Faculty

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Unit

Venue

Richard Neubig

Professor Emeritus and Director Drug Discovery Program

Michigan State University

Affiliations

College of Human Medicine

Department of Pharmacology and Toxicology

Richard Neubig is currently serving as a College Of Human Medicine Professor Emeritus and Director Drug Discovery Program at Michigan State University.

Honors

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Experiences

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Education

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Richard Neubig

Michigan State University

Professor Emeritus and Director Drug Discovery Program

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pharmacology molecular biology cell signaling neuroscience receptors signal transduction protein science biochemistry medicinal research molecular pharmacology gene expression g protein-coupled receptor drug discovery structural biology enzyme inhibition mammalian biology medicinal chemistry biological chemistry molecular physiology receptor (biochemistry) pharmacotherapy signaling pathways molecular regulation cardiovascular research clinical pharmacology cancer biology pharmacological research melanoma molecular cancer cancer genomics vascular biology peptides cell regulation pharmacokinetics gene regulation cellular physiology respiratory medicine high-throughput screening rgs proteins experimental pharmacology pathway analysis protein function international union redox biology experimental medicine tumor targeting neurochemistry cancer genetics functional modification drug targeting molecular neurobiology fibrosis rational drug design biomolecular interactions pharmaceutical sciences hemostasis transcription regulation anti-cancer agents cardiovascular physiology endogenous rgs proteins g-protein signaling protein bioinformatics cell physiology pharmaceutical chemistry dry motif small-molecule inhibitors rapid kinetics human platelets adenylate cyclase membrane organization murine model antagonist binding inverse agonist activity agouti-related protein prostate cancer cells g-protein signaling proteins systems biology molecular cell biology biological function cell biology

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Aav9-Mediated Intra-Striatal Delivery of Gnao1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant Mice. Journal of Pharmacology and Experimental Therapeutics (2024)

Alex J. RoyJeffrey R. LeipprandtJoseph R. PattersonAnna C. StollChristopher J. KempZaipo-Tcheisian D. OulaTyler MolaAna R. BatistaCaryl E. SortwellMiguel Sena-EstevesRichard R. Neubig

gene therapygene expressionpharmacologyavian biologypharmacokineticsneurogeneticsgene deliverygene vectorgeneticsmammalian biologygene transfergenomic mechanismsanimal biotechnologymolecular biologymolecular geneticsdrug deliveryexperimental medicinepharmaceutics

Development of an Srf Inhibitor Peptide for the Treatment of Cardiac Fibrosis. Spartan Medical Research Journal (2024)

Melissa HerschkowitzErika LisabethRichard Neubig

medicinebiomedical researchpeptidesfibrosisclinical researchmedicinal researchcardiac fibrosissrf inhibitor peptide

Development of a Srf Inhibitor Peptide for the Treatment of Cardiac Fibrosis. Journal of Pharmacology and Experimental Therapeutics (2024)

Melissa MeschkewitzErika M. LisabethRichard R. Neubig

cardiologyenzyme inhibitionpharmacologypeptidesbiomarker targetpeptide engineeringmolecular engineeringpeptide scienceenzyme specificitycardiac fibrosistherapeutic targetsmolecular biologymedicinal researchtherapeutic efficacyprotein engineeringsrf inhibitor peptidebiochemistryinflammation

Inhibition of the Rho / Mrtf Pathway Improves the Response of Braf ‐Resistant Melanoma to Pd1 / Pdl1 Blockade. International Journal of Cancer (2024)

Bardees M. FodaSean A. MisekKathleen A. GalloRichard R. Neubig

dermatologyleukemiamelanomaradiation oncologycancer researchtumor suppressorscancer immunotherapycancer imagingoncologyclinical researchmedicinal researchcancer treatmentcancer biologyskin cancertumor biologyhealth sciences

Mechanistic Insights Into Rho/Mrtf Inhibition-Induced Apoptotic Events and Prevention of Drug Resistance in Melanoma: Implications for the Involvement of Pirin. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Bardees M. FodaAnnika E. BakerŁukasz JoachimiakMarzena MazurRichard R. Neubig

pharmacologymelanomacancer researchsystems biologydrug resistancemechanistic insightsmolecular biologyoncologycancer cellstumor biologycancer prevention

Pirin Does Not Bind to P65 or Regulate Nfkappab-Dependent Gene Expression. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Melissa MeschkewitzErika M LisabethA. Denaly Cab-GomezJeffrey LeipprandtRichard R Neubig

gene expressiontranscription regulationgene regulatory networksgeneticstranscription factorsbiologynfkappab-dependent gene expressionmolecular biologyoncogenescancer biologygene regulation

Class a Orphans in Gtopdb V.2023.1. IUPHAR/BPS Guide to Pharmacology CITE (2023)

Stephen P.H. AlexanderJim BatteyHelen E. BensonRichard V. BenyaTom I. BonnerAnthony P. DavenportKhuraijam Dhanachandra SinghSatoru EguchiAnthony HarmarNick HollidayRobert T. JensenSadashiva KarnikEvi KostenisWen Chiy LiewAmy E. MonaghanChido MpamhangaRichard NeubigAdam J PawsonJean-Philippe PinJoanna L. SharmanMichael SpeddingEliot SpindelLeigh StoddartLaura StorjohannWalter G. ThomasKalyan TirupulaPatrick Vanderheyden

pharmacology

Contributions of Atp12A, a Non-Gastric Proton Pump Alpha Subunit, to the Pathogenesis of Idiopathic Pulmonary Fibrosis. Physiology (2023)

Xiaopeng LiMohamed AbdelgiedKatie UhlOliver ChenChad SchultzKaylie TrippAngela PerainoShreya PaithankarBin ChenMaximiliano Tamae KakazuAlicia Castillo BahenaTara JagerCameron LawsonDave CheslaNikolay PestovNikolai ModyanovJeremy ProkopRichard NeubigBruce UhalReda Girgis

physiologyrespiration (physiology)veterinary medicineidiopathic pulmonary fibrosisrespiratory medicinedisease physiologypathologyhealth sciences

Development and Validation of a High-Throughput Cell-Based Alphalisa Assay to Identify Small Molecule 20S Proteasome Modulators. Journal of Pharmacology and Experimental Therapeutics (2023)

Erika LisabethSophia StaerzEvert NjomenThomas DexheimerRichard NeubigJetze Tepe

proteomicssmall moleculeshigh-throughput cell-based alphalisabiomolecular engineeringproteasome modulators

Development of a Cell-Based Alphalisa Assay for High-Throughput Screening for Small Molecule Proteasome Modulators. ACS Omega (2023)

Sophia D. StaerzErika M. LisabethEvert NjomenThomas S. DexheimerRichard R. NeubigJetze J. Tepe

proteomicshigh-throughput screeningbiomolecular engineeringcell-based alphalisa assayanalytical biotechnologycell biology

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Richard Neubig

Professor Emeritus and Director Drug Discovery Program

Michigan State University

Affiliations

College of Human Medicine

Department of Pharmacology and Toxicology

Richard Neubig is currently serving as a College Of Human Medicine Professor Emeritus and Director Drug Discovery Program at Michigan State University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Richard Neubig

Michigan State University

Professor Emeritus and Director Drug Discovery Program

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Aav9-Mediated Intra-Striatal Delivery of Gnao1 Reduces Hyperlocomotion in Gnao1 Heterozygous R209H Mutant Mice. Journal of Pharmacology and Experimental Therapeutics (2024)

Alex J. RoyJeffrey R. LeipprandtJoseph R. PattersonAnna C. StollChristopher J. KempZaipo-Tcheisian D. OulaTyler MolaAna R. BatistaCaryl E. SortwellMiguel Sena-EstevesRichard R. Neubig

Development of an Srf Inhibitor Peptide for the Treatment of Cardiac Fibrosis. Spartan Medical Research Journal (2024)

Melissa HerschkowitzErika LisabethRichard Neubig

medicinebiomedical researchpeptidesfibrosisclinical researchmedicinal researchcardiac fibrosissrf inhibitor peptide

Development of a Srf Inhibitor Peptide for the Treatment of Cardiac Fibrosis. Journal of Pharmacology and Experimental Therapeutics (2024)

Melissa MeschkewitzErika M. LisabethRichard R. Neubig

Inhibition of the Rho / Mrtf Pathway Improves the Response of Braf ‐Resistant Melanoma to Pd1 / Pdl1 Blockade. International Journal of Cancer (2024)

Bardees M. FodaSean A. MisekKathleen A. GalloRichard R. Neubig

Bardees M. FodaAnnika E. BakerŁukasz JoachimiakMarzena MazurRichard R. Neubig

pharmacologymelanomacancer researchsystems biologydrug resistancemechanistic insightsmolecular biologyoncologycancer cellstumor biologycancer prevention

Pirin Does Not Bind to P65 or Regulate Nfkappab-Dependent Gene Expression. bioRxiv (Cold Spring Harbor Laboratory) (2024)

Melissa MeschkewitzErika M LisabethA. Denaly Cab-GomezJeffrey LeipprandtRichard R Neubig

gene expressiontranscription regulationgene regulatory networksgeneticstranscription factorsbiologynfkappab-dependent gene expressionmolecular biologyoncogenescancer biologygene regulation

Class a Orphans in Gtopdb V.2023.1. IUPHAR/BPS Guide to Pharmacology CITE (2023)

pharmacology

Contributions of Atp12A, a Non-Gastric Proton Pump Alpha Subunit, to the Pathogenesis of Idiopathic Pulmonary Fibrosis. Physiology (2023)

physiologyrespiration (physiology)veterinary medicineidiopathic pulmonary fibrosisrespiratory medicinedisease physiologypathologyhealth sciences

Development and Validation of a High-Throughput Cell-Based Alphalisa Assay to Identify Small Molecule 20S Proteasome Modulators. Journal of Pharmacology and Experimental Therapeutics (2023)

Erika LisabethSophia StaerzEvert NjomenThomas DexheimerRichard NeubigJetze Tepe

proteomicssmall moleculeshigh-throughput cell-based alphalisabiomolecular engineeringproteasome modulators

Development of a Cell-Based Alphalisa Assay for High-Throughput Screening for Small Molecule Proteasome Modulators. ACS Omega (2023)

Sophia D. StaerzErika M. LisabethEvert NjomenThomas S. DexheimerRichard R. NeubigJetze J. Tepe

proteomicshigh-throughput screeningbiomolecular engineeringcell-based alphalisa assayanalytical biotechnologycell biology

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