Faculty

Institution

Unit

Venue

Daniel TS Pak

Professor

Georgetown University

Affiliations

School of Medicine

Pharmacology & Physiology

Daniel Ts Pak is currently serving as a Pharmacology & Physiology Professor at Georgetown University.

Honors

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Experiences

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Education

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Daniel TS Pak

Georgetown University

Professor

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neuroscience neurology systems neuroscience neurophysiology cognitive neuroscience alzheimer's disease molecular neurobiology pharmacology molecular neuroscience neurochemistry cellular neurobiology neural science genetics brain science neuroanatomy cell signaling signal transduction protein science dendritic spine density mammalian biology homeostatic synaptic plasticity amyloid precursor protein cellular physiology insect molecular biology biochemical sciences brain function synaptic plasticity mouse model benzothiazole aniline oncogenes molecular physiology molecular neurodegeneration molecular cell biology cytogenetics signaling pathways neurotransmission protein phosphorylation cell trafficking protein transport spinal biomechanics yeast cellular biology biomolecular interactions excitatory synapses dendritic spines homeostatic plasticity dendritic spine formation avian biology genome biology general virology virus research animal physiology neurorehabilitation enzyme inhibition transcription regulation epigenomics protein genetics candidate selection antibody engineering hemostasis clinical neuroscience viral replication viral genetics neurodynamics knockout mice stem cell trafficking intracellular trafficking conformational studies disease mechanisms functional modification higher eukaryotes origin recognition complex dendritic spine morphology signaling proteins synapse remodeling protein degradation structural plasticity molecular changes molecular biology synapse number synaptic protein composition cellular biochemistry

Notable Scholarly Works

Notable Federal Grants

Collaborators

Amyloid Precursor Protein Combinatorial Phosphorylation Code Regulates Ampa Receptor Removal During Distinct Forms of Synaptic Plasticity. Biochemical and Biophysical Research Communications (2024)

Jisoo LeeDaniel T.S. Pak

biophysicsalzheimer's diseaseneurochemistrysystems neuroscienceprotein sciencemolecular neurobiologyneurosciencebiochemistryneurodegenerative diseasesampa receptor removalmolecular neurosciencesynaptic plasticityamyloid precursor

Mass Spectrometry Identifies Tau C‐Terminal Phosphorylation Cluster During Neuronal Hyperexcitation. Journal of Neurochemistry (2024)

Amanda SchneeweisDawson HillyerTsering LamaDaeun KimCharles PalkaSarra DjemilMai Abdel‐GhaniKelly MandellaWilliam ZhuNicole AlvarezLara StefanssonRobert YasudaJunfeng MaDaniel T.S. Pak

neurochemistryneuronal hyperexcitationneurosciencec-terminal phosphorylation clustermass spectrometry

Resveratrol Differentially Affects Mmp‐9 Release From Neurons and Glia; Implications for Therapeutic Efficacy. Journal of Neurochemistry (2024)

Matthew AmontreeMatthew NelsonLara StefanssonDaniel PakKathleen Maguire‐ZeissR. Scott TurnerKatherine Conant

neurologyneural sciencealzheimer's diseaseneurochemistryneuroprotectionneuropharmacologycellular neurobiologyneuronsneuroscienceneuroinflammationneurophysiologypharmacologyreceptors

Mass Spectrometry Identifies Tau C‐Terminal Phosphorylation Signature of Neuronal Hyperexcitation. Alzheimer's & dementia (2023)

Amanda SchneeweisTsering LamaJunfeng MaDaniel T.S. Pak

neurologyalzheimer's diseaseneuronal hyperexcitationneurosciencemass spectrometry

Plk2 Promotes Synaptic Destabilization Through Disruption of N‐Cadherin Adhesion Complexes During Homeostatic Adaptation to Hyperexcitation. Journal of Neurochemistry (2023)

Mai Abdel‐GhaniYeunkum LeeLyna Ait AkliMarielena MoranAmanda SchneeweisSarra DjemilRebecca El ChoueiryRuqaya MurtadhaDaniel T. S. Pak

neurologyneurochemistrysystems neuroscienceneurosciencehomeostatic adaptationn-cadherin adhesion complexesmolecular neurosciencesynaptic destabilization

The Human Acetylcholinesterase C-Terminal T30 Peptide Activates Neuronal Growth Through Alpha 7 Nicotinic Acetylcholine Receptors and the Mtor Pathway. Scientific Reports (2023)

Alexandru GraurPatricia SinclairAmanda K. SchneeweisDaniel T. PakNadine Kabbani

neurologyneurochemistrymtor pathwayneuropharmacologycell signalingneuroscienceneurotransmissionpeptidesnicotinic acetylcholine receptorsneuronal growthpharmacologysignal transductioncentral nervous system

Wherefore Art Tau? Functional Importance of Site-Specific Tau Phosphorylation in Diverse Subcellular Domains. The International Journal of Biochemistry & Cell Biology (2023)

Amanda SchneeweisDaniel T.S. Pak

molecular and cellular biologyneurosciencecellular biologybiomolecular interactionscell and molecular biologycell biologysite-specific tau phosphorylationprotein foldingcell biophysicscellular biochemistrytheoretical biologyprotein functioncellular physiologybiochemistrymolecular basisstructural biologyart taumembrane biologymolecular cell biologybiochemical sciencesdiverse subcellular domains

Ach Transfers: Homeostatic Plasticity of Cholinergic Synapses. Cellular and Molecular Neurobiology (2022)

Sarra DjemilAntonia M. SamesDaniel T. S. Pak

neurochemistryach transferssystems neuroscienceneuroanatomycellular neurobiologymolecular neurobiologyneurosciencehomeostatic plasticitymolecular neurosciencecholinergic synapses

66108 Central Cholinergic Synapse Formation in Optimized Primary Septal “Hippocampal Co” Cultures. Journal of Clinical and Translational Science (2021)

Sarra DjemilClaire R. ResselAmanda K. SchneeweisiS. Abdel-GhaniDaniel T.S. Pak

neurologyneural scienceneurochemistrysystems neurosciencetranslational medicinecellular neurobiologybrain organizationneurosciencemembrane biologymedicineexperimental medicinetranslational physiologyclinical researchcentral nervous system

4303 Optimization of Primary Septal-Hippocampal Co-Cultures to Study Central Cholinergic Synapse Formation and Dysfunction. Journal of Clinical and Translational Science (2020)

Sarra DjemilClaire R. ResselDaniel T.S. Pak

neurologyneural scienceneurochemistrysystems neurosciencecellular neurobiologycognitive neuroscienceneurosciencemolecular neurobiologyprimary septal-hippocampal co-culturesmembrane biologymedicineclinical researchcomputational neurosciencebrain function

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Daniel TS Pak

Professor

Georgetown University

Affiliations

School of Medicine

Pharmacology & Physiology

Daniel Ts Pak is currently serving as a Pharmacology & Physiology Professor at Georgetown University.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Daniel TS Pak

Georgetown University

Professor

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Amyloid Precursor Protein Combinatorial Phosphorylation Code Regulates Ampa Receptor Removal During Distinct Forms of Synaptic Plasticity. Biochemical and Biophysical Research Communications (2024)

Jisoo LeeDaniel T.S. Pak

Mass Spectrometry Identifies Tau C‐Terminal Phosphorylation Cluster During Neuronal Hyperexcitation. Journal of Neurochemistry (2024)

Amanda SchneeweisDawson HillyerTsering LamaDaeun KimCharles PalkaSarra DjemilMai Abdel‐GhaniKelly MandellaWilliam ZhuNicole AlvarezLara StefanssonRobert YasudaJunfeng MaDaniel T.S. Pak

neurochemistryneuronal hyperexcitationneurosciencec-terminal phosphorylation clustermass spectrometry

Resveratrol Differentially Affects Mmp‐9 Release From Neurons and Glia; Implications for Therapeutic Efficacy. Journal of Neurochemistry (2024)

Matthew AmontreeMatthew NelsonLara StefanssonDaniel PakKathleen Maguire‐ZeissR. Scott TurnerKatherine Conant

neurologyneural sciencealzheimer's diseaseneurochemistryneuroprotectionneuropharmacologycellular neurobiologyneuronsneuroscienceneuroinflammationneurophysiologypharmacologyreceptors

Mass Spectrometry Identifies Tau C‐Terminal Phosphorylation Signature of Neuronal Hyperexcitation. Alzheimer's & dementia (2023)

Amanda SchneeweisTsering LamaJunfeng MaDaniel T.S. Pak

neurologyalzheimer's diseaseneuronal hyperexcitationneurosciencemass spectrometry

Plk2 Promotes Synaptic Destabilization Through Disruption of N‐Cadherin Adhesion Complexes During Homeostatic Adaptation to Hyperexcitation. Journal of Neurochemistry (2023)

Mai Abdel‐GhaniYeunkum LeeLyna Ait AkliMarielena MoranAmanda SchneeweisSarra DjemilRebecca El ChoueiryRuqaya MurtadhaDaniel T. S. Pak

neurologyneurochemistrysystems neuroscienceneurosciencehomeostatic adaptationn-cadherin adhesion complexesmolecular neurosciencesynaptic destabilization

The Human Acetylcholinesterase C-Terminal T30 Peptide Activates Neuronal Growth Through Alpha 7 Nicotinic Acetylcholine Receptors and the Mtor Pathway. Scientific Reports (2023)

Alexandru GraurPatricia SinclairAmanda K. SchneeweisDaniel T. PakNadine Kabbani

Wherefore Art Tau? Functional Importance of Site-Specific Tau Phosphorylation in Diverse Subcellular Domains. The International Journal of Biochemistry & Cell Biology (2023)

Amanda SchneeweisDaniel T.S. Pak

Ach Transfers: Homeostatic Plasticity of Cholinergic Synapses. Cellular and Molecular Neurobiology (2022)

Sarra DjemilAntonia M. SamesDaniel T. S. Pak

neurochemistryach transferssystems neuroscienceneuroanatomycellular neurobiologymolecular neurobiologyneurosciencehomeostatic plasticitymolecular neurosciencecholinergic synapses

66108 Central Cholinergic Synapse Formation in Optimized Primary Septal “Hippocampal Co” Cultures. Journal of Clinical and Translational Science (2021)

Sarra DjemilClaire R. ResselAmanda K. SchneeweisiS. Abdel-GhaniDaniel T.S. Pak

4303 Optimization of Primary Septal-Hippocampal Co-Cultures to Study Central Cholinergic Synapse Formation and Dysfunction. Journal of Clinical and Translational Science (2020)

Sarra DjemilClaire R. ResselDaniel T.S. Pak

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