Faculty

Institution

Unit

Venue

Ernestina Schipani

William Wikoff Smith Professor of Orthopaedic Surgery

University of Pennsylvania

Affiliations

Perelman School of Medicine

Orthopaedic Surgery

Ernestina Schipani is currently serving as an Orthopaedic Surgery William Wikoff Smith Professor of Orthopaedic Surgery at University of Pennsylvania.

Honors

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Experiences

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Education

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Ernestina Schipani

University of Pennsylvania

William Wikoff Smith Professor of Orthopaedic Surgery

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regenerative medicine bone research genetics pharmacology cell biology developmental biology endocrinology parathyroid hormone receptors tumor biology hematology membrane biology vascular biology gene expression mammalian biology bone metabolism bone homeostasis orthopaedic research hypoxia (medicine) tissue engineering medicinal research cellular physiology tissue development endocrine research stem cell research receptor (biochemistry) bone health molecular physiology liver physiology bone disease angiogenesis comparative endocrinology developmental science redox biology cartilage cell regulation bone remodeling endochondral bone development protein science cell proliferation cancer biology cellular biology bone density bone repair biological chemistry gene function clinical investigation experimental medicine signaling pathways bone development bone mass clinical physiology treatment and prevention developmental endocrinology biological function orthopedic biomechanics geriatric endocrinology molecular regulation fracture healing experimental pathology molecular pathology clinical pathology skeletal development metaphyseal chondrodysplasia limb bud mesenchyme growth plate development bone formation molecular basis osteoblastic cells transgenic mice chondrocyte survival chondrocyte proliferation epiphyseal chondrocytes primary hyperparathyroidism nucleus pulposus cells constitutive activation

Notable Scholarly Works

Notable Federal Grants

Collaborators

List of Contributors. Elsevier eBooks (2026)

digital humanitieselectronic libraryelectronic publishingenglish

The Hypoxia Signaling Pathway in the Skeleton. Elsevier eBooks (2026)

physiologyhypoxia (medicine)metabolic pathwaysoxidative stresscell metabolism

A Mouse Model of Jansen’s Metaphyseal Chondrodysplasia for Investigating Disease Mechanisms and Candidate Therapeutics. Proceedings of the National Academy of Sciences (2025)

stem cell researchmusculoskeletal researchmammalian biologystem cellsdevelopmental biologypathologybone researchcell biology

Erythroid Precursors Regulate Local Oxygen Tension and Repair Outcomes in the Bone Marrow Niche. Proceedings of the National Academy of Sciences (2025)

physiologystem cell researchheme homeostasishaematopoiesisstem cellsdevelopmental biologycell biology

Hif1α Controls Somitogenesis and Spine Development by Regulating Levels of Intracellular Oxygen in the Presomitic Mesoderm. bioRxiv (Cold Spring Harbor Laboratory) (2025)

gene expressioncell fate determinationcellular physiologyredox signalingcell signalingdevelopmental cellredox biologytranscription factorsmolecular cell biologydevelopmental biologycellular differentiationoxidative stresscell biology

Hif1 Activation Safeguards Cortical Bone Formation Against Impaired Oxidative Phosphorylation. JCI Insight (2024)

Mohd P. KhanElena SabiniKatherine BeigelGiulia LanzollaBrittany LaslowDian WangChristophe MerceronAmato GiacciaFanxin LongDeanne TaylorErnestina Schipani

impaired oxidative phosphorylationbone homeostasismolecular biologyoxidative stressbone research

Osteoblastic Erythropoietin is Not Required for Bone Mass Accrual. JBMR Plus (2024)

Giulia LanzollaChristophe MerceronMohd Parvez KhanElena SabiniAmato GiacciaErnestina Schipani

dermatologybone masshematologyregenerative medicineosteoblastic erythropoietin

Pharmacological Inhibition of Hif2 Protects Against Bone Loss in an Experimental Model of Estrogen Deficiency. Proceedings of the National Academy of Sciences (2024)

Giulia LanzollaElena SabiniKatherine BeigelMohd Parvez KhanXiaowei Sherry LiuDian WangBrittany LaslowDeanne TaylorTeresita BellidoAmato GiacciaErnestina Schipani

pharmacologyendocrinologypharmacological inhibitionbone lossexperimental modelestrogen deficiency

The Hypoxia Signature Across Skeletal Progenitor Cells. Journal of Bone and Mineral Research (2024)

Elena SabiniErnestina Schipani

physiologyhypoxia signaturestem cell researchhematologyregenerative medicineskeletal progenitor cellshypoxia (medicine)developmental biologytissue (biology)bone researchcell biology

Cell Metabolism and Bone Cells. Bone Reports (2023)

Ernestina SchipaniGeert Carmeliet

regenerative medicinebone cellscell biologybone researchcell metabolism

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Ernestina Schipani

William Wikoff Smith Professor of Orthopaedic Surgery

University of Pennsylvania

Affiliations

Perelman School of Medicine

Orthopaedic Surgery

Ernestina Schipani is currently serving as an Orthopaedic Surgery William Wikoff Smith Professor of Orthopaedic Surgery at University of Pennsylvania.

Honors

Create free account to unlock more features

Experiences

Create free account to unlock more features

Education

Create free account to unlock more features

Ernestina Schipani

University of Pennsylvania

William Wikoff Smith Professor of Orthopaedic Surgery

You can click a keyword to filter the displayed items

Notable Scholarly Works

Notable Federal Grants

Collaborators

List of Contributors. Elsevier eBooks (2026)

digital humanitieselectronic libraryelectronic publishingenglish

The Hypoxia Signaling Pathway in the Skeleton. Elsevier eBooks (2026)

physiologyhypoxia (medicine)metabolic pathwaysoxidative stresscell metabolism

A Mouse Model of Jansen’s Metaphyseal Chondrodysplasia for Investigating Disease Mechanisms and Candidate Therapeutics. Proceedings of the National Academy of Sciences (2025)

stem cell researchmusculoskeletal researchmammalian biologystem cellsdevelopmental biologypathologybone researchcell biology

Erythroid Precursors Regulate Local Oxygen Tension and Repair Outcomes in the Bone Marrow Niche. Proceedings of the National Academy of Sciences (2025)

physiologystem cell researchheme homeostasishaematopoiesisstem cellsdevelopmental biologycell biology

Hif1α Controls Somitogenesis and Spine Development by Regulating Levels of Intracellular Oxygen in the Presomitic Mesoderm. bioRxiv (Cold Spring Harbor Laboratory) (2025)

Hif1 Activation Safeguards Cortical Bone Formation Against Impaired Oxidative Phosphorylation. JCI Insight (2024)

Mohd P. KhanElena SabiniKatherine BeigelGiulia LanzollaBrittany LaslowDian WangChristophe MerceronAmato GiacciaFanxin LongDeanne TaylorErnestina Schipani

impaired oxidative phosphorylationbone homeostasismolecular biologyoxidative stressbone research

Osteoblastic Erythropoietin is Not Required for Bone Mass Accrual. JBMR Plus (2024)

Giulia LanzollaChristophe MerceronMohd Parvez KhanElena SabiniAmato GiacciaErnestina Schipani

dermatologybone masshematologyregenerative medicineosteoblastic erythropoietin

Pharmacological Inhibition of Hif2 Protects Against Bone Loss in an Experimental Model of Estrogen Deficiency. Proceedings of the National Academy of Sciences (2024)

Giulia LanzollaElena SabiniKatherine BeigelMohd Parvez KhanXiaowei Sherry LiuDian WangBrittany LaslowDeanne TaylorTeresita BellidoAmato GiacciaErnestina Schipani

pharmacologyendocrinologypharmacological inhibitionbone lossexperimental modelestrogen deficiency

The Hypoxia Signature Across Skeletal Progenitor Cells. Journal of Bone and Mineral Research (2024)

Elena SabiniErnestina Schipani

physiologyhypoxia signaturestem cell researchhematologyregenerative medicineskeletal progenitor cellshypoxia (medicine)developmental biologytissue (biology)bone researchcell biology

Cell Metabolism and Bone Cells. Bone Reports (2023)

Ernestina SchipaniGeert Carmeliet

regenerative medicinebone cellscell biologybone researchcell metabolism

1
2
3
4
5
19
10 / page

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Similar Faculty Members

Janet Rubin

Institution

University of North Carolina at Chapel Hill

orthopaedic surgery

stem cell

Beate Klara Maria Lanske

Institution

Harvard University

orthopaedic surgery

bone repair

David W. Rowe

Institution

University of Connecticut

cellular differentiation

orthopaedic surgery

Aaron James

Institution

Johns Hopkins University

regenerative medicine

bone research

Nicola C. Partridge

Institution

New York University

parathyroid gland

pharmacological research

Mitsuo Yamauchi

Institution

University of North Carolina at Chapel Hill

extracellular matrix

matrix biology

Harry Blair

Institution

University of Pittsburgh

health science

bone homeostasis

Roland Baron

Institution

Harvard University

cellular differentiation

orthopaedic surgery

Amato J. Giaccia

Institution

Stanford University

radiation oncology

cancer biology

Carlos M. Isales

Institution

Augusta University

endocrinology

metabolic health