Faculty

Institution

Unit

Venue

Nitin Pandey

Assistant Professor of Research Physiology and Neuroscience

University of Southern California

Affiliations

Keck School of Medicine

Physiology and Neuroscience

Nitin Pandey is currently serving as a Keck School Of Medicine Assistant Professor of Research Physiology and Neuroscience at University of Southern California.

Honors

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Experiences

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Education

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Nitin Pandey

University of Southern California

Assistant Professor of Research Physiology and Neuroscience

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structural biology molecular biology protein science biochemistry biophysics neuroscience protein structure membrane biology molecular biophysics enzymes structural molecular biology macromolecular science human serum albumin biochemical sciences biological chemistry biomolecular structure biological inorganic chemistry drug discovery protein folding clinical biochemistry biological macromolecules inorganic chemistry molecular physiology coordination chemistry molecular science biomolecular interactions integrative biology protein function macromolecular chemistry macromolecular systems protein chemistry protein assembly medical biophysics fragmentation effect photobiology bovine serum albumin plo biology nutritional biochemistry genome biology drug analysis pharmaceutics laboratory medicine protein transport molecular regulation molecular evidence conformational studies mutagenesis spectroscopic property spectroscopic methods molecular biotechnology molecular docking molecular research neurochemistry high-throughput screening molecular neurobiology pharmaceutical technology pharmaceutical sciences pharmaceutical research pharmaceutical chemistry clinical pharmacology bioactive metal trace metals different mechanisms prolonged glycation different toxicity huntingtin fibrils polyglutamine tract aggregation mechanisms membrane-bound huntingtin mutant huntingtin fibril assemblies distinct conformations preformed fibrils preferential binding docking studies native state protein structure prediction

Notable Scholarly Works

Notable Federal Grants

Collaborators

Developing Rapport Between Humans and Machines: Emotionally Intelligent AI Assistants. International journal for research in applied science and engineering technology (2024)

Raj AgrawalNakul Pandey

communicationemotional intelligencehuman-computer interactionuser experiencehuman-machine interactionhuman behaviorhuman-ai interactionartificial intelligenceuser interfacesmanmachine interactionhuman agent interactioncognitive sciencemachine learninghuman robot interactionbehavioral sciences

Tdp43 and Huntingtin Exon-1 Undergo a Conformationally Specific Interaction That Strongly Alters the Fibril Formation of Both Proteins. Journal of Biological Chemistry (2024)

Gincy GeorgeAnakha AjayanJobin VarkeyNitin K PandeyJeannie ChenRalf Langen

specific interactionbiological macromoleculesprotein functionprotein structurebiological chemistrybiochemistrybiomolecular interactionsmolecular cell biologystructural biologyfibril formationprotein scienceprotein foldingprotein assemblyprotein misfoldingmolecular and cellular biologyprotein phosphorylationbiophysicsmolecular biologystructural molecular biology

Fluorescent Protein Tagging Promotes Phase Separation and Alters the Aggregation Pathway of Huntingtin Exon-1. Journal of Biological Chemistry (2023)

Nitin K. PandeyJobin VarkeyAnakha AjayanGincy GeorgeJeannie ChenRalf Langen

aggregation pathwaymolecular biologycell biologyneurosciencebioinformatics

Amplification of Neurotoxic Httex1 Assemblies in Human Neurons. Neurobiology of Disease (2021)

Anjalika ChongthamJ. Mario IsasNitin K. PandeyAnoop RawatJung Hyun YooTara MastroMary B. KennedyRalf LangenAli Khoshnan

human neuronsneurologyneuroscienceneurons

Huntingtin Fibrils With Different Toxicity, Structure, and Seeding Potential Can Be Interconverted. Nature Communications (2021)

J Mario IsasNK PandeyH XuK TeranishiAK OkadaEK FultzA Rawat...

biophysicsprotein structuredifferent toxicityhuntingtin fibrilsstructural biologyneuroscience

Sonicated Fibrils of Huntingtin Exon-1 Preferentially Seed Neurons and Produce Toxic Assemblies. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Anjalika ChongthamJ Mario IsasNitin K PandeyAnoop RawatJung Hyun YooTara MastroMarry KennedyRalf LangenAli Khoshnan

neurologytoxic assembliesdevelopmental neurobiologydevelopmental biologyfibrinolysisneuroscience

Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by Fret-Based High-Throughput Screening in Living Cells. ACS Chemical Neuroscience (2020)

Chih Hung LoNitin K. PandeyColin Kin-Wye LimZhipeng DingMeixin TaoDavid D. ThomasRalf LangenJonathan N. Sachs

medicinal chemistryfret-based high-throughput screeningpharmacologyproteomicshigh-throughput screeningliving cellsneurochemistrymolecular neurobiologyneuropharmacologysmall molecule inhibitorsdrug discoveryneurosciencebioinformaticscell biology

Lipid-Modulation of Membrane Insertion and Refolding of the Apoptotic Inhibitor Bcl-XL. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics (2019)

Victor Vasquez-MontesMauricio Vargas-UribeNitin K. PandeyMykola V. RodninRalf LangenAlexey S. Ladokhin

apoptotic inhibitor bcl-xlbiophysicsproteomicspharmacologycell deathapoptosismembrane insertionmolecular biologystructural biologyprotein sciencemembrane biology

Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms. Structure (2019)

Meixin TaoNitin K. PandeyRyan BarnesSongi HanRalf Langen

biophysicsprotein structuremolecular biologymembrane-bound huntingtinstructural biologyneuroscienceaggregation mechanisms

Identification of Distinct Conformations Associated With Monomers and Fibril Assemblies of Mutant Huntingtin. Human Molecular Genetics (2018)

Jan KoJ Mario IsasAdam SabbaughJung Hyun YooNitin K PandeyAnjalika ChongthamMark LadinskyWei-Li WuHeike RohwederAndreas WeissDouglas MacdonaldIgnacio Munoz-SanjuanRalf LangenPaul H PattersonAli Khoshnan

protein assemblyprotein chemistrymutagenesisprotein structuregeneticsfibril assembliesmutant huntingtinconformational studiesmolecular geneticsmolecular biologystructural biologyprotein sciencehuman geneticsbiochemistrydistinct conformations

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Nitin Pandey

Assistant Professor of Research Physiology and Neuroscience

University of Southern California

Affiliations

Keck School of Medicine

Physiology and Neuroscience

Nitin Pandey is currently serving as a Keck School Of Medicine Assistant Professor of Research Physiology and Neuroscience at University of Southern California.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Nitin Pandey

University of Southern California

Assistant Professor of Research Physiology and Neuroscience

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

Developing Rapport Between Humans and Machines: Emotionally Intelligent AI Assistants. International journal for research in applied science and engineering technology (2024)

Raj AgrawalNakul Pandey

Tdp43 and Huntingtin Exon-1 Undergo a Conformationally Specific Interaction That Strongly Alters the Fibril Formation of Both Proteins. Journal of Biological Chemistry (2024)

Gincy GeorgeAnakha AjayanJobin VarkeyNitin K PandeyJeannie ChenRalf Langen

Fluorescent Protein Tagging Promotes Phase Separation and Alters the Aggregation Pathway of Huntingtin Exon-1. Journal of Biological Chemistry (2023)

Nitin K. PandeyJobin VarkeyAnakha AjayanGincy GeorgeJeannie ChenRalf Langen

aggregation pathwaymolecular biologycell biologyneurosciencebioinformatics

Amplification of Neurotoxic Httex1 Assemblies in Human Neurons. Neurobiology of Disease (2021)

Anjalika ChongthamJ. Mario IsasNitin K. PandeyAnoop RawatJung Hyun YooTara MastroMary B. KennedyRalf LangenAli Khoshnan

human neuronsneurologyneuroscienceneurons

Huntingtin Fibrils With Different Toxicity, Structure, and Seeding Potential Can Be Interconverted. Nature Communications (2021)

J Mario IsasNK PandeyH XuK TeranishiAK OkadaEK FultzA Rawat...

biophysicsprotein structuredifferent toxicityhuntingtin fibrilsstructural biologyneuroscience

Sonicated Fibrils of Huntingtin Exon-1 Preferentially Seed Neurons and Produce Toxic Assemblies. bioRxiv (Cold Spring Harbor Laboratory) (2021)

Anjalika ChongthamJ Mario IsasNitin K PandeyAnoop RawatJung Hyun YooTara MastroMarry KennedyRalf LangenAli Khoshnan

neurologytoxic assembliesdevelopmental neurobiologydevelopmental biologyfibrinolysisneuroscience

Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by Fret-Based High-Throughput Screening in Living Cells. ACS Chemical Neuroscience (2020)

Chih Hung LoNitin K. PandeyColin Kin-Wye LimZhipeng DingMeixin TaoDavid D. ThomasRalf LangenJonathan N. Sachs

Lipid-Modulation of Membrane Insertion and Refolding of the Apoptotic Inhibitor Bcl-XL. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics (2019)

Victor Vasquez-MontesMauricio Vargas-UribeNitin K. PandeyMykola V. RodninRalf LangenAlexey S. Ladokhin

apoptotic inhibitor bcl-xlbiophysicsproteomicspharmacologycell deathapoptosismembrane insertionmolecular biologystructural biologyprotein sciencemembrane biology

Structure of Membrane-Bound Huntingtin Exon 1 Reveals Membrane Interaction and Aggregation Mechanisms. Structure (2019)

Meixin TaoNitin K. PandeyRyan BarnesSongi HanRalf Langen

biophysicsprotein structuremolecular biologymembrane-bound huntingtinstructural biologyneuroscienceaggregation mechanisms

Identification of Distinct Conformations Associated With Monomers and Fibril Assemblies of Mutant Huntingtin. Human Molecular Genetics (2018)

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4
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cellular motility

molecular biology

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Johns Hopkins University

molecular biology

structural biology

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physical chemistry

molecular biophysics

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molecular metabolism

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infectious diseases

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