanShilpa RaoRui ChenThomas M. McIntyreGiorgio ColomboGiulia TarabolettiKarl O. HolmbergKarin Forsberg-NilssonJustin D. LathiaFlorian A. Siebzehnrubl

growth factortumor biologycancer biologycell biologycancer researchdata sciencegenetics

Covid-19 Plasma Exosomes Promote Proinflammatory Immune Responses in Peripheral Blood Mononuclear Cells. Scientific Reports (2022)

Lechuang ChenRui ChenMin YaoZhimin FengGuoxiang YuanFengchun YeKien NguyenJonathan KarnGrace A. McComseyThomas M. McIntyreGe Jin

inflammationimmunologycell biologyproinflammatory immune responsescovid-19health sciences

Effect of Aspirin on Short-Term Outcomes in Hospitalized Patients With Covid-19. Vascular Medicine (2021)

Aditya SahaiRohan BhandariMatthew GodwinThomas McIntyreMina K ChungJean-Pierre IskandarHayaan KamranEssa HaririAnu AggarwalRobert BurtonAnkur KalraJohn R BartholomewKeith R McCraeAyman ElbadawiJames BenaLars G SvenssonSamir KapadiaScott J Cameron

cardiovascular diseasehealth carecardiologyvascular diseaserespiratory medicinehospitalized patientsoutcomes researchmedicineintensive carecovid-19short-term outcomesemergency medicinecritical care

Different Glycoforms of Alpha-1-Acid Glycoprotein Contribute to Its Functional Alterations in Platelets and Neutrophils. Journal of Leukocyte Biology (2020)

Mosale Seetharam SumanthShancy P JacobKandahalli Venkataranganayaka AbhilashaBhanu Kanth ManneVenkatesha BasrurSylvain LehouxRobert A CampbellChristian C YostThomas M McIntyreRichard D CummingsAndrew S WeyrichMatthew T RondinaGopal K Marathe

dermatologyhemostasisblood plateletvascular biologyclinical lipidologynephrologycarbohydrate-protein interactionsphysiologycell biologyhematologymembrane proteinscellular physiologyglycobiologyfunctional modificationfunctional alterationscardiovascular researchdifferent glycoformsheme homeostasismolecular physiologymembrane biology

Differential Glycosylation of Alpha-1-Acid Glycoprotein (Agp-1) Contributes to Its Functional Diversity. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Mosale Seetharam SumanthShancy P JacobKandahalli Venkataranganayaka AbhilashaBhanu Kanth ManneVenkatesha BasrurSylvain LehouxRobert A CampbellChristian C YostMatthew T RhondinaThomas M McIntyreRichard D CummingsAndrew S WeyrichGopal K Marathe

carbohydrate-protein interactionsprotein chemistryprotein scienceglycosylationcell biologybiochemistryglycobiologyfunctional diversitymembrane biologymolecular biologydifferential glycosylationcarbohydrate chemistry

Sars-Cov-2 Receptors Are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in Covid-19 Patients. Research Square (Research Square) (2020)

Aditya SahaiRohan BhandariMilka KoupenovaJane FreedmanMathew GodwinThomas McIntyreMina ChungJean-Pierre IskandarHayaan KamranAnu AggarwalAnkur KalraJohn BartholomewKeith McCraeAyman ElbadawiLars SvenssonSamir KapadiaEssa HaririScott Cameron

clinical outcomesepidemiologyclinical evidenceimmunologyrespiratory medicinemedicinal researchhematologyplatelet antagonistsars-cov-2antiviral therapyclinical researchpharmacologyblood platelethuman plateletscovid-19pharmacotherapyanticoagulantsvirus research

Acute Phase Protein, α – 1- Acid Glycoprotein (Agp-1), Has Differential Effects on Tlr-2 and Tlr-4 Mediated Responses. Immunobiology (2019)

Mosale Seetharam SumanthKandahalli Venkataranganayaka AbhilashaShancy Petsel JacobVyala Hanumanthareddy ChaithraVenkatesha BasrurBelinda WillardThomas M. McIntyreK. Sandeep PrabhuGopal K. Marathe

acute phase proteinimmunologyimmune responsesmedicineadaptive immune systemdifferential effects

Adamdec1 Maintains a Novel Growth Factor Signaling Loop in Cancer Stem Cells. bioRxiv (Cold Spring Harbor Laboratory) (2019)

James S. HaleAna Jimenez-PascualAnja KordowskiJamie PughShilpa RaoDaniel J. SilverTyler AlbanDefne Bayik WatsonRui ChenThomas M. McIntyreGiorgio ColomboGiulia TarabolettiKarl O. HolmbergKarin Forsberg-NilssonJustin D. LathiaFlorian A. Siebzehnrubl

tumor biologystem cell researchcell signalingcancer stem cellscell biologymedicinal researchsignaling pathwayscarcinogenesiscancer researchnovel growth factormolecular biologypharmacologygene expressioncancer biology

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Thomas M. McIntyre

Professor

Case Western Reserve University

Affiliations

Medicine

Cardiovascular Medicine

School of Medicine

Medicine

Thomas M. Mcintyre is currently serving as a Cardiovascular Medicine Professor at Case Western Reserve University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Thomas M. McIntyre

Case Western Reserve University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Dysregulated Platelet Function in Patients With Postacute Sequelae of Covid-19. Vascular Medicine (2024)

D-2-Hydroxyglutarate Inhibits Calcineurin Phosphatase Activity to Abolish Nf-at Activation and Il-2 Induction in Stimulated Lymphocytes. The Journal of Immunology (2023)

Faezeh AfsariThomas M. McIntyre

nf-at activationcell signalingimmunologyimmune responsesenzyme inhibitionstimulated lymphocytes

Data From Adamdec1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells. (2023)

growth factortumor biologycancer biologycell biologycancer researchdata sciencegenetics

Covid-19 Plasma Exosomes Promote Proinflammatory Immune Responses in Peripheral Blood Mononuclear Cells. Scientific Reports (2022)

Lechuang ChenRui ChenMin YaoZhimin FengGuoxiang YuanFengchun YeKien NguyenJonathan KarnGrace A. McComseyThomas M. McIntyreGe Jin

inflammationimmunologycell biologyproinflammatory immune responsescovid-19health sciences

Effect of Aspirin on Short-Term Outcomes in Hospitalized Patients With Covid-19. Vascular Medicine (2021)

cardiovascular diseasehealth carecardiologyvascular diseaserespiratory medicinehospitalized patientsoutcomes researchmedicineintensive carecovid-19short-term outcomesemergency medicinecritical care

Different Glycoforms of Alpha-1-Acid Glycoprotein Contribute to Its Functional Alterations in Platelets and Neutrophils. Journal of Leukocyte Biology (2020)

Differential Glycosylation of Alpha-1-Acid Glycoprotein (Agp-1) Contributes to Its Functional Diversity. bioRxiv (Cold Spring Harbor Laboratory) (2020)

Sars-Cov-2 Receptors Are Expressed on Human Platelets and the Effect of Aspirin on Clinical Outcomes in Covid-19 Patients. Research Square (Research Square) (2020)

Acute Phase Protein, α – 1- Acid Glycoprotein (Agp-1), Has Differential Effects on Tlr-2 and Tlr-4 Mediated Responses. Immunobiology (2019)

Mosale Seetharam SumanthKandahalli Venkataranganayaka AbhilashaShancy Petsel JacobVyala Hanumanthareddy ChaithraVenkatesha BasrurBelinda WillardThomas M. McIntyreK. Sandeep PrabhuGopal K. Marathe

acute phase proteinimmunologyimmune responsesmedicineadaptive immune systemdifferential effects

Adamdec1 Maintains a Novel Growth Factor Signaling Loop in Cancer Stem Cells. bioRxiv (Cold Spring Harbor Laboratory) (2019)

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