Faculty

Institution

Unit

Venue

Robert Nicholas

Professor & Vice Chair for Research and Education

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Pharmacology

Robert Nicholas is currently serving as a Pharmacology Professor & Vice Chair for Research and Education at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Robert Nicholas

University of North Carolina at Chapel Hill

Professor & Vice Chair for Research and Education

You can click a keyword to filter the displayed items

pharmacology biochemistry receptors clinical microbiology molecular biology infectious diseases protein science biological chemistry microbial pathogenesis gene expression cell signaling structural biology enzymes membrane biology protein structure receptor (biochemistry) molecular microbiology protein chemistry veterinary microbiology applied microbiology microbial genetics venereology structural molecular biology bacteriology medical microbiology infection control antibiotic resistance escherichia coli biochemical sciences molecular physiology medicinal research protein function cellular physiology emerging infectious diseases avian biology enzyme inhibition host genetics experimental pharmacology mammalian biology pharmacokinetics biochemical genetics diagnostic microbiology penicillin-binding proteins neisseria gonorrhoeae expanded-spectrum cephalosporins antimicrobial agents biomolecular structure pathway analysis cell physiology mutagenesis protein expression crystal structures host specificity protein transport resistance mutation (virology) microbial diversity pharmaceutical chemistry clinical pharmacology amino acids pilq secretin antimicrobial susceptibility molecular neurobiology molecular research treatment effects biomolecular interactions clinical infectious disease treatment failure penicillin resistance human granulocytes b-lactam antibiotics soluble form penicillin-binding protein substrate specificity sxn motif mycobacterium tuberculosis untreatable gonorrhea antimicrobial resistance drug resistance pathogenic bacteria microbiology

Notable Scholarly Works

Notable Federal Grants

Collaborators

Development and Validation of Multiplex Assays for Mouse and Human Igg and Iga to Neisseria Gonorrhoeae Antigens. The Journal of Infectious Diseases (2024)

Erica L StoverMarguerite B LittleKristie L ConnollyLixin LiRobert A NicholasAleksandra E SikoraAnn E JerseMarcia M HobbsJ Alex DuncanAndrew N Macintyre

clinical microbiologyepidemiologydiagnostic microbiologymultiplex assaysclinical epidemiologyinfectious diseasesemerging infectious diseases

Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 From Multidrug-Resistant Neisseria Gonorrhoeae H041. ACS Infectious Diseases (2024)

Jonathan M. TurnerCaleb M. StrattonSandeepchowdary BalaMaria Cardenas AlvarezRobert A. NicholasChristopher Davies

medicineantimicrobial resistancepharmacologyantibiotic resistancedisease transmissioninfection controlvenereologyclinical infectionclinical microbiologyapplied microbiologyveterinary medicinepotent inhibitorsdrug resistancevirologypathogenic bacteriainfectious diseasesclinical infectious diseaseemerging infectious diseases

Commensal Neisseria Species Share Immune Suppressive Mechanisms With Neisseria Gonorrhoeae. PLoS ONE (2023)

Weiyan ZhuMaria X. Cardenas-AlvarezJoshua TombergMarguerite B. LittleJoseph A. DuncanRobert A. Nicholas

immunologymicrobial pathogenesisepidemiologyneisseria gonorrhoeaerespiratory medicineinfectious diseases

Commentary on ‘Identification and Characterization of Select Oxysterols as Ligands for Gpr17’. British Journal of Pharmacology (2023)

Robert A. Nicholas

medicinal chemistrypharmacologyselect oxysterolsoxysteroltranslational pharmacologypharmacotherapymolecular pharmacologytherapeutic targetsbiomolecular engineeringapplied pharmacologydrug discoverymedicinal researchexperimental pharmacologypharmacological studiesclinical pharmacologypharmacological researchbiochemistry

Loss of P2Y1 Receptor Desensitization Does Not Impact Hemostasis or Thrombosis Despite Increased Platelet Reactivity in Vitro. Journal of Thrombosis and Haemostasis (2023)

David S. PaulTasha N. BlattWyatt J. SchugEmily G. ClarkTomohiro KawanoNigel MackmanSebastian MurciaKathryn O. PoeJean Marie N. MwizaT. Kendall HardenWolfgang BergmeierRobert A. Nicholas

immunologycardiologyreceptorspharmacologyhematologythrombosisnephrologyhemostasis

Mutational Analysis of Ltgc, a Lytic Transglycosylase Required for Cell Separation in Neisseria Gonorrhoeae. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ryan E. SchaubKrizia Perez-MedinaJoshua TombergRobert A. NicholasJoseph P. Dillard

mutational analysismicrobial pathogenesismolecular microbiologyclinical microbiologymicrobial geneticsenzymesmolecular biologyinfectious diseasespathologylytic transglycosylasecell separation

Preclinical Safety and Efficacy Characterization of an Lpxc Inhibitor Against Gram-Negative Pathogens. Science Translational Medicine (2023)

Jinshi ZhaoC. Skyler CochraneJavaria NajeebDavid GoodenCarly SciandraPing FanNadine LemaitreKate NewnsRobert A. NicholasZiqiang GuanJoshua T. ThadenVance G. FowlerIvan SpasojevicFlorent SebbaneEric J. TooneClayton DuncanRichard GammansPei Zhou

medicinepharmacologygram-negative pathogenslpxc inhibitorefficacy characterizationpreclinical safetyinfectious diseasestranslational medicine

Developing Evidence-Based Resources for Evaluating Postgraduate Trainees in the Biomedical Sciences. PLoS ONE (2022)

Jacqueline E. McLaughlinRebekah L. LaytonPaul B. WatkinsRobert A. NicholasKim L. R. Brouwer

postgraduate traineesbiomedical sciencesevidence-based resources

Draft Genome Sequences of Three Penicillin-Resistant Neisseria Gonorrhoeae Strains Isolated in Cincinnati, Ohio, in 1994. Microbiology Resource Announcements (2021)

Thomas C. MurphyTatum D. MortimerRobert A. NicholasCrista B. Wadsworth

genomicspenicillin-resistant neisseriadraft genome sequencesclinical microbiologyinfectious diseasesmedical microbiologyveterinary microbiologymicrobiology

Molecular Features of Cephalosporins Important for Activity Against Antimicrobial-Resistant Neisseria Gonorrhoeae. ACS Infectious Diseases (2021)

Jonathan M. TurnerKristie L. ConnollyKate E. AbermanJoseph C. FonsecaAvinash SinghAnn E. JerseRobert A. NicholasChristopher Davies

antimicrobial agentsantimicrobial resistancepharmacologymicrobial pathogenesisinfection controlmolecular microbiologyclinical infectionclinical microbiologymolecular featuresantimicrobial susceptibilitydrug resistancevirologymolecular biologyinfectious diseasesveterinary microbiologymolecular medicineemerging infectious diseases

1
2
3
4
5
14
10 / page

Robert Nicholas

Professor & Vice Chair for Research and Education

University of North Carolina at Chapel Hill

Affiliations

School of Medicine

Pharmacology

Robert Nicholas is currently serving as a Pharmacology Professor & Vice Chair for Research and Education at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Robert Nicholas

University of North Carolina at Chapel Hill

Professor & Vice Chair for Research and Education

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Development and Validation of Multiplex Assays for Mouse and Human Igg and Iga to Neisseria Gonorrhoeae Antigens. The Journal of Infectious Diseases (2024)

Erica L StoverMarguerite B LittleKristie L ConnollyLixin LiRobert A NicholasAleksandra E SikoraAnn E JerseMarcia M HobbsJ Alex DuncanAndrew N Macintyre

clinical microbiologyepidemiologydiagnostic microbiologymultiplex assaysclinical epidemiologyinfectious diseasesemerging infectious diseases

Ureidopenicillins Are Potent Inhibitors of Penicillin-Binding Protein 2 From Multidrug-Resistant Neisseria Gonorrhoeae H041. ACS Infectious Diseases (2024)

Jonathan M. TurnerCaleb M. StrattonSandeepchowdary BalaMaria Cardenas AlvarezRobert A. NicholasChristopher Davies

Commensal Neisseria Species Share Immune Suppressive Mechanisms With Neisseria Gonorrhoeae. PLoS ONE (2023)

Weiyan ZhuMaria X. Cardenas-AlvarezJoshua TombergMarguerite B. LittleJoseph A. DuncanRobert A. Nicholas

immunologymicrobial pathogenesisepidemiologyneisseria gonorrhoeaerespiratory medicineinfectious diseases

Commentary on ‘Identification and Characterization of Select Oxysterols as Ligands for Gpr17’. British Journal of Pharmacology (2023)

Robert A. Nicholas

Loss of P2Y1 Receptor Desensitization Does Not Impact Hemostasis or Thrombosis Despite Increased Platelet Reactivity in Vitro. Journal of Thrombosis and Haemostasis (2023)

David S. PaulTasha N. BlattWyatt J. SchugEmily G. ClarkTomohiro KawanoNigel MackmanSebastian MurciaKathryn O. PoeJean Marie N. MwizaT. Kendall HardenWolfgang BergmeierRobert A. Nicholas

immunologycardiologyreceptorspharmacologyhematologythrombosisnephrologyhemostasis

Mutational Analysis of Ltgc, a Lytic Transglycosylase Required for Cell Separation in Neisseria Gonorrhoeae. bioRxiv (Cold Spring Harbor Laboratory) (2023)

Ryan E. SchaubKrizia Perez-MedinaJoshua TombergRobert A. NicholasJoseph P. Dillard

mutational analysismicrobial pathogenesismolecular microbiologyclinical microbiologymicrobial geneticsenzymesmolecular biologyinfectious diseasespathologylytic transglycosylasecell separation

Preclinical Safety and Efficacy Characterization of an Lpxc Inhibitor Against Gram-Negative Pathogens. Science Translational Medicine (2023)

medicinepharmacologygram-negative pathogenslpxc inhibitorefficacy characterizationpreclinical safetyinfectious diseasestranslational medicine

Developing Evidence-Based Resources for Evaluating Postgraduate Trainees in the Biomedical Sciences. PLoS ONE (2022)

Jacqueline E. McLaughlinRebekah L. LaytonPaul B. WatkinsRobert A. NicholasKim L. R. Brouwer

postgraduate traineesbiomedical sciencesevidence-based resources

Draft Genome Sequences of Three Penicillin-Resistant Neisseria Gonorrhoeae Strains Isolated in Cincinnati, Ohio, in 1994. Microbiology Resource Announcements (2021)

Thomas C. MurphyTatum D. MortimerRobert A. NicholasCrista B. Wadsworth

genomicspenicillin-resistant neisseriadraft genome sequencesclinical microbiologyinfectious diseasesmedical microbiologyveterinary microbiologymicrobiology

Molecular Features of Cephalosporins Important for Activity Against Antimicrobial-Resistant Neisseria Gonorrhoeae. ACS Infectious Diseases (2021)

Jonathan M. TurnerKristie L. ConnollyKate E. AbermanJoseph C. FonsecaAvinash SinghAnn E. JerseRobert A. NicholasChristopher Davies

1
2
3
4
5
14
10 / page

Similar Faculty Members

Tina Iverson

Institution

Vanderbilt University

structural biology

covid

Matthew Redinbo

Institution

University of North Carolina at Chapel Hill

gut microbial pathogens

microbiology

Mark Donowitz

Institution

Johns Hopkins University

pharmacology

gastroenterology

Suzanne Walker

Institution

Harvard University

molecular metabolism

drug resistance analysis

Eric Skaar

Institution

Vanderbilt University

emerging infectious disease

acinetobacter baumannii

Anthony E. Pegg

Institution

Pennsylvania State University

cancer letter

toxicological mechanism

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics

Phillip Hylemon

Institution

Virginia Commonwealth University

digestive tract

dysbiosis

Robert A. Bonomo

Institution

Case Western Reserve University

biomolecular structure

protein structure

Shahriar Mobashery

Institution

University of Notre Dame

pharmacology

biochemistry

Similar Faculty Members

Tina Iverson

Institution

Vanderbilt University

structural biology

covid

Matthew Redinbo

Institution

University of North Carolina at Chapel Hill

gut microbial pathogens

microbiology

Mark Donowitz

Institution

Johns Hopkins University

pharmacology

gastroenterology

Suzanne Walker

Institution

Harvard University

molecular metabolism

drug resistance analysis

Eric Skaar

Institution

Vanderbilt University

emerging infectious disease

acinetobacter baumannii

Anthony E. Pegg

Institution

Pennsylvania State University

cancer letter

toxicological mechanism

Walter Chazin

Institution

Vanderbilt University

molecular biology

proteomics

Phillip Hylemon

Institution

Virginia Commonwealth University

digestive tract

dysbiosis

Robert A. Bonomo

Institution

Case Western Reserve University

biomolecular structure

protein structure

Shahriar Mobashery

Institution

University of Notre Dame

pharmacology

biochemistry