Faculty

Institution

Unit

Venue

Mitsuo Yamauchi

Sunstar Distinguished Professor

University of North Carolina at Chapel Hill

Affiliations

Adams School of Dentistry

the Graduate School

Mitsuo Yamauchi is currently serving as an Adams School Of Dentistry Sunstar Distinguished Professor at University of North Carolina At Chapel Hill.

Honors

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Experiences

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Education

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Mitsuo Yamauchi

University of North Carolina at Chapel Hill

Sunstar Distinguished Professor

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dermatology bone research regenerative medicine cell biology structural biology tissue engineering matrix biology biochemistry genetics tissue (biology) oral biology mammalian biology orthopaedic research protein science biochemical sciences membrane biology gene expression oral medicine biomechanics bone metabolism periodontology bone health bone homeostasis vascular biology oral health mechanobiology cancer biology liver physiology redox biology bone density orthopedic biomechanics human tissues biomineralization collagen cross-linking biological chemistry endodontics cutaneous biology skeletal muscle amyotrophic lateral sclerosis fibrosis functional modification clinical dentistry musculoskeletal disorders avian biology histocompatibility dental biomechanics integrative biology musculoskeletal research biogerontology bone disease bone remodeling tissue development tissue physiology connective tissue disease dermal structure tumor stroma fracture healing bone repair protein chemistry musculoskeletal science medical genetics cell-matrix interactions lysine hydroxylation periodontal ligament skeletal unloading bone mass type ia receptor collagen biosynthesis collagen cross-links lysine post-translational modifications apical periodontitis immature dog teeth ultimate tensile strength downstream targets wnt inhibitors differential expression extracellular matrix molecules stem cell research wound healing biomedical engineering functional tissue engineering extracellular matrix bone tissue engineering biomolecular engineering

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Generation of Bone-Specific Lysyl Hydroxylase 2 Knockout Mice and Their Phenotypes. Biochemistry and Biophysics Reports (2024)

Kenta TsuneizumiAtsushi KasamatsuTomoaki SaitoReo FukushimaYuki TagaKazunori MizunoMasataka SunoharaKatsuhiro UzawaMitsuo Yamauchi

biophysicsbiophysical chemistrymolecular biologybiochemistry

Bone Dysplasia in Hutchinson‐Gilford Progeria Syndrome is Associated With Dysregulated Differentiation and Function of Bone Cell Populations. Aging Cell (2023)

Wayne A. CabralChris StephanMasahiko TerajimaAbhirami A. ThaivalappilOwen BlanchardUrraca L. TavarezNarisu NarisuTingfen YanStephen M. WincovitchYuki TagaMitsuo YamauchiKenneth M. KozloffMichael R. ErdosFrancis S. Collins

ageingbone cell populationsdysregulated differentiationdevelopmental biologydermatologybone dysplasiabiogerontology

Collagen Cross‐Linking in Oral Cancer. Oral Science International (2023)

Katsuhiro UzawaAtsushi KasamatsuMitsuo Yamauchi

geneticshealth sciencesoncologyoral biologyoral cancercell biologycollagen cross-linking

Data From Cancer-Associated Fibroblasts Induce a Collagen Cross-Link Switch in Tumor Stroma. (2023)

Daniela PankovaYulong ChenMasahiko TerajimaMark J. SchliekelmanBrandi N. BairdMonica FahrenholtzLi SunBartley J. GillTegy J. VadakkanMin P. KimYoung-Ho AhnJonathon D. RoybalXin LiuEdwin Roger Parra CuentasJaime RodriguezIgnacio I. WistubaChad J. CreightonDon L. GibbonsJohn M. HicksMary E. DickinsonJennifer L. WestK. Jane Grande-AllenSamir M. HanashMitsuo YamauchiJonathan M. Kurie

matrix biologycancer biologycollagen cross-link switchbiostatisticscancer researchoncologycancer-associated fibroblaststissue engineeringsurgical oncologytumor biologydermatologymedicinal researchcell biologytumor stroma

Optineurin Regulates Nrf2-Mediated Antioxidant Response in a Mouse Model of Paget’s Disease of Bone. Science Advances (2023)

Xiangxiang HuSing-Wai WongKaixin LiangTai-Hsien WuSheng WangLufei WangJie LiuMitsuo YamauchiBrian L. FosterJenny P.-Y. TingBaohong ZhaoHenry C. TsengChing-Chang Ko

mouse modelmedicineneuroscienceantioxidantsoxidative stressredox biologybone researchscience advancemammalian biologybone disease

Supplementary Movie 1 Cafs Spontaneously Organize Into Networks With Contractile Properties From Cancer-Associated Fibroblasts Induce a Collagen Cross-Link Switch in Tumor Stroma. (2023)

network sciencecancer biologycollagen cross-link switchstructural biologycancer researchbiological networksfragmentation effectcancer-associated fibroblastscontractile propertiessystems biologytumor biologyfibroblast growth factorsdermatologycell biologycapillary networktumor stroma

Supplementary Movie 2 Adjacent Tumor Spheroids Disorganize and Migrate on Caf Networks From Cancer-Associated Fibroblasts Induce a Collagen Cross-Link Switch in Tumor Stroma. (2023)

matrix biologycancer-associated fibroblastssurgical oncologycancer cellscell biologynetwork sciencecancer biologycancer researchtumor heterogeneitycell-matrix interactionscancer genomicsmetastasistumor biologydermatologytumor stromacollagen cross-link switchoncologycaf networkssystems biologymedicinal researchcapillary network

Comparative Genomic and Biochemical Analyses Identify a Collagen Galactosylhydroxylysyl Glucosyltransferase From Acanthamoeba Polyphaga Mimivirus. Scientific Reports (2022)

Wenhui WuJeong Seon KimAaron O. BaileyWilliam K. RussellStephen J. RichardsTiantian ChenTingfei ChenZhenhang ChenBo LiangMitsuo YamauchiHoufu Guo

biochemical analysescomparative genomicgenomicsvirologyviral evolutionmicrobial geneticsbiochemistryvirus researchmolecular biologygenome biologydermatologymolecular virologyacanthamoeba polyphaga mimivirusviral geneticsprotein sciencecollagen galactosylhydroxylysyl glucosyltransferaseclinical microbiology

Comparative Genomic and Crystal Structure Analyses Identify a Collagen Glucosyltransferase From Acanthamoeba Polyphaga Mimivirus. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Wenhui WuJeong Seon KimStephen J. RichardsChristoph BuhlhellerAaron O. BaileyWilliam RussellTiantian ChenTingfei ChenZhenhang ChenBo LiangMitsuo YamauchiHoufu Guo

comparative genomicscomparative genomicgenomicsvirologystructural biologycollagen glucosyltransferasemicrobial geneticsmolecular biologygenome biologyimmunologydermatologyanimal virusviral geneticsmicrobial systematics

Lysyl Hydroxylase 2 Mediated Collagen Post-Translational Modifications and Functional Outcomes. Scientific Reports (2022)

Masahiko TerajimaYuki TagaTomoyuki NakamuraHou-Fu GuoYukako KayashimaNobuyo Maeda-SmithiesKshitij Parag-SharmaJeong Seon KimAntonio L. AmelioKazunori MizunoJonathan M. KurieMitsuo Yamauchi

geneticscollagen post-translational modificationsscientific datadermatologycell biologyregenerative medicinefunctional outcomes

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Mitsuo Yamauchi

Sunstar Distinguished Professor

University of North Carolina at Chapel Hill

Affiliations

Adams School of Dentistry

the Graduate School

Mitsuo Yamauchi is currently serving as an Adams School Of Dentistry Sunstar Distinguished Professor at University of North Carolina At Chapel Hill.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Mitsuo Yamauchi

University of North Carolina at Chapel Hill

Sunstar Distinguished Professor

You can click a keyword to filter the displayed items

Video Presentations

Notable Scholarly Works

Notable Federal Grants

Collaborators

Generation of Bone-Specific Lysyl Hydroxylase 2 Knockout Mice and Their Phenotypes. Biochemistry and Biophysics Reports (2024)

Kenta TsuneizumiAtsushi KasamatsuTomoaki SaitoReo FukushimaYuki TagaKazunori MizunoMasataka SunoharaKatsuhiro UzawaMitsuo Yamauchi

biophysicsbiophysical chemistrymolecular biologybiochemistry

Bone Dysplasia in Hutchinson‐Gilford Progeria Syndrome is Associated With Dysregulated Differentiation and Function of Bone Cell Populations. Aging Cell (2023)

ageingbone cell populationsdysregulated differentiationdevelopmental biologydermatologybone dysplasiabiogerontology

Collagen Cross‐Linking in Oral Cancer. Oral Science International (2023)

Katsuhiro UzawaAtsushi KasamatsuMitsuo Yamauchi

geneticshealth sciencesoncologyoral biologyoral cancercell biologycollagen cross-linking

Data From Cancer-Associated Fibroblasts Induce a Collagen Cross-Link Switch in Tumor Stroma. (2023)

Optineurin Regulates Nrf2-Mediated Antioxidant Response in a Mouse Model of Paget’s Disease of Bone. Science Advances (2023)

Xiangxiang HuSing-Wai WongKaixin LiangTai-Hsien WuSheng WangLufei WangJie LiuMitsuo YamauchiBrian L. FosterJenny P.-Y. TingBaohong ZhaoHenry C. TsengChing-Chang Ko

mouse modelmedicineneuroscienceantioxidantsoxidative stressredox biologybone researchscience advancemammalian biologybone disease

Supplementary Movie 1 Cafs Spontaneously Organize Into Networks With Contractile Properties From Cancer-Associated Fibroblasts Induce a Collagen Cross-Link Switch in Tumor Stroma. (2023)

Supplementary Movie 2 Adjacent Tumor Spheroids Disorganize and Migrate on Caf Networks From Cancer-Associated Fibroblasts Induce a Collagen Cross-Link Switch in Tumor Stroma. (2023)

Comparative Genomic and Biochemical Analyses Identify a Collagen Galactosylhydroxylysyl Glucosyltransferase From Acanthamoeba Polyphaga Mimivirus. Scientific Reports (2022)

Wenhui WuJeong Seon KimAaron O. BaileyWilliam K. RussellStephen J. RichardsTiantian ChenTingfei ChenZhenhang ChenBo LiangMitsuo YamauchiHoufu Guo

Comparative Genomic and Crystal Structure Analyses Identify a Collagen Glucosyltransferase From Acanthamoeba Polyphaga Mimivirus. bioRxiv (Cold Spring Harbor Laboratory) (2022)

Wenhui WuJeong Seon KimStephen J. RichardsChristoph BuhlhellerAaron O. BaileyWilliam RussellTiantian ChenTingfei ChenZhenhang ChenBo LiangMitsuo YamauchiHoufu Guo

Lysyl Hydroxylase 2 Mediated Collagen Post-Translational Modifications and Functional Outcomes. Scientific Reports (2022)

Masahiko TerajimaYuki TagaTomoyuki NakamuraHou-Fu GuoYukako KayashimaNobuyo Maeda-SmithiesKshitij Parag-SharmaJeong Seon KimAntonio L. AmelioKazunori MizunoJonathan M. KurieMitsuo Yamauchi

geneticscollagen post-translational modificationsscientific datadermatologycell biologyregenerative medicinefunctional outcomes

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bone repair

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orthopaedic surgery

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stem cell research

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